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1988 Fiscal Year Final Research Report Summary

Biomedical studies on the biological response to stimulation by acupuncture and moxibustion.

Research Project

Project/Area Number 62304069
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field 医学一般
Research InstitutionKansai College of Acupuncture Medicine

Principal Investigator

KAWAMATA Junichi  Kansai College of Acupuncture Medicine, 教授 (20029747)

Co-Investigator(Kenkyū-buntansha) KUMAZAWA Takao  The Research Institute of Environmental Medicine, Nagoya University, 環境医学研究所, 教授 (20022775)
WATARI Nakazo  Medical School, Nagoya City University, 医学部, 教授 (40079976)
KASAHARA Takako  Showa University School of Medicine, 医学部, 助教授 (30112717)
TAKESHIGE Chifuyu  Showa University School of Medicine, 医学部, 教授 (30053763)
KIMURA Michio  Kansai College of Acupuncture Medicine, 教授 (50111745)
Project Period (FY) 1987 – 1988
KeywordsAcupuncture / Analgetic action / Acupoints / Receptors / Immunity / 遅延型過敏症
Research Abstract

[Purpose of Research ] Morphological and functional analyses of the clinical effects of acupuncture and /or moxibustion (AM) by bimedical research.
[Methods]1. Physiological and biochemical studies on analgetic effects of AM. 2. Pharmacological, biochemical and immunological studies on the effects of AM on the immuno-defense mechanisms in man and animals. [Results] 1. studies on the analgetic effects of AM TAKESHIGE studied on the analgetic effects of acupuncture stimulation comparatively at acupoints and non-acupoints by neurophysiological experiments. He also studied on the effects of AM on a model system prepared from gastrocnemius muscle of guinea pig. KUMAZAWA claimed that polymodal receptors played an important role in analgetic action of AM. He also demonstrated the resemblance of the enhancing action of fever or serotonin at the site of inflammation on the stimulating action of bradykinin with the action of AM.
2. Effects of AM on the immuno-defense mechanisms of man and animals. SAKAMOTO, KASAHARA, and KIMURA demonstrated remarkable inhibiory effect of moxibustion on the delayed type hypersensitivity in mice. KIMURA observed the inhibitory effect of the extract of the moxa on degranulation of mouse ascites mast cells. KAWAMATA demonstrated preliminarily the effect of moxibustion on human interferon producing activity of healthy adults.
3. Morphological studies on acupuncture and meridians. WATARI demonstrated the close relationship of main acupoints with human tissues (nerves, blood vessels, muscles, bones, ligaments) on human cadavers by macroanatomical studies.
[Plans for future studies] Studies are being planned to develop above described subjects and analgetic action and enhancing effects of AM on immuno-defense mechanisms in particular.

  • Research Products

    (44 results)

All Other

All Publications (44 results)

  • [Publications] 曾澤重勝: 昭医会誌. 48. 673-680 (1988)

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  • [Publications] 岡崎雅子: 全日本鍼灸学会誌. 38. 188-194 (1988)

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  • [Publications] 坂本浩二: 全日本鍼灸学会誌. 38. 320-325 (1988)

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  • [Publications] 武重千冬: 麻酔. 36. 1498-1505 (1987)

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  • [Publications] 郭試諭: 昭医会誌. 48. 493-499 (1988)

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  • [Publications] 黄顕奮: 昭医会誌. 48. 485-492 (1988)

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  • [Publications] 五十嵐治: 昭医会誌. 48. 501-505 (1988)

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  • [Publications] Kumazawa,Takao: J.Neurophysiol.57. 702-711 (1987)

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  • [Publications] Kumazawa,Takao: Pain. 28. 255-264 (1987)

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  • [Publications] Kumazawa,Takao: Progress in Brain Research. 74. 325-330 (1988)

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  • [Publications] Mizumura,Kazue: Pfl〓gers Arch.411. 27-33 (1988)

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  • [Publications] Kruger,Lawrence: Somatosense Res.5. 373-380 (1988)

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  • [Publications] Kumazama,Takao: Environ,Med.32. 1-20 (1988)

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  • [Publications] 熊澤孝朗: 医学のあゆみ. 147. 1017-1020 (1988)

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  • [Publications] 熊澤孝朗: 日本生理学雑誌. 51. 1-15 (1988)

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  • [Publications] 豊田勝良: 解剖学雑誌. 63. 385-385 (1988)

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  • [Publications] 渡仲三: 全日本鍼灸学会誌. 38. 41-41 (1988)

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  • [Publications] 山田鑑昭: 全日本鍼灸学会誌. 38. 75-75 (1988)

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  • [Publications] Kimura,Michio: Amer.J.Chinese Med.56. 159-167 (1988)

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  • [Publications] Tohya,Kazuo: Amer.J.Chinese Med.57. 915-921 (1989)

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  • [Publications] 渡仲三: 国外医学(中医中葯). 10. 90-95 (1988)

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  • [Publications] 熊澤孝朗: "Pain-痛みの基礎と臨床「受容器-構造と機能」" 朝倉書店, 12 (1988)

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  • [Publications] AIZAWA, Shigekatsu.: "Effects of simple moxibustion on microrovascular permeability in mice. (in Japanese)" J. Showa Med. Assoc.48. 673-680 (1988)

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  • [Publications] OKAZAKI, Masako.: "Effect of single moxibustion on platelet aggregation and ATP-release in mice. (in Japanese)" J. Jap. Soc. Acupuncture. 38. 188-194 (1988)

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  • [Publications] SAKAMOTO, Koji.: "Changes in content of blood serum through moxibustion on acupoint equivalents. (in Japanese)" J. Jap. Sco. Acupuncture. 38. 320-325 (1988)

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  • [Publications] TAKESHIGE, Chifuyu.: "Mechanism of Acupuncture Analgesia.(in Japanese)" J. Jap. Anaestegiology. 36. 1498-1505 (1987)

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  • [Publications] GUO, Shi Yu.: "Acupuncture afferent and efferent pathways in the hypothalamic arcuate nucleus. (in Japanese)" J. Showa Med. Assoc.48. 493-499 (1988)

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  • [Publications] HUANG, sien Fun.: "Identity of the central analgesia producing mechanism in hoku point stimulation with taht in tsu sanri point stimulation. (in Japanese)" J. Showa Med. Assoc.48. 485-492 (1988)

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  • [Publications] IGARASHI, Osamu.: "Effect of proglunide on morphine tolerance in acupuncture analgesia. (in Japanese)" J. Showa Med. Assoc.48. 501-505 (1988)

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  • [Publications] KUMAZAWA, Takao.: "Response properties of polymodal receptors studied using in vitro testis superior spermatic nerve preparation of dogs." J. Neurophysiol.57. 702-711 (1987)

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  • [Publications] KUMAZAWA, Takao.: "Thermally potentiated responses to algesic substancse of visceral noci-ceptors." Pain. 28. 255-264 (1987)

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  • [Publications] KUMAZAWA, Takao.: "Modulation of testicular polyodal receptor activities" Progress in Brain Research. 74. 325-330 (1988)

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  • [Publications] MIZUMURA, Kazue.: "Respiratory changuced by activation of testicular afferents in dogs." Pfl gers Arch.411. 27-33 (1988)

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  • [Publications] KRUGER, Lawrence.: "Observations on electrophysiologically characterized receptive fields of thin testicular afferent axons:a preliminary note on the analysis of fine structural specializations of polymodal receptors." Somatosense Res.5. 373-380 (1988)

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  • [Publications] KUMAZAWA, Takao.: "Opioids and autonomic functions under abnormal environments." Environ. Med.32. 1-20 (1988)

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  • [Publications] KUMAZAWA, Takao.: "As a basis for considering "Pain". (in JApanese)" Igaku no Ayumi. 147. 1017-1020 (1988)

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  • [Publications] KUMAZAWA, Takao.: "Pain and polymodal receptor. (in Japanese)" J. Physiol. Soc. Jap.51. 1-15 (1989)

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  • [Publications] TOYODA, Katsuyoshi.: "Macroscopic studies on the relationship between the meridians (acupoints) and anatomical elements in the human upper limbs.(abstract, in Japanese)" Acta Anatomica Nipponica. 63. 385-385 (1988)

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  • [Publications] WATARI, Nakazo.: "Miracle of oriental medicine:Search for Acupoints. (abstract, in Japanese)" J. Jap. Soc. Acupuncture. 38. 41-41 (1988)

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  • [Publications] YAMADA, Kansho.: "An anaatomical study of meridian and acupoints.(abstract, in Japanese)" J. Jap. Soc. Acupuncture. 38. 41-41 (1988)

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  • [Publications] WATARI, Nakazo.: "Outline of the acupuncture points." J. Chin. Med. and Pharmacology,Supplement(Guowai Yixue). 10. 90-95 (1988)

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  • [Publications] KIMURA, Michio.: "An electron microscopic stydy of the acupuncture or moxibustion stimulated regional skin and lymhp nod in experimental animals." Amer. J. Chin. Med.56. 159-167 (1988)

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  • [Publications] TOHYA, Kazuo.: "Suppression of the DTH reaction in mice by means of moxibustion at electropermeable points." Amer. J. Chin. Med.57. 915-921 (1989)

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  • [Publications] KUMAZAWA, Takao.: Receptors-Structure and Function(in Pain-Basal and Clinical Studies on Pain) (in Japanese). Asakura Shoten, 12 (1988)

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Published: 1990-03-20  

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