Development of MALDI-MS-based analytical technique for biomarker discovery and diagnosis

2017 Fiscal Year Final Research Report

• Project/Area Number: 26713020
• Research Category: Grant-in-Aid for Young Scientists (A)
• Allocation Type: Partial Multi-year Fund
• Research Field: Laboratory medicine
• Research Institution: Kyushu University
• Principal Investigator: Miura Daisuke 九州大学, 農学研究院, 特任准教授 (40532627)
• Project Period (FY): 2014-04-01 – 2018-03-31
• Keywords: 質量分析 / イメージング / メタボロミクス

Outline of Final Research Achievements

A platform for biomarker discovery and diagnosis with multiple mass spectrometry (MS)-driven metabolite analytical platform were developed. This platform includes, 1. high-throughput metabolite analysis system, 2. spatiotemporally-resolved metabolite analysis system, and 3. standard-independent identification method of elemental composition for metabolite annotation. By accelerating interdisciplinary technical fusion in diverse biomedical redox-related research fields, substantial development of drug discovery tool, diagnostic methodology and instrument is in progress, and thus which lead to the establishment of new discipline of pathological metabolomics.

Free Research Field

質量分析、メタボロミクス