Steering group for the LipoQuality program project

• Project Area: Quality of lipids in biological systems
• Project/Area Number: 15H05897
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Institute of Physical and Chemical Research
• Principal Investigator: ARITA Makoto 国立研究開発法人理化学研究所, 生命医科学研究センター, チームリーダー (80292952)
• Co-Investigator(Kenkyū-buntansha): 有田 正規 国立遺伝学研究所, 情報研究系, 教授 (10356389) ; 瀬藤 光利 浜松医科大学, 国際マスイメージングセンター, センター長 (20302664) ; 反町 典子 国立研究開発法人国立国際医療研究センター, その他部局等, 分子炎症制御プロジェクト長 (30217468) ; 藤本 豊士 順天堂大学, 医学(系)研究科(研究院), 特任教授 (50115929) ; 佐々木 雄彦 東京医科歯科大学, 難治疾患研究所, 教授 (50333365) ; 矢冨 裕 東京大学, 医学部附属病院, 教授 (60200523) ; 横溝 岳彦 順天堂大学, 医学(系)研究科(研究院), 教授 (60302840) ; 岡村 康司 大阪大学, 医学系研究科, 教授 (80201987) ; 杉本 幸彦 熊本大学, 大学院生命科学研究部(薬), 教授 (80243038)
• Project Period (FY): 2015-06-29 – 2020-03-31
• Project Status: Completed (Fiscal Year 2019)
• Budget Amount: ¥260,650,000 (Direct Cost: ¥200,500,000、Indirect Cost: ¥60,150,000); Fiscal Year 2019: ¥40,170,000 (Direct Cost: ¥30,900,000、Indirect Cost: ¥9,270,000); Fiscal Year 2018: ¥36,530,000 (Direct Cost: ¥28,100,000、Indirect Cost: ¥8,430,000); Fiscal Year 2017: ¥38,610,000 (Direct Cost: ¥29,700,000、Indirect Cost: ¥8,910,000); Fiscal Year 2016: ¥34,320,000 (Direct Cost: ¥26,400,000、Indirect Cost: ¥7,920,000); Fiscal Year 2015: ¥111,020,000 (Direct Cost: ¥85,400,000、Indirect Cost: ¥25,620,000)
• Keywords: 研究支援センター / 領域事務局 / 脂質データベース / 広報活動 / 脂質 / 領域マネジメント / 領域会議の開催

Outline of Final Research Achievements

To understand the importance of Lipid Quality (LipoQuality) in biological systems, we developed a steering group including 5 research support centers that help to promote the LipoQuality program project efficiently by sharing methods, technologies and resources for all members including those who had little experience in lipid biology research. Especially the advanced lipidomics platform played important roles by developing the cutting-edge analytical technologies and bioinformatics to accelerate the whole program. Moreover, we organized annual project meetings, homepage, lipid database, newsletters, international symposia, workshop for young scientists, to prevail our research concept and achievements of this program project.

Academic Significance and Societal Importance of the Research Achievements

脂質分子の質的違い（リポクオリティの違い）に注目する研究は黎明期にあり、世界的に見ても個々の研究者が個別の研究を進めている状況であった。本総括班の形成によりもたらされた成果は、脂質の構造多様性を読み解くための革新的な分析・可視化技術を軸に、脂質分子種の多様性の生物学的意義についての学術的理解を与え、次世代のライフイノベーション研究に独創的な波及効果をもたらすことが期待される。

Research Products

• [Int'l Joint Research] Rockfeller University/Columbia University/Icahn School of Medicine at Mount Sinai(米国)
• [Int'l Joint Research] University of Cambridge/University of Edinburgh/Babraham Institute(英国)
• [Int'l Joint Research] University of Toronto(カナダ)
• [Int'l Joint Research] National University of Singapore(シンガポール)
• [Int'l Joint Research] Friedrich-Schiller-University Jena(ドイツ)
• [Int'l Joint Research]
• [Int'l Joint Research] National University of Singapore(シンガポール)
• [Int'l Joint Research] Harvard Medical School/Univ. of California Davis/Johns Hopkins University(米国)
• [Int'l Joint Research] Laval University(カナダ)
• [Int'l Joint Research] Imperial College London/Babraham Institute(英国)
• [Int'l Joint Research] Mahidol University(タイ)
• [Int'l Joint Research]
• [Int'l Joint Research] Harvard Medical School/Univ. of California Davis/Johns Hopkins Univ. School of Med.(USA)
• [Int'l Joint Research] Shanghai Jiao Tong University(中国)
• [Int'l Joint Research] Babraham Institute/Imperial College London(UK)
• [Int'l Joint Research] チェコ科学アカデミー(チェコ)
• [Int'l Joint Research] Univ. Groningen(Netherlands)
• [Int'l Joint Research] Harvard Medical School/Univ. of California Davis/UC Irvine(USA)
• [Int'l Joint Research] University College London/Babraham Institute/Imperial College London(UK)
• [Int'l Joint Research] IMBA(Austria)
• [Int'l Joint Research] Institute of Molecular Genetics, ASCR(Czech Republic)
• [Int'l Joint Research] University of Lyon/Claude Bernard Lyon 1 University(France)
• [Int'l Joint Research]
• [Int'l Joint Research] Univ. of Colorado/Mayo Clinic Alizona,/Harvard Medical School(USA)
• [Int'l Joint Research] University College London/Cambridge/Babraham Inst(ＵＫ)
• [Int'l Joint Research] Univ. of Monash/Women's & Children's Hospital(Australia)
• [Int'l Joint Research] I2MC, I.G.B.M.C./Institut Pasteur de Lille(France)
• [Int'l Joint Research] Università degli Studi di Torino/University of Milan/Università degli Studi di Milano(Italy)
• [Int'l Joint Research]
• [Journal Article] Lipidomics links oxidized phosphatidylcholines and coronary arteritis in Kawasaki disease (2021)
  • Author(s): Nakashima Y, Sakai Y, Mizuno Y, Furuno K, Hirono K, Takatsuki S, Suzuki H, Onouchi Y, Kobayashi T, Tanabe K, Hamase K, Miyamoto T, Aoyagi R, Arita M, Yamamura K, Tanaka T, Nishio H, Takada H, Ohga S, Hara T.
  • Journal Title: Cardiovasc Res Volume: - Pages: 0-0
  • DOI: 10.1093/cvr/cvz305
  • Peer Reviewed / Open Access
• [Journal Article] Cysteinyl leukotriene metabolism of human eosinophils in allergic disease (2020)
  • Author(s): Miyata Jun、Fukunaga Koichi、Kawashima Yusuke、Ohara Osamu、Arita Makoto
  • Journal Title: Allergol. Int. Volume: 69 Issue: 1 Pages: 28-34
  • DOI: 10.1016/j.alit.2019.06.002
  • ISSN: 1323-8930, 1440-1592
  • Peer Reviewed / Open Access
• [Journal Article] Homeostatic Function of Dermokine in the Skin Barrier and Inflammation. (2020)
  • Author(s): Akira Utsunomiya, Takenao Chino, Natsuko Utsunomiya, Vu Huy Luong, Atsushi Tokuriki, Tatsuro Naganuma, Makoto Arita, Kiyoshi Higashi, Koichi Saito, Noriyuki Suzuki, Ayako Ohara, Manabu Sugai, Koji Sugawara, Daisuke Tsuruta, Noritaka Oyama, Minoru Hasegawa
  • Journal Title: J Invest Dermatol Volume: 140 Pages: 838-849
  • DOI: 10.1016/j.jid.2019.09.011
  • Peer Reviewed
• [Journal Article] A lipidome atlas in MS-DIAL 4. (2020)
  • Author(s): Tsugawa H, Ikeda K, Takahashi M, Satoh A, Mori Y, Uchino H, Okahashi N, Yamada Y, Tada I, Bonini P, Higashi Y, Okazaki Y, Zhou Z, Zhu Z, Koelmel J, Cajka T, Fiehn O, Saito K, Arita M, Arita M.
  • Journal Title: Nature Biotechnology Volume: in press
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice (2020)
  • Author(s): Kimura I, Miyamoto J, Ohue-Kitano R, Watanabe K, Yamada T, Onuki M, Aoki R, Isobe Y, Kashihara D, Inoue D, Inaba A, Takamura Y, Taira S, Kumaki S, Watanabe M, Ito M, Nakagawa F, Irie J, Kakuta H, Shinohara M, Iwatsuki K, Tsujimoto G, Ohno H, Arita M, Itoh H, Hase K.
  • Journal Title: Science Volume: 367 Pages: 6481-6481
  • DOI: 10.1126/science.aaw8429
  • Peer Reviewed / Open Access
• [Journal Article] Synthesis of Phosphatidylcholines Possessing Functionalized Acids at sn-2, and 13C-14N and 13C-31P Couplings in Their 13C NMR Spectra (2020)
  • Author(s): Morita Masao、Saito Shun、Shinohara Riku、Aoyagi Ryohei、Arita Makoto、Kobayashi Yuichi
  • Journal Title: Synlett Volume: 31 Pages: 718-722
  • DOI: 10.1055/s-0039-1691584
  • Peer Reviewed
• [Journal Article] Maternal ω3 Docosapentaenoic Acid Inhibits Infant Allergic Dermatitis Through TRAIL-expressing Plasmacytoid Dendritic Cells in Mice (2020)
  • Author(s): Hirata SI, Nagatake T, Sawane K, Hosomi K, Honda T, Ono S, Shibuya N, Saito E, Adachi J, Abe Y, Isoyama J, Suzuki H, Matsunaga A, Tomonaga T, Kiyono H, Kabashima K, Arita M, Kunisawa J.
  • Journal Title: Allergy Volume: in press Pages: 0-0
  • DOI: 10.1111/all.14217
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Prostaglandin E2 and its receptor EP2 trigger signaling that contributes to YAP-mediated cell competition. (2020)
  • Author(s): Ishihara E, Nagaoka Y, Okuno T, Kofuji S, Ishigami-Yuasa M, Kagechika H, Kamimura K, Terai S, Yokomizo T, Sugimoto Y, Fujita Y, Suzuki A, Nishina H.
  • Journal Title: FASEB J Volume: 25(3) Pages: 14528-14541
  • DOI: 10.1111/gtc.12750
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Induced Prostanoid Synthesis Regulates the Balance between Th1- and Th2-Producing Inflammatory Cytokines in the Thymus of Diet-Restricted Mice (2020)
  • Author(s): Razali N, Hohjoh H, Inazumi T, Maharjan BD, Nakagawa K, Konishi M, Sugimoto Y, Hasegawa H.
  • Journal Title: Biol. Pharm. Bull. Volume: 43 Issue: 4 Pages: 649-662
  • DOI: 10.1248/bpb.b19-00838
  • ISSN: 0918-6158, 1347-5215
  • Peer Reviewed
• [Journal Article] Effects of the selective EP2 receptor agonist omidenepag on adipocyte differentiation in 3T3-L1 cells (2020)
  • Author(s): Yamamoto Y, Taniguchi T, Inazumi T, Iwamura R, Yoneda K, Odani-Kawabata N, Matsugi T, Sugimoto Y, Shams NK.
  • Journal Title: J. Ocul. Pharmacol. Ther. Volume: 36 Pages: 162-169
  • DOI: 10.1089/jop.2019.0079
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] プロスタグランジンD2レセプターのシグナル伝達 (2020)
  • Author(s): 稲住知明, 杉本幸彦
  • Journal Title: 臨床免疫・アレルギー科（科学評論社） Volume: 73 (13) Pages: 58-63
• [Journal Article] Secreted phospholipase PLA2G2D contributes to metabolic health by mobilizing omega3 polyunsaturated fatty acids in WAT (2020)
  • Author(s): Sato H, Taketomi Y, Miki Y, Murase R, Yamamoto K, Murakami M.
  • Journal Title: Cell Reports Volume: in press Pages: 0-0
  • Peer Reviewed / Open Access
• [Journal Article] Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress (2020)
  • Author(s): Fujihira Haruhiko、Masahara-Negishi Yuki、Akimoto Yoshihiro、Hirayama Hiroto、Lee Hyeon-Cheol、Story Benjamin A.、Mueller William F.、Jakob Petra、Clauder-M?nster Sandra、Steinmetz Lars M.、Radhakrishnan Senthil K.、Kawakami Hayato、Kamada Yoshihiro、Miyoshi Eiji、Yokomizo Takehiko、Suzuki Tadashi
  • Journal Title: Biochim. Biophys. Acta Mol. Basis Dis. Volume: 1866 Pages: 165588-165588
  • DOI: 10.1016/j.bbadis.2019.165588
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Loss of autophagy impairs physiological steatosis by accumulation of NCoR1. (2020)
  • Author(s): Takahashi SS, Sou YS, Saito T, Kuma A, Yabe T, Sugiura Y, Lee HC, Suematsu M, Yokomizo T, Koike M, Terai S, Mizushima N, Waguri S, Komatsu M.
  • Journal Title: Life Sci Alliance. Volume: 3 Pages: 201900513-201900513
  • DOI: 10.26508/lsa.201900513
  • Peer Reviewed / Open Access
• [Journal Article] n-3 Fatty Acid and Its Metabolite 18-HEPE Ameliorate Retinal Neuronal Cell Dysfunction by Enhancing M?ller BDNF in Diabetic Retinopathy (2020)
  • Author(s): Suzumura Ayana、Kaneko Hiroki、Funahashi Yasuhito、Takayama Kei、Nagaya Masatoshi、Ito Seina、Okuno Toshiaki、Hirakata Toshiaki、Nonobe Norie、Kataoka Keiko、Shimizu Hideyuki、Namba Rina、Yamada Kazuhisa、Ye Fuxiang、Ozawa Yoko、Yokomizo Takehiko、Terasaki Hiroko
  • Journal Title: Diabetes Volume: 69 Pages: 724-735
  • DOI: 10.2337/db19-0550
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The role of propofol hydroxyl group in 5-lipoxygenase recognition (2020)
  • Author(s): Yuki Koichi、Bu Weiming、Eckenhoff Roderic G.、Yokomizo Takehiko、Okuno Toshiaki
  • Journal Title: Biochem Biophys Res Commun. Volume: In press Pages: 909-914
  • DOI: 10.1016/j.bbrc.2020.03.037
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Leukotriene B4 receptor type 2 (BLT2) accelerates the healing of intestinal lesions by promoting epithelial cell proliferation (2020)
  • Author(s): Matsumoto Y, Matsuya Y, Kano N, Amagase K, Saeki K, Matsumoto K, Yokomizo T, Kato S
  • Journal Title: J Pharmacol Exp Ther Volume: 373 Pages: 1-9
  • DOI: 10.1124/jpet.119.263145
  • Peer Reviewed
• [Journal Article] Aging exacerbates high‐fat diet‐induced steatohepatitis through alteration in hepatic lipid metabolism in mice (2020)
  • Author(s): Ishizuka Kei、Kon Kazuyoshi、Lee‐Okada Hyeon‐Cheol、Arai Kumiko、Uchiyama Akira、Yamashina Shunhei、Yokomizo Takehiko、Ikejima Kenichi
  • Journal Title: journal of gastroenterology and hepatology Volume: In press Pages: 1437-1448
  • DOI: 10.1111/jgh.15006
  • Peer Reviewed
• [Journal Article] ESCRT machinery mediates selective microautophagy of endoplasmic reticulum. (2020)
  • Author(s): Schafer J, Schessner JP, Tsuju T, Funaya C, Bircham PW, Schaeff K, Ruffini G, Fujimoto T, Schuck S.
  • Journal Title: EMBO J Volume: 39
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Possible involvement of PS-PLA1 and lysophosphatidylserine receptor (LPS1) in hepatocellular carcinoma. (2020)
  • Author(s): Uranbileg B, Kurano M, Sato M, Ikeda H, Ishizawa T, Hasegawa K, Kokudo N, Yatomi Y.
  • Journal Title: Scientific Reports Volume: 10 Pages: 2659-2659
  • DOI: 10.1038/s41598-020-59590-3
  • Peer Reviewed / Open Access
• [Journal Article] Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism. (2020)
  • Author(s): Nakawatari K, Kurano M, Araki O, Nishikawa M, Shimamoto S, Igarashi K, Aoki J, Murakami M, Yatomi Y.
  • Journal Title: Clinica Chimica Acta Volume: 503 Pages: 99-106
  • DOI: 10.1016/j.cca.2020.01.011
  • Peer Reviewed
• [Journal Article] Protection Against Insulin Resistance by Apolipoprotein M/Sphingosine-1-Phosphate. (2020)
  • Author(s): Kurano M, Tsukamoto K, Shimizu T, Kassai H, Nakao K, Aiba A, Hara M, Yatomi Y.
  • Journal Title: Diabetes Volume: 69 Pages: 867-881
  • DOI: 10.2337/db19-0811
  • Peer Reviewed
• [Journal Article] Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model. (2020)
  • Author(s): Uranbileg B, Ito N, Kurano M, Saigusa D, Saito R, Uruno A, Kano K, Ikeda H, Yamada Y, Sumitani M, Sekiguchi M, Aoki J, Yatomi Y.
  • Journal Title: Sci Rep Volume: 9 Pages: 16578-16578
  • DOI: 10.1038/s41598-019-52999-5
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of urinary sphingolipids using liquid chromatography-tandem mass spectrometry in diabetic nephropathy. (2020)
  • Author(s): Morita Y, Kurano M, Sakai E, Nishikawa T, Nishikawa M, Sawabe M, Aoki J, Yatomi Y.
  • Journal Title: Journal of Diabetes Investigation Volume: 11 Pages: 441-449
  • DOI: 10.1111/jdi.13154
  • Peer Reviewed / Open Access
• [Journal Article] Tenascin C in the Tumor-Nerve Microenvironment Enhances Perineural Invasion and Correlates With Locoregional Recurrence in Pancreatic Ductal Adenocarcinoma. (2020)
  • Author(s): Furuhashi S, Sakaguchi T, Murakami T, Fukushima M, Morita Y, Ikegami K, Kikuchi H, Setou M, Takeuchi H.
  • Journal Title: Pancreas Volume: 49 Pages: 442-454
  • DOI: 10.1097/mpa.0000000000001506
  • Peer Reviewed
• [Journal Article] Engineering an enhanced voltage-sensing phosphatase (2020)
  • Author(s): Kawanabe Akira、Mizutani Natsuki、Polat Onur K.、Yonezawa Tomoko、Kawai Takafumi、Mori Masayuki X.、Okamura Yasushi
  • Journal Title: Journal of General Physiology Volume: 152
  • DOI: 10.1085/jgp.201912491
  • Peer Reviewed
• [Journal Article] A common signaling pathway leading to degranulation in mast cells and its regulation by CCR1 ligand. (2020)
  • Author(s): Chang HW, Kanegasaki S, Jin F, Deng Y, You Z, Chang JH, Kim DY, Timilshina M, Kim JR, Lee YJ, Toyama-Sorimachi N, Tsuchiya T.
  • Journal Title: Allergy Volume: in press Pages: 0-0
  • DOI: 10.1111/all.14186
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Soluble SLAMF7 Promotes the Growth of Myeloma Cells via Homophilic Interaction with Surface SLAMF7. (2020)
  • Author(s): Kikuchi J, Hori M, Iha H, Toyama-Sorimachi N, Hagiwara S, Kuroda Y, Koyama D, Izumi T, Yasui H, Suzuki A, Furukawa Y.
  • Journal Title: Leukemia Volume: 34 Pages: 180-195
  • DOI: 10.1038/s41375-019-0525-6
  • Peer Reviewed / Open Access
• [Journal Article] リポクオリティの違いを捉えるノンターゲット脂質解析 (2019)
  • Author(s): 内野春希、津川裕司、有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1238-1244
• [Journal Article] アレルギー疾患における好酸球の脂肪酸代謝異常 (2019)
  • Author(s): 宮田純、福永興壱、有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1008-1014
• [Journal Article] ω３脂肪酸クオリティによる疾患制御 (2019)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 967-970
• [Journal Article] 脂質クオリティ研究の基礎と臨床（企画・編集） (2019)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269
• [Journal Article] 腸内細菌のリポクオリティと生体制御 (2019)
  • Author(s): 安田柊、岡橋伸幸、上田政宏、有田誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: 393-399
• [Journal Article] 脂肪酸クオリティによる炎症の制御 (2019)
  • Author(s): 有田誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: 355-361
• [Journal Article] 生体制御にかかわる多彩なリポクオリティ 基礎から病態まで（企画・編集） (2019)
  • Author(s): 有田誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30
• [Journal Article] Omega-3 fatty acid-derived mediators that control inflammation and tissue homeostasis (2019)
  • Author(s): Ishihara Tomoaki、Yoshida Mio、Arita Makoto
  • Journal Title: Int Immunol Volume: - Pages: 559-567
  • DOI: 10.1093/intimm/dxz001
  • Peer Reviewed / Open Access
• [Journal Article] Lipidomics needs more standardization (2019)
  • Author(s): Lipidomics Standards Initiative Consortium
  • Journal Title: Nature Metabolism Volume: 1 Pages: 745-747
  • DOI: 10.1038/s42255-019-0094-z
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Mass Spectrometry Data Repository Enhances Novel Metabolite Discoveries with Advances in Computational Metabolomics (2019)
  • Author(s): Tsugawa Hiroshi、Satoh Aya、Uchino Haruki、Cajka Tomas、Arita Makoto、Arita Masanori
  • Journal Title: Metabolites Volume: 9 Pages: 119-119
  • DOI: 10.3390/metabo9060119
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Dysregulated fatty acid metabolism in nasal polyp-derived eosinophils from patients with chronic rhinosinusitis (2019)
  • Author(s): Miyata Jun、Fukunaga Koichi、Kawashima Yusuke、Watanabe Takashi、Saitoh Akina、Hirosaki Tomomi、Araki Yasutomo、Kikawada Toru、Betsuyaku Tomoko、Ohara Osamu、Arita Makoto
  • Journal Title: Allergy Volume: 74 Pages: 1113-1124
  • DOI: 10.1111/all.13726
  • Peer Reviewed
• [Journal Article] Preferential Incorporation of Administered Eicosapentaenoic Acid Into Thin-Cap Atherosclerotic Plaques (2019)
  • Author(s): Sato Tomohito、Horikawa Makoto、Takei Shiro、Yamazaki Fumiyoshi、Ito Takashi K.、Kondo Takeshi、Sakurai Takanobu、Kahyo Tomoaki、Ikegami Koji、Sato Shumpei、Sato Ryota、Jinno Yasutaka、Kawano Hiroyuki、Naoe Satoko、Arita Makoto、Kashiwagi Yukiyasu、Setou Mitsutoshi
  • Journal Title: Arterioscler Thromb Vasc Biol Volume: 39 Pages: 1802-1816
  • DOI: 10.1161/atvbaha.119.313093
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Gut microbiota confers host resistance to obesity by metabolizing dietary polyunsaturated fatty acids (2019)
  • Author(s): Miyamoto J, Igarashi M, Watanabe K, Karaki SI, Mukouyama H, Kishino S, Li X, Ichimura A, Irie J, Sugimoto Y, Mizutani T, Sugawara T, Miki T, Ogawa J, Drucker DJ, Arita M, Itoh H, Kimura I
  • Journal Title: Nat Commun. Volume: 10 Pages: 1-15
  • DOI: 10.1038/s41467-019-11978-0
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Characterization of Lipid Profiles after Dietary Intake of Polyunsaturated Fatty Acids Using Integrated Untargeted and Targeted Lipidomics (2019)
  • Author(s): Naoe Satoko、Tsugawa Hiroshi、Takahashi Mikiko、Ikeda Kazutaka、Arita Makoto
  • Journal Title: Metabolites Volume: 9 Pages: 241-241
  • DOI: 10.3390/metabo9100241
  • Peer Reviewed / Open Access
• [Journal Article] Dietary omega-3 fatty acid dampens allergic rhinitis via eosinophilic production of the anti-allergic lipid mediator 15-hydroxyeicosapentaenoic acid in mice (2019)
  • Author(s): Sawane K, Nagatake T, Hosomi K, Hirata SI, Adachi J, Abe Y, Isoyama J, Suzuki H, Matsunaga A, Fukumitsu S, Aida K, Tomonaga T, Arita M, and Kunisawa J
  • Journal Title: Nutrients Volume: 11 Pages: 2868-2868
  • DOI: 10.3390/nu11122868
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Acyl-CoA synthetase 6 regulates long-chain polyunsaturated fatty acid composition of membrane phospholipids in spermatids and supports normal spermatogenic processes in mice (2019)
  • Author(s): Shishikura Kyosuke、Kuroha Sayoko、Matsueda Shinnosuke、Iseki Hachiro、Matsui Takeshi、Inoue Azusa、Arita Makoto
  • Journal Title: FASEB J Volume: 33 Pages: 14194-14203
  • DOI: 10.1096/fj.201901074r
  • Peer Reviewed / Open Access
• [Journal Article] Ligand binding to human prostaglandin E receptor EP4 at the lipid-bilayer interface (2019)
  • Author(s): Toyoda Y, Morimoto K, Suno R, et al.
  • Journal Title: Nature chemical biology Volume: 15 Pages: 18-26
  • DOI: 10.1038/s41589-018-0131-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche (2019)
  • Author(s): Kitadate Y., Jorg DJ., Tokue M,. Maruyama A., Ishikawa R., Tsuchiya S., Segi-Nishida E., Nakagawa T., Uchida A., Kimura-Yoshida C., Mizuno S., Sugiyama F., Azami T., Ema M., Noda C., Kobayashi S., Matsuo I., Kanai Y., Nagasawa T., Sugimoto Y., Takahashi S., Simons BD., Yoshida S.
  • Journal Title: Cell Stem Cell. Volume: 24 Pages: 1-2
  • DOI: 10.1016/j.stem.2018.11.013
  • NAID: 120006583050
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming (2019)
  • Author(s): Muraoka Naoto、Nara Kaori、Tamura Fumiya、Kojima Hidenori、Yamakawa Hiroyuki、Sadahiro Taketaro、Miyamoto Kazutaka、Isomi Mari、Haginiwa Sho、Tani Hidenori、Kurotsu Shota、Osakabe Rina、Torii Satoru、Shimizu Shigeomi、Okano Hideyuki、Sugimoto Yukihiko、Fukuda Keiichi、Ieda Masaki
  • Journal Title: Nature Communications Volume: 10 Pages: 1-15
  • DOI: 10.1038/s41467-019-08626-y
  • Peer Reviewed / Open Access
• [Journal Article] Essential role of prostaglandin E2 and the EP3 receptor in lymphatic vessel development during zebrafish embryogenesis (2019)
  • Author(s): Iwasaki R, Tsuge K, Kishimoto K, Hayashi Y, Iwaana T, Hohjoh H, Inazumi T, Kawahara A, Tsuchiya S, Sugimoto Y.
  • Journal Title: Sci. Rep. Volume: 9 Pages: 7650-7650
  • DOI: 10.1038/s41598-019-44095-5
  • Peer Reviewed / Open Access
• [Journal Article] Molecular mechanisms underlying prostaglandin E2-exacerbated inflammation and immune diseases. (2019)
  • Author(s): Tsuge K, Inazumi T, Shimamoto A, Sugimoto Y
  • Journal Title: International immunology Volume: － Pages: 1-10
  • DOI: 10.1093/intimm/dxz021
  • Peer Reviewed / Open Access
• [Journal Article] Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis. (2019)
  • Author(s): Sakurai K, Dainichi T, Garcet S, Tsuchiya S, Yamamoto Y, Kitoh A, Honda T, Nomura T, Egawa G, Otsuka A, Nakajima S, Matsumoto R, Nakano Y, Otsuka M, Iwakura Y, Grinberg-Bleyer Y, Ghosh S, Sugimoto Y, Guttman-Yassky E, Krueger JG, Kabashima K.
  • Journal Title: J Allergy Clin Immunol. Volume: 144(4) Pages: 1036-1049
  • DOI: 10.1016/j.jaci.2019.06.019
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Functional Hierarchy of Uterotonics Required for Successful Parturition in Mice (2019)
  • Author(s): Yoshida M, Takayanagi Y, Ichino-Yamashita A, Sato K, Sugimoto Y, Kimura T, Nishimori K.
  • Journal Title: Endocrinology Volume: 160 Pages: 2800-2810
  • DOI: 10.1210/en.2019-00499
  • Peer Reviewed / Open Access
• [Journal Article] シクロオキシゲナーゼ経路によるリポクオリティ認識 (2019)
  • Author(s): 稲住知明, 杉本幸彦
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 (1) Pages: 1002-1007
• [Journal Article] Novel functions of Phospholipase A2s: Overview. (2019)
  • Author(s): Murakami M.
  • Journal Title: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Volume: 1864 Pages: 763-765
  • DOI: 10.1016/j.bbalip.2019.02.005
  • Peer Reviewed
• [Journal Article] Group IID, IIE, IIF and III secreted phospholipase A2s. (2019)
  • Author(s): Murakami M, Miki Y, Sato H, Murase R, Taketomi Y, Yamamoto K.
  • Journal Title: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Volume: 1864 Pages: 803-818
  • DOI: 10.1016/j.bbalip.2018.08.014
  • Peer Reviewed / Open Access
• [Journal Article] The role of PNPLA1 in ω-O-acylceramide synthesis and skin barrier function (2019)
  • Author(s): Hirabayashi Tetsuya、Murakami Makoto、Kihara Akio
  • Journal Title: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids Volume: 1864 Pages: 803-818
  • DOI: 10.1016/j.bbalip.2018.09.010
  • Peer Reviewed / Open Access
• [Journal Article] Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling. (2019)
  • Author(s): Mori A, Hatano T, Inoshita T, Shiba-Fukushima K, Koinuma T, Meng H, Kubo SI, Spratt S, Cui C, Yamashita C, Miki Y, Yamamoto K, Hirabayashi T, Murakami M, Takahashi Y, Shindou H, Nonaka T, Hasegawa M, Okuzumi A, Imai Y, Hattori N.
  • Journal Title: Proc. Natl. Acad. Sci. USA. Volume: 116(41) Pages: 20689-20699
  • DOI: 10.1073/pnas.1902958116
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The orphan nuclear receptor NR4A1 promotes FcepsilonRI-stimulated mast cell activation and anaphylaxis by counteracting the inhibitory LKB1/AMPK axis. (2019)
  • Author(s): Jin F, Li X. Deng Y, Timilshina M. Huang B, Kim DY, Chang JH, Ichinose H, Baek SH, Murakami M, Lee YJ, Chang HW
  • Journal Title: Allergy Volume: 74 Pages: 1145-1156
  • DOI: 10.1111/all.13702
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 脂質メディエーターとイムノメタボリズム (2019)
  • Author(s): 佐藤弘泰、村上誠
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 (2) Pages: 61-71
• [Journal Article] 脂質メディエーターが繋ぐ臓器連関と動的恒常性 (2019)
  • Author(s): 村上誠
  • Journal Title: 実験医学（羊土社） Volume: 37 (7) Pages: 149-155
• [Journal Article] 脂質メディエーターとアレルギー (2019)
  • Author(s): 武富芳隆、村上誠
  • Journal Title: 実験医学（羊土社） Volume: 37 (10) Pages: 88-95
• [Journal Article] ホスホリパーゼA2 による代謝と疾患の制御 (2019)
  • Author(s): 村上誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 (13) Pages: 1024-1028
• [Journal Article] リピドミクスから見えてきた酸化脂肪酸によるマスト細胞の制御機構 (2019)
  • Author(s): 嶋中雄太、村上誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 270 (5) Pages: 401-407
• [Journal Article] Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice (2019)
  • Author(s): Kamata Mariko、Amano Hideki、Ito Yoshiya、Fujita Tomoe、Otaka Fumisato、Hosono Kanako、Kamata Kouju、Takeuchi Yasuo、Yokomizo Takehiko、Shimizu Takao、Majima Masataka
  • Journal Title: PLoS One Volume: 14 Pages: 202842-202842
  • DOI: 10.1371/journal.pone.0202842
  • Peer Reviewed / Open Access
• [Journal Article] Papaverine identified as an inhibitor of high mobility group box 1/receptor for advanced glycation end-products interaction suppresses high mobility group box 1-mediated inflammatory responses. (2019)
  • Author(s): Tamada K, Nakajima S, Ogawa N, Inada M, Shibasaki H, Sato A, Takasawa R, Yoshimori A, Suzuki Y, Watanabe N, Oyama T, Abe H, Inoue S, Abe T, Yokomizo T, Tanuma S.
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 511 Pages: 665-670
  • DOI: 10.1016/j.bbrc.2019.01.136
  • Peer Reviewed / Open Access
• [Journal Article] Cyclooxygenase inhibition in mice heightens adaptive‐ and innate‐type responses against inhaled protease allergen and IL ‐33 (2019)
  • Author(s): Maruyama Natsuko、Takai Toshiro、Kamijo Seiji、Suchiva Punyada、Ohba Mai、Takeshige Tomohito、Suzuki Mayu、Hara Mutsuko、Matsuno Kei、Harada Sonoko、Harada Norihiro、Nakae Susumu、Sudo Katsuko、Okuno Toshiaki、Yokomizo Takehiko、Ogawa Hideoki、Okumura Ko、Ikeda Shigaku
  • Journal Title: Allergy. Volume: 印刷中 Pages: 2237-2240
  • DOI: 10.1111/all.13831
  • Peer Reviewed / Open Access
• [Journal Article] BLT1 Mediates Commensal Bacteria-Dependent Innate Immune Signals to Enhance Antigen-Specific Intestinal IgA Responses (2019)
  • Author(s): Nagatake T, Hirata SI, Koga T, Kuroda E, Kobari S, Suzuki H, Hosomi K, Matsumoto N, Yanrismet Y, Shimojou M, Morimoto S, Sasaki F, Ishii KJ, Yokomizo T, Kunisawa J.
  • Journal Title: Mucosal Immunol Volume: 12 Pages: 1082-1082
  • DOI: 10.1038/s41385-019-0175-z
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] An Alternative Pathway to Leukotriene B4 Enantiomers Involving a 1,8-Diol-Forming Reaction of an Algal Oxylipin. (2019)
  • Author(s): Jagusch H., Werner M., Okuno T., Yokomizo T., Werz O., Pohnert G.
  • Journal Title: Organic Letters Volume: 21 Pages: 4667-4670
  • DOI: 10.1021/acs.orglett.9b01554
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dietary supplementation of omega-3 fatty acid eicosapentaenoic acid does not ameliorate pruritus in murine models of atopic dermatitis and psoriasis. (2019)
  • Author(s): Lee H. C., Tominaga M., Yasukawa K., Ohba M., Takahashi N., Honda K., Okuno T., Takamori K., Yokomizo T.
  • Journal Title: Journal of Dermatological Science Volume: 95 Pages: 130-133
  • DOI: 10.1016/j.jdermsci.2019.07.010
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction. (2019)
  • Author(s): Koutsogiannaki S., Hou L., Babazada H., Okuno T., Blazon-Brown N., Soriano S. G., Yokomizo T., Yuki K.
  • Journal Title: The FASEB Journal Volume: 33 Pages: 12668-12679
  • DOI: 10.1096/fj.201901360r
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system. (2019)
  • Author(s): Okuno T., Koutsogiannaki S., Hou L., Bu W., Ohto U., Eckenhoff R. G., Yokomizo T., Yuki K.
  • Journal Title: The FASEB Journal Volume: 33 Pages: 14528-14541
  • DOI: 10.1096/fj.201901570r
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Sensitization of Gastric Cancer Cells to Irinotecan by p53 Activation. (2019)
  • Author(s): Zhang, S Kohira, Y Oerita, S Ishimine, M Kobayashi, T Chua, S M B Nakaoka, H Inoue, I Hino, O Yokomizo, T Fukunaga, T H.C., L-O
  • Journal Title: BPB Rep Volume: 2 Pages: 130-133
• [Journal Article] ロイコトリエンB4第1受容体は滲出型加齢黄斑変性症の新規治療標的となる (2019)
  • Author(s): 佐々木文之 横溝岳彦
  • Journal Title: 実験医学 Volume: 37 Pages: 411-414
• [Journal Article] Lysophosphatidylinositol‐acyltransferase‐1 is involved in cytosolic Ca2+ oscillations in macrophages (2019)
  • Author(s): Takemasu Shinya、Ito Masaki、Morioka Shin、Nigorikawa Kiyomi、Kofuji Satoshi、Takasuga Shunsuke、Eguchi Satoshi、Nakanishi Hiroki、Matsuoka Isao、Sasaki Junko、Sasaki Takehiko、Hazeki Kaoru
  • Journal Title: Genes to cells Volume: - Pages: 1-11
  • DOI: 10.1111/gtc.12681
  • Peer Reviewed / Open Access
• [Journal Article] A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites (2019)
  • Author(s): McCormick Barry, Craig Helen E., Chu Julia Y., Carlin Leo M., Canel Marta, Wollweber Florian, Toivakka Matilda, Michael Melina, Astier Anne L., Norton Laura, Lilja Johanna, Felton Jennifer M., Sasaki Takehiko, Ivaska Johanna, Hers Ingeborg, Dransfield Ian, Rossi Adriano G., Vermeren Sonja
  • Journal Title: JOURNAL OF IMMUNOLOGY Volume: 203 Pages: 1579-1588
  • DOI: 10.4049/jimmunol.1900443
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency (2019)
  • Author(s): Nishio Miki、Miyachi Yousuke、Otani Junji、Tane Shoji、Omori Hirofumi、Ueda Fumihito、Togashi Hideru、Sasaki Takehiko、Mak Tak Wah、Nakao Kazuwa、Fujita Yasuyuki、Nishina Hiroshi、Maehama Tomohiko、Suzuki Akira
  • Journal Title: FASEB JOURNAL Volume: 33 Pages: 5548-5560
  • DOI: 10.1096/fj.201802005r
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A Peptide Derived from Phosphoinositide 3-kinase Inhibits Endocytosis and Influenza Virus Infection (2019)
  • Author(s): Fujioka Y, Satoh AO, Horiuchi K, Fujioka M, Tsutsumi K, Sasaki J, Nepal P, Kashiwagi S, Paudel S, Nishide S, Nanbo A, Sasaki T, Ohba Y
  • Journal Title: Cell Struct. Funct. Volume: 印刷中 Issue: 1 Pages: 61-74
  • DOI: 10.1247/csf.19001
  • NAID: 130007636814
  • ISSN: 0386-7196, 1347-3700
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Increased fatty acyl saturation of phosphatidylinositol phosphates in prostate cancer progression. (2019)
  • Author(s): Koizumi A, Narita S, Nakanishi H, Ishikawa M, Eguchi S, Kimura H, Takasuga S, Huang M, Inoue T, Sasaki J, Yoshioka T, Habuchi T, Sasaki T.
  • Journal Title: Sci Rep. Volume: 9 Pages: 13257-13257
  • DOI: 10.1038/s41598-019-49744-3
  • Peer Reviewed / Open Access
• [Journal Article] Polarized PtdIns(4,5)P2distribution mediated by a voltage-sensing phosphatase (VSP) regulates sperm motility (2019)
  • Author(s): Kawai Takafumi、Miyata Haruhiko、Nakanishi Hiroki、Sakata Souhei、Morioka Shin、Sasaki Junko、Watanabe Masahiko、Sakimura Kenji、Fujimoto Toyoshi、Sasaki Takehiko、Ikawa Masahito、Okamura Yasushi
  • Journal Title: Proceedings of the National Academy of Sciences of the United States of America Volume: 116 Pages: 26020-26026
  • DOI: 10.1073/pnas.1916867116
  • Peer Reviewed / Open Access
• [Journal Article] 細胞膜での蛋白質-イノシトールリン脂質相互作用へのアシル基の関与 (2019)
  • Author(s): 佐々木雄彦, 山本詠士, 佐々木純子
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1068-1072
• [Journal Article] Predominant localization of phosphatidylserine at the cytoplasmic leaflet of the ER, and its TMEM16K-dependent redistribution (2019)
  • Author(s): Tsuji Takuma、Cheng Jinglei、Tatematsu Tsuyako、Ebata Aoi、Kamikawa Hiroki、Fujita Akikazu、Gyobu Sayuri、Segawa Katsumori、Arai Hiroyuki、Taguchi Tomohiko、Nagata Shigekazu、Fujimoto Toyoshi
  • Journal Title: Proc Natl Acad Sci U S A Volume: 116 Pages: 13368-13373
  • DOI: 10.1073/pnas.1822025116
  • Peer Reviewed / Open Access
• [Journal Article] ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma (2019)
  • Author(s): Yamaguchi T, Hayashi M, Ida L, Yamamoto M, Lu C, Kajino T, Cheng J, Nakatochi M, Isomura H, Yamazaki M, Suzuki M, Fujimoto T, Takahashi T.
  • Journal Title: Oncogene Volume: - Pages: 5142-5157
  • DOI: 10.1038/s41388-019-0785-7
  • Peer Reviewed / Open Access
• [Journal Article] Definition of phosphoinositide distribution in the nanoscale (2019)
  • Author(s): Tsuji Takuma、Takatori Sho、Fujimoto Toyoshi
  • Journal Title: Curr Op Cell Biol Volume: 57 Pages: 33-39
  • DOI: 10.1016/j.ceb.2018.10.008
  • Peer Reviewed
• [Journal Article] Duo in a mystical realm - nuclear lipid droplets and the inner nuclear membrane. (2019)
  • Author(s): Soltysik K, Ohsaki Y, Fujimoto T.
  • Journal Title: Contact Volume: 2 Pages: 1-11
  • DOI: 10.1177/2515256419896965
  • Peer Reviewed / Open Access
• [Journal Article] 電子顕微鏡を用いた観察 (2019)
  • Author(s): 辻琢磨、藤本豊士
  • Journal Title: 実験医学（別冊）「脂質解析ハンドブック」 Volume: - Pages: 260-267
• [Journal Article] 核内脂肪滴の形成機序と機能の解明 (2019)
  • Author(s): 大崎雄樹、藤本豊士
  • Journal Title: The Lipid Volume: 30 Pages: 346-351
• [Journal Article] Regulation of plasma glycero-lysophospholipid levels by lipoprotein metabolism. (2019)
  • Author(s): Kurano M, Kano K, Hara M, Tsukamoto K, Aoki J, Yatomi Y.
  • Journal Title: Biochemical Journal Volume: 476 Pages: 3565-3581
  • DOI: 10.1042/bcj20190498
  • Peer Reviewed
• [Journal Article] Serum phosphatidylserine-specific phospholipase A1 as a novel biomarker for monitoring systemic lupus erythematosus disease activity. (2019)
  • Author(s): Sawada T, Kurano M, Shirai H, Iwasaki Y, Tahara K, Hayashi H, Igarashi K, Fujio K, Aoki J, Yatomi Y.
  • Journal Title: International Journal of Rheumatic Diseases Volume: 22 Pages: 2059-2066
  • DOI: 10.1111/1756-185x.13689
  • Peer Reviewed
• [Journal Article] Redox state of albumin affects its lipid mediator binding characteristics. (2019)
  • Author(s): Kurano M, Yasukawa K, Ikeda H, Aoki J, Yatomi Y.
  • Journal Title: Free Radical Research Volume: 53 Pages: 892-900
  • DOI: 10.1080/10715762.2019.1641603
  • Peer Reviewed
• [Journal Article] Evaluation of Lysophospholipid Measurement in Cerebrospinal Fluid Samples using Liquid Chromatography-Tandem Mass Spectrometry. (2019)
  • Author(s): Morita Y, Kurano M, Sakai E, Nishikawa M, Sawabe M, Aoki J, Yatomi Y.
  • Journal Title: Lipids Volume: 54 Pages: 487-500
  • DOI: 10.1002/lipd.12175
  • Peer Reviewed / Open Access
• [Journal Article] Serum GM3(d18:1-16:0) and GM3(d18:1-24:1) levels may be associated with lymphoma: An exploratory study with haematological diseases. (2019)
  • Author(s): Nishikawa M, Kurano M, Nitta T, Kanoh H, Inokuchi JI, Yatomi Y.
  • Journal Title: Scientific Reports Volume: 19 Pages: 6308-6308
  • DOI: 10.1038/s41598-019-42817-3
  • Peer Reviewed / Open Access
• [Journal Article] リポクオリティと臨床検査 (2019)
  • Author(s): 蔵野 信，矢冨 裕
  • Journal Title: The Lipid（メディカルレビュー社） Volume: 30 Pages: 417-423
• [Journal Article] 臨床検査におけるリポクオリティ (2019)
  • Author(s): 蔵野 信，矢冨 裕
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 269 Pages: 1251-1256
• [Journal Article] Creating a Reliable Mass Spectral-Retention Time Library for All Ion Fragmentation-Based Metabolomics (2019)
  • Author(s): Tada Ipputa、Tsugawa Hiroshi、Meister Isabel、Zhang Pei、Shu Rie、Katsumi Riho、Wheelock Craig E.、Arita Masanori、Chaleckis Romanas
  • Journal Title: Metabolites Volume: 9 Pages: 251-251
  • DOI: 10.3390/metabo9110251
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A cheminformatics approach to characterize metabolomes in stable-isotope-labeled organisms (2019)
  • Author(s): Tsugawa Hiroshi、Nakabayashi Ryo、Mori Tetsuya、Yamada Yutaka、Takahashi Mikiko、Rai Amit、Sugiyama Ryosuke、Yamamoto Hiroyuki、Nakaya Taiki、Yamazaki Mami、Kooke Rik、Bac-Molenaar Johanna A.、Oztolan-Erol Nihal、Keurentjes Joost J. B.、Arita Masanori、Saito Kazuki
  • Journal Title: Nat Methods Volume: 16 Pages: 295-298
  • DOI: 10.1038/s41592-019-0358-2
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dietary Intake of Green Nut Oil or DHA Ameliorates DHA Distribution in the Brain of a Mouse Model of Dementia Accompanied by Memory Recovery. (2019)
  • Author(s): Takeyama E, Islam A, Watanabe N, Tsubaki H, Fukushima M, Mamun MA, Sato S, Sato T, Eto F, Yao I, Ito TK, Horikawa M, Setou M.
  • Journal Title: Nutrients Volume: 11
  • DOI: 10.3390/nu11102371
  • Peer Reviewed / Open Access
• [Journal Article] Unsupervised machine learning using an imaging mass spectrometry dataset automatically reassembles grey and white matter. (2019)
  • Author(s): Nampei M, Horikawa M, Ishizu K, Yamazaki F, Yamada H, Kahyo T, Setou M.
  • Journal Title: Scientific Reports Volume: 9 Pages: 13213-13213
  • DOI: 10.1038/s41598-019-49819-1
  • Peer Reviewed / Open Access
• [Journal Article] Change in Brain Plasmalogen Composition by Exposure to Prenatal Undernutrition Leads to Behavioral Impairment of Rats (2019)
  • Author(s): Hino K, Udagawa J, et al.
  • Journal Title: J Neurosci Volume: 39 Pages: 7689-7702
  • DOI: 10.1523/jneurosci.2721-18.2019
  • NAID: 120006712956
  • Peer Reviewed / Open Access
• [Journal Article] Analysis of potential anti-aging beverage Pru, a traditional Cuban refreshment, by desorption electrospray innization-mass spectrometry and FTICR tandem mass spectrometry. (2019)
  • Author(s): Mamun MA, Valdes Gonzalez-T, Islam A, Sato T,Sato S, Ito KT, Horikawa M, Yamazaki Fm Alarcon RC, Ido T, Setou M.
  • Journal Title: Journal of Food and Drug Analysis Volume: 27 Pages: 833-840
  • DOI: 10.1016/j.jfda.2019.05.004
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] リポクオリティの可視化 (2019)
  • Author(s): 菊島健児、瀬藤光利
  • Journal Title: The Lipid Volume: 30 Pages: 67-74
• [Journal Article] イメージングMS (2019)
  • Author(s): 佐藤智仁、佐藤駿平、堀川誠、瀬藤光利
  • Journal Title: 実験医学別冊 Volume: - Pages: 268-276
• [Journal Article] 質量顕微鏡法 (2019)
  • Author(s): 荒牧修平、佐藤智仁、堀川誠、華表友暁、瀬藤光利
  • Journal Title: 炎症と免疫 Volume: 27 Pages: 79-82
  • NAID: 130001888663
• [Journal Article] 量子科学技術の生体応用 (2019)
  • Author(s): 荒牧修平、瀬藤光利
  • Journal Title: 脳神経外科 Volume: 17 Pages: 719-731
• [Journal Article] 組織リポクオリティのマスイメージング (2019)
  • Author(s): 櫻井孝信、瀬藤光利
  • Journal Title: 週刊 医学のあゆみ Volume: 269 Pages: 1245-1249
• [Journal Article] 細胞と組織の質量分析イメージング (2019)
  • Author(s): 大山壮歩、堀川誠、櫻井孝信、瀬藤光利
  • Journal Title: 化学工業 Volume: 70
• [Journal Article] Functional analysis of a double-point mutation in the KCNJ2 gene identified in a family with Andersen-Tawil syndrome. (2019)
  • Author(s): Fukumura S, Yamauchi K, Kawanabe A, Yamamoto A, Nakaza M, Kubota T, Kato S, Sasaki R, Okamura Y, Takahashi M.
  • Journal Title: Journal of the Neurological Sciences. Volume: 407 Pages: 0-0
  • Peer Reviewed
• [Journal Article] Distinct functional properties of two electrogenic isoforms of the SLC 34 Na‐Pi cotransporter (2019)
  • Author(s): Mizutani Natsuki、Okochi Yoshifumi、Okamura Yasushi
  • Journal Title: Physiol. Reports Volume: 7
  • DOI: 10.14814/phy2.14156
  • Peer Reviewed / Open Access
• [Journal Article] Real-time functional analysis of Hv1 channel in neutrophils: a new approach from zebrafish model (2019)
  • Author(s): Ratanayotha Adisorn、Kawai Takafumi、Okamura Yasushi
  • Journal Title: American Journal of Physiology Volume: 316 Pages: 819-831
  • DOI: 10.1152/ajpregu.00326.2018
  • Peer Reviewed
• [Journal Article] Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals (2019)
  • Author(s): Okamura Y, Okochi Y.
  • Journal Title: Proc Jpn Acad Ser B Phys Biol Sci. Volume: 95 Pages: 111-135
  • Peer Reviewed
• [Journal Article] Dynamic structural rearrangements and functional regulation of voltage-sensing phosphatase (2019)
  • Author(s): Sakata S .Okamura Y.
  • Journal Title: J. Physiol. Volume: 597 Pages: 29-40
  • Peer Reviewed
• [Journal Article] ホスフォイノシチドによるチャネル・トランスポーターの制御 (2019)
  • Author(s): 岡村康司、水谷夏希、大河内善史
  • Journal Title: 医学のあゆみ Volume: 269 Pages: 1108-1113
• [Journal Article] Cullin‐3/KCTD10 E3 complex is essential for Rac1 activation through RhoB degradation in human epidermal growth factor receptor 2‐positive breast cancer cells (2019)
  • Author(s): Murakami Akari、Maekawa Masashi、Kawai Katsuhisa、Nakayama Jun、Araki Nobukazu、Semba Kentaro、Taguchi Tomohiko、Kamei Yoshiaki、Takada Yasutsugu、Higashiyama Shigeki
  • Journal Title: Cancer Sci. Volume: 110 Pages: 650-661
  • DOI: 10.1111/cas.13899
  • Peer Reviewed / Open Access
• [Journal Article] FAM48A mediates compensatory autophagy induced by proteasome impairment. (2019)
  • Author(s): Arata Y, Watanabe A, Motosugi R, Iemura SI, Natsume T, Mukai K, Taguchi T, Hirayama S, Hamazaki J, Murata S.
  • Journal Title: Genes to Cells Volume: 24 Pages: 559-568
  • DOI: 10.1111/gtc.12708
  • Peer Reviewed / Open Access
• [Journal Article] Innate immunity signalling and membrane trafficking (2019)
  • Author(s): Taguchi Tomohiko、Mukai Kojiro
  • Journal Title: Curr. Opin. Cell Biol. Volume: 59 Pages: 1-7
  • DOI: 10.1016/j.ceb.2019.02.002
  • Peer Reviewed / Open Access
• [Journal Article] SNX9 determines the surface levels of integrin β1 in vascular endothelial cells: Implication in poor prognosis of human colorectal cancers overexpressing SNX9. (2019)
  • Author(s): Tanigawa K, Maekawa M, Kiyoi T, Nakayama J, Kitazawa R, Kitazawa S, Semba K, Taguchi T, Akita S, Yoshida M, Ishimaru K, Watanabe Y, Higashiyama S.
  • Journal Title: Journal of Cellular Physiology Volume: in press Pages: 17280-17294
  • DOI: 10.1002/jcp.28346
  • Peer Reviewed / Open Access
• [Journal Article] STING palmitoylation as a therapeutic target (2019)
  • Author(s): Hansen Anne Louise、Mukai Kojiro、Schopfer Francisco J.、Taguchi Tomohiko、Holm Christian K.
  • Journal Title: Cell Mol Immunol Volume: 16 Pages: 236-241
  • DOI: 10.1038/s41423-019-0205-5
  • Peer Reviewed / Open Access
• [Journal Article] Type I interferon limits mast-cell-mediated anaphylaxis by controlling secretory-granule homeostasis. (2019)
  • Author(s): Kobayashi T, Shimabukuro-Demoto S, Tsutsui H, Toyama-Sorimachi N
  • Journal Title: PLoS Biol. Volume: 17
  • DOI: 10.1371/journal.pbio.3000530
  • Peer Reviewed / Open Access
• [Journal Article] オルガネラを基軸とした炎症制御機構の理解と疾患治療戦略 (2019)
  • Author(s): 反町典子、Nguyen Tien Dat、小林俊彦
  • Journal Title: 臨床免疫・アレルギー科 Volume: 72 Pages: 313-321
• [Journal Article] リソソーム局在型アミノ酸トランスポーターを標的とした免疫難病治療への挑戦 (2019)
  • Author(s): 反町典子、小林俊彦
  • Journal Title: 医学のあゆみ Volume: 271 Pages: 17-25
• [Journal Article] Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis (2019)
  • Author(s): Soltysik K., Ohsaki Y., Tatematsu T., Cheng J., Fujimoto T.
  • Journal Title: Nature Communications Volume: 10 Pages: 473-473
  • DOI: 10.1038/s41467-019-08411-x
  • Peer Reviewed / Open Access
• [Journal Article] Autotaxin and soluble IL-2 receptor concentrations in cerebrospinal fluids are useful for the diagnosis of central nervous system invasion caused by haematological malignancies (2019)
  • Author(s): Shimura Takuya、Kurano Makoto、Morita Yoshifumi、Yoshikawa Naoyuki、Nishikawa Masako、Igarashi Koji、Shimamoto Satoshi、Aoki Junken、Yatomi Yutaka
  • Journal Title: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine Volume: 56 Pages: 240-246
  • DOI: 10.1177/0004563218818197
  • Peer Reviewed
• [Journal Article] Apolipoprotein M suppresses the phenotypes of IgA nephropathy in hyper-IgA mice (2019)
  • Author(s): Kurano Makoto、Tsuneyama Koichi、Morimoto Yuki、Nishikawa Masako、Yatomi Yutaka
  • Journal Title: The FASEB Journal Volume: 33 Pages: 5181-5195
  • DOI: 10.1096/fj.201801748r
  • Peer Reviewed
• [Journal Article] Serum autotaxin levels are associated with Graves’ disease (2019)
  • Author(s): Nojiri Takahiro、Kurano Makoto、Araki Osamu、Nakawatari Kazuki、Nishikawa Masako、Shimamoto Satoshi、Igarashi Koji、Kano Kuniyuki、Aoki Junken、Kihara Shinji、Murakami Masami、Yatomi Yutaka
  • Journal Title: Endocr J Volume: - Issue: 5 Pages: 409-422
  • DOI: 10.1507/endocrj.ej18-0451 10.1507/endocrj.EJ18-0451
  • NAID: 130007655267
  • ISSN: 0918-8959, 1348-4540
  • Peer Reviewed / Open Access
• [Journal Article] Molecular mechanisms of coupling to voltage sensors in voltage-evoked cellular signals (2019)
  • Author(s): OKAMURA Yasushi、OKOCHI Yoshifumi
  • Journal Title: Proc. Jpn. Acad., Ser. B Volume: 95 Issue: 3 Pages: 111-135
  • DOI: 10.2183/pjab.95.010
  • NAID: 130007610041
  • ISSN: 0386-2208, 1349-2896
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Dynamic structural rearrangements and functional regulation of voltage‐sensing phosphatase (2019)
  • Author(s): Sakata S and Okamura Y
  • Journal Title: The Journal of Physiology Volume: 597 Pages: 29-40
  • DOI: 10.1113/jp274113
  • Peer Reviewed / Open Access
• [Journal Article] NaV チャネル全史-細菌からヒトまで- (2019)
  • Author(s): 西野 敦雄，岡村 康司
  • Journal Title: 生化学 Volume: 91 Pages: 1-14
• [Journal Article] アレルギー性好酸球における脂質代謝異常のメタボローム解析 (2019)
  • Author(s): 宮田純、有田誠
  • Journal Title: 臨床免疫・アレルギー科（科学評論社） Volume: 71 Pages: 34-40
• [Journal Article] Discovery of lipid biomarkers correlated with disease progression in clear cell renal cell carcinoma using desorption electrospray ionization imaging mass spectrometry (2019)
  • Author(s): Tamura Keita、Horikawa Makoto、Sato Shumpei、Miyake Hideaki、Setou Mitsutoshi
  • Journal Title: Oncotarget Volume: 10 Pages: 1688-1703
  • DOI: 10.18632/oncotarget.26706
  • Peer Reviewed / Open Access
• [Journal Article] MALDI imaging mass spectrometry revealed atropine distribution in the ocular tissues and its transit from anterior to posterior regions in the whole-eye of rabbit after topical administration (2019)
  • Author(s): Mori Naoto、Mochizuki Takaharu、Yamazaki Fumiyoshi、Takei Shiro、Mano Hidetoshi、Matsugi Takeshi、Setou Mitsutoshi
  • Journal Title: PLOS ONE Volume: 14 Pages: 0211376-0211376
  • DOI: 10.1371/journal.pone.0211376
  • Peer Reviewed / Open Access
• [Journal Article] Lysophosphatidic acid precursor levels decrease and an arachidonic acid-containing phosphatidylcholine level increases in the dorsal root ganglion of mice after peripheral nerve injury (2019)
  • Author(s): Mihara Yuki、Horikawa Makoto、Sato Shumpei、Eto Fumihiro、Hanada Mitsuru、Banno Tomohiro、Arima Hideyuki、Ushirozako Hiroki、Yamada Tomohiro、Xu Dongmin、Okamoto Ayako、Yamazaki Fumiyoshi、Takei Shiro、Omura Takao、Yao Ikuko、Matsuyama Yukihiro、Setou Mitsutoshi
  • Journal Title: Neuroscience letters Volume: 698 Pages: 69-75
  • DOI: 10.1016/j.neulet.2018.12.035
  • Peer Reviewed / Open Access
• [Journal Article] Dietary omega-3 fatty acids alter the lipid mediator profile and alleviate allergic conjunctivitis without modulating Th2 immune responses. (2019)
  • Author(s): Hirakata T., Lee H. C., Ohba M., Saeki K., Okuno T., Murakami A., Matsuda A., Yokomizo T.
  • Journal Title: The FASEB Journal Volume: 33 Pages: 3392-3403
  • DOI: 10.1096/fj.201801805r
  • Peer Reviewed / Open Access
• [Journal Article] Transcriptome profiling of refractory atopic keratoconjunctivitis by RNA sequencing (2019)
  • Author(s): Matsuda Akira、Asada Yosuke、Suita Naomasa、Iwamoto Satoshi、Hirakata Toshiaki、Yokoi Norihiko、Ohkawa Yasuyuki、Okada Yukinori、Yokomizo Takehiko、Ebihara Nobuyuki
  • Journal Title: J Allergy Clin Immunol Volume: 143 Pages: 1610-1614
  • DOI: 10.1016/j.jaci.2018.11.007
  • Peer Reviewed / Open Access
• [Journal Article] Autophagy regulates lipid metabolism through selective turnover of NCoRl (2019)
  • Author(s): Saito Tetsuya、Kuma Akiko、Sugiura Yuki、Ichimura Yoshinobu、Obata Miki、Kitamura Hiroshi、Okuda Shujiro、Lee Hyeon-Cheol、Ikeda Kazutaka、Kanegae Yumi、Saito Izumu、Auwerx Johan、Motohashi Hozumi、Suematsu Makoto、Soga Tomoyoshi、Yokomizo Takehiko、Waguri Satoshi、Mizushima Noboru、Komatsu Masaaki
  • Journal Title: Nature Communication Volume: 10 Issue: 1 Pages: 1567-1567
  • DOI: 10.1038/s41467-019-08829-3
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Lipids and lipid domains of the yeast vacuole (2018)
  • Author(s): Tsuji Takuma、Fujimoto Toyoshi
  • Journal Title: Biochemical Society transactions Volume: 46 Pages: 1047-1054
  • DOI: 10.1042/bst20180120
  • NAID: 120006554476
  • Peer Reviewed
• [Journal Article] Nuclear phosphatidylinositol 4,5-bisphosphate islets contribute to efficient RNA polymerase II-dependent transcription (2018)
  • Author(s): Sobol Margarita、Krausova Alzbeta、Yildirim Sukriye、Kalasova Ilona、Faberova Veronika、Vrkoslav Vladimir、Philimonenko Vlada、Marasek Pavel、Pastorek Lukas、Capek Martin、Lubovska Zuzana、Ulicna Livia、Tsuji Takuma、Lisa Miroslav、Cvacka Josef、Fujimoto Toyoshi、Hozak Pavel
  • Journal Title: Journal of cell science Volume: 131
  • DOI: 10.1242/jcs.211094
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Syntaxin 17 promotes lipid droplet formation by regulating the distribution of acyl-CoA synthetase 3. (2018)
  • Author(s): Kimura H, Arasaki K, Ohsaki Y, Fujimoto T, Ohtomo T, Yamada J, Tagaya M.
  • Journal Title: J. Lipid Res. Volume: in press Pages: 805-819
  • DOI: 10.1194/jlr.m081679
  • Peer Reviewed
• [Journal Article] UBXN3B positively regulates STING-mediated antiviral immune responses (2018)
  • Author(s): Yang Long、Wang Leilei、Ketkar Harshada、Ma Jinzhu、Yang Guang、Cui Shuang、Geng Tingting、Mordue Dana G.、Fujimoto Toyoshi、Cheng Gong、You Fuping、Lin Rongtuan、Fikrig Erol、Wang Penghua
  • Journal Title: Nature Communications Volume: 9 Pages: 2329-2329
  • DOI: 10.1038/s41467-018-04759-8
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Syntaxin 17 regulates the localization and function of PGAM5 in mitochondrial division and mitophagy (2018)
  • Author(s): Sugo Masashi、Kimura Hana、Arasaki Kohei、Amemiya Toshiki、Hirota Naohiko、Dohmae Naoshi、Imai Yuzuru、Inoshita Tsuyoshi、Shiba‐Fukushima Kahori、Hattori Nobutaka、Cheng Jinglei、Fujimoto Toyoshi、Wakana Yuichi、Inoue Hiroki、Tagaya Mitsuo
  • Journal Title: EMBO J. Volume: 37
  • DOI: 10.15252/embj.201798899
  • Peer Reviewed / Open Access
• [Journal Article] Immunoelectron Microscopy of Gangliosides (2018)
  • Author(s): Tsuji Takuma、Fujita Akikazu、Fujimoto Toyoshi
  • Journal Title: Immunoelectron Microscopy of Gangliosides Volume: 1804 Pages: 231-239
  • DOI: 10.1007/978-1-4939-8552-4_11
  • Peer Reviewed
• [Journal Article] 膜リン脂質クオリティの可視化 (2018)
  • Author(s): 辻琢磨、藤本豊士
  • Journal Title: 実験医学 Volume: 36 Pages: 89-96
• [Journal Article] プロスタグランジンE2による炎症病態制御機構 (2018)
  • Author(s): 稲住知明, 杉本幸彦.
  • Journal Title: 細胞. Volume: 50 Pages: 118-121
• [Journal Article] リポクオリティの違いに基づくプロスタノイドのがん疾患制御 (2018)
  • Author(s): 土屋創健, 杉本幸彦.
  • Journal Title: 実験医学 Volume: 36 Pages: 1675-1680
• [Journal Article] プロスタグランジンE2による炎症，免疫調節機構. (2018)
  • Author(s): 稲住知明, 杉本幸彦.
  • Journal Title: 臨床免疫・アレルギー科. 炎症と免疫. Volume: 70 Pages: 216-220
• [Journal Article] プロスタノイド受容体を介した免疫・炎症応答亢進機構. (2018)
  • Author(s): 土屋創健, 杉本幸彦
  • Journal Title: 炎症と免疫. Volume: 26 Pages: 375-379
• [Journal Article] Epithelial TRAF6 drives IL-17?mediated psoriatic inflammation (2018)
  • Author(s): Matsumoto Reiko、Dainichi Teruki、Tsuchiya Soken、Nomura Takashi、Kitoh Akihiko、Hayden Matthew S.、Ishii Ken J.、Tanaka Mayuri、Honda Tetsuya、Egawa Gyohei、Otsuka Atsushi、Nakajima Saeko、Sakurai Kenji、Nakano Yuri、Kobayashi Takashi、Sugimoto Yukihiko、Kabashima Kenji
  • Journal Title: JCI Insight. Volume: 3 Pages: 1-14
  • DOI: 10.1172/jci.insight.121175
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Preventive effect of <i>Dioscorea japonica</i> on squamous cell carcinoma of mouse skin involving down-regulation of prostaglandin E₂ synthetic pathway (2018)
  • Author(s): Tsukayama I, Toda K, Takeda Y, Mega T, Tanaka M, Kawakami Y, Takahashi Y, Kimoto M, Yamamoto K, Miki Y, Murakami M, Suzuki-Yamamoto T.
  • Journal Title: J. Clin. Biochem. Nutr. Volume: 62 Issue: 2 Pages: 139-147
  • DOI: 10.3164/jcbn.17-54
  • NAID: 130006407477
  • ISSN: 0912-0009, 1880-5086
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] イノシトールリン脂質におけるリン酸化クオリティ制御の病態生理学的意義 (2018)
  • Author(s): 高須賀俊輔、佐々木雄彦
  • Journal Title: 実験医学増刊（羊土社） Volume: 36 Pages: 1591-1607
• [Journal Article] TMEM55a localizes to macrophage phagosomes to downregulate phagocytosis (2018)
  • Author(s): Morioka Shin、Nigorikawa Kiyomi、Okada Eri、Tanaka Yoshimasa、Kasuu Yoshihiro、Yamada Miho、Kofuji Satoshi、Takasuga Shunsuke、Nakanishi Hiroki、Sasaki Takehiko、Hazeki Kaoru
  • Journal Title: Journal of Cell Science Volume: 131 Pages: 213272-213272
  • DOI: 10.1242/jcs.213272
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Metabolic determinants of sensitivity to phosphatidylinositol 3-kinase pathway inhibitor in small-cell lung carcinoma (2018)
  • Author(s): Makinoshima H et al.
  • Journal Title: Cancer Res Volume: - Pages: 2179-2190
  • DOI: 10.1158/0008-5472.can-17-2109
  • Peer Reviewed / Open Access
• [Journal Article] PIKfyve regulates melanosome biogenesis (2018)
  • Author(s): Liggins Marc C.、Flesher Jessica L.、Jahid Sohail、Vasudeva Priya、Eby Victoria、Takasuga Shunsuke、Sasaki Junko、Sasaki Takehiko、Boissy Raymond E.、Ganesan Anand K.
  • Journal Title: PLOS Genetics Volume: 14
  • DOI: 10.1371/journal.pgen.1007290
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 脂肪酸クオリティに着目した新しい臨床検査への可能性． (2018)
  • Author(s): 蔵野 信，矢冨 裕．
  • Journal Title: 医学のあゆみ Volume: 264 Pages: 979-983
• [Journal Article] リゾリン脂質と病態 (2018)
  • Author(s): 蔵野 信，矢冨 裕．
  • Journal Title: 細胞 Volume: 50 Pages: 132-135
• [Journal Article] リポクオリティに注目した臨床検査の可能性 (2018)
  • Author(s): 蔵野 信，矢冨 裕．
  • Journal Title: 実験医学 Volume: 36 Pages: 1767-1772
• [Journal Article] ヒト疾患におけるリゾリン脂質メディエーター． (2018)
  • Author(s): 蔵野 信，矢冨 裕．
  • Journal Title: 生化学 Volume: 90 Pages: 643-650
• [Journal Article] Evidence Suggests Sphingosine 1-Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer. (2018)
  • Author(s): Uranbileg B, Nishikawa T, Ikeda H, Kurano M, Sato M, Saigusa D, Aoki J, Watanabe T, Yatomi Y.
  • Journal Title: Clinical Colorectal Cancer Volume: Nov 21. pii: Pages: 30369-9
  • DOI: 10.1016/j.clcc.2017.11.004
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Association between serum autotaxin or phosphatidylserine-specific phospholipase A1 levels and melanoma (2018)
  • Author(s): Kurano Makoto、Miyagaki Tomomitsu、Miyagawa Takuya、Igarashi Koji、Shimamoto Satoshi、Ikeda Hitoshi、Aoki Junken、Sato Shinichi、Yatomi Yutaka
  • Journal Title: The Journal of Dermatology Volume: - Pages: 571-579
  • DOI: 10.1111/1346-8138.14278
  • Peer Reviewed
• [Journal Article] Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay (2018)
  • Author(s): Ohkawa Ryunosuke、Kurano Makoto、Sakai Noboru、Kishimoto Tatsuya、Nojiri Takahiro、Igarashi Koji、Hosogaya Shigemi、Ozaki Yukio、Dohi Tomotaka、Miyauchi Katsumi、Daida Hiroyuki、Aoki Junken、Okubo Shigeo、Ikeda Hitoshi、Tozuka Minoru、Yatomi Yutaka
  • Journal Title: Sci Rep. Volume: 8 Pages: 1-12
  • DOI: 10.1038/s41598-018-23009-x
  • Peer Reviewed / Open Access
• [Journal Article] Apolipoprotein M Protects Lipopolysaccharide-Treated Mice from Death and Organ Injury. (2018)
  • Author(s): Kurano M, Tsuneyama K, Morimoto Y, Shimizu T, Jona M, Kassai H, Nakao K, Aiba A, Yatomi Y
  • Journal Title: Thrombosis and Haemostasis Volume: 印刷中 Pages: 1021-1035
  • DOI: 10.1055/s-0038-1641750
  • Peer Reviewed
• [Journal Article] Regulation of the metabolism of apolipoprotein M and sphingosine 1-phosphate by hepatic PPARγ activity (2018)
  • Author(s): Kurano Makoto、Ikeda Hitoshi、Iso-O Naoyuki、Hara Masumi、Tsukamoto Kazuhisa、Yatomi Yutaka
  • Journal Title: Biochemical Journal Volume: 475 Pages: 2009-2024
  • DOI: 10.1042/bcj20180052
  • Peer Reviewed
• [Journal Article] Increased aqueous autotaxin and lysophosphatidic acid levels are potential prognostic factors after trabeculectomy in different types of glaucoma (2018)
  • Author(s): Igarashi Nozomi、Honjo Megumi、Kurano Makoto、Yatomi Yutaka、Igarashi Koji、Kano Kuniyuki、Aoki Junken、Aihara Makoto
  • Journal Title: Scientific Reports Volume: 8 Pages: 11304-11304
  • DOI: 10.1038/s41598-018-29649-3
  • Peer Reviewed / Open Access
• [Journal Article] Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate (2018)
  • Author(s): Mishima Yuko、Kurano Makoto、Kobayashi Tamaki、Nishikawa Masako、Ohkawa Ryunosuke、Tozuka Minoru、Yatomi Yutaka
  • Journal Title: Bioscience Reports Volume: 38
  • DOI: 10.1042/bsr20181288
  • Peer Reviewed / Open Access
• [Journal Article] Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study (2018)
  • Author(s): Kuwajima Ken、Sumitani Masahiko、Kurano Makoto、Kano Kuniyuki、Nishikawa Masako、Uranbileg Baasanjav、Tsuchida Rikuhei、Ogata Toru、Aoki Junken、Yatomi Yutaka、Yamada Yoshitsugu
  • Journal Title: PLOS ONE Volume: 13 Pages: 0207310-0207310
  • DOI: 10.1371/journal.pone.0207310
  • Peer Reviewed / Open Access
• [Journal Article] Lysophospholipids in laboratory medicine (2018)
  • Author(s): YATOMI Yutaka、KURANO Makoto、IKEDA Hitoshi、IGARASHI Koji、KANO Kuniyuki、AOKI Junken
  • Journal Title: Proc. Jpn. Acad., Ser. B Volume: 94 Issue: 10 Pages: 373-389
  • DOI: 10.2183/pjab.94.025
  • NAID: 130007529097
  • ISSN: 0386-2208, 1349-2896
  • Peer Reviewed
• [Journal Article] リポクオリティ認識プローブの開発と応用 (2018)
  • Author(s): 田口友彦，小林俊彦，反町典子，仁木隆裕
  • Journal Title: 実験医学 Volume: 36 Pages: 217-221
• [Journal Article] エンドリソソーム環境に依存した自然免疫応答偏向 (2018)
  • Author(s): 反町典子、小林俊彦
  • Journal Title: 医学のあゆみ Volume: 265 Pages: 1094-1100
• [Journal Article] 炎症・感染応答を担うオルガネラ (2018)
  • Author(s): 小林俊彦、向井康治朗、田口友彦、反町典子
  • Journal Title: 臨床免疫・アレルギー科 Volume: 69 Pages: 99-106
• [Journal Article] Exosome-associated Shiga toxin 2 is released from cells and causes severe toxicity in mice (2018)
  • Author(s): Watanabe-Takahashi, M., Yamasaki, S., Murata, M., Kano, F., Motoyama, J., Yamate, J., Omi, J., Sato, W., Ukai, H., Shimasaki, K., Ikegawa, M., Tamura-Nakano, M., Yanoshita, R., Nishino, Y., Miyazawa, A., Natori, Y., Toyama-Sorimachi, N., Nishikawa, N.
  • Journal Title: Sci Rep. Volume: 8 Pages: 10776-10776
  • DOI: 10.1038/s41598-018-29128-9
  • Peer Reviewed / Open Access
• [Journal Article] Evolutionary History of Voltage-Gated Sodium Channels. (2018)
  • Author(s): Nishino Atsuo, Okamura Yasushi
  • Journal Title: Handbook of Experimental Pharmacology, Springer Volume: Epub ahead of print Pages: 1-30
  • DOI: 10.1007/164_2017_70
  • Peer Reviewed
• [Journal Article] Induction of divalent cation permeability by heterologous expression of a voltage sensor domain (2018)
  • Author(s): Arima Hiroki、Tsutsui Hidekazu、Sakamoto Ayako、Yoshida Manabu、Okamura Yasushi
  • Journal Title: Biochimica et Biophysica Acta (BBA) - Biomembranes Volume: 1860 Pages: 981-990
  • DOI: 10.1016/j.bbamem.2018.01.004
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Conservation of the Ca2+-permeability through the voltage sensor domain of mammalian CatSper subunit (2018)
  • Author(s): Arima Hiroki、Tsutsui Hidekazu、Okamura Yasushi
  • Journal Title: Channels Volume: 12 Pages: 240-248
  • DOI: 10.1080/19336950.2018.1476791
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Tracking the sarcoplasmic reticulum membrane voltage in muscle with a FRET biosensor (2018)
  • Author(s): Sanchez Colline、Berthier Christine、Allard Bruno、Perrot Jimmy、Bouvard Cl?ment、Tsutsui Hidekazu、Okamura Yasushi、Jacquemond Vincent
  • Journal Title: The Journal of General Physiology Volume: 150 Pages: 1163-1177
  • DOI: 10.1085/jgp.201812035
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] Zn2+-Binding to the Voltage-Gated Proton Channel Hv1/VSOP (2018)
  • Author(s): Iwaki Masayo、Takeshita Kohei、Kondo Hiroko X.、Kinoshita Kengo、Okamura Yasushi、Takano Yu、Nakagawa Atsushi、Kandori Hideki
  • Journal Title: The Journal of Physical Chemistry B Volume: 122 Pages: 9076-9080
  • DOI: 10.1021/acs.jpcb.8b04890
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] The hydrophobic nature of a novel membrane interface regulates the enzyme activity of a voltage-sensing phosphatase (2018)
  • Author(s): Kawanabe A, Hashimoto M, Mishizawa M, Nishizawa N, Narita H, Yonezawa T, Jinno Y, Sakata S, Nakawaga A and Okamura Y
  • Journal Title: eLife Volume: 7 Pages: 2097-2131
  • DOI: 10.7554/elife.41653
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Voltage-Sensing Phosphatases: Biophysics, Physiology, and Molecular Engineering (2018)
  • Author(s): Okamura Yasushi、Kawanabe Akira、Kawai Takafumi
  • Journal Title: Physiological Reviews Volume: 98 Pages: 2097-2131
  • DOI: 10.1152/physrev.00056.2017
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 脂質－イオンチャネル相互連関 (2018)
  • Author(s): 岡村康司、大澤匡範
  • Journal Title: 「脂質クオリティ」実験医学増刊 Volume: 36 Pages: 97-104
• [Journal Article] Proteogenomic Analyses of Cellular Lysates Using a Phenol-Guanidinium Thiocyanate Reagent (2018)
  • Author(s): Kawashima Yusuke、Miyata Jun、Watanabe Takashi、Shioya Juri、Arita Makoto、Ohara Osamu
  • Journal Title: Journal of Proteome Research Volume: 18 Pages: 301-308
  • DOI: 10.1021/acs.jproteome.8b00609
  • Peer Reviewed
• [Journal Article] Reelin deficiency leads to aberrant lipid composition in mouse brain. (2018)
  • Author(s): Mizukami T, Ikeda K, Shimanaka Y, Korogi K, Zhou C, Takase H, Tsuiji H, Kono N, Kohno T, Arai H, Arita M, Hattori M.
  • Journal Title: Biochem Biophys Res Commun. Volume: 505 Pages: 81-86
  • DOI: 10.1016/j.bbrc.2018.09.089
  • Peer Reviewed
• [Journal Article] An omega-3 polyunsaturated fatty acid derivative, 18-HEPE, protects against CXCR4-associated melanoma metastasis (2018)
  • Author(s): Li Jieping、Chen Chih-Yu、Arita Makoto、Kim Kuijin、Li Xiangyong、Zhang Hongman、Kang Jing X
  • Journal Title: Carcinogenesis Volume: 39 Pages: 1380-1388
  • DOI: 10.1093/carcin/bgy117
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] MS-based lipidomics of human blood plasma: a community-initiated position paper to develop accepted guidelines (2018)
  • Author(s): Burla Bo、Arita Makoto、Arita Masanori et al.
  • Journal Title: Journal of Lipid Research Volume: 59 Pages: 2001-2017
  • DOI: 10.1194/jlr.s087163
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Thromboxane A2 facilitates IL-17A production from Vγ4+ γδ T cells and promotes psoriatic dermatitis in mice. (2018)
  • Author(s): Ueharaguchi Y, Honda T, Kusuba N, Hanakawa S, Adachi A, Sawada Y, Otsuka A, Kitoh A, Dainich T, Egawa G, Nakachima C, Nakajima S, Murata T, Ono S, Arita M, Narumiya S, Miyachi Y, Kabashima K
  • Journal Title: J Allergy Clin Immunol. Volume: in press
  • DOI: 10.1016/j.jaci.2018.01.054
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 17,18-EpETE-GPR40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques (2018)
  • Author(s): Nagatake T, Shiogama Y, Inoue A, Kikuta J, Honda T, Tiwari P, Kishi T, Yanagisawa A, Isobe Y, Matsumoto N, Shimojou M, Morimoto S, Suzuki H, Hirata S, Steneberg P, Edlund H, Aoki J, Arita M, Kiyono H, Yasutomi Y, Ishii M, Kabashima K, Kunisawa J
  • Journal Title: J Allergy Clin Immunol. Volume: S0091-6749 Pages: 32949-32944
  • DOI: 10.1016/j.jaci.2017.09.053
  • NAID: 40021650879
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] A bacterial metabolite ameliorates periodontal pathogen-induced gingival epithelial barrier disruption via GPR40 signaling (2018)
  • Author(s): Yamada M, Takahashi N, Matsuda Y, Sato K, Yokoji M, Sulijaya B, Maekawa T, Ushiki T, Mikami Y, Hayatsu M, Mizutani Y, Kishino S, Ogawa J, Arita M, Tabeta K, Maeda T, Yamazaki K
  • Journal Title: Sci Rep Volume: 8 Pages: 1-12
  • DOI: 10.1038/s41598-018-27408-y
  • NAID: 120006546008
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive analysis of the mouse cytochrome P450 family responsible for omega-3 epoxidation of eicosapentaenoic acid (2018)
  • Author(s): Isobe Yosuke、Itagaki Mai、Ito Yuko、Naoe Satoko、Kojima Kotoe、Ikeguchi Mitsunori、Arita Makoto
  • Journal Title: Scientific Reports Volume: 8 Pages: 7954-7954
  • DOI: 10.1038/s41598-018-26325-4
  • Peer Reviewed / Open Access
• [Journal Article] Facile determination of sphingolipids under alkali condition using metal-free column by LC-MS/MS (2018)
  • Author(s): B. Gowda Siddabasave Gowda、Ikeda Kazutaka、Arita Makoto
  • Journal Title: Analytical and Bioanalytical Chemistry Volume: 410 Pages: 4793-4803
  • DOI: 10.1007/s00216-018-1116-5
  • Peer Reviewed
• [Journal Article] Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes (2018)
  • Author(s): Hata Masayuki、Ikeda Hanako O.、Iwai Sachiko、Iida Yuto、Gotoh Norimoto、Asaka Isao、Ikeda Kazutaka、Isobe Yosuke、Hori Aya、Nakagawa Saori、Yamato Susumu、Arita Makoto、Yoshimura Nagahisa、Tsujikawa Akitaka
  • Journal Title: Proc Natl Acad Sci U S A Volume: 115 Pages: 3936-3941
  • DOI: 10.1073/pnas.1717338115
  • NAID: 120006416205
  • Peer Reviewed / Open Access
• [Journal Article] Identification of Protein Targets of 12/15-Lipoxygenase-Derived Lipid Electrophiles in Mouse Peritoneal Macrophages Using Omega-Alkynyl Fatty Acid (2018)
  • Author(s): Isobe Yosuke、Kawashima Yusuke、Ishihara Tomoaki、Watanabe Kenji、Ohara Osamu、Arita Makoto
  • Journal Title: ACS Chem Biol. Volume: 13 Pages: 887-893
  • DOI: 10.1021/acschembio.7b01092
  • Peer Reviewed / Open Access
• [Journal Article] 脂肪酸代謝バランスによるマクロファージの機能制御 (2018)
  • Author(s): 青木秀憲、有田誠
  • Journal Title: 実験医学（羊土社） Volume: 36 Pages: 2353-2357
• [Journal Article] 「脂質クオリティ」生命機能と健康を支える脂質の多様性（企画・編集） (2018)
  • Author(s): 有田誠
  • Journal Title: 実験医学増刊（羊土社） Volume: 36
• [Journal Article] 概論/リポクオリティから解き明かす生命現象 (2018)
  • Author(s): 有田誠
  • Journal Title: 実験医学増刊（羊土社） Volume: 36 Pages: 1580-1584
• [Journal Article] リポクオリティを識別するリピドミクス解析技術 (2018)
  • Author(s): 池田和貴、青柳良平、有田誠
  • Journal Title: 実験医学増刊（羊土社） Volume: 36 Pages: 1797-1803
• [Journal Article] 脂質クオリティを捉える解析手法とデータベース (2018)
  • Author(s): 津川裕司、池田和貴、有田誠、有田正規
  • Journal Title: 実験医学増刊（羊土社） Volume: 36 Pages: 1804-1811
• [Journal Article] UBL3 modification influences protein sorting to small extracellular vesicles. (2018)
  • Author(s): Ageta H, Ageta-Ishihara N, Hitachi K, Karayel O, Onouchi T, Yamaguchi H, Kahyo T, Hatanaka K, Ikegami K, Yoshioka Y, Nakamura K, Kosaka N, Nakatani M, Uezumi A, Ide T, Tsutsumi Y, Sugimura H, Kinoshita M, Ochiya T, Mann M, Setou M, Tsuchida K.
  • Journal Title: Nature Communications Volume: 9 Pages: 1-14
  • DOI: 10.1038/s41467-018-06197-y
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Role of caveolin-1 in hepatocellular carcinoma arising from non-alcoholic fatty liver disease (2018)
  • Author(s): Takeda Makoto、Sakaguchi Takanori、Hiraide Takanori、Shibasaki Yasushi、Morita Yoshifumi、Kikuchi Hirotoshi、Ikegami Koji、Setou Mitsutoshi、Konno Hiroyuki、Takeuchi Hiroya
  • Journal Title: Cancer Science Volume: 109 Pages: 2401-2411
  • DOI: 10.1111/cas.13659
  • Peer Reviewed / Open Access
• [Journal Article] A power law distribution of metabolite abundance levels in mice regardless of the time and spatial scale of analysis (2018)
  • Author(s): Sato Shumpei、Horikawa Makoto、Kondo Takeshi、Sato Tomohito、Setou Mitsutoshi
  • Journal Title: Scientific Reports Volume: 8 Pages: 10315-10315
  • DOI: 10.1038/s41598-018-28667-5
  • Peer Reviewed / Open Access
• [Journal Article] リポクオリティの可視化と操作 (2018)
  • Author(s): 堀川誠、武井史郎、瀬藤光利
  • Journal Title: 実験医学増刊（羊土社） Volume: 36 Pages: 103-210
• [Journal Article] The Relationship between TP53 Gene Status and Carboxylesterase 2 Expression in Human Colorectal Cancer (2018)
  • Author(s): Ishimine M, Lee HC, Nakaoka H, Orita H, Kobayashi T, Mizuguchi K, Endo M, Inoue I, Sato K, Yokomizo T
  • Journal Title: Dis Markers Volume: － Pages: 1-7
  • DOI: 10.1155/2018/5280736
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Urinary prostaglandin D2 metabolite excretion during the first six months of life was significantly lower in breast-fed than formula-fed infants (2018)
  • Author(s): Shoji Hiromichi、Ikeda Naho、Kitamura Tomohiro、Suganuma Hiroki、Ohba Mai、Okuno Toshiaki、Yokomizo Takehiko、Shimizu Toshiaki
  • Journal Title: Acta Paediatr Volume: 107 Pages: 95-100
  • DOI: 10.1111/apa.14068
  • Peer Reviewed / Open Access
• [Journal Article] Endurance exercise training and high-fat diet differentially affect composition of diacylglycerol molecular species in rat skeletal muscle (2018)
  • Author(s): Kawanishi Noriaki、Takagi Kana、Lee Hyeon-Cheol、Nakano Daiki、Okuno Toshiaki、Yokomizo Takehiko、Machida Shuichi
  • Journal Title: Am J Physiol Regul Integr Comp Physiol Volume: 印刷中
  • DOI: 10.1152/ajpregu.00371.2017
  • Peer Reviewed / Open Access
• [Journal Article] Na+-mimicking ligands stabilize the inactive state of leukotriene B4 receptor BLT1 (2018)
  • Author(s): Hori Tetsuya、Okuno Toshiaki、Hirata Kunio、Yamashita Keitaro、Kawano Yoshiaki、Yamamoto Masaki、Hato Masakatsu、Nakamura Motonao、Shimizu Takao、Yokomizo Takehiko、Miyano Masashi、Yokoyama Shigeyuki
  • Journal Title: Nat Chem Biol Volume: 14 Pages: 262-269
  • DOI: 10.1038/nchembio.2547
  • Peer Reviewed / Open Access
• [Journal Article] Altered eicosanoid production and phospholipid remodeling during cell culture (2018)
  • Author(s): Okuno Toshiaki、Gij?n Miguel A.、Zarini Simona、Martin Sarah A.、Barkley Robert M.、Johnson Christopher A.、Ohba Mai、Yokomizo Takehiko、Murphy Robert C.
  • Journal Title: J Lipid Res Volume: 59 Pages: 542-549
  • DOI: 10.1194/jlr.m083030
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Leukotriene B4 receptor 2 regulates the proliferation migration and barrier integrity of bronchial epithelial cells (2018)
  • Author(s): M Liu J Shen H Yuan F Chen H Song H Qin Y Li J Xu Q Ye S Li K Saeki T Yokomizo
  • Journal Title: Journal of Cellular Physiology Volume: 印刷中 Pages: 6117-6124
  • DOI: 10.1002/jcp.26455
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Stepwise phosphorylation of leukotriene B4 receptor 1 defines cellular responses to leukotriene B4. (2018)
  • Author(s): Nakanishi,Y., Tan,M., Ichiki,T., Inoue,A. Yoshihara,J., Maekawa,N., Takenoshita.I., Yanagida,K., Yamahira,S., Yamaguchi,S., Aoki,J. Nagamune,T., Yokomizo,T., Shimizu,T., and Nakamura,M
  • Journal Title: Science Signaling Volume: 11 (544) Pages: 5390-5390
  • DOI: 10.1126/scisignal.aao5390
  • Peer Reviewed / Open Access
• [Journal Article] Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method. (2018)
  • Author(s): Ohba M., Saeki K., Koga T., Okuno T., Kobayashi Y., Yokomizo T.
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 504 Pages: 562-568
  • DOI: 10.1016/j.bbrc.2018.06.026
  • Peer Reviewed / Open Access
• [Journal Article] Leukotriene B4 promotes neovascularization and macrophage recruitment in murine wet-type AMD models. (2018)
  • Author(s): Sasaki F., Koga T., Ohba M., Saeki K., Okuno T., Ishikawa K., Nakama T., Nakao S., Yoshida S., Ishibashi T., Ahmadieh H., Kanavi M. R., Hafezi-Moghadam A., Penninger J. M., Sonoda K. H., Yokomizo T.
  • Journal Title: JCI Insight Volume: 3 Pages: 96902-96902
  • DOI: 10.1172/jci.insight.96902
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Applications of mass spectrometry-based targeted and non-targeted lipidomics (2018)
  • Author(s): Lee Hyeon-Cheol、Yokomizo Takehiko
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 504 Pages: 576-581
  • DOI: 10.1016/j.bbrc.2018.03.081
  • Peer Reviewed / Open Access
• [Journal Article] Biological functions of 12(S)-hydroxyheptadecatrienoic acid as a ligand of leukotriene B4 receptor 2. (2018)
  • Author(s): Okuno T., Yokomizo T.
  • Journal Title: Inflammation and Regeneration Volume: 38 Pages: 29-29
  • DOI: 10.1186/s41232-018-0087-4
  • Peer Reviewed / Open Access
• [Journal Article] Leukotriene receptors and experience as potential therapeutic targets. (2018)
  • Author(s): Yokomizo,T., Nakamura,M., and Shimizu,T
  • Journal Title: Journal of Clinical Investigation Volume: 128 Pages: 2691-2701
  • DOI: 10.1172/jci97946
  • Peer Reviewed / Open Access
• [Journal Article] 生理活性脂質ロイコトリエンB4とその受容体による免疫調節機構 (2018)
  • Author(s): 古賀友紹, 佐伯和子, 横溝岳彦
  • Journal Title: 臨床免疫・アレルギー科 Volume: 70 Pages: 209-215
• [Journal Article] 【生理活性脂質研究の最前線】 BLT2受容体の上皮保護作用 (2018)
  • Author(s): 岩本 怜., 横溝 岳彦
  • Journal Title: 炎症と免疫 Volume: 26 Pages: 380-383
• [Journal Article] 脂肪酸由来の脂質メディエーターによるアレルギー炎症の制御 (2018)
  • Author(s): 平形寿彬, 李賢喆, 横溝岳彦
  • Journal Title: 臨床免疫・アレルギー科 Volume: 69 Pages: 569-575
• [Journal Article] 【脂質クオリティ 生命機能と健康を支える脂質の多様性】 (第3章)リポクオリティによる疾患制御 ロイコトリエン受容体の生理・病態における役割 (2018)
  • Author(s): 横溝 岳彦
  • Journal Title: 実験医学 Volume: 36
• [Journal Article] Alveolar macrophages drive hepatocellular carcinoma lung metastasis by generating leukotriene B4. (2018)
  • Author(s): Nosaka T, Baba T, Tanabe Y, Sasaki S, Nishimura T, Imamura Y, Yurino H, Hashimoto S, Arita M, Nakamoto Y, Mukaida N.
  • Journal Title: J Immunol. Volume: 200 Pages: 1839-1852
  • DOI: 10.4049/jimmunol.1700544
  • Peer Reviewed / Open Access
• [Journal Article] 12-OH-17,18-Epoxyeicosatetraenoic acid alleviates eosinophilic airway inflammation in murine lungs (2018)
  • Author(s): Mochimaru T.、Fukunaga K.、Miyata J.、Matsusaka M.、Masaki K.、Kabata H.、Ueda S.、Suzuki Y.、Goto T.、Urabe D.、Inoue M.、Isobe Y.、Arita M.、Betsuyaku T.
  • Journal Title: Allergy Volume: 73 Pages: 369-378
  • DOI: 10.1111/all.13297
  • Peer Reviewed / Open Access
• [Journal Article] Stereoselective Total Synthesis of Macrophage-Produced Prohealing 14,21-Dihydroxy Docosahexaenoic Acids (2018)
  • Author(s): Nishimura Keita、Sakaguchi Tsuyoshi、Nanba Yutaro、Suganuma Yuta、Morita Masao、Hong Song、Lu Yan、Jun Bokkyoo、Bazan Nicolas G.、Arita Makoto、Kobayashi Yuichi
  • Journal Title: J Org Chem Volume: 83 Pages: 154-166
  • DOI: 10.1021/acs.joc.7b02510
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Resolvin D1 is immunoresolvent of lung inflammation caused by pseudominas aeruginosa acute and chronic infections. (2018)
  • Author(s): Codagnone M, Cianci E, Lamolinara A, Mari VC, Nespoli A, Isopi E, Mattoscio D, Arita M, Bragonzi A, Iezzi M, Romano M, Recchiuti A.
  • Journal Title: Mucosal Immunology Volume: in press Pages: 35-49
  • DOI: 10.1038/mi.2017.36
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 脂肪酸クオリティの多様性と病態（企画・編集） (2018)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ （医歯薬出版） Volume: 264
• [Journal Article] ω３脂肪酸由来脂質メディエーターと炎症制御 (2018)
  • Author(s): 吉田美桜、礒部洋輔、石原知明、有田誠
  • Journal Title: 細胞（ニューサイエンス社） Volume: 50 Pages: 8-12
• [Journal Article] Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics (2018)
  • Author(s): Lai Z, Tsugawa H, Wohlgemuth G, Mehta S, Mueller M, Zheng Y, Ogiwara A, Meissen J, Showalter M, Takeuchi K, Kind T, Beal P, Arita M, Fiehn O
  • Journal Title: Nat Methods Volume: 15 Pages: 53-56
  • DOI: 10.1038/nmeth.4512
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Leukotriene receptors as potential therapeutic target. (2018)
  • Author(s): Yokomizo, T Nakamura, M Shimizu, T
  • Journal Title: J Clin Invest Volume: -
  • Peer Reviewed
• [Journal Article] Profiling of bioactive lipids in different dendritic cell subsets using an improved multiplex quantitative LC-MS/MS method. (2018)
  • Author(s): Ohba, M Saeki, K Koga, T Okuno, T Konbayashi, Y Yokomizo, T
  • Journal Title: Biochem Biophys Res Commun Volume: -
  • Peer Reviewed
• [Journal Article] 皮膚保護作用を有する脂質メディエーター12-HHT (2018)
  • Author(s): 石井由美子 劉珉 佐伯和子 横溝岳彦
  • Journal Title: 臨床免疫・アレルギー科 Volume: 67 Pages: 106-114
  • NAID: 40021064298
• [Journal Article] The effect and possible clinical efficacy of in vivo inhibition of neutrophil extracellular traps by blockade of PI3K-gamma on the pathogenesis of microscopic polyangiitis (2018)
  • Author(s): Kimura Hirotaka、Matsuyama Yasushi、Araki Sachiko、Koizumi Atsushi、Kariya Yumi、Takasuga Shunsuke、Eguchi Satoshi、Nakanishi Hiroki、Sasaki Junko、Sasaki Takehiko
  • Journal Title: Modern Rheumatology Volume: 28 Pages: 1-12
  • DOI: 10.1080/14397595.2017.1367116
  • Peer Reviewed / Open Access
• [Journal Article] Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice (2018)
  • Author(s): Suzuki H, Nagatake T, Nasu A, Lan H, Ikegami K, Setou M, Hamazaki Y, Kiyono H, Yagi K, Kondoh M, Kunisawa J
  • Journal Title: Scientific Reports Volume: 8 Pages: 2094-2094
  • DOI: 10.1038/s41598-018-21120-7
  • NAID: 120006551757
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Profiling and Imaging of Phospholipids in Brains of Abcd1-Deficient Mice. (2018)
  • Author(s): Hama K, Fujiwara Y, Morita M, Yamazaki F, Nakashima Y, Takei S, Takashima S, Setou M, Shimozawa N, Imanaka T, Yokoyama K.
  • Journal Title: Lipids Volume: 53 Pages: 85-102
  • DOI: 10.1002/lipd.12022
  • Peer Reviewed / Open Access
• [Journal Article] Visualization of local phosphatidylcholine synthesis within hippocampal neurons using a compartmentalized culture system and imaging mass spectrometry (2018)
  • Author(s): Sugiyama Eiji、Yao Ikuko、Setou Mitsutoshi
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 495 Pages: 1048-1054
  • DOI: 10.1016/j.bbrc.2017.11.108
  • Peer Reviewed / Open Access
• [Journal Article] Imaging mass spectroscopy delineates the thinned and thickened walls of intracranial aneurysms (2018)
  • Author(s): Ikedo Taichi、Minami Manabu、Kataoka Hiroharu、Hayashi Kosuke、Nagata Manabu、Fujikawa Risako、Yamazaki Fumiyoshi、Setou Mitsutoshi、Yokode Masayuki、Miyamoto Susumu
  • Journal Title: Biochemical and Biophysical Research Communications Volume: 495 Pages: 332-338
  • DOI: 10.1016/j.bbrc.2017.10.133
  • Peer Reviewed / Open Access
• [Journal Article] Cross-talk between prostaglandin and retinoic acid signaling. (2018)
  • Author(s): Inazumi, T., and Sugimoto, Y.
  • Journal Title: Carotenoid Sci Volume: -
  • Peer Reviewed / Open Access
• [Journal Article] ゼブラフィッシュにおけるプロスタグランジンシステム (2018)
  • Author(s): 土屋創健、杉本幸彦
  • Journal Title: 生化学 Volume: 89 Pages: 445-445
  • NAID: 40021265217
  • Peer Reviewed
• [Journal Article] プロスタグランジンE2による炎症病態制御機構 (2018)
  • Author(s): 稲住知明、杉本幸彦
  • Journal Title: 細胞 Volume: 50 Pages: 118-121
• [Journal Article] Sitosterol prevents obesity-related chronic inflammation (2018)
  • Author(s): Kurano Makoto、Hasegawa Koji、Kunimi Motoei、Hara Masumi、Yatomi Yutaka、Teramoto Tamio、Tsukamoto Kazuhisa
  • Journal Title: Biochim Biophys Acta Volume: 1863 Pages: 191-198
  • DOI: 10.1016/j.bbalip.2017.12.004
  • Peer Reviewed / Open Access
• [Journal Article] Sphingosine 1-Phosphate and Atherosclerosis (2018)
  • Author(s): Kurano Makoto、Yatomi Yutaka
  • Journal Title: J Atheroscler Thromb Volume: 25 Issue: 1 Pages: 16-26
  • DOI: 10.5551/jat.rv17010 10.5551/jat.RV17010
  • NAID: 130006301107
  • ISSN: 1340-3478, 1880-3873
  • Peer Reviewed
• [Journal Article] 皮膚疾患と脂質メディエーター (2018)
  • Author(s): 本田哲也, 椛島健治
  • Journal Title: アレルギー・免疫 医薬ジャーナル社 Volume: 25 Pages: 30-37
• [Journal Article] 炎症・感染応答を担うオルガネラ (2018)
  • Author(s): 小林俊彦、向井康治朗、田口友彦、反町典子
  • Journal Title: 臨床免疫アレルギー科 Volume: 63 Pages: 99-106
• [Journal Article] Voltage-Sensing Phosphatases: Biophysics, Physiology and Engineering (2018)
  • Author(s): Okamura Y, Kawanabe A, Kawai T.
  • Journal Title: Physiological reviews Volume: -
  • Peer Reviewed
• [Journal Article] Mechanistic insight into the suppression of microglial ROS production by voltage-gated proton channels(VSOP/Hv1) (2018)
  • Author(s): Kawai T, Tatsumi S, Kihara S, Sakimura K, Okamura Y.
  • Journal Title: Channels Volume: 12 Issue: 1 Pages: 43108-43108
  • DOI: 10.1080/19336950.2017.1385684
  • Peer Reviewed / Open Access
• [Journal Article] The importance of bioinformatics for connecting data-driven lipidomics and biological insights. (2017)
  • Author(s): Tsugawa H, Ikeda K, Arita M.
  • Journal Title: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Volume: 1862 Pages: 762-765
  • DOI: 10.1016/j.bbalip.2017.05.006
  • Peer Reviewed / Open Access
• [Journal Article] Comprehensive analyses of oxidized phospholipids using a measured MS/MS spectra library (2017)
  • Author(s): Aoyagi Ryohei、Ikeda Kazutaka、Isobe Yosuke、Arita Makoto
  • Journal Title: J Lipid Res Volume: 58 Pages: 2229-2237
  • DOI: 10.1194/jlr.d077123
  • Peer Reviewed / Open Access
• [Journal Article] Gut microbiota promotes obcsity-associatcd liver cancer through PGE2-mediated suppression of antitumor immunity (2017)
  • Author(s): Loo TM, Kamachi F, Watanabe Y, Yoshimoto S, Kanda H, Arai Y, Nakajima-Takagi Y, Koga T, Sugimoto Y, Ozawa T, Nakamura M, Kumagai M, Watashi K, Taketo MM, Aoki T, Narumiya S, Oshima M, Arita M, Hara E, Ohtani N, et al.
  • Journal Title: Cancer Discovery Volume: 7 Pages: 522-538
  • DOI: 10.1158/2159-8290.cd-16-0932
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation (2017)
  • Author(s): Shimanaka Yuta、Kono Nozomu、Taketomi Yoshitaka、Arita Makoto、Okayama Yoshimichi、Tanaka Yuki、Nishito Yasumasa、Mochizuki Tatsuki、Kusuhara Hiroyuki、Adibekian Alexander、Cravatt Benjamin F、Murakami Makoto、Arai Hiroyuki
  • Journal Title: Nat Med Volume: 23 Pages: 1287-1297
  • DOI: 10.1038/nm.4417
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Hyperoxidation of ether-linked phospholipids accelerates neutrophil extracellular trap formation (2017)
  • Author(s): Yotsumoto Satoshi、Muroi Yuito、Chiba Tatsuya、Ohmura Rio、Yoneyama Maki、Magarisawa Megumi、Dodo Kosuke、Terayama Naoki、Sodeoka Mikiko、Aoyagi Ryohei、Arita Makoto、Arakawa Satoko、Shimizu Shigeomi、Tanaka Masato
  • Journal Title: Journal, Scientific Reports Volume: 7 Pages: 16026-16026
  • DOI: 10.1038/s41598-017-15668-z
  • Peer Reviewed / Open Access
• [Journal Article] Autotaxin-lysophosphatidic acid-LPA3 signaling at the embryo-epithelial boundary controls decidualization pathways (2017)
  • Author(s): Aikawa Shizu、Kano Kuniyuki、Inoue Asuka、Wang Jiao、Saigusa Daisuke、Nagamatsu Takeshi、Hirota Yasushi、Fujii Tomoyuki、Tsuchiya Soken、Taketomi Yoshitaka、Sugimoto Yukihiko、Murakami Makoto、Arita Makoto、Kurano Makoto、Ikeda Hitoshi、Yatomi Yutaka、Chun Jerold、Aoki Junken
  • Journal Title: EMBO Journal Volume: 36 Pages: 2146-2160
  • DOI: 10.15252/embj.201696290
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] リポクオリティと炎症・免疫の制御（企画・編集） (2017)
  • Author(s): 有田誠
  • Journal Title: 炎症と免疫（先端医学社） Volume: 25
• [Journal Article] 脂肪酸クオリティと炎症・アレルギーの制御 (2017)
  • Author(s): 永沼達郎、有田誠
  • Journal Title: 炎症と免疫（先端医学社） Volume: 25 Pages: 265-270
• [Journal Article] Identification of small molecules using accurate mass MS/MS search (2017)
  • Author(s): Kind T, Tsugawa H, Cajka T, Ma Y, Lai Z, Mehta SS, Wohlgemuth G, Barupal DK, Showalter MR, Arita M, Fiehn O
  • Journal Title: Mass Spectrom Rev Volume: -
  • DOI: 10.1002/mas.21535
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 化学とメタボロミクス (2017)
  • Author(s): 有田正規、津川裕司
  • Journal Title: 化学 Volume: 72 Pages: 26-30
• [Journal Article] Non-steroidal anti-inflammatory drug delays corneal wound healing by reducing production of 12-hydroxyheptadecatrienoic acid, a ligand for leukotriene B4 receptor 2 (2017)
  • Author(s): Iwamoto Satoshi、Koga Tomoaki、Ohba Mai、Okuno Toshiaki、Koike Masato、Murakami Akira、Matsuda Akira、Yokomizo Takehiko
  • Journal Title: Sci Rep Volume: 7 Pages: 1-10
  • DOI: 10.1038/s41598-017-13122-8
  • Peer Reviewed / Open Access
• [Journal Article] Identification, signaling, and functions of LTB4 receptors. (2017)
  • Author(s): Saeki K, Yokomizo T
  • Journal Title: Seminars in Immunology Volume: 33 Pages: 30-36
  • DOI: 10.1016/j.smim.2017.07.010
  • Peer Reviewed / Open Access
• [Journal Article] Biochemical and immunological characterization of a novel monoclonal antibody against mouse leukotriene B4 receptor 1. (2017)
  • Author(s): Sasaki F, Koga T, Saeki K, Okuno T, Kazuno S, Fujimura T, Ohkawa Y, Yokomizo T
  • Journal Title: PLoS One. Volume: 12 Pages: 0185133-0185133
  • DOI: 10.1371/journal.pone.0185133
  • Peer Reviewed / Open Access
• [Journal Article] Dioxin-induced increase in leukotriene B4 biosynthesis through the aryl hydrocarbon receptor and its relevance to hepatotoxicity owing to neutrophil infiltration (2017)
  • Author(s): Takeda Tomoki、Komiya Yukiko、Koga Takayuki、Ishida Takumi、Ishii Yuji、Kikuta Yasushi、Nakaya Michio、Kurose Hitoshi、Yokomizo Takehiko、Shimizu Takao、Uchi Hiroshi、Furue Masutaka、Yamada Hideyuki
  • Journal Title: J Biol Chem Volume: 292 Pages: 10586-10599
  • DOI: 10.1074/jbc.m116.764332
  • Peer Reviewed / Open Access
• [Journal Article] Vps34 regulates myofibril proteostasis to prevent hypertrophic cardiomyopathy. (2017)
  • Author(s): Kimura H, Eguchi S, Sasaki J, Kuba K, Nakanishi H, Takasuga S, Yamazaki M, Goto A, Watanabe H, Itoh H, Imai Y, Suzuki A, Mizushima N, Sasaki T
  • Journal Title: JCI insight Volume: 2(1) Pages: 89462-89478
  • DOI: 10.1172/jci.insight.89462
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Decreased 16:0/20:4-phosphatidylinositol level in the post-mortem prefrontal cortex of elderly patients with schizophrenia (2017)
  • Author(s): Matsumoto J, Nakanishi H, Kunii Y, Sugiura Y, Yuki D, Wada A, Hino M, Niwa SI, Kondo T, Waki M, Hayasaka T, Masaki N, Akatsu H, Hashizume Y, Yamamoto S, Sato S, Sasaki T, Setou M, Yabe H
  • Journal Title: Sci Rep Volume: 7 Issue: 7 Pages: 1-11
  • DOI: 10.1038/srep45050
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Lysophosphatidic acid acyltransferase 3 tunes the membrane status of germ cells by incorporating docosahexaenoic acid during spermatogenesis (2017)
  • Author(s): Iizuka-Hishikawa Yoshiko、Hishikawa Daisuke、Sasaki Junko、Takubo Keiyo、Goto Motohito、Nagata Katsuyuki、Nakanishi Hiroki、Shindou Hideo、Okamura Tadashi、Ito Chizuru、Toshimori Kiyotaka、Sasaki Takehiko、Shimizu Takao
  • Journal Title: J Biol Chem Volume: 292 Pages: 12065-12076
  • DOI: 10.1074/jbc.m117.791277
  • Peer Reviewed / Open Access
• [Journal Article] Docosahexaenoic acid preserves visual function by maintaining correct disc morphology in retinal photoreceptor cells (2017)
  • Author(s): Shindou Hideo、Koso Hideto、Sasaki Junko、Nakanishi Hiroki、Sagara Hiroshi、Nakagawa Koh M.、Takahashi Yoshikazu、Hishikawa Daisuke、Iizuka-Hishikawa Yoshiko、Tokumasu Fuyuki、Noguchi Hiroshi、Watanabe Sumiko、Sasaki Takehiko、Shimizu Takao
  • Journal Title: The Journal of Biological Chemistry Volume: 292 Pages: 1205412064-1205412064
  • DOI: 10.1074/jbc.m117.790568
  • Peer Reviewed / Open Access
• [Journal Article] PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K (2017)
  • Author(s): Malek M、Kielkowska A、Chessa T、Anderson K E.、Barneda D、Pir P、Nakanishi H、Eguchi S、Koizumi A、Sasaki J、Juvin V、Kiselev VY.、Niewczas I、Gray A、Valayer A、Spensberger D、Imbert M、Felisbino S、Habuchi T、Beinke S、Cosulich S、Le Novere N、Sasaki T、Clark J、Hawkins PT.、Stephens LR.
  • Journal Title: Mol Cell Volume: 68 Pages: 566-580
  • DOI: 10.1016/j.molcel.2017.09.024
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Fatty acid binding protein 4 enhances prostate cancer progression by upregulating matrix metalloproteinases and stromal cell cytokine production (2017)
  • Author(s): Huang Mingguo、Narita Shintaro、Inoue Takamitsu、Koizumi Atsushi、Saito Mitsuru、Tsuruta Hiroshi、Numakura Kazuyuki、Satoh Shigeru、Nanjo Hiroshi、Sasaki Takehiko、Habuchi Tomonori
  • Journal Title: Oncotarget Volume: 8 Pages: 111780-111794
  • DOI: 10.18632/oncotarget.22908
  • Peer Reviewed / Open Access
• [Journal Article] A New Electron Microscopic Method to Observe the Distribution of Phosphatidylinositol 3,4-bisphosphate (2017)
  • Author(s): Aktar S, Takatori S, Tsuji T, Orii M, Ohsaki Y, Cheng J, Fujimoto T
  • Journal Title: ACTA HISTOCHEMICA ET CYTOCHEMICA Volume: 50(5) Issue: 5 Pages: 141-147
  • DOI: 10.1267/ahc.17025
  • NAID: 130006179489
  • ISSN: 0044-5991, 1347-5800
  • Peer Reviewed / Open Access
• [Journal Article] Hepatocyte-specific depletion of ubiquitin regulatory X domain containing protein 8 accelerates fibrosis in a mouse non-alcoholic steatohepatitis model (2017)
  • Author(s): Imai Norihiro、Suzuki Michitaka、Ishizu Yoji、Kuzuya Teiji、Honda Takashi、Hayashi Kazuhiko、Ishigami Masatoshi、Hirooka Yoshiki、Ishikawa Tetsuya、Goto Hidemi、Fujimoto Toyoshi
  • Journal Title: Histochem Cell Biol Volume: 148 Pages: 219-227
  • DOI: 10.1007/s00418-017-1572-6
  • Peer Reviewed
• [Journal Article] Evidence for ESCRT- and clathrin-dependent microautophagy. (2017)
  • Author(s): Masahide Oku, Yuichiro Maeda, Yoko Kagohashi, Takeshi Kondo, Mai Yamada, Toyoshi Fujimoto, Yasuyoshi Sakai
  • Journal Title: The Journal of Cell Biology Volume: 216 Pages: 3263-3274
  • DOI: 10.1083/jcb.201611029
  • NAID: 120006454716
  • Peer Reviewed
• [Journal Article] Niemann-Pick type C proteins promote microautophagy by expanding raft-like membrane domains in the yeast vacuole (2017)
  • Author(s): Tsuji T, Fujimoto M, Tatematsu T, Cheng J, Orii M, Takatori S, Fujimoto T
  • Journal Title: eLife Volume: 6
  • DOI: 10.7554/elife.25960
  • Peer Reviewed / Open Access
• [Journal Article] Freeze-fracture-etching Electron Microscopy for Facile Analysis of Yeast Ultrastructure (2017)
  • Author(s): Tsuji Takuma、Fujimoto Toyoshi
  • Journal Title: BIO-PROTOCOL Volume: 7
  • DOI: 10.21769/bioprotoc.2556
  • Peer Reviewed / Open Access
• [Journal Article] The lipid droplet and the endoplasmic reticulum (2017)
  • Author(s): Ohsaki, Y., Soltysik, K., and Fujimoto, T
  • Journal Title: Adv Exp Med Biol Volume: 997 Pages: 111-120
• [Journal Article] Hepatic S6K1 Partially Regulates Lifespan of Mice with Mitochondrial Complex I Deficiency (2017)
  • Author(s): Ito TK, Lu C, Khan J, Nguyen Q, Huang HZ, Kim D, Phillips J, Tan J, Lee Y, Nguyen T, Khessib S, Lim N, Mekvanich S, Oh J, Pineda VV, Wang W, Bitto A, An JY, Morton JF, Setou M, Ladiges WC, Kaeberlein M.
  • Journal Title: Frontiers in Genetics Volume: 8 Pages: 113-113
  • DOI: 10.3389/fgene.2017.00113
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Recurrent triple-negative breast cancer (TNBC) tissues contain a higher amount of phosphatidylcholine (32:1) than non-recurrent TNBC tissues (2017)
  • Author(s): Hosokawa Yuko、Masaki Noritaka、Takei Shiro、Horikawa Makoto、Matsushita Shoko、Sugiyama Eiji、Ogura Hiroyuki、Shiiya Norihiko、Setou Mitsutoshi
  • Journal Title: PLOS ONE Volume: 12
  • DOI: 10.1371/journal.pone.0183724
  • Peer Reviewed / Open Access
• [Journal Article] Immunohistochemical expression analysis of leucine-rich PPR-motif-containing protein (LRPPRC), a candidate colorectal cancer biomarker identified by shotgun proteomics using iTRAQ (2017)
  • Author(s): Nishio Tomohisa、Kurabe Nobuya、Goto-Inoue Naoko、Nakamura Toshio、Sugimura Haruhiko、Setou Mitsutoshi、Maekawa Masato
  • Journal Title: Clinica Chimica Acta Volume: 471 Pages: 276-282
  • DOI: 10.1016/j.cca.2017.06.011
  • Peer Reviewed / Open Access
• [Journal Article] Enantioselective inhibitory abilities of enantiomers of notoamides against RANKL-induced formation of multinuclear osteoclasts (2017)
  • Author(s): Kato Hikaru、Kai Aika、Kawabata Tetsuro、Sunderhaus James D.、McAfoos Timothy J.、Finefield Jennifer M.、Sugimoto Yukihiko、Williams Robert M.、Tsukamoto Sachiko
  • Journal Title: Bioorg. Med. Chem. Lett. Volume: 27 Pages: 4975-4978
  • DOI: 10.1016/j.bmcl.2017.10.017
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] An aromatic amino acid within intracellular loop 2 of the prostaglandin EP2 receptor is a prerequisite for selective association and activation of Gαs. (2017)
  • Author(s): Yano A, Takahashi Y, Moriguchi H, Inazumi T, Koga T, Otaka A, Sugimoto Y.
  • Journal Title: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Volume: 1862 Pages: 615-622
  • DOI: 10.1016/j.bbalip.2017.03.006
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 雌性生殖生理におけるプロスタグランジン受容体の役割 (2017)
  • Author(s): 杉本幸彦
  • Journal Title: 別冊BIO Clinica 慢性炎症と疾患 Volume: 6 Pages: 16-21
• [Journal Article] Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes (2017)
  • Author(s): Kurano M, Nishikawa M, Kuma H, Jona M, Yatomi Y.
  • Journal Title: PLos One Volume: 12
  • DOI: 10.1371/journal.pone.0177543
  • Peer Reviewed / Open Access
• [Journal Article] High fat diet exacerbates murine psoriatic dermatitis by increasing the number of IL-17-producing γδ T cells (2017)
  • Author(s): Nakamizo Satoshi、Honda Tetsuya、Adachi Akimasa、Nagatake Takahiro、Kunisawa Jun、Kitoh Akihiko、Otsuka Atsushi、Dainichi Teruki、Nomura Takashi、Ginhoux Florent、Ikuta Koichi、Egawa Gyohei、Kabashima Kenji
  • Journal Title: Sci. Rep. Volume: 7 Pages: 14076-14076
  • DOI: 10.1038/s41598-017-14292-1
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Advances in atopic dermatitis and urticarial in 2016 (2017)
  • Author(s): Honda Tetsuya、Nomura Takashi、Kabashima Kenji
  • Journal Title: Journal of Allergy and Clinical Immunology Volume: 140 Pages: 369-376
  • DOI: 10.1016/j.jaci.2017.06.005
• [Journal Article] Lysosome biogenesis regulated by the amino-acid transporter SLC15A4 is critical for functional integrity of mast cells (2017)
  • Author(s): Kobayashi Toshihiko、Tsutsui Hidemitsu、Shimabukuro-Demoto Shiho、Yoshida-Sugitani Reiko、Karyu Hitomi、Furuyama-Tanaka Kaori、Ohshima Daisuke、Kato Norihiro、Okamura Tadashi、Toyama-Sorimachi Noriko
  • Journal Title: Int Immunol. Volume: 29 Pages: 551-566
  • DOI: 10.1093/intimm/dxx063
  • Peer Reviewed / Open Access
• [Journal Article] A novel role for PHT1 in the disposition of l-histidine in brain: In vitro slice and in vivo pharmacokinetic studies in wildtype and Pht1 null mice. (2017)
  • Author(s): Wang XX, Hu Y, Keep RF, Toyama-Sorimachi N, Smith DE.
  • Journal Title: Biochemical Pharmacology Volume: 15 Pages: 94-102
  • DOI: 10.1016/j.bcp.2016.11.012
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 炎症抑制に関わる電位依存性プロトンチャネルHv1/VSOPの機能（リポクオリティによる膜タンパク質の機能制御と炎症・免疫） (2017)
  • Author(s): 大河内善史、川鍋陽、岡村康司
  • Journal Title: 炎症と免疫 2017年7月号 Volume: 25 Pages: 17-22
  • Peer Reviewed
• [Journal Article] Domain-to-domain coupling in voltage-sensing phosphatase (2017)
  • Author(s): Sakata S, Matsuda M, Kawanabe A, Okamura Y.
  • Journal Title: BIOPHYSICS Volume: 1 Issue: 0 Pages: 85-97
  • DOI: 10.2142/biophysico.14.0_85
  • NAID: 130007041363
  • ISSN: 2189-4779
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Unconventional role of voltage-gated proton channels (VSOP/Hv1) in regulation of microglial ROS production. (2017)
  • Author(s): Kawai T, Okochi Y, Ozaki T, Imura Y, Koizumi S, Yamazaki M, Abe M, Sakimura K, Yamashita T, Okamura Y.
  • Journal Title: J Neurochem. Volume: 142 Issue: 5 Pages: 686-699
  • DOI: 10.1111/jnc.14106
  • Peer Reviewed / Open Access
• [Journal Article] Molecular and functional characterization of the voltage-gated proton channel in zebrafish neutrophils (2017)
  • Author(s): Ratanayotha Adisorn、Kawai Takafumi、Higashijima Shin-ichi、Okamura Yasushi
  • Journal Title: Physiol Rep Volume: 5
  • DOI: 10.14814/phy2.13345
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] 電位センサードメインを用いた膜電位プローブの進歩 (2017)
  • Author(s): 河合 喬文、筒井 秀和、岡村 康司
  • Journal Title: 生体の科学 Volume: 68 Issue: 5 Pages: 444-445
  • DOI: 10.11477/mf.2425200686
  • ISSN: 0370-9531, 1883-5503
  • Peer Reviewed
• [Journal Article] Comprehensive identification of sphingolipid species by in silico retention time and tandem mass spectral library. (2017)
  • Author(s): Tsugawa H, Ikeda K, Tanaka W, Senoo Y, Arita M, Arita M.
  • Journal Title: Journal of cheminformatics Volume: 9 Pages: 19-19
  • DOI: 10.1186/s13321-017-0205-3
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] PNPLA1 has a crucial role in skin barrier function by directing acylceramide biosynthesis. (2017)
  • Author(s): Hirabayashi T, Anjo T, Kaneko A, Senoo Y, Shibata A, Takama H, Yokoyama K, Nishito Y, Ono T, Taya C, Muramatsu K, Fukami K, Mu&ntilde;oz-Garcia A, Brash A, Ikeda K, Arita M, Akiyama M, Murakami M.
  • Journal Title: Nat. Commun. Volume: 8 Pages: 14609-14609
  • DOI: 10.1038/ncomms14609
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] ω３脂肪酸の代謝と抗炎症作用に関する研究 (2017)
  • Author(s): 有田誠
  • Journal Title: 脂質栄養学（日本脂質栄養学会） Volume: 26 Pages: 27-34
  • NAID: 130006894081
  • Peer Reviewed
• [Journal Article] Different desmin peptides are distinctly deposited in cytoplasmic aggregations and cytoplasm of desmin-related cardiomyopathy patients. (2017)
  • Author(s): Shintani-Domoto Y, Hayasaka T, Maeda D, Masaki N, Ito TK, Sakuma K, Tanaka M, Kabashima K, Takei S, Setou M, Fukayama M.
  • Journal Title: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics Volume: S1570-9639 Pages: 30048-1
  • DOI: 10.1016/j.bbapap.2017.03.006
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Minos-insertion mutant of the Drosophila GBA gene homologue showed abnormal phenotypes of climbing ability, sleep and life span with accumulation of hydroxy-glucocerebroside. (2017)
  • Author(s): Kawasaki H, Suzuki T, Ito K, Takahara T, Goto-Inoue N, Setou M, Sakata K, Ishida N.
  • Journal Title: Gene. Volume: S0378-1119 Pages: 30139-7
  • DOI: 10.1016/j.gene.2017.03.004
  • Peer Reviewed / Open Access
• [Journal Article] Proper cytoskeletal architecture beneath the plasma membrane of red blood cells requires Ttll4. (2017)
  • Author(s): Ijaz F, Hatanaka Y, Hatanaka T, Tsutsumi K, Iwaki T, Umemura K, Ikegami K, Setou M.
  • Journal Title: Mol Biol Cell. Volume: 28 Pages: 535-544
  • DOI: 10.1091/mbc.e16-02-0089
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Selective improvement of peptides imaging on tissue by supercritical fluid wash of lipids for matrix-assisted laser desorption/ionization mass spectrometry. (2017)
  • Author(s): Matsushita S, Masaki N, Sato K, Hayasaka T, Sugiyama E, Hui SP, Chiba H, Mase N, Setou M.
  • Journal Title: Anal. Bioanal. Chem. Volume: 409 Pages: 1475-1475
  • DOI: 10.1007/s00216-016-0119-3
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Dynamic Remodeling of Membrane Composition Drives Cell Cycle through Primary Cilia Excision (2017)
  • Author(s): Phua SC, Chiba S, Suzuki M, Su E, Roberson EC, Pusapati GV, Setou M, Rohatgi R, Reiter JF, Ikegami K, Inoue T
  • Journal Title: Cell Volume: 168 Pages: 264-279
  • DOI: 10.1016/j.cell.2016.12.032
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] The lipid droplet and the endoplasmic reticulum (2017)
  • Author(s): Ohsaki Y, Soltysik K, Fujimoto T
  • Journal Title: Advances in Experimental Medicine and Biology Volume: 997 Pages: 121-133
  • DOI: 10.1007/978-981-10-4567-7
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] 電子顕微鏡による脂肪滴と膜脂質の探索 (2017)
  • Author(s): 藤本豊士、大﨑雄樹、辻琢磨
  • Journal Title: Proc. Clin. Electron Microsc Volume: 35 Pages: 1-3
• [Journal Article] Interleaflet coupling, pinning and leaflet asymmetry- major players in plasma membrane nanodomain formation (2017)
  • Author(s): Fujimoto T, Parmryd I
  • Journal Title: Frontier Cell Dev Biol Volume: 4 Pages: 155-155
  • DOI: 10.3389/fcell.2016.00155
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging. (2017)
  • Author(s): Inagaki S, Tsutsui H, Suzuki K, Agetsuma M, Arai Y, Jinno Y, Bai G, Daniels M, Okamura Y, Matsuda M, and Nagai T
  • Journal Title: Scientific Report Volume: 7 Pages: 42398-42398
  • DOI: 10.1038/srep42398
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] AMPA glutamate receptors are required for sensory-organ formation and morphogenesis in the basal chordate (2017)
  • Author(s): Shinobu Hirai, Kohji Hotta, Yoshihiro Kubo, Atsuo Nishino, Shigeo Okabe, Yasushi Okamura, Haruo Okado
  • Journal Title: PNAS Volume: in press
  • Peer Reviewed / Open Access
• [Journal Article] Domain-to-domain coupling in voltage-sensing phosphatase (2017)
  • Author(s): Souhei Sakata, Makoto Matsuda, Akira Kawanabe, Yasushi Okamura
  • Journal Title: Biophysics and Physiobiology Volume: in press
  • Peer Reviewed / Open Access
• [Journal Article] 炎症抑制に関わる電位依存性プロトンチャネルHv1/VSOPの機能（リポクオリティによる膜タンパク質の機能制御と炎症・免疫 (2017)
  • Author(s): 大河内善史、川鍋陽、岡村康司
  • Journal Title: 炎症と免疫 Volume: in press
• [Journal Article] Analysis of glycero-lysophospholipids in gastric cancerous ascites. (2017)
  • Author(s): Emoto, S., Kurano, M., Kano, K., Matsusaki, K., Yamashita, H., Nishikawa, M., Igarashi, K., Ikeda, H., Aoki, J., Kitayama, J., and Yatomi, Y.
  • Journal Title: Journal of Lipid Research Volume: 58 Pages: 763-771
  • DOI: 10.1194/jlr.p072090
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Involvement of Cholesteryl Ester Transfer Protein in the Shift of Sphingosine 1-Phosphate Among Lipoproteins and in the Modulation of its Functions. (2017)
  • Author(s): Kurano, M., Hara, M., Ikeda, H., Tsukamoto, K., and Yatomi, Y
  • Journal Title: Arterioscler Thromb Vasc Biol. Volume: 37 Pages: 506-514
  • DOI: 10.1161/atvbaha.116.308692
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Different Origins of Lysophospholipid Mediators between Coronary and Peripheral Arteries in Acute Coronary Syndrome. (2017)
  • Author(s): Kurano, M., Kano, K., Dohi, T., Matsumoto, H., Igarashi, K., Nishikawa, M., Ohkawa, R., Ikeda, H., Miyauchi, K., Daida, H., Aoki, J., and Yatomi, Y.
  • Journal Title: J Lipid Res. Volume: 58 Pages: 433-442
  • DOI: 10.1194/jlr.p071803
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Vehicle-dependent Effects of Sphingosine 1-phosphate on Plasminogen Activator Inhibitor-1 Expression (2017)
  • Author(s): Takahashi, C., Kurano, M., Nishikawa, M., Kano, K., Dohi, T., Miyauchi, K., Daida, H., Shimizu, T., Aoki, J., and Yatomi, Y.
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  • NAID: 130006038432
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  • Author(s): Shigematsu, M., Koga, T., Ishimori, A., Saeki, K., Ishii, Y., Taketomi, Y., Ohba, M., Jo-Watanabe, A., Okuno, T., Harada, N., Harayama, T., Shindou, H., Li, J. D., Murakami, M., Hoka, S.,Yokomizo, T.
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  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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  • Author(s): Koutsogiannaki, S., Schaefers, M. M., Okuno, T., Ohba, M., Yokomizo, T., Priebe, G. P., DiNardo, J. A., Sulpicio, S. G.,Yuki, K.
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  • DOI: 10.1093/toxsci/kfw261
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• [Journal Article] A synthetic leukotriene B4 receptor type 2 agonist accelerates the cutaneous wound healing process in diabetic rats by indirect stimulation of fibroblasts and direct stimulation of keratinocytes (2017)
  • Author(s): Luo, L., Tanaka, R., Kanazawa, S., Lu, F., Hayashi, A., Yokomizo, T.,Mizuno, H.
  • Journal Title: Journal of Diabetes and its Complications Volume: 31 Pages: 13-20
  • DOI: 10.1016/j.jdiacomp.2016.09.002
  • Peer Reviewed / Open Access
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  • Author(s): Okuno, T., Koutsogiannaki, S., Ohba, M., Chamberlain, M., Bu, W., Lin, F. Y., Eckenhoff, R. G., Yokomizo, T.,Yuki, K.
  • Journal Title: The FASEB Journal Volume: 31 Pages: 1584-1594
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  • Journal Title: 臨床免疫・アレルギー科 Volume: 67 Pages: 106-114
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• [Journal Article] Eosinophil polyunsaturated fatty acid metabolism and its potential control of inflammation and allergy. (2016)
  • Author(s): Arita M
  • Journal Title: Allergol Int Volume: 65
  • DOI: 10.1016/j.alit.2016.05.010
  • NAID: 130005418951
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• [Journal Article] Hydrogen Rearrangement Rules: Computational MS/MS Fragmentation and Structure Elucidation Using MS-FINDER Software (2016)
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  • Journal Title: Analytical Chemistry Volume: 88 Pages: 7946-7958
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• [Journal Article] Editorial: Metabolome Informatics and Statistics: Current State and Emerging Trends (2016)
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  • Peer Reviewed / Open Access / Int'l Joint Research
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  • Author(s): 津川裕司、有田正規
  • Journal Title: 化学と生物 Volume: 54 Pages: 151-153
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  • Author(s): 有田誠
  • Journal Title: 血管医学（メディカルレビュー社） Volume: 17 Pages: 115-117
• [Journal Article] 脂肪酸クオリティ制御と血管医学 (2016)
  • Author(s): 遠藤仁、有田誠
  • Journal Title: 血管医学（メディカルレビュー社） Volume: 17 Pages: 137-143
• [Journal Article] リピドミクスによる脂肪酸代謝と疾患制御の解析 (2016)
  • Author(s): 有田誠
  • Journal Title: 生体の科学（医学書院） Volume: 67 Pages: 189-192
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  • Journal Title: Innate Immun Volume: 6 Pages: 444-444
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• [Journal Article] イノシトールリン脂質のがん転移への関与 : "invadopodia"の形成機構 (2016)
  • Author(s): 坂東 倫行、佐々木 雄彦
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  • Journal Title: AVD Volume: 9 Issue: 4 Pages: 277-284
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• [Journal Article] Visualization of sphingolipids and phospholipids in the fundic gland mucosa of human stomach using imaging mass spectrometry. (2016)
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• [Journal Article] Protease-resistant modified human β-hexosaminidase B ameliorates symptoms in GM2 gangliosidosis model. (2016)
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• [Journal Article] Imaging mass spectrometry detects dynamic changes of phosphatidylcholine in rat hippocampal CA1 after transient global ischemia. (2016)
  • Author(s): Miyawaki S, Imai H, Hayasaka T, Masaki N, Ono H, Ochi T, Ito A, Nakatomi H, Setou M, Saito N.
  • Journal Title: Neuroscience Volume: 322 Pages: 66-77
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• [Journal Article] 質量顕微鏡法の開発とその応用 (2016)
  • Author(s): 瀬藤光利
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  • NAID: 130005421348
• [Journal Article] 脂質分解イメージングで脂質を"見る" (2016)
  • Author(s): 堀川誠、武井史郎、瀬藤光利
  • Journal Title: 生体の科学 Volume: 67 Pages: 198-202
• [Journal Article] Acute accumulation of free cholesterol induces the degradation of perilipin 2 and Rab18-dependent fusion of ER and lipid droplets in cultured human hepatocytes. (2016)
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  • Journal Title: Mol. Biol. Cell Volume: 27 Pages: 3293-3304
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  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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  • Journal Title: Biochim. Biophys. Acta Volume: 1858 Pages: 2972-2983
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  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Voltage-dependent motion of the catalytic region of voltage-sensing phosphatase monitored by a fluorescent amino acid (2016)
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• [Journal Article] Simple scheme of lipid enzyme can explain complex lives of phosphoinositides. (2016)
  • Author(s): Okamura Y.
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• [Journal Article] 細胞膜の機能的区画化におけるクラスターとドメインの概念とその制御 (2016)
  • Author(s): 反町典子
  • Journal Title: 生体の科学 特集号「脂質ワールド」 Volume: 67 Pages: 220-226
• [Journal Article] Resveratrol exerts a biphasic effect on apolipoprotein M. (2016)
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• [Journal Article] Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence. (2016)
  • Author(s): Uranbileg B, Ikeda H, Kurano M, Enooku K, Sato M, Saigusa D, Aoki J, Ishizawa T, Hasegawa K, Kokudo N, Yatomi Y.
  • Journal Title: PLOS ONE Volume: 11
  • DOI: 10.1371/journal.pone.0149462
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Higher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin Levels. (2016)
  • Author(s): Enooku K, Uranbileg B, Ikeda H, Kurano M, Sato M, Kudo H, Maki H, Koike K, Hasegawa K, Kokudo N, Yatomi Y.
  • Journal Title: PLoS One Volume: 11
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  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Regulation of the lysophosphatidylserine and sphingosine 1-phosphate levels in autologous whole blood by the pre-storage leukocyte reduction (2016)
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  • Journal Title: Transfus Med Volume: 26 Pages: 365-372
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• [Journal Article] Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human. (2016)
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• [Journal Article] 肝疾患による二次性脂質異常症． (2016)
  • Author(s): 蔵野 信．
  • Journal Title: 臨床病理 Volume: 64 Pages: 518-526
• [Journal Article] 急性冠症候群の病態生理におけるマイナーリゾリン脂質の関与の可能性． (2016)
  • Author(s): 蔵野 信．
  • Journal Title: 日本血栓止血学会誌 Volume: 27 Pages: 460-465
• [Journal Article] HDLの抗血栓作用． (2016)
  • Author(s): 蔵野 信．
  • Journal Title: 臨床病理 Volume: 64 Pages: 66-71
• [Journal Article] スフィンゴシン1－リン酸とHDL． (2016)
  • Author(s): 蔵野 信，矢冨 裕.
  • Journal Title: 医学のあゆみ Volume: 259 Pages: 878-879
• [Journal Article] The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes (2016)
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  • Journal Title: Exp Dermatol Volume: 25 Pages: 532-536
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• [Journal Article] Modulation of leukotriene B4 receptor 1 signaling by receptor for advanced glycation end products, RAGE. (2016)
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• [Journal Article] Receptor for Advanced Glycation End Products Regulates Leukotriene B4 Receptor 1 Signaling (2016)
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  • Journal Title: DNA and Cell Biology Volume: 35 Pages: 747-750
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• [Journal Article] Leukotriene B4 receptor type 2 (BLT2) enhances skin barrier function by regulating tight junction proteins. (2016)
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• [Journal Article] BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils (2016)
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• [Journal Article] CD10-Equipped Melanoma Cells Acquire Highly Potent Tumorigenic Activity: A Plausible Explanation of Their Significance for a Poor Prognosis (2016)
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  • Journal Title: PLoS One Volume: 11
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• [Journal Article] Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells (2016)
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• [Journal Article] 【脂質ワールド】 新規脂質メディエーターと受容体 古くて新しい脂質メディエーター・12-ヒドロキシヘプタデカトリエン酸の生理作用 (2016)
  • Author(s): 横溝岳彦
  • Journal Title: 生体の科学 Volume: 67 Pages: 232-236
• [Journal Article] 快人快説 最先端の研究テクノロジー紹介 微量サンプル中の微量脂質を定量化する驚異の質量分析技術 (2016)
  • Author(s): 横溝岳彦
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• [Journal Article] 「脂質マシナリー」研究 脂質メディエーターの最新の研究成果 (2016)
  • Author(s): 横溝岳彦
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• [Journal Article] Olfactory receptor for prostaglandin F2α mediates male fish courtship behavior. (2016)
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• [Journal Article] Prostaglandin D2 elicits the reversible neurite retraction in hypothalamic cell line. (2016)
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• [Journal Article] プロスタノイド受容体を介した免疫・炎症応答亢進の分子機構 (2016)
  • Author(s): 告恭史郎、杉本幸彦
  • Journal Title: 医学のあゆみ Volume: 256 Pages: 561-566
• [Journal Article] プロスタノイドクオリティと心血管系制御」血管医学 (2016)
  • Author(s): 告恭史郎、稲住知明、杉本幸彦
  • Journal Title: 血管医学 Volume: 17 Pages: 37-43
• [Journal Article] Maternal dietary imbalance between omega-6 and omega-3 polyunsaturated fatty acids impairs neocortical development via epoxy metabolites. (2016)
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  • Journal Title: Stem Cells Volume: 34(2) Pages: 470-482
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• [Journal Article] 脂肪酸クオリティによる炎症性疾患の制御 (2016)
  • Author(s): 有田誠
  • Journal Title: 感染炎症免疫 Volume: 46 Pages: 22-30
• [Journal Article] Imaging Mass Spectrometry Reveals a Unique Distribution of Triglycerides in the Abdominal Aortic Aneurysmal Wall. (2016)
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• [Journal Article] A novel organ culture model of aorta for vascular calcification. (2016)
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  • Journal Title: Atherosclerosis Volume: 244 Pages: 51-58
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  • Peer Reviewed
• [Journal Article] Characteristic Distribution Pattern of Lysophosphatidylcholine in Fibromuscular Dysplasia-Associated Visceral Artery Aneurysms Compared with Atherosclerotic Visceral Artery Aneurysms. (2016)
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• [Journal Article] Imaging mass spectrometry detects dynamic changes of phosphatidylcholine in rat hippocampal CA1 after transient global ischemia (2016)
  • Author(s): Miyawaki S, Imai H, Hayasaka T, Masaki N, Ono H, Ochi T, Ito A, Nakatomi H, Setou M, Saito.
  • Journal Title: Neuroscience Volume: 印刷中
  • Peer Reviewed
• [Journal Article] 質量顕微鏡の原理とその応用 (2016)
  • Author(s): 佐野圭吾、深野華、有久亘、瀬藤光利
  • Journal Title: 病理と臨床&nbsp; Volume: 34 Pages: 203-210
• [Journal Article] 脂質分析イメージングで脂質を「見る」 (2016)
  • Author(s): 堀川誠、武井史郎、瀬藤光利
  • Journal Title: 生体の科学 Volume: 印刷中
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  • Author(s): Kawanabe A., Okamura Y.
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• [Journal Article] The voltage-gated proton channel Hv1/VSOP inhibits neutrophil granule release (2016)
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  • Author(s): 岡村康司
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  • NAID: 130005121653
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  • Journal Title: Exp Cell Res Volume: 342 Pages: 1-10
  • DOI: 10.1016/j.yexcr.2016.02.011
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• [Journal Article] The leukotriene B4 receptor BLT2 protects barrier function via actin polymerization with phosphorylation of myosin phosphatase target subunit 1 in human keratinocytes. (2016)
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  • Journal Title: Exp Dermatol I Volume: 印刷中
  • Peer Reviewed
• [Journal Article] ロイコトリエン受容体 (2016)
  • Author(s): 市木貴子, 古賀友紹, 横溝岳彦.
  • Journal Title: 医学のあゆみ Volume: 256 Pages: 554-560
  • NAID: 10025740562
• [Journal Article] Olfactory receptor for prostaglandin F2α mediates male fish courtship behavior. (2016)
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• [Journal Article] プロスタノイド受容体を介した免疫・炎症応答亢進の分子機構 (2016)
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  • Journal Title: 医学のあゆみ Volume: 256(5) Pages: 561-566
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  • Journal Title: PLoS One Volume: 10
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  • DOI: 10.1084/jem.20150381
  • NAID: 120005733188
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  • Journal Title: Intern. Med. Volume: 54 Issue: 18 Pages: 2377-2382
  • DOI: 10.2169/internalmedicine.54.4623
  • NAID: 130005099678
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• [Journal Article] Neurite outgrowth stimulation by n3 and n6 polyunsaturated fatty acids of phospholipids in apolipoprotein E containing lipoproteins secreted from glial cells. (2015)
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• [Journal Article] Total synthesis of four stereoisomers of (4Z,7Z,10Z,12E,16Z,18E)-14,20-dihydroxy-4,7,10,12,16,18-docosahexaenoic acid and their anti-inflammatory activities. (2015)
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  • Journal Title: J. Org. Chem, Volume: 80 Pages: 7713-7726
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• [Journal Article] Eosinophil-mediated signaling attenuates inflammatory responses in experimental colitis. (2015)
  • Author(s): Masterson JC, McNamee EN, Fillon SA, Hosford L, Harris R, Fernando SD, Jedlicka P, Iwamoto R, Jacobsen E, Protheroe C, Eltzschig HK, Colgan SP, Arita M, Lee JJ, Furuta GT.
  • Journal Title: Gut Volume: 64 Pages: 1236-1247
  • DOI: 10.1136/gutjnl-2014-306998
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• [Journal Article] MS-DIAL: data-independent MS/MS deconvolution for comprehensive metabolome analysis. (2015)
  • Author(s): Hiroshi Tsugawa, Tomas Cajka, Tobias Kind, Yan Ma, Brendan Higgins, Kazutaka Ikeda, Mitsuhiro Kanazawa, Jean VanderGheynst, Oliver Fiehn, Masanori Arita
  • Journal Title: Nat Methods Volume: 12 Pages: 523-526
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• [Journal Article] ω３脂肪酸の分子栄養学 (2015)
  • Author(s): 有田誠
  • Journal Title: アンチエイジング医学（メディカルレビュー社） Volume: 11 Pages: 845-851
  • NAID: 40020717239
• [Journal Article] ω３脂肪酸のメタボローム解析と心臓リモデリング抑制作用 (2015)
  • Author(s): 有田誠
  • Journal Title: 内分泌・糖尿病・代謝内科（科学評論社） Volume: 41 Pages: 380-384
  • NAID: 40020676046
• [Journal Article] 多価不飽和脂肪酸の代謝と炎症の制御 (2015)
  • Author(s): 有田誠
  • Journal Title: 医学のあゆみ（医歯薬出版） Volume: 254 Pages: 1127-1130
• [Journal Article] ω３脂肪酸の代謝と疾患制御のメタボロミクス (2015)
  • Author(s): 有田誠
  • Journal Title: 実験医学増刊号「脂質疾患学」（羊土社） Volume: 33 Pages: 2361-2366
• [Journal Article] 炎症の収束に関わる脂肪酸代謝系とその機能 (2015)
  • Author(s): 有田誠
  • Journal Title: 別冊BIO Clinica「慢性炎症と疾患」（北隆館） Volume: 4 Pages: 27-31
• [Journal Article] 脂肪酸代謝と炎症のメタボロミクス (2015)
  • Author(s): 有田誠
  • Journal Title: 臨床免疫・アレルギー科（科学評論社） Volume: 63 Pages: 118-124
• [Journal Article] ω３脂肪酸の代謝と心臓保護作用 (2015)
  • Author(s): 有田誠
  • Journal Title: 別冊BIO Clinica「慢性炎症と疾患」（北隆館） Volume: 4 Pages: 99-110
• [Journal Article] ω３系多価不飽和脂肪酸による心臓リモデリング抑制 (2015)
  • Author(s): 有田誠、遠藤仁
  • Journal Title: 循環plus（メディカルトリビューン社） Volume: 15 Pages: 7-9
• [Journal Article] Loss of INPP4B causes a DNA repair defect through loss of BRCA1, ATM and ATR and can be targeted with PARP inhibitor treatment. (2015)
  • Author(s): Ip, LR., Poulogiannis, G., Viciano, FC., Sasaki, J., Kofuji, S., Spanswick, VJ., Hochhauser, D., Hartley, JA., Sasaki, T., Gewinner, CA.
  • Journal Title: Oncotarget Volume: 6 Pages: 10548-10562
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• [Journal Article] INPP4B Is a PtdIns (3,4,5) P3 Phosphatase That Can Act as a Tumor Suppressor. (2015)
  • Author(s): Kofuji, S., Kimura, H., Nakanishi, H., Nanjo, H., Takasuga, S., Liu, H., Eguchi, S., Nakamura, R., Itoh, R., Ueno, N., Asanuma, K., Huang, M., Koizumi, A., Habuchi, T., Yamazaki, M., Suzuki, A., Sasaki, J., Sasaki, T.
  • Journal Title: Cancer Discov. Volume: 5 Pages: 730-739
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• [Journal Article] Inositol Polyphosphate-4-Phosphatase Type I Negatively (2015)
  • Author(s): Nigorikawa, K., Hazeki, K., Sasaki, J., Omori, Y., Miyake, M., Morioka, S., Guo, Y., Sasaki, T., Hazeki, O
  • Journal Title: Cancer Discov. Volume: 10 Pages: 740-751
  • DOI: 10.1371/journal.pone.0142091
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• [Journal Article] The ML1Nx2 Phosphatidylinositol 3,5-Bisphosphate Probe Shows Poor Selectivity in Cells. (2015)
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  • Journal Title: PLoS One Volume: 10
  • DOI: 10.1371/journal.pone.0139957
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Localizing the lipid products of PI3Kγ in neutrophils (2015)
  • Author(s): Norton L, Lindsay Y, Deladeriere A, Chessa T, Guillou H, Suire S, Lucocq J, Walker S, Andrews S, Segonds-Pichon A, Rausch O, Finan P, Sasaki T, Du CJ, Bretschneider T, Ferguson GJ, Hawkins PT, Stephens L.
  • Journal Title: Adv Biol Regul Volume: 60 Pages: 36-45
  • DOI: 10.1016/j.jbior.2015.10.005
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] INPP4BはPTEN欠損による発がんへのフェイルセーフ機構を担う (2015)
  • Author(s): 小藤智史，佐々木雄彦
  • Journal Title: 実験医学 Volume: 34 Pages: 450-453
• [Journal Article] Reductions of docosahexaenoic acid-containing phosphatidylcholine levels in the anterior horn of an ALS mouse model. (2015)
  • Author(s): Arima H, Omura T, Hayasaka T, Masaki N, Hanada M, Xu D, Banno T, Kobayashi K, Takeuchi H, Kadomatsu K, Matsuyama Y, Setou M.
  • Journal Title: Neuroscience Volume: 印刷中 Pages: 127-136
  • DOI: 10.1016/j.neuroscience.2015.03.060
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Decreased level of phosphatidylcholine (16:0/20:4) in multiple myeloma cells compared to plasma cells: A single-cell MALDI-IMS approach. (2015)
  • Author(s): Hossen A, Nagata Y, Waki M, Ide Y, Takei S, Fukano H, Romero-Perez GA, Tajima S, Yao I, Ohnishi K,Setou M.
  • Journal Title: Anal Bioanal Chem. Volume: 407 Pages: 5273-5280
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  • Author(s): Masaki N, Ishizaki I, Hayasaka T, Fisher GL, Sanada N, Yokota H, Setou M.
  • Journal Title: Sci Rep. Volume: 5 Pages: 10000-10000
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• [Journal Article] Variation of prostaglandin E2 concentrations in ovaries and its effects on ovarian maturation and oocyte proliferation in the giant fresh water prawn, Macrobrachium rosenbergii. (2015)
  • Author(s): Sumpownon C, Engsusophon A, Siangcham T, Sugiyama E, Soonklang N, Meeratana P, Wanichanon C, Hanna PJ, Setou M, Sobhon P.
  • Journal Title: Gen Comp Endocrinol. Volume: 223 Pages: 129-138
  • DOI: 10.1016/j.ygcen.2015.04.019
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] Collection: Expression of Human Gaucher Disease Gene GBA Generates Neurodevelopmental Defects and ER Stress in Drosophila Eye. (2015)
  • Author(s): Suzuki T, Shimoda M, Ito K, Hanai S, Aizawa H, Kato T, Kawasaki K, Yamaguchi T, Ryoo HD, Goto-Inoue N, Setou M, Tsuji S, Ishida N.
  • Journal Title: PLoS One. Volume: 10
  • DOI: 10.1371/journal.pone.0135619
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• [Journal Article] Hypoperfusion of the Adventitial Vasa Vasorum Develops an Abdominal Aortic Aneurysm. (2015)
  • Author(s): Tanaka H, Zaima N, Sasaki T, Sano M, Yamamoto N, Saito T, Inuzuka K, Hayasaka T, Goto-Inoue N, Sugiura Y, Sato K, Kugo H, Moriyama T, Konno H, Setou M, Unno N.
  • Journal Title: PLoS One. Volume: 10
  • DOI: 10.1371/journal.pone.0134386
  • Peer Reviewed / Open Access
• [Journal Article] Direct profiling of the phospholipid composition of adult Caenorhabditis elegans using whole-body imaging mass spectrometry. (2015)
  • Author(s): Hameed S, Ikegami K, Sugiyama E, Matsushita S, Kimura Y, Hayasaka T, Sugiura Y, Masaki N, Waki M, Ohta I, Hossen MA, Setou M
  • Journal Title: Anal Bioanal Chem. Volume: 407 Pages: 7589-7602
  • DOI: 10.1007/s00216-015-8932-7
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• [Journal Article] Mode of bioenergetic metabolism during B cell differentiation in the intestine determines the distinct requirement for vitamin B1 (2015)
  • Author(s): J. Kunisawa, Y. Sugiura, T. Wake, T. Nagatake, H. Suzuki, R. Nagasawa, S. Shikata, K. Honda, E. Hashimoto, Y. Suzuki, M. Setou, M. Suematsu, H. Kiyono
  • Journal Title: Cell Reports Volume: 13 Pages: 122-131
  • DOI: 10.1016/j.celrep.2015.08.063
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Ammonium sulfate improves detection of hydrophilic quaternary ammonium compounds through decreased ion suppression in matrix-assisted laser desorption/ionization imaging mass spectrometry. (2015)
  • Author(s): Sugiyama E, Masaki N, Matsushita S, Setou M.
  • Journal Title: Anal Chem. Volume: 87 Pages: 11176-11181
  • DOI: 10.1021/acs.analchem.5b02672
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Alzheimer’s disease is associated with disordered localization of ganglioside GM1 molecular species in the human dentate gyrus. (2015)
  • Author(s): Hirano-Sakamaki W, Sugiyama E, Hayasaka T, Ravid R, Setou M, Taki T.
  • Journal Title: FEBS Lett. Volume: 589 Pages: 3611-3616
  • DOI: 10.1016/j.febslet.2015.09.033
  • Peer Reviewed / Open Access
• [Journal Article] Decrease in Sphingomyelin (d18:1/16:0) in Stem Villi and Phosphatidylcholine (16:0/20:4) in Terminal Villi of Human Term Placentas with Pathohistological Maternal Malperfusion. (2015)
  • Author(s): Yamazaki K, Masaki M, Kohmura-Kobayashi Y, Chizuko Y, Hayasaka T, Itoh H, Setou M, Kanayama N.
  • Journal Title: PLoS One Volume: 10 Pages: 1-14
  • DOI: 10.1371/journal.pone.0142609
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] PGC-1α-mediated changes in phospholipid profiles of exercise-trained skeletal muscle. (2015)
  • Author(s): Senoo N, Miyoshi N, Goto-Inoue N, Minami K, Yoshimura R, Morita A, Sawada N, Matsuda J, Ogawa Y, Setou M, Kamei Y, Miura S.
  • Journal Title: J Lipid Res Volume: 56 Pages: 2286-2296
  • DOI: 10.1194/jlr.m060533
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Mechanical Stimulation by Postnasal Drip Evokes Cough. (2015)
  • Author(s): Iwata T, Ito I, Niimi A, Ikegami K, Marumo S, Tanabe N, Nakaji H, Kanemitsu Y, Matsumoto H, Kamei J, Setou M, Mishima M.
  • Journal Title: PLoS One Volume: 10
  • DOI: 10.1371/journal.pone.0141823
  • NAID: 120005749926
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 質量分析イメージング法による病理組織解析 (2015)
  • Author(s): 山崎文義、瀬藤光利
  • Journal Title: 臨床病理 Volume: 63 Pages: 472-480
• [Journal Article] 質量顕微鏡法による脂質解析 (2015)
  • Author(s): 佐藤智仁、杉山栄二、松下祥子、武井史郎、瀬藤光利
  • Journal Title: 実験医学増刊 Volume: 33 Pages: 2521-2527
• [Journal Article] 電位依存性プロトンチャネルVSOPの結晶構造から考察するプロトン漏洩制御機構 (2015)
  • Author(s): 竹下浩平、岡村康司、中川敦史
  • Journal Title: 生化学 Volume: 87(5) Pages: 625-628
  • Peer Reviewed
• [Journal Article] A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division (2015)
  • Author(s): Arasaki K, Shimizu H, Mogari H, Nishida N, Hirota N, Furuno A, Kudo Y, Baba M, Baba N, Cheng J, Fujimoto T, Ishihara N, Ortiz-Sandoval C, Barlow L, Raturi A, Dohmae N, Wakana Y, Inoue H, Tani K, Dacks J, Simmen T, Tagaya M
  • Journal Title: Dev Cell Volume: 32 Pages: 304-317
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• [Journal Article] Fatty acid-binding protein 7 regulates function of caveolae in astrocytes through expression of caveolin-1. (2015)
  • Author(s): Yoshiteru Kagawa, Yuki Yasumoto, Kazem Sharifi, Majid Ebrahimi, Ariful Islam, Hirofumi Miyazaki, Yui Yamamoto, Tomoo Sawada, Hiroko Kishi, Sei Kobayashi, Motoko Maekawa, Takeo Yoshikawa, Eiichi Takaki, Akira Nakai, Hiroshi Kogo, Toyoshi Fujimoto and Yuji Owada
  • Journal Title: GLIA Volume: 63 Pages: 780-79
  • DOI: 10.1002/glia.22784
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Hepatocyte-specific depletion of UBXD8 induces periportal steatosis in mice fed a high-fat diet (2015)
  • Author(s): Imai N, Suzuki M, Hayashi K, Ishigami M, Hirooka Y, Abe T, Shioi G, Goto H, Fujimoto T. (* co-first authors)
  • Journal Title: PLoS One Volume: 10
  • DOI: 10.1371/journal.pone.0127114
  • Peer Reviewed / Open Access
• [Journal Article] ELMOD2 is anchored to lipid droplets by palmitoylation and regulates ATGL recruitment (2015)
  • Author(s): Suzuki M, Murakami T, Cheng J, Kano H, Fukata M, Fujimoto T
  • Journal Title: Molecular biology of the cell Volume: 26 Pages: 2333-2342
  • DOI: 10.1091/mbc.e14-11-1504
  • Peer Reviewed / Open Access
• [Journal Article] Production of monoclonal antibodies against GPCR using cell-free synthesized GPCR antigen and biotinylated liposome-based interaction assay (2015)
  • Author(s): Takeda H, Ogasawara T, Ozawa T, Muraguchi A, Jih PJ, Morishita R, Uchigashima M, Watanabe M, Fujimoto T, Iwasaki T, Endo Y, Sawasaki T
  • Journal Title: Sci Rep. Volume: 5 Pages: 11333-11333
  • DOI: 10.1038/srep11333
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Deficiency in the Lipid Exporter ABCA1 Impairs Retrograde Sterol Movement and Disrupts Sterol Sensing at the Endoplasmic Reticulum (2015)
  • Author(s): Yamauchi Y, Iwamoto N, Rogers MA, Abe-Dohmae S, Fujimoto T, Chang CC, Ishigami M, Kishimoto T, Kobayashi T, Ueda K, Furukawa K, Chang TY, Yokoyama S.
  • Journal Title: J. Biol. Chem. Volume: 290 Pages: 23464-23477
  • DOI: 10.1074/jbc.m115.662668
  • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
• [Journal Article] Microscopy of membrane lipids: how precisely can we define their distribution? (2015)
  • Author(s): Takatori S and Fujimoto T
  • Journal Title: Essays in Biochemistry Volume: 57 Pages: 81-91
  • DOI: 10.1042/bse0570081
  • Peer Reviewed
• [Journal Article] Separation of Intracellular Vesicles for Immunoassays. (2015)
  • Author(s): Kobayashi T, Tanaka T, and Toyama-Sorimachi N.
  • Journal Title: Bio-protocol Volume: 5（16）
  • Peer Reviewed / Open Access
• [Journal Article] The assembly of EDC4 and Dcp1a into processing bodies is critical for the translational regulation of IL-6 (2015)
  • Author(s): Seto E, Yoshida-Sugitani R, Kobayashi T, Toyama-Sorimachi N
  • Journal Title: PloS One Volume: 10
  • DOI: 10.1371/journal.pone.0123223
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] 学研メディカル秀潤社 (2015)
  • Author(s): 小林俊彦、反町典子
  • Journal Title: 細胞工学6月号 Volume: 34 Pages: 557-561
• [Journal Article] 羊土社 (2015)
  • Author(s): 小林俊彦、反町典子
  • Journal Title: 実験医学増刊号 Volume: 33 Pages: 75-82
• [Journal Article] The absence of the leukotriene B4 receptor BLT1 attenuates peripheral inflammation and spinal nociceptive processing following intraplantar formalin injury (2015)
  • Author(s): Asahara M, Ito N, Yokomizo T, Nakamura M, Shimizu T, Yamada Y.
  • Journal Title: Mol Pain. Volume: 11 Pages: 11-11
  • DOI: 10.1186/s12990-015-0010-9
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The leukotriene B4 receptor BLT1 is stabilized by transmembrane helix capping mutations. (2015)
  • Author(s): Hori, T., Nakamura, M., Yokomizo, T., Shimizu, T., Miyano, M.
  • Journal Title: Biochem. Biophys. Volume: 4 Pages: 243-249
  • DOI: 10.1016/j.bbrep.2015.09.007
  • Peer Reviewed / Open Access
• [Journal Article] Biochemical characterization of three BLT receptors in zebrafish. (2015)
  • Author(s): Okuno T, Ishitani T, Yokomizo T.
  • Journal Title: PLoS One Volume: 10 Pages: 0117888-0117888
  • DOI: 10.1371/journal.pone.0117888
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration (2015)
  • Author(s): Zandi S, Nakao S, Chun K H, Fiorina P, Sun D, Arita R, Zhao M, Kim E, Schueller O, Campbell S, Taher M, Melhorn M I, Schering A, Gatti F, Tezza S, Xie F, Vergani A, Yoshida S, Ishikawa K, Yamaguchi M, Sasaki F, Schmidt-Ullrich R, Hata Y, Enaida H, Yuzawa M, Yokomizo T, 4名
  • Journal Title: Cell Rep. Volume: 10 Pages: 1173-1186
  • DOI: 10.1016/j.celrep.2015.01.050
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Two distinct leukotriene B4 receptors, BLT1 and BLT2 (2015)
  • Author(s): Yokomizo T.
  • Journal Title: J Biochem Volume: 157 Pages: 65-71
  • DOI: 10.1093/jb/mvu078
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] The role of leukotrienes in allergic diseases (2015)
  • Author(s): Liu M, Yokomizo T.
  • Journal Title: Allergol. Int. Volume: 64 Issue: 1 Pages: 17-26
  • DOI: 10.1016/j.alit.2014.09.001
  • NAID: 130004873117
  • ISSN: 1323-8930, 1440-1592
  • Peer Reviewed / Open Access
• [Journal Article] 12-HHT 皮膚創傷治癒に働く新しいCOX代謝物. (2015)
  • Author(s): 佐伯和子, 劉珉, 横溝岳彦.
  • Journal Title: 医学のあゆみ Volume: 254 Pages: 1121-1125
• [Journal Article] 血小板由来の脂質メディエーター12-HHTは角化細胞の移動を亢進させ皮膚創傷治癒を促進する. (2015)
  • Author(s): 佐伯和子, 劉珉, 横溝岳彦.
  • Journal Title: 血栓止血 Volume: 26 Pages: 611-618
  • NAID: 130005113961
• [Journal Article] 脂質メディエーターによる免疫・炎症応答の制御 (2015)
  • Author(s): 李賢哲, 奥野利明, 横溝岳彦.
  • Journal Title: 臨床免疫・アレルギー科 Volume: 64 Pages: 386-390
  • NAID: 40020622928
• [Journal Article] 第1世代脂質メディエーター エイコサノイド (2015)
  • Author(s): 横溝岳彦
  • Journal Title: 実験医学 Volume: 33 Pages: 2344-2348
• [Journal Article] 【アセトアミノフェン】 薬理学的側面から 古くて新しい謎だらけの薬 (2015)
  • Author(s): 横溝岳彦
  • Journal Title: LiSA Volume: 22 Pages: 874-877
• [Journal Article] Roles of prostaglandin receptors in female reproduction. (2015)
  • Author(s): Sugimoto Y, Inazumi T, Tsuchiya S
  • Journal Title: The Journal of Biochemistry Volume: 157 Pages: 73-80
  • DOI: 10.1093/jb/mvu081
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Prostaglandin E2-induced inflammation: relevance of prostaglandin E receptors. (2015)
  • Author(s): Kawahara K, Hohjoh H, Inazumi T, Tsuchiya S, Sugimoto Y
  • Journal Title: Biochimica et Biophysica Acta Volume: 1851 Pages: 414-421
  • DOI: 10.1016/j.bbalip.2014.07.008
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Dermal Vγ4(+) γδ T Cells Possess a Migratory Potency to the Draining Lymph Nodes and Modulate CD8(+) T-Cell Activity through TNF-α Production. (2015)
  • Author(s): Nakamizo S, Egawa G, Tomura M, Sakai S, Tsuchiya S, Kitoh A, Honda T, Otsuka A, Nakajima S, Dainichi T, Tanizaki H, Mitsuyama M, Sugimoto Y, Kawai K, Yoshikai Y, Miyachi Y, Kabashima K.
  • Journal Title: J. Invest. Dermatol. Volume: 135 Issue: 4 Pages: 1007-1015
  • DOI: 10.1038/jid.2014.516
  • NAID: 120005621945
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] p13 overexpression in pancreatic b-cells ameliorates type 2 diabetes in high-fat-fed mice (2015)
  • Author(s): Higashi, S. et al.
  • Journal Title: Biochem Biophys Res Commun. Volume: 461 Pages: 612-617
  • DOI: 10.1016/j.bbrc.2015.04.074
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Comparative gene expression profiles in pancreatic islets associated with agouti yellow mutation and PACAP overexpression in mice (2015)
  • Author(s): Ikeda K, Tomimoto S, Tsuchiya S, Hamagami K, Shintani N, Sugimoto Y, Ichikawa A, Kasai A, Nakazawa T, Nagayasu K, Hayata-Takano A, Baba A, Hashimoto H
  • Journal Title: Biochemistry and Biophysics Reports Volume: 2 Pages: 179-183
  • DOI: 10.1016/j.bbrep.2015.06.006
  • Peer Reviewed / Open Access
• [Journal Article] Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling that Drives Tumor Growth, Angiogenesis and Metastasis. (2015)
  • Author(s): Inada M, Takita M, Yokoyama S, Watanabe K, Tominari T, Matsumoto C, Hirata M, Maru Y, Maruyama T, Sugimoto Y, Narumiya S, Uematsu S, Akira S, Murphy G, Nagase H, Miyaura C.
  • Journal Title: J Biol Chem Volume: 290 Pages: 29781-29793
  • DOI: 10.1074/jbc.m115.669481
  • Peer Reviewed / Open Access / Int'l Joint Research
• [Journal Article] プロスタグランジンによる皮膚マスト細胞の成熟と活性化 (2015)
  • Author(s): 杉本幸彦
  • Journal Title: 臨床免疫・アレルギー科 Volume: 63 Pages: 62-67
  • NAID: 40020330437
• [Journal Article] プロスタグランジンによる神経機能の調節機構 (2015)
  • Author(s): 杉本幸彦
  • Journal Title: 日薬理誌 Volume: 145 Pages: 237-242
  • NAID: 130005067370
• [Journal Article] 炎症反応におけるプロスタグランジンE2の役割 (2015)
  • Author(s): 岩崎亮, 北條寛典, 杉本幸彦
  • Journal Title: 細胞 Volume: 47 Pages: 266-269
• [Journal Article] プロスタグランジンによる女性生殖制御の意義 (2015)
  • Author(s): 告恭史郎, 杉本幸彦
  • Journal Title: 実験医学 Volume: 33（15） Pages: 164-169
• [Journal Article] 急性炎症にかかわるプロスタグランジンとその働き (2015)
  • Author(s): 杉本幸彦
  • Journal Title: 医学のあゆみ Volume: 254（12） Pages: 1091-1096
• [Journal Article] Blood levels of serotonin are specifically correlated with plasma lysophosphatidylserine among the glycero-lysophospholipids (2015)
  • Author(s): Kurano M, Dohi T, Nojiri T, Kobayashi T, Hirowatari Y, Inoue A, Kano K, Matsumoto H, Igarashi K, Nishikawa M, Miyauchi K, Daida H, Ikeda H, Aoki J, Yatomi Y
  • Journal Title: BBA Clin Volume: 4 Pages: 92-8
  • DOI: 10.1016/j.bbacli.2015.08.003
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] A New Enzyme Immunoassay for the Quantitative Determination of Classical Autotaxins (ATXα, ATXβ, and ATXγ) and Novel Autotaxins (ATXδ and ATXε) (2015)
  • Author(s): Tokuhara Y, Kurano M, Shimamoto S, Igarashi K, Nojiri T, Kobayashi T, Masuda A, Ikeda H, Nagamatsu T, Fujii T, Aoki J, Yatomi Y
  • Journal Title: PLoS One Volume: 10
  • DOI: 10.1371/journal.pone.0130074
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Possible involvement of sphingomyelin in the regulation of the plasma sphingosine 1-phosphate level in human subjects (2015)
  • Author(s): Ohkawa R, Kurano M, Mishima Y, Nojiri T, Tokuhara Y, Kishimoto T, Nakamura K, Okubo S, Hosogaya S, Ozaki Y, Yokota H, Igarashi K, Ikeda H, Tozuka M, Yatomi Y
  • Journal Title: Clin Biochem Volume: 48 Pages: 690-697
  • DOI: 10.1016/j.clinbiochem.2015.03.019
  • Peer Reviewed / Acknowledgement Compliant
• [Journal Article] Lysophosphatidylserine has Bilateral Effects on Macrophages in the Pathogenesis of Atherosclerosis (2015)
  • Author(s): Nishikawa M, Kurano M, Ikeda H, Aoki J, Yatomi Y
  • Journal Title: J Atheroscler Thromb Volume: 22 Issue: 5 Pages: 518-26
  • DOI: 10.5551/jat.25650
  • NAID: 130004704381
  • ISSN: 1340-3478, 1880-3873
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Possible involvement of minor lysophospholipids in the increase in plasma lysophosphatidic acid in acute coronary syndrome. (2015)
  • Author(s): Kurano M, Suzuki A, Inoue A, Tokuhara Y, Kano K, Matsumoto H, Igarashi K, Ohkawa R, Nakamura K, Dohi T, Miyauchi K, Daida H, Tsukamoto K, Ikeda H, Aoki J, Yatomi Y
  • Journal Title: Arterioscler. Thromb. Vasc. Biol. Volume: 35 Pages: 463-470
  • DOI: 10.1161/atvbaha.114.304748
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] LDL Receptor and ApoE are Involved in the Clearance of ApoM-associated Sphingosine 1-phosphate (2015)
  • Author(s): Kurano M, Tsukamoto K, Hara M, Ohkawa R, Ikeda H, Yatomi Y.
  • Journal Title: J Biol Chem Volume: 290 Pages: 2477-88
  • DOI: 10.1074/jbc.m114.596445
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] リゾリン脂質を標的とした診断と創薬 (2015)
  • Author(s): 蔵野 信，可野 邦行，矢冨 裕，青木 淳賢