2016 Fiscal Year Final Research Report
Detectino of AGEs in the basement membrane in the eye, and establishment of the AGE detection clinical equipments.
| Project/Area Number |
26670755
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Ophthalmology
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| Research Institution | Kyushu University (2015-2016)
Yamaguchi University (2014) |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 眼組織 / AGE / 老年期障害 |
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| Outline of Final Research Achievements |
We tried to detect AGEs in the basement membrane in the eye, and establish the AGE detection clinical equipments. AGE can cause organ dysfunction in the various conditions, abnormalities of the basement membrane are thought to contribute to the complications of aging. Eye ball must be the easiest organ to detect AGE in the whole body. We established the best conditioned wavelength in mode-fixed titanium sapphire laser light source. It was also confirmed that by using an objective lens with a working distance of 30 mm or more, the retina and the lens are easy to evaluate.
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| Free Research Field |
眼科学、免疫学
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