2016 Fiscal Year Final Research Report
Development of the therapeutic method for peri-implantitis using thin membranes with micro-nano structures
| Project/Area Number |
26670829
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Prosthodontics/ Dental materials science and
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | マイクローナノ構造 / 骨芽細胞 / 線維芽細胞 / 上皮細胞 / 細胞接着 / マイクログルーブ構造 / マイクロピラー構造 |
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| Outline of Final Research Achievements |
In this study, a nano imprint method was used to develop gelatin and titanium sheets with grooved and pillared structures. We investigated the effects of surfaces with micro and nano structures on adhesion and proliferation of osteoblasts, fibroblasts, and epithelial cells. However micro and nano structures accelerated adhesion and proliferation of osteoblasts and fibroblasts, those prevented epithelial cells. These results suggested that the micro and nano grooved and pillared structures effect on adhesion and orientation of osteoblasts, fibroblasts and epithelial cells.
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| Free Research Field |
歯科補綴学
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