2016 Fiscal Year Final Research Report
Establishment of iPS cells derived from keloid patients for the purpose of drug discovery
| Project/Area Number |
26670778
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Juntendo University |
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Principal Investigator |
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| Research Collaborator |
OHSHITA Takashi
TAJIMA Satoshi
|
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | ケロイド / iPS細胞 / 創薬 |
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| Outline of Final Research Achievements |
The purpose of this study was to establish iPS cells from dermal derived fibroblasts of keloid patients and induce differentiation into keloid fibroblasts to investigate mechanisms of development and disease pathology of keloid.
Through this study, however, iPS cells were not established from keloid patient-derived fibroblasts, and as a result, establishment of a method to efficiently establish iPS cells from keloid fibroblasts and to differentiate into fibroblasts could not be established.
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| Free Research Field |
医歯薬学
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