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2015 Fiscal Year Final Research Report

Synthesis of Escherichia coli Trap using Protein Microtube

Research Project

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Project/Area Number 26600030
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Nanomaterials chemistry
Research InstitutionChuo University

Principal Investigator

KOMATSU Teruyuki  中央大学, 理工学部, 教授 (30298187)

Co-Investigator(Renkei-kenkyūsha) AKIYAMA Motofusa  中央大学, 理工学部, 助教 (90467697)
Project Period (FY) 2014-04-01 – 2016-03-31
Keywordsナノ材料 / 蛋白質 / マイクロチューブ / 大腸菌 / 電子顕微鏡 / アルブミン / 交互積層法
Outline of Final Research Achievements

Microorganism is efficiently captured into the one-dimensional pore-space interior of protein microtube. We synthesized cylindrical hollow structure composed of human serum albumin by layer-by-layer assembly technique using microporous polycarbonate membrane, and revealed that Escherichia coli (E. coli K12) is encapsulated into the microtubes (outer diameter : 1 μm). This microtube“E. coli trap”might be applicable to eliminate enterohemorrhagic E. coli O157.

Free Research Field

生命分子化学

URL: 

Published: 2017-05-10  

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