Endoscopic Molecular Imaging of Barrett's carcinoma

2015 Fiscal Year Final Research Report

• Project/Area Number: 26860508
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Multi-year Fund
• Research Field: Gastroenterology
• Research Institution: The University of Tokushima
• Principal Investigator: KITAMURA Shinji 徳島大学, 大学院医歯薬学研究部, 助教 (60564490)
• Project Period (FY): 2014-04-01 – 2016-03-31
• Keywords: Barrett腺癌

Outline of Final Research Achievements

We aim to make an endoscopic diagnosis system of Barrett's carcinomas or precancerous lesions by using a molecular Imaging in this study.
Cases of Barrett's carcinomas are limited, so we carried out basic research using the colon cancer cells, which are relatively easy to collect,at first. The EGFR is exposed high frequency in colon cancer, we dicided to use the EGFR for the target of molecular imaging. We have established the method of EGFR molecular imaging of colonic cancer.We apply same method for Barrett's carcinoma. However, EGFR expression is not necessarily high in Barrett's carcinoma, imaging in the EGFR has been difficult. The new molecular target of Barrett's carcinoma is required, we are advances the current continue to study.

Free Research Field

消化器内視鏡