• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

1988 Fiscal Year Final Research Report Summary

The study on the effects of the immune response to the destruction of periodontal tissue

Research Project

Project/Area Number 61304055
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Conservative dentistry
Research InstitutionDepartment of Periodontology,Meikai University School of Dentistry

Principal Investigator

IKEDA Katsumi  Meikai University School of Dentistry, 歯学部, 教授 (50049350)

Co-Investigator(Kenkyū-buntansha) OKADA Hiroshi  Osaka University School of Dentistry, 歯学部, 教授 (40038865)
UTSUMI Nobuo  Meikai University School of Dentistry, 歯学部, 教授 (20049357)
HARA Koji  Niigata University School of Dentistry, 歯学部, 教授 (20018419)
ISHIKI Tetsuo  Niigata University School of Dentistry, 歯学部, 教授 (70018406)
AONO Masao  Kyushu University School of Dentistry, 歯学部, 教授 (70037498)
Project Period (FY) 1986 – 1988
KeywordsBone destruction / Microbial plaque / Immune response / Bone resorption / Neutrophil / Lymphocyte / Monocyte-macrophage / 結合組織破壊
Research Abstract

Local inflammatory processes induced by dental plaque bacteria are believed to play an important role in destruction of tissue during periodontal disease, although the immunological or microbiological mechanisms are not exactly understood. We have been investigated to make clear to evaluate with immunological or microbiological approach for local periodontitum destruction.
In addition, we purpose to make clear the periodontal disease process (occurance-its destruction) by study plan and method to catch immunological mechanism (neutrophilic leukocyte, monocyte, macrophage, and lymphocyte, etc.) in dental plaque, bacteria, and peripheral blood, or in experimental gingivitis and periodontitis of animal gingive and alveolar bone, or bone resorption assay in vitro.
These investigation have given us the results and suggesting data to make clear immunological mechanism for destruction of periodontal tissue.

  • Research Products

    (15 results)

All Other

All Publications (15 results)

  • [Publications] K.IKEDA 他: Advances in Dental Research. 2. 368-371 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.IKEDA 他: 歯科基礎医学会雑誌. 30. 848-850 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.OKADA 他: Advances in Dental Research. 2. 364-367 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.YAJIMA: Advances in Dental Research. 2. 228-233 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.YAJIMA: Histochemistry. 90. 245-253 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.TAKIGUCHI 他: Biochemica et Biophysica Acta. 971. 121-126 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.TAKIGUCHI 他: Life Sciences. 43. 889-896 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.TAKIGUCHI 他: International journal of biochemistry. 19. 489-493 (1987)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.OKADA 他: "Recent advances in clinical periosontology" J.Ishikawa et al., 355-358 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] yoshiko MARUMOTO.: "Effects of culture supernatants of leukocytes from periodontal patients on monocyte-mediated hydroxyapatite resorption" Advances in Dental Research. 2. 368-371 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiroshi OKADA.: "The function of gingival lymphocytes on the establishment of human periodontitis" Advances in dental Research. 2. 364-367 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Toshihiko YAJIMA.: "collagen remodeling in wound healing by gingival fibroblasts in vitro" Advances in dental Research. 2. 228-233 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hisashi,TAKIGUCHI.: "Phospholipase A_2 in macrophage plasma membrane releases arachidonic acid from phosphatidylinositol" Biochimica et Biophysica Acta. 971. 121-126 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yasuko SHIBATA.: "Recognition of acidic phospholipase A_2 activity in plasma membranes of resident peritoneal macrophages" Life Sciences. 43. 889-896 (1988)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiroshi OKADA.: Recent advances in clinical periodontology. J.Ishikawa, et al, 355-358 (1988)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 1990-03-20  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi