2016 Fiscal Year Final Research Report
Study on abnormality of tumor endothelial cells and hypoxic environment of tumor.
| Project/Area Number |
26861567
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Pathobiological dentistry/Dental radiology
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| Research Institution | Hokkaido University |
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Principal Investigator |
Kondoh Miyako 北海道大学, 歯学研究科, 助教 (10631864)
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | 活性酸素種 / 血管内皮細胞 / 低酸素環境 |
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| Outline of Final Research Achievements |
We recently reported that NECs may also acquire chromosomal abnormalities by ROS accumulation due to hypoxia. I examined the behavior of the NECs in the hypoxia state.It was suggested that hypoxia brought chromosome abnormality to a NECs.We have demonstrated that hypoxia causes cytogenetic abnormalities in ECs through ROS accumulation.
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| Free Research Field |
医歯薬学
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