2015 Fiscal Year Final Research Report
Expression of activation-induced cytidine deaminase in cutaneous squamous cell carcinoma
Project/Area Number |
26860908
|
Research Category |
Grant-in-Aid for Young Scientists (B)
|
Allocation Type | Multi-year Fund |
Research Field |
Dermatology
|
Research Institution | University of Occupational and Environmental Health, Japan |
Principal Investigator |
|
Project Period (FY) |
2014-04-01 – 2016-03-31
|
Keywords | 有棘細胞癌 / 転移 |
Outline of Final Research Achievements |
To examine whether AID (activation-induced deaminase) is expressed in human squamous cell carcinoma (SCC), we performed an anti-AID immunostaining. Forty nine SCC tumors out of 97 cases were AID positive. All tumors in 8 cases with local recurrence expressed AID. All SCC specimens in 14 cases with lymph node metastasis and 2 cases with lung metastasis were positive for anti-AID immunostaining. Taken together, AID expression may be a prognostic marker for cutaneous SCC.
|
Free Research Field |
皮膚科学
|