Can magnesium be applied to the evaluation of spontaneous abnormal taste?

2016 Fiscal Year Final Research Report

• Project/Area Number: 26463182
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Social dentistry
• Research Institution: Niigata University
• Principal Investigator: FUNAYAMA Saori 新潟大学, 医歯学総合病院, 医員 (30422611)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 自発性異常味覚 / 唾液 / マグネシウム / 服用薬剤

Outline of Final Research Achievements

Phantogeusia is a perception of taste that occurs in the absence of a tastant. The most common chief complaint is bitter. The aim of this study was to investigate the cause of bitter phantogeusia. Questionnaires including medical history, medication and bitter taste sensation, and psychological tests were performed. Magnesium in unstimulated saliva and magnesium in serum were measured. Mean value of all parameters was compared between patient and control groups. Salivary magnesium level, Total GHQ30 and SDS scores were significantly higher in the patient group than in the control group. The patients group had more participants with an allergy to pollen dust than the control group, significantly. Almost patients took medication with adverse effects of dysgeusia. Based on these findings, salivary magnesium level, medication with adverse effect of dysgeusia, and medical history of allergy may be factors influencing the phantom sensation of bitterness.

Free Research Field

味覚