2016 Fiscal Year Final Research Report
Identification of laminin active sites using functional peptides
| Project/Area Number |
26870613
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Multi-year Fund |
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| Research Field |
Chemical biology
Biomolecular chemistry
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
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| Project Period (FY) |
2014-04-01 – 2017-03-31
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| Keywords | ペプチド / 細胞 / 受容体 |
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| Outline of Final Research Achievements |
Laminin is a huge protein around cells in the body, and it expresses a life phenomenon by giving various stimuli to the cell. To elucidate biological functions of laminin is thought to provide useful information for pharmaceutical field and regenerative medicine. The main biological functions of laminin are cell adhesion and cell motility. In this study, we evaluated cell adhesion and migration activity using synthetic peptides covering the amino acid sequence of laminin, and the receptor was identified.
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| Free Research Field |
ペプチド科学
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