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1989 Fiscal Year Final Research Report Summary

The interrelationship between each gut organ modulated by gastrointestinal hormones

Research Project

Project/Area Number 61440060
Research Category

Grant-in-Aid for General Scientific Research (A)

Allocation TypeSingle-year Grants
Research Field Digestive surgery
Research InstitutionKYOTO UNIVERSITY

Principal Investigator

TOBE Takayoshi  1st Department of Surgery, Faculty of Medicine, Kyoto University. Professor, 医学部, 教授 (70025641)

Co-Investigator(Kenkyū-buntansha) INOUE Kazutomo  1st Department of Surgery, Faculty of Medicine, Kyoto University. Instructor, 医学部, 講師 (90168435)
YAJIMA Haruaki  Niigata Pharmacy College. Chancellor, 学長 (00025678)
HAMASHIMA Yoshihiro  Kyoto Women College. Chancellor, 学長 (00089103)
Project Period (FY) 1986 – 1989
Keywordschronic dog with pancreatic and gastric fistulas / chronic dog with biliary, pancreatic and gastric fistulas / splanchnic circulation / gastrointestinal hormones / synthetic human CCK-33 / pancreatoduodenectomy / gallbladder dysfunction after gastrectomy / segmental autotransplantation of the pancreas
Research Abstract

Summary of research results of this project is as follows. 1) Clarification of the relationship between biliary and pancreatic secretions and the released of gastrointestinal hormones in the conscious state. 2) Clarification of the physiological changes of splanchnic circulation by simultaneous use of laser Doppler flowmetry and ultrasonic transit-time flowmeter. 3) Clarification of the physiological significance of larger molecular forms of CCK 4) Evaluation of Billroth I type of reconstruction as a physiological and pertinent reconstruction procedure after pancreatoduodenectomy in relation to the release of gastrointestinal hormones 5) Clarification of the mechanism of gaubladder dysfunction gastrectomy with special reference to changes of release of gastrointestinal hormones 6) Observation on the relatively well preservation of the hemodynamics of the segmental autotransplanted pancreas.

  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] Inoue,K.: "Effect of cynthetic chicken and porcine vasoactive intestinal peptide on pancreatic blood flow in dogs" Neuropeptides. 7. 207-217 (1986)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Inoue,K.: "Release of cholecystokinin and gallbladder contraction before and after gastrectomy" Ann.Surg.205. 27-32 (1987)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Inoue,K.: "Plasma cholecystokinin and pancreatic polypeptide response after radical pancreatoduodenectomy with Billroth I and Billroth II type of reconstruction" Ann.Surg.206. 148-154 (1987)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kogire,M.: "Effects of synthetic human gastric inhibitory polypeptide on splanchnic circulation in dogs" Gastroenterology. 95. 1636-1640 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Doi,R.: "Role of sulphated tyrosine residue in influencing the biological activity of human cholecystokinin-33" Biochem.Biophys.Res.Commun. 153. 1209-1213 (1988)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Inoue,K.: "Total small bowel resection inhibited bombesin-stimulated release of cholecystokinin and pancreatic polypeptide in anesthetized cats" J.Surg.Res.47. 87-91 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 井上一知: "消化管ホルモンVII" 医学図書出版株式会社, 5 (1987)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 井上一知: "消化器病セミナ-37,消化管ホルモンー最近の進歩" へるす出版株式会社, 11 (1989)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Inoue, K.: "Effect of synthetic chicken and porcine vasoactive intestinal peptide on pancreatic blood flow in dogs" Neuropeptides. 7. 207-217 (1986)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Inoue, K.: "Release of cholecystokinin and gallbladder contraction before and after gastrectomy" Ann. Surg. 205, 27-32, 1987.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Inoue, K.: "Plasma cholecystokinin and pancreatic polypeptide response after radical pancreatoduodenectomy with Billroth I and Billroth II type of reconstruction" Ann. Surg. 206, 148-154, 1987.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kogire, M.: "Effects of synthetic human gastric inhibitory polypeptide on splanchnic circulation in dogs" Gastroenterology 95, 1636-1640, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Doi, R.: "Role of sulphated tyrosine residue in influencing the biological activity of human cholecystokinin-33" Biochem. Biophys. Res.Commun. 153, 1209-1213, 1988.

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Inoue, K.: "Total small bowel resection inhibited bombesin-stimulated release of cholecystokinin and pancreatic polypeptide in anesthetized cats" J. Surg. Res. 47, 87-91, 1989.

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1993-03-26  

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