2015 Fiscal Year Final Research Report
The inhibitory mechanism of viral replication by lactophorin that functions in infected cells.
| Project/Area Number |
26850078
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (B)
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Food science
|
|---|
| Research Institution | Gifu University |
|---|
Principal Investigator |
INAGAKI Mizuho 岐阜大学, 応用生物科学部, 助教 (50626356)
|
|---|
| Project Period (FY) |
2014-04-01 – 2016-03-31
|
| Keywords | ラクトフォリン / ヒトロタウイルス / 感染防御 / 糖鎖 / 牛乳 / レクチン |
|---|
| Outline of Final Research Achievements |
Rotavirus is the leading cause of severe gastroenteritis in infants. 18 kDa Lactophorin (LP) , which contains in bovine skim milk, suppresses the synthesis and assembly of viral protein by interaction with the host cells. It suggests that LP inhibits the early stages of viral infection, namely adhesion, penetration, uncoating. This activity might be attributed O-link glycans in LP.
|
| Free Research Field |
食品科学
|
