2015 Fiscal Year Final Research Report
Development of structure-based Nanocapsule using vault particles.
| Project/Area Number |
26650020
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Structural biochemistry
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| Research Institution | Osaka University |
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Principal Investigator |
TANAKA HIDEAKI 大阪大学, たんぱく質研究所, 准教授 (40346169)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | ボルト / ナノカプセル / Ｘ線結晶構造解析 |
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| Outline of Final Research Achievements |
Vaults are large barrel-shaped ribonucleoprotein particles and are found in numerous eukaryotic species. A vault particle shell is composed of 78 MVP (Major Vault Protein) chains with 39-fold dihedral symmetry, and has a large cavity. In this study, I developed novel Nanocapsules using vault particles based on its structural information.
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| Free Research Field |
蛋白質結晶学、構造生物学
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