Quantification of relative coronary arterial stenosis

1988 Fiscal Year Final Research Report Summary

• Project/Area Number: 62480294
• Research Category: Grant-in-Aid for General Scientific Research (B)
• Allocation Type: Single-year Grants
• Research Field: Thoracic surgery
• Research Institution: Gifu University, School of Medicine
• Principal Investigator: HIROSE Hajime Gifu University, School of Medicine, Professor, 医学部, 教授 (20101272)
• Co-Investigator(Kenkyū-buntansha): KOKUBO Mitsuharu Gifu University, School of Medicine, 医学部附属病院, 助手 (00170225)
• Project Period (FY): 1987 – 1988
• Keywords: coronary artery / coronary sclerosis / coronary angiography / 冠動脈狭窄度評価法

Research Abstract

This study was designed to develop a new method to gqantificate relative coronary arterial stenosis. The idea was based on that oppacity representing the volume of contrast medium was proportional to the relative stenosis of coronary artery. The system was consisted of coronary density analyzer (CDA) with a 1024^*1024 pixel matrix andan 8-bit gray scale. In tube-model experiments,% relative stenosis assesed by this CDA had linear relationships with direct measurements of coronary arterial stenosis. This relationships were affected by concentration of contrast medium.
In coronary-model experiments, we evaluated three-dimensional reconstruction of the space-density curves of bi-palne coronary angiography. % relative stenosis assesed by this CDA had linear relationships with direct measurements of coronary arterial stenosis. This relationships were severly affected by wrong dicision of the coordinate axis.
Thus densitometric analysis of % relative stenosis of coronary artery allowes three-dimensional assessment and might correlate with direct measurement of coronary arterial stenosis.