Develpment of a novel technique to estimate the effects of organ position uncertainties in radiotherapy

2016 Fiscal Year Final Research Report

• Project/Area Number: 26860402
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Medical Physics and Radiological Technology
• Research Institution: Osaka University
• Principal Investigator: Akino Yuichi 大阪大学, 医学系研究科, 招へい研究員 (00722323)
• Project Period (FY): 2014-04-01 – 2017-03-31
• Keywords: 放射線治療 / 呼吸性移動 / 臓器位置不確定性 / 動体追尾照射 / 強度変調放射線治療

Outline of Final Research Achievements

When radiation is exposed to moving targets such as lung and liver tumors, respiratory motions often affect the delivered dose distribution. In this study, we developed a system which estimates delivered dose distribution for such tumors. First, we developed a technique to analyze three-dimensional tumor trajectory using cine-MRI images. Second, we developed a system to measure the accuracy of motion tracking system for moving targets. Finally, we developed a method to analyze the interplay effects, which is caused when both tumor position and beam delivery dynamically change. These techniques have enabled to estimate whether radiation is accurately delivered to the tumors which move with respiration.

Free Research Field

医学物理