2015 Fiscal Year Final Research Report
Autologus adipose-derived stem cell therapy for radiation injuries
| Project/Area Number |
26670774
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Nagasaki University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
AKITA Sadanori 長﨑大学, 病院(医学系), 講師 (90315250)
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| Project Period (FY) |
2014-04-01 – 2016-03-31
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| Keywords | 脂肪由来幹細胞 / 創傷治癒 / 放射線皮膚障害 |
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| Outline of Final Research Achievements |
We recognized the improvement of ischemia and edema each with adipose-derived stem cells transplantation in a lower extremity ischemia rat or a lower extremity lymphedema mouse which are an animal model of the radiation injury. We also recognized a further improvement effect in combination of vascularized tissue transplantation and adipose-derived stem cells transplantation than adipose-derived stem cells alone transplantation.
Radiation wounds are usually treated with adequate debridement and vascularized tissues transplantation. We think a further improvement effect in combination of vascularized tissue transplantation and adipose-derived stem cells transplantation for treatment of radiation injury.
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| Free Research Field |
創傷治癒学
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