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1990 Fiscal Year Final Research Report Summary

Role of Fluctuations in Biological Signal Transmission.

Research Project

Project/Area Number 63300007
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field 広領域
Research InstitutionTokyo Institute of Technology

Principal Investigator

MUSHA Toshimitsu  Tokyo Inst. of Tech, Dept. of Applied Electronics, Prof., 大学院・総合理工学研究科, 教授 (70016319)

Co-Investigator(Kenkyū-buntansha) KAWAKUBO Tatsuyuki  Tokyo Inst. of Tech., Faculty of Science, Prof., 理学部, 教授 (10016040)
SATO Syunsuke  Osaka University, Faculty of Engineering Science, Prof., 基礎工学部, 教授 (60014015)
KUSHIDA Takashi  Osaka University, Faculty of Science, Prof., 理学部, 教授 (00013516)
YAMAMOTO Mitsuaki  Tohoku University, Faculty of Engineering, Prof., 工学部, 教授 (40004618)
SAWADA Yasugi  Tohoku Univ., Research Inst. of Electrical Communication, Prof., 電気通信研究所, 教授 (80028133)
Project Period (FY) 1988 – 1990
Keywordsfluctuations, / coding, / biological information, / self-organization, / phase transition, / statistical physics / rhythm / the same period
Research Abstract

(1) Mechanism of coding of biological signals and its role in self-protection against external stimulations and its fluctuations, and (2) the function of fluctuations contained in biological information transmission in relation to perception, cognition, judgment and memory. These two items are main targets of the present research. These subjects of research have not fully accomplished during the 3-year research, but remarkable progress has been achieved toward them through four meetings we had. The details of the achievements are given in the final report. We have found various positive phases of fluctuation phenomena in bodily motion of bacteria, heart rate, coherence of brain signals observed on the scalp and in brain cells. Meanings of fluctuations in spontaneous discharge intervals of cell membranes and in self-organization have been discussed from various respects. Phase transition of protein molecules and dynamics of nonequilibrium open systems were discussed from a statistical mechanical point of view. Topics on time reversibility, stationarity, and detailed balance of the nonequilibrium open system were found to be very important concepts in understanding biological phenomenon. Conclusively, a variety of problems have been discussed on biological functions from a physical point of view and a further progress is expected toward the final goal of the present research in the future.

  • Research Products

    (70 results)

All Other

All Publications (70 results)

  • [Publications] I.Hatta: "“Thermal Diffusivity Measurents of Thin Films and Multilayered CompositeS"" Int J.Thermo. 11. 293-303 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Matuoka,S.Kato,M.Akiyama,Y.Amemiya,and I.Hatta: "“Temperature Dependence of the Ripple Structure in DimyristoylーPhosphatidylcholine Studied by Synchrotron XーRay SmallーAngle Diffraction"" Biochim.Biophys.Acta. 1028. 103-109 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 佐藤 俊輔: "“生体信号とスペクトル解析法"" BME. 4. 51-57 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Ueda,T.Nakagaki,and T.Yamada: "“Dynamic Organization of ATP and Birefringent Fibrils During Free Locomotion and Galvanotaxis in the Plasmodium of Physarum Plycephalum"," J.Cell Biol.110. 1097-1102 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Nakagaki,J.Oda,H.Koizumi,T.Fukaya,C.Yasui,and T.Ueda: "“Ultraviolet Action Spectrum for Intracellular Free Ca^<2+> Increase in Human Epideramal Keratinocytes"" Cell Struc.Func.15. 175-179 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Kaneko,J.Takimoto,Y.Usami,and K.Kitahara: "“Gas Kinetic Approach for ElectronーIon Recombination Rate Constant in Dense Media"" J.Phys.Soc.Japan. 59. 56-65 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] X.Hu and M.Suzuki: "“An Approach to Critical Phenomena from One Subsystem Based on the CAM Analysis"" J.Phys.A. 23. 3051-3060 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] N.Kawashima,M.katori,C.Tsallis,and M.Suzuki: "“Systematic Approach to Critical Phenomena by the Extended Variational Method and CoherentーAnomaly Method"" Int.J.Mod.Phys.B. 4. 1409-1422 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Fujiki,M.Katori,and M.Suzuki: "“Study of Coherent Anomalies and Critical Exponents Based on HighーLevel ClusterーVariation Approximations"" J.Phys.Soc.Japan. 59. 2681-2687 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Tohnoe,S.Kai,and M.Imasaki: "“Surface Effect on the Polarization Reversal of Ferroelectric Liquid Crystal 8S1^*" Liquid Crystal. 5. 1149-1157 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Kai,W.Zimmermann,and M.Andoh: "“Turbulence 1ー Turbulence 2 Transition in Electrohydrodymanic Convection"" Mod.Phys.Lett.B4. 767-774 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Kushida,A.Kurita,Y.Kanematsu,and Y.Touyama: "“HoleーBurning Kinetics in Biomolecules and Polymers"" Can.J.Phys.68. 1023-1026 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Nakamura,T.Yasda,K.Kitahara,and M.Kohmoto: "“Spin Depolarization on a Linear Chain with QuasiーPeriodic Larmol Frequencies"" J.Phys.Soc.Japan. 59. 826-828 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Harayama and Y.Aizawa: "“PoincareーBirkhoff Chains in the Critical Regime Between Chaos and Torus"" Prog.Theor.Physics. 84. 23-27 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Kikuchi and Y.Aizawa: "“Lyapunov Exponent of the MultiーErgodic Motions in Hamiltonian Systems"" Prog.Theor.Physics. 84. 563-567 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Yamamoto: "“脳単一ニュ-ロンの1/fゆらぎ"" 計測と制御. 29. 1034-1042 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] F.Gruneis,M.Nakao,and M.Yamaamoto: "“Counting Statistics of 1/f Fluctuations in Neuronal Spike Trains"" Biol.Cybern.62. 407-413 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 北嶋 巌、木下 浩信、八田 浩一、岡井 善四郎、岩澤 宏: "“気体分子の励起状態におけるCARS測定ーSF_6のエネルギ-構造と励起・緩和ー"" レ-ザ研究. 18. 732-740 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Iwasawa: "“A Golval theory of a Biological System as an Open NonーEquilibrium System"" IEIC. NLP89ー86. 25-30 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Kawakubo and K.Fukunaga: "“Oscillatory Behavior of a Water/Oil Interface System in Response to CurrentーClamp and VoltageーClamp Stimulation"" Biophys.Chem.35. 113-117 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Hirano,Y.Tsuchiya,and T.Kawakubo: "“Excitatory Potential of Artificial Membrane in Response to Current Pulse Stimulation"" Biophys.Chem.36. 133-139 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] N.Takahashi,Y.Hanyu,T.Musha,R.Kubo,and G.Matsumoto: "“Global Bifurcation Structure in Periodically Stimulated Giant Axons of Squid"" Physica. D43. 318-334 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Nomura,G.Matsumoto,and S.Fujiwara: "“A Binocular Model for the Simple Cell"" Biol.Cybern.63. 237-242 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Toko,T.Yoshida,K.Hayashi,T.Fujiyoshi,M.Souda,and K.Yamafuji: "“Disappearance of Electric Spatial Pattern in a Bean Root under Circumstance in Nitrogen Gas"" J.Phys.Soc.Japan. 59. 370-376 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Toko,M.souda,T.Matsuno,and K.Yamafuji: "“Oscillations of Electrical Potential along a Root of a Higher Plant"" Biophys.J.57. 269-279 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Agu,K.Schimizu,and S.Okawa: "“An OffーEquilibrium Property of Current Fluctuation Passing through Electrical Resistors"" Jpn.J.Appl.Phys.29. 1520-1522 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Yamanaka and M.Agu: "“A Probabilistic Model of Neural Networks with Static Attractors"" IEEE Trans.Man and Cybernetics. 20. 921-922 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Toyotama: "“Oriented Immolbilization of Bacterial Photosynthetic Membrane"" Appl.Microbiol.Biotech.32. 544-549 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Nishifuji,K.Harada,and K.Hirakawa: "“SpatioーTEmporal Dynamics of Alpha Rhythms in terms of Its Envelope and Phase"" Brain Topo.3. 260-261 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Yoshikawa,K.Fukunaga,and H.Kawakami: "“A TriーPhasic Mode ia Stable When Three NonーLinear Oscillators Interact with Each Other"" Chem.Phys.Lett.174. 203-207 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] L.M.Ricciardi and S.Sato,: "Problems in“Lectures in Applied Mthematics and Informatics,″ed.by L.M.Ricciardi," Manchester Univ.Press., (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] K.Kitahara,K.Seki and S.Suzuki: "On the Spatial Correlations in ReactionーDiffusion Systems in Nonequilibrium Conditions,ed.by A.Blomen and J.Klafter," World Scientific,(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Suzuki: "Coherent-Anomaly Method and Super-Effective Field Theory,ed.by M.D.Covtino and S.M.Rezende," Woeld Scientific,(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] M.Suzuki: "“Quantum Simulation of Condensed Phenomena",ed.by J.D.Doll and J.E.Gubernatis," World Scientific,(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Kobatake,T.Ueda and K.Matsumoto,: "“Biosensors and Biocomputers"" plenum press, (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Ueda K.Matsumoto and Y.Kobatake: "“Molecular and Biological Physics" Kluwer Academic publ.,(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] T.Kaminuma and G.Matsumoto,: "BIOCOMPUTERS,The Next Generation from Japan," Chapman and Hall,(1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Nakata and k.Yoshikawa: "J.Molec.Elec." “A Novel Method for the Recognition of Molecular Chirarity from the Frequency Modulation of Nonlinear Lectrochemical Oscillation", 95-98 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Amari: "Prac.IEEE" “Mathematical Foundations of Neurocomputing", 1443-1463 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S.Amari: "Statistics" “Discussion to SmallーSample Distributional Properties of Nonlinear Regression Estimators(a Geometric Approach)by A.Pazman, 323-367 (1990)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] X. Hu and M. Suzuki: ""An Approach to Critical Phenomena from One Subsystem Based on the CAM Analysis"" J. Phys. A. 23. 3051-3060 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] N. Kawashima, M. Katori, C. Tsallis, and M. Suzuki,: ""Systematic Approach to Critical Phenomena by the Extended Variational Method and Coherent-Anomaly Method"" Int. J. Mod. Phys. B. 4. 1409-1422 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Fujiki, M. Katori, and M. Suzuki,: ""Study of Coherent Anomalies and Critical Exponents Based on High-Level Cluster-Variation Approximations"" J. Phys. Soc. Japan. 59. 2681-2687 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M. Tohnoe, S. Kai and M. Imasaki,: ""Surface Effect on the polarization Reversal of Ferroelectric Liquid Crystal 8SI^*"" Liquid Crystal. 5. 1149-1157 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Kai, W. Zinnermann, and M. Andoh,: ""Turbulence 1-Turbulence 2-Transition in Electrohydrodymanic Convection"" Mod. Phys. Lett.B4. 767-774 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Kushida, A. Kurita, Y. Kanematsu, and Y. Touyama,: ""Hole-Burning Kinetics in Biomolecules and Polymers"" Can. J. Phys.68,. 1023-1026 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] I. Hatta,: ""Thermal Diffusivity Measurements of Thin Films and Multilayered Composites"" Int, J. Thermo.,. 11. 293-303 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Matuoka, S. Kato, M. Akiyama, Y. Amemiya, and I. Hatta,: ""Temperature Dependence of the Ripple Structure in Dimyristoyl-Phosphatidylcholine Studied by Synchrotron X-Ray SmallーAngle Diffraction"" Biochim. Biophys. Acta,. 1028. 103-109 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Ueda, T. Nakagaki, and T. Yamada,: ""Dynamic Organization of ATP and Birefringint Fibrils During Free Locomotion and Galvanotaxis in the Plasmodium of Physarum Plycephalum"" J. Cell Biol.,. 110. 1097-1102 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Nakagaki, J. Oda, H. Koizumi, T. Fukaya, C. Yasui, and T. Ueda,: ""Ultraviolet Action Spectrum for Intracellular Free Ca^<2+> Increase in Human Epideramal Keratinocytes"" Cell Struc. Func.15. 175-179 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K. Kaneko, J. Takimoto, Y. Usami, and K. Kitahara,: ""Gas Kinetic Approach for Electron-Ion Recombination Rate Constant in Dense Media"" J. Phys. Soc. Japan. 59. 56-65 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M. Nakamura, T. Yasuda, K. Kitahara, and M. Kohmoto,: ""Spin Depolarization on a Linear Chain with Quasi-Periodic Larmor Frequencies"" J. Phys. Soc. Japan. 59. 826-828 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Harayama, and Y. Aizawa,: ""Poincare-Birkhoff Chains in the Critical Regime Between Chaos and Torus"" Prog. Theor, Physics. 84. 23-27 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Y. Kikuchi, and Y. Aizawa,: ""Lyapunov Exponent of the Multi-Ergodic Motions in Hamiltonian Systems"" Prog. Theor. Physics. 84. 563-567 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] F. Gruneis, M. Nakao, and M. YamamotoO, M.: ""Counting Statistics of 1/f Fluctuations in Neuronal Spike Trains"" Biol. Cybern. 62. 407-413 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H. Iwasawa,: ""A Golval Theory of a Biological System as an Open Non-Equilibrium System"" IEIC. NLP 89-86,. 25-30 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Kawakubo, and K. Fukunaga,: ""Oscillatory Behavior of a Water/Oil Interface System in Response to Current-Clamp and Voltage-Clamp Stimulation"" Biophys. Chem,. 35,. 113-117 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] T. Hirano, Y. Tsuchiya, and T. Kawakubo,: ""Excitatory Potential of Artificial Membrane in Response to Current Pulse Stimulation"" Biophys. Chem.,. 36. 133-139 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] N. Takahashi, Y. Hanyu, T. Musha, R. Kubo, and G. Matsumoto,: ""Global Bifurcation Structure in Periodically Stimulated Giant Axons of Squid"" Physica,. D43. 318-334 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M. Nomura, G. Matsumoto, and S. Fujiwara,: ""A Binocular Model for the Simple Cell"" Biol. Cybern.63. 237-242 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K. Toko, T. Yoshida, K. Hayashi, T. Fujiyoshi, M. Souda, and K. Yamafuji,: ""Disappearance of Electric Spatial Pattern in a Bean Root under Circumstance in Nitrogen Gas"" J. Phys. Soc. Japan. 59. 370-376 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K. Toko, M. Souda, T. Matsuno, and K. Yamafuji,: ""Oscillations of Electrical Potential along a Root of a Higher Plant"" Biophys. J.57. 269-279 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] M. Agu, K. Schimizu, and S. Okawa,: ""An Off-Equilibrium Property of Current Fluctuation Passing through Electrical Resistors"" Jpn. J. Appl. Phys.29,. 1520-1522 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K. Yamanaka and M. Agu: ""A Probabilistic Model of Neural Networks with Static Attractors"" IEEE Trans. Man and Cybernetics. 20. 921-922 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] H. Toyotama: ""Oriented Immobilization of Bacterial Photosynthetic Membrane"" Appl. Microbiol. Biotech.32. 544-549 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Nishifugi, K. Harada, and K. Hirakawa: ""Spatio-Temporal Dynamics of Alpha Rhythms in terms of Its Envelope and Phase"" Brain Topo.,. 3. 260-261 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] K. Yoshikawa, K. Fukunaga, and H. Kawakami: ""A Tri-Phasic Mode ia Stable when Three Non-Linear Oscillators Interact with Each Other"" Chem. Phys. Lett.174. 203-207 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Nakata, and K. Yoshikawa,: ""A Novel Method for the Recognition of Molecular Chirarity from the Frequency Modulation of Nonlinear Lectrochemical Oscillation"" J. Molec. Elec.6. 95-98 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Amari: ""Mathematical Foundations of Neurocomputing"" Proc. IEEE. 78. 1443-1463 (1990)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] S. Amari: ""Discussion to Small-Sample Distributional Properties of Nonlinear Regression Estimators(a Geometric Approach)by A. Pazman" Statistics. 21. 323-367 (1990)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1993-08-12  

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