Pathogenesis of early age-related macular degeneration using adaptive optics SLO

2015 Fiscal Year Final Research Report

• Project/Area Number: 26893131
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Ophthalmology
• Research Institution: Kyoto University
• Principal Investigator: SOTARO OOTO 京都大学, 医学(系)研究科(研究院), 講師 (10511850)
• Project Period (FY): 2014-08-29 – 2016-03-31
• Keywords: 加齢黄斑変性 / 補償光学 / 視細胞

Outline of Final Research Achievements

Adaptive optics scanning laser ophthalmoscopy revealed that cone density was decreased and cone arrangement was disrupted in eyes with early age-related macular degeneration, which was more remarkable in eyes with pseudodrusen. These results suggest that photoreceptors are damaged even in early stages of age-related macular degeneration, and photoreceptor damage may be involved in the progression to late age-related macular degeneration.

Free Research Field

眼科学