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2017 Fiscal Year Annual Research Report

Early identification and intervention of Japanese infants with developmental dyslexia

Research Project

Project/Area Number 26780524
Research InstitutionNational Center of Neurology and Psychiatry

Principal Investigator

北 洋輔  国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所 知的障害研究部, 室長 (90627978)

Project Period (FY) 2014-04-01 – 2018-03-31
Keywords発達性ディスレクシア / 読み書き障害 / 実験心理 / 特別支援教育 / 神経科学 / 発達障害 / 保幼少連携 / 未就学児
Outline of Annual Research Achievements

本研究では、発達性ディスレクシア(DD)のリスク児における病態解明と、神経生物学的エビデンスに基づく早期支援の提案を主目的とする。本年度は、DDに対する教育的支援の実施と、支援効果の神経生物学的検証、病態に関わる認知機能についての解明を行った。成果としては、①新規の指導法を用いたDD患児への指導で読み成績を向上させることができた②読み成績の改善に伴う脳機能の変化を明らかにした③視空間ワーキングメモリーに関わる前頭葉の脳賦活の発達過程とその異常を明らかにした。これらの知見は、本邦における先行研究と合わせてDDの病態解明の一助となるだけでなく、神経生物学的エビデンスに基づいた指導法として先駆的なものと位置づけられる。研究期間を通して、複数の研究機関との協力体制を築くことができたことが、円滑な調査や実験実績に繋がったと思われる。当初の想定をこえた研究実績が得られたことをふまえ、今後はDDの早期発見・早期支援システムの社会実装と国際比較研究につなげていくことが期待される。

  • Research Products

    (16 results)

All 2018 2017 Other

All Journal Article (9 results) (of which Peer Reviewed: 9 results,  Open Access: 2 results) Presentation (5 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results) Book (1 results) Remarks (1 results)

  • [Journal Article] Right prefrontal cortex specialization for visuospatial working memory and developmental alterations in prefrontal cortex recruitment in school-age children2018

    • Author(s)
      Suzuki Kota、Kita Yosuke、Oi Yuhei、Okumura Yasuko、Okuzumi Hideyuki、Inagaki Masumi
    • Journal Title

      Clinical Neurophysiology

      Volume: 129 Pages: 759~765

    • DOI

      https://doi.org/10.1016/j.clinph.2018.01.010

    • Peer Reviewed
  • [Journal Article] Training Attention to the Other’s Need Improves Helping Behaviors in Children with Autism Spectrum Disorder: A Behavioral Analysis Using a Two-dimensional Motion Capture System2017

    • Author(s)
      Kita Yosuke、Gunji Atsuko、Sakuma Ryusuke、Goto Takaaki、Okumura Yasuko、Inagaki Masumi
    • Journal Title

      Frontiers in Education

      Volume: 2 Pages: 50

    • DOI

      https://doi.org/10.3389/feduc.2017.00050

    • Peer Reviewed / Open Access
  • [Journal Article] The relationship between the superior frontal cortex and alpha oscillation in a flanker task: Simultaneous recording of electroencephalogram (EEG) and near infrared spectroscopy (NIRS)2017

    • Author(s)
      Suzuki K, ;Okumura Y;Kita Y, Oi Y, Shinoda H,Inagaki M:
    • Journal Title

      Neuroscience Research

      Volume: 131 Pages: 30-35

    • DOI

      https://doi.org/10.1016/j.neures.2017.08.011.

    • Peer Reviewed
  • [Journal Article] The Direct/Indirect Association of ADHD/ODD Symptoms with Self-esteem, Self-perception, and Depression in Early Adolescents2017

    • Author(s)
      Kita Yosuke、Inoue Yuki
    • Journal Title

      Frontiers in Psychiatry

      Volume: 8 Pages: 137

    • DOI

      doi: 10.3389/fpsyt.2017.00137

    • Peer Reviewed / Open Access
  • [Journal Article] Excessive hemodynamic activity in the superior frontal cortex during the flanker task in children with attention deficit hyperactivity disorder2017

    • Author(s)
      Suzuki K, Okumura Y, Kita Y, Oi Y, Yamashita Y, Goto T, Inagaki M
    • Journal Title

      NeuroReport

      Volume: 28 Pages: 828-832

    • DOI

      doi: 10.1097/WNR.0000000000000834.

    • Peer Reviewed
  • [Journal Article] Predictive factors of success in neurofeedback training for children with ADHD2017

    • Author(s)
      Okumura Yasuko、Kita Yosuke、Omori Mikimasa、Suzuki Kota、Yasumura Akira、Fukuda Ayako、Inagaki Masumi
    • Journal Title

      Developmental Neurorehabilitation

      Volume: 20 Pages: 1~10

    • DOI

      https://doi.org/10.1080/17518423.2017.1326183

    • Peer Reviewed
  • [Journal Article] Mental Health Inventory for Infants: Scale Development and Japanese Infants’ Characteristics2017

    • Author(s)
      Suto Maiko、Kita Yosuke、Suzuki Kota、Inagaki Masumi、Misago Chizuru
    • Journal Title

      Journal of Child and Family Studies

      Volume: 26 Pages: 1546~1553

    • DOI

      doi: 10.1007/s10826-017-0684-x

    • Peer Reviewed
  • [Journal Article] Pure and Short-Term Phonics-Training Improves Reading and Print-Specific ERP in English: A Case Study of a Japanese Middle School Girl2017

    • Author(s)
      Okumura Yasuko、Kita Yosuke、Inagaki Masumi
    • Journal Title

      Developmental Neuropsychology

      Volume: 42 Pages: 265~275

    • DOI

      https://doi.org/10.1080/87565641.2017.1334784

    • Peer Reviewed
  • [Journal Article] Spatial working memory encoding type modulates prefrontal cortical activity.2017

    • Author(s)
      Ohi Y, Kita Y, Suzuki K, Okumura Y, Okuzumi H, Shinoda H, Inagaki M:
    • Journal Title

      Neuro Report

      Volume: 28 Pages: 391-396

    • DOI

      doi: 10.1097/WNR.0000000000000761.

    • Peer Reviewed
  • [Presentation] Mental health problems and behavioral difficulties in preschool children with motor impairment.2017

    • Author(s)
      Kita Y, Hirata S, Suzuki K, Okumura Y, Yasunaga M, Inagaki M, Nakai A:
    • Organizer
      12th Developmental Coordination Disorder Conference
    • Int'l Joint Research
  • [Presentation] Developmental trajectories of auditory sensitivity to human voice in children with and without autism spectrum disorder2017

    • Author(s)
      Kita Y, Suzuki K, Li H, Okumura Y, Omori M, Egami C, Nakamura M, Ymashita Y, Inagaki M:
    • Organizer
      14th Asian and Oceanian Congress of Child Neurology,
    • Int'l Joint Research
  • [Presentation] Pure and short-term phonics-training improves reading and print-specific ERP in English: A case study of a Japanese middle school girl.2017

    • Author(s)
      Okumura Y, Kita Y, Inagaki M:
    • Organizer
      57th Annual Meeting of the Society for Psychophysiological Research.
    • Int'l Joint Research
  • [Presentation] Abnormal feedback-related negativity for partner’s errors in children with autism spectrum disorders.2017

    • Author(s)
      Kita Y, Suzuki K, Okumura Y, Hirata S, Okuzumi H, Inagaki M:
    • Organizer
      57th Annual Meeting of the Society for Psychophysiological Research.
    • Int'l Joint Research
  • [Presentation] 学習障害に対する脳機能の評価2017

    • Author(s)
      北洋輔
    • Organizer
      第59回日本小児神経学会学術集会
    • Invited
  • [Book] 精神医学症候群(第2版)Ⅰ -発達障害・統合失調症・双極性障害・抑うつ障害-2017

    • Author(s)
      稲垣真澄, 北洋輔, 奥村安寿子, 加賀佳美
    • Total Pages
      623
    • Publisher
      日本臨牀社
  • [Remarks] 国立精神・神経医療研究センター精神保健研究所知的障害研究部

    • URL

      http://www.ncnp.go.jp/nimh/chiteki/

URL: 

Published: 2018-12-17  

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