2016 Fiscal Year Final Research Report
Analysis for microRNA in osteo- and chondro-sarcomas
| Project/Area Number |
26670179
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Human pathology
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| Research Institution | Iwate Medical University |
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Principal Investigator |
Satoh Takashi 岩手医科大学, 医学部, 教授 (20170756)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 転移 / 骨軟部腫瘍 / miRNA |
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| Outline of Final Research Achievements |
Advances in treatment modalities for osteo-, and chondro-sarcomas (OCSs)contributes to their disease outcomes, whereas these have been still unsatisfactory in metastatic tumors of OCS. We identified overexpression of lincRNA-ARF6 OCSs cell lines with high metastatic potentiality. The lincRNA-ARF6 regulated ARF6 expression, but not related with motility and invasion of these cell lines. Further studies will be needed for contribution of non-coding RNA in OCSs metastasis.
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| Free Research Field |
人体病理
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