1986 Fiscal Year Final Research Report Summary

Development of bioglass coated titanium implant

Research Project

Project/Area Number	59870062
Research Category	Grant-in-Aid for Developmental Scientific Research
Allocation Type	Single-year Grants
Research Field	補綴理工系歯学
Research Institution	HIROSHIMA UNIVERSITY
Principal Investigator	TSURU Hiromichi Hiroshima University School of Dentistry, 歯学部, 教授 (90034157)
Co-Investigator(Kenkyū-buntansha)	KONDO Noriaki Hiroshima University School of Dentistry, 歯学部, 助手 (20162109) AKAGAWA Yasumasa Hiroshima University Hospital, 歯学部附属病院, 講師 (00127599) NAGASAWA Tooru Hiroshima University School of Dentistry, 歯学部, 助教授 (20034168)
Project Period (FY)	1984 – 1986
Keywords	implant / ceramic / bioglass / 病理組織
Research Abstract	To examine a possibility of clinical use of the hybrid material (Ti6Al4V with Bioglass coating) for endosseous dental implant, two experiments were performed using Japanese monkeys. (1) Initial bone healing was compared histologically between two implants. There were inserted into edentulous areas of both sides of the mandible, one by tapping and the other by non-tapping methods. Both implants were covered with a muco-periosteal flap of full thickness and allowed to heal for 3 months. All bioglass-coated implants, which ever the insertion method was, showed good healing with direct bone apposition, where as the controls without bioglass coating revealed various amonts of fibrousconnective tissue between bone and implant. (2) Bioglass implants were inserted into the mandible by non-tapping method and loaded with functional stress by means of the superstructure. After 3, 6 and 9 months of function, histological specimens were prepare. Directory bone-implant interface was obviously achived in most regions along the outline of screw-saped implants.