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Toward an integrative understanding of functional zones in organelles

Administrative Group

Project AreaToward an integrative understanding of functional zones in organelles
Project/Area Number 17H06413
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionTokyo Medical and Dental University

Principal Investigator

清水 重臣  東京医科歯科大学, 難治疾患研究所, 教授 (70271020)

Co-Investigator(Kenkyū-buntansha) 花田 賢太郎  国立感染症研究所, 品質保証・管理部, 主任研究官 (30192701)
新井 洋由  東京大学, 大学院医学系研究科(医学部), 客員研究員 (40167987)
原田 彰宏  大阪大学, 医学系研究科, 教授 (40251441)
黒川 量雄  国立研究開発法人理化学研究所, 光量子工学研究センター, 専任研究員 (40333504)
後藤 聡  立教大学, 理学部, 教授 (60280575)
齊藤 達哉  大阪大学, 薬学研究科, 教授 (60456936)
森 和俊  京都大学, 理学研究科, 教授 (70182194)
加藤 薫  国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 (80356782)
中野 明彦  国立研究開発法人理化学研究所, 光量子工学研究センター, 副センター長 (90142140)
今泉 和則  広島大学, 医系科学研究科(医), 教授 (90332767)
Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Granted (Fiscal Year 2021)
Budget Amount *help
¥120,640,000 (Direct Cost: ¥92,800,000、Indirect Cost: ¥27,840,000)
Fiscal Year 2021: ¥21,840,000 (Direct Cost: ¥16,800,000、Indirect Cost: ¥5,040,000)
Fiscal Year 2020: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2019: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2018: ¥24,310,000 (Direct Cost: ¥18,700,000、Indirect Cost: ¥5,610,000)
Fiscal Year 2017: ¥25,870,000 (Direct Cost: ¥19,900,000、Indirect Cost: ¥5,970,000)
Keywords細胞生物 / オルガネラ / ミトコンドリア / 小胞体 / ゴルジ体 / ゾーン / エンドソーム / 超解像顕微鏡
Outline of Annual Research Achievements

オルガネラ・ゾーン研究を、領域全体で有機的に進めることができるように、様々な施策を行った。特に、公募班に対する支援体制の整備、情報の相互交換、共同研究の推進を図った。新型コロナ感染症が発生したために、対面式での会議を開催することは困難となったが、代替としてon lineでの会議を行った。具体的には、全体班会議を2回開催し、研究の進捗状況を班員全員で共有する場を、例年通りに設けた。また、班全体の運営を議論する総括班会議を2回開催し、コロナ禍の中でも滞りなく研究を進捗する体制を構築した。また、本領域では、若手研究者のプロモーションにも力を入れており、「第3回若手の会」も、同様にon lineで開催した。国際的な活動は大きく制限され、研究者派遣や研究者招聘はできなかったが、on line会議において、keynote talk/invited talkを、延べ11回行った。
技術支援部門では、イメージングやプロテオミクス、電子顕微鏡解析などの技術を、計画班、公募班に提供し、約19件の技術支援が行われた。また、62件の共同研究が為された(総括班員同士が48件、総括班と公募班で10件、公募班同士で4件)。さらに、ホームページやニュースレターを通して、領域の進捗を広く公開したほか、アウトリーチを29件、プレスリリースを27件行った。これらの成果として、国際論文に関しては、計画班126報、公募班57報の論文を公表し、教員のプロモーションは6名(うち、教授2名、准教授2名)の成果を上げた。

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

コロナ禍の中でも、当初予定していた、総括班会議、「全体班会議」などの開催を順調に行った。また、多くの共同研究を実施することができた。重要なことに、これらの研究を進める間に、領域内のメンバー間の信頼が深まり、領域一体となって研究を行う意識が涵養された。さらに、SCLIM顕微鏡、超解像顕微鏡、電子顕微鏡、糖鎖解析、リピドミクス、プロテオミクス、siRNAスクリーニングライブラリー、ケミカルバイオロジーなど、お互いの技術を班内で共有する技術支援も非常に有効に機能した。実際に、これらを活用した共同研究も多く進行している。若手育成に関しても、「オルガネラゾーン若手の会」を予定通り行なった。「オルガネラ・ゾーン統合解析プロジェクト」の研究も進みつつあるほか、領域内共同研究も進行している。以上のことから、総括班の活動は極めて順調に遂行されていると判断される。

Strategy for Future Research Activity

引き続き、コロナ禍の中でも、現在の管理体制、技術支援体制を継続して行う。また、コロナ禍を積極的に利用して、on lineを通じて頻回に議論する体制を構築する。班会議は、半年おきに、全体会議とプログレスレポートを開催し、お互いの研究成果や研究手法の共有、研究者間の情報交換、研究材料の相互活用などを行う。また本年も、若手育成に重点をおいた、若手のみからなる研究会を企画している。研究支援面では、さらに技術支援を相互利用するよう勧奨する。ホームページでは、引き続きオルガネラゾーンに関する情報を提供する。また、「オルガネラ・ゾーン統合解析プロジェクト」を遂行する。

Report

(4 results)
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report

Research Products

(157 results)

All 2021 2020 2019 2018 2017 Other

All Int'l Joint Research (10 results) Journal Article (92 results) (of which Int'l Joint Research: 32 results,  Peer Reviewed: 92 results,  Open Access: 71 results,  Acknowledgement Compliant: 1 results) Presentation (48 results) (of which Int'l Joint Research: 44 results,  Invited: 26 results) Book (1 results) Remarks (3 results) Patent(Industrial Property Rights) (2 results) (of which Overseas: 1 results) Funded Workshop (1 results)

  • [Int'l Joint Research] ペンシルベニヤ州立大学(米国)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] バルセロナ大学(スペイン)

    • Related Report
      2020 Annual Research Report
  • [Int'l Joint Research] Penn state University(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Yonsei university(韓国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] Kings colledge of London/Cancer Research UK(英国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Monash University/Walter and Eliza Hall Institute(Australia)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Universidad de Sevilla(Spain)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Harvard University/Icahn School of Medicine at Mount Sinai/NIH(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Yonsei University College of Medicine(韓国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2017 Annual Research Report
  • [Journal Article] SNAP23 deficiency causes severe brain dysplasia through the loss of radial glial cell polarity2021

    • Author(s)
      Kunii M、Noguchi Y、Yoshimura S、Kanda S、Iwano T、Avriyanti E、Atik N、Sato T、Sato K、Ogawa M、Harada A
    • Journal Title

      The Journal of cell biology

      Volume: 220 Pages: 1-21

    • DOI

      10.1083/jcb.201910080

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ER-resident sensor PERK is essential for mitochondrial thermogenesis in brown adipose tissue.2020

    • Author(s)
      Kato H, Okabe K, Miyake M, Hattori K, Fukaya T, Tanimoto K, Beini S, Mizuguchi M, Torii S, Arakawa S, Ono M, Saito Y, Sugiyama T, Funatsu T, Sato K, Shimizu S, Oyadomari S, Ichijo H, Kadowaki H, Nishitoh H.
    • Journal Title

      Life Science Alliance

      Volume: 3 Pages: 201900576-201900576

    • DOI

      10.26508/lsa.201900576

    • NAID

      120006980545

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Identification of a phosphorylation site on Ulk1 required for genotoxic stress-induced alternative autophagy2020

    • Author(s)
      Torii Satoru、Yamaguchi Hirofumi、Nakanishi Akira、Arakawa Satoko、Honda Shinya、Moriwaki Kenta、Nakano Hiroyasu、Shimizu Shigeomi
    • Journal Title

      Nature Communications

      Volume: 11 Pages: 1754-1754

    • DOI

      10.1038/s41467-020-15577-2

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages2020

    • Author(s)
      Yasueda Asuka、Kayama Hisako、Murohashi Michiko、Nishimura Junichi、Wakame Koji、Komatsu Ken-ichi、Ogino Takayuki、Miyoshi Norikatsu、Takahashi Hidekazu、Uemura Mamoru、Matsuda Chu、Kitagawa Toru、Takeda Kiyoshi、Ito Toshinori、Doki Yuichiro、Eguchi Hidetoshi、Shimizu Shigeomi、Mizushima Tsunekazu
    • Journal Title

      Scientific Reports

      Volume: 10

    • DOI

      10.1038/s41598-020-65306-4

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Wipi3 is essential for alternative autophagy and its loss causes neurodegeneration2020

    • Author(s)
      Yamaguchi Hirofumi、Honda Shinya、Torii Satoru、Shimizu Kimiko、Katoh Kaoru、Miyake Koichi、Miyake Noriko、Fujikake Nobuhiro、Sakurai Hajime Tajima、Arakawa Satoko、Shimizu Shigeomi
    • Journal Title

      Nature Communications

      Volume: 11 Pages: 5311-5311

    • DOI

      10.1038/s41467-020-18892-w

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Palmitoylated CKAP4 regulates mitochondrial functions through an interaction with VDAC2 at ER&[minus]mitochondria contact sites.2020

    • Author(s)
      Harada, T., Sada, R., Osugi, Y., Matsumoto, S., Matsuda, T., Hayashi-Nishino, M., Nagai, T., Harada, A., Kikuchi, A.
    • Journal Title

      J Cell Sci.

      Volume: 133 Issue: 21

    • DOI

      10.1242/jcs.249045

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] MYB-like transcription factor NoPSR1 is crucial for membrane lipid remodelingunder phosphate starvation in the oleaginous microalga Nannochloropsis oceanica2020

    • Author(s)
      Murakami H, Kakutani N, Kuroyanagi Y, Iwai M, Hori K, Shimojima M, Ohta H
    • Journal Title

      FEBS Letters

      Volume: 594 Pages: 3384-3384

    • DOI

      10.1002/1873-3468.13902

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Lamin is essential for nuclear localization of the GPI synthesis enzyme PIG-B and GPI-anchored protein production in Drosophila2020

    • Author(s)
      Yamamoto-Hino Miki、Kawaguchi Kohei、Ono Masaya、Furukawa Kazuhiro、Goto Satoshi
    • Journal Title

      Journal of Cell Science

      Volume: 133 Pages: 238527-238527

    • DOI

      10.1242/jcs.238527

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Blood group P1 antigen?bearing glycoproteins are functional but less efficient receptors of Shiga toxin than conventional glycolipid-based receptors2020

    • Author(s)
      Morimoto K, Suzuki N, Tanida I, Kakuta S, Furuta Y, Uchiyama Y, Hanada K, Suzuki Y, Yamaji T.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Pages: 9490-9501

    • DOI

      10.1074/jbc.ra120.013926

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Protrudin and PDZD8 contribute to neuronal integrity by promoting lipid extraction required for endosome maturation2020

    • Author(s)
      Shirane Michiko、Wada Mariko、Morita Keiko、Hayashi Nahoki、Kunimatsu Reina、Matsumoto Yuki、Matsuzaki Fumiko、Nakatsumi Hirokazu、Ohta Keisuke、Tamura Yasushi、Nakayama Keiichi I.
    • Journal Title

      Nat. Commun.

      Volume: 11 Pages: 4576-4576

    • DOI

      10.1038/s41467-020-18413-9

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Organelle membrane-specific chemical labeling and dynamic imaging in living cells.2020

    • Author(s)
      Tomonori Tamura, Alma Fujisawa, Masaki Tsuchiya, Yuying Shen, Kohjiro Nagao, Shin Kawano, Yasushi Tamura, Toshiya Endo, Masato Umeda, Itaru Hamachi
    • Journal Title

      Nat. Chem. Biol.

      Volume: 16 Pages: 1361-1367

    • DOI

      10.1038/s41589-020-00651-z

    • NAID

      120006898122

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Antipsychotic olanzapine-induced misfolding of proinsulin in the endoplasmic reticulum accounts for atypical development of diabetes2020

    • Author(s)
      Ninagawa Satoshi、Tada Seiichiro、Okumura Masaki、Inoguchi Kenta、Kinoshita Misaki、Kanemura Shingo、Imami Koshi、Umezawa Hajime、Ishikawa Tokiro、Mackin Robert B、Torii Seiji、Ishihama Yasushi、Inaba Kenji、Anazawa Takayuki、Nagamine Takahiko、Mori Kazutoshi
    • Journal Title

      eLife

      Volume: 9 Pages: 23-31

    • DOI

      10.7554/elife.60970

    • NAID

      120006898101

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome2020

    • Author(s)
      Deng Zimu、Chong Zhenlu、Law Christopher S.、Mukai Kojiro、Ho Frances O.、Martinu Tereza、Backes Bradley J.、Eckalbar Walter L.、Taguchi Tomohiko、Shum Anthony K.
    • Journal Title

      Journal of Experimental Medicine

      Volume: 217 Pages: 2128-2135

    • DOI

      10.1084/jem.20201045

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Tricalbins are required for nonvesicular ceramide transport at ER-Golgi contacts and modulate lipid droplet biogenesis.2020

    • Author(s)
      Atsuko Ikeda, Philipp Schlarmann, Kazuo Kurokawa, Akihiko Nakano, Howard Riezman, and Kouichi Funato.
    • Journal Title

      iScience

      Volume: 23 Pages: 101603-101603

    • DOI

      10.1016/j.isci.2020.101603

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Ceramide chain length-dependent protein sorting into selective endoplasmic reticulum exit sites.2020

    • Author(s)
      Sofia Rodriguez-Gallardo, Kazuo Kurokawa, Susana Sabido-Bozo, Alejandro Cortes-Gomez, Atsuko Ikeda, Valeria Zoni, Auxiliadora Aguilera-Romero, Ana Maria Perez-Linero, Sergio Lopez, Miho Waga, Misako Araki, Miyako Nakano, Howard Riezman, Kouichi Funato, Stefano Vanni, Akihiko Nakano, Manuel Muñiz.
    • Journal Title

      Sci Adv.

      Volume: 6

    • DOI

      10.1126/sciadv.aba8237

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The liverwort oil body is formed by redirection of the secretory pathway2020

    • Author(s)
      Kanazawa T., Morinaka H., Ebine K., Shimada T.L., Ishida S., Minamino N., Yamaguchi K., Shigenobu S., Kohchi T., Nakano A., Ueda T.
    • Journal Title

      Nature Communications

      Volume: 11 Pages: 6152-6152

    • DOI

      10.1038/s41467-020-19978-1

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Role of Tissue-Specific Ubiquitin Ligases, RNF183, RNF186, RNF182 and RNF152, in Disease and Biological Function2020

    • Author(s)
      Okamoto Takumi、Imaizumi Kazunori、Kaneko Masayuki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 3921-3921

    • DOI

      10.3390/ijms21113921

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Bi-allelic Variants in the GPI Transamidase Subunit PIGK Cause a Neurodevelopmental Syndrome with Hypotonia, Cerebellar Atrophy, and Epilepsy2020

    • Author(s)
      Nguyen Thi Tuyet Mai、Murakami Yoshiko、Mobilio Sabrina、Rosenfeld Jill A.、St-Denis Anik、Elrick Matthew J.、Anselm Irina、Rodan Lance H.、Tartaglia Marco、Gleeson Joseph、Kinoshita Taroh、Campeau Philippe M.
    • Journal Title

      Am. J. Hum. Genet

      Volume: 106 Pages: 484-495

    • DOI

      10.1016/j.ajhg.2020.03.001

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] α2,3 linkage of sialic acid to a GPI anchor and an unpredicted GPI attachment site in human prion protein2020

    • Author(s)
      Kobayashi Atsushi、Hirata Tetsuya、Nishikaze Takashi、Ninomiya Akinori、Maki Yuta、Takada Yoko、Kitamoto Tetsuyuki、Kinoshita Taroh
    • Journal Title

      J. Biol. Chem

      Volume: 295 Pages: 7789-7798

    • DOI

      10.1074/jbc.ra120.013444

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Recycling endosomes attach to the trans-side of Golgi stacks in Drosophila and mammalian cells2020

    • Author(s)
      Fujii Syara、Kurokawa Kazuo、Inaba Ryota、Hiramatsu Naoki、Tago Tatsuya、Nakamura Yuri、Nakano Akihiko、Satoh Takunori、Satoh Akiko K.
    • Journal Title

      Journal of Cell Science

      Volume: 133 Pages: 236935-236935

    • DOI

      10.1242/jcs.236935

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impaired actin dynamics and suppression of Shank2-mediated spine enlargement in cortactin knockout mice2020

    • Author(s)
      Tanaka Shinji、Masuda Yasutaka、Harada Akihiro、Okabe Shigeo
    • Journal Title

      Microscopy

      Volume: 69 Pages: 44-52

    • DOI

      10.1093/jmicro/dfaa001

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit2020

    • Author(s)
      Okamoto Takumi、Wu Yan、Matsuhisa Koji、Saito Atsushi、Sakaue Fumika、Imaizumi Kazunori、Kaneko Masayuki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 521 Pages: 1030-1035

    • DOI

      10.1016/j.bbrc.2019.11.001

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Production of BBF2H7‐derived small peptide fragments via endoplasmic reticulum stress‐dependent regulated intramembrane proteolysis2020

    • Author(s)
      Matsuhisa Koji、Saito Atsushi、Cai Longjie、Kaneko Masayuki、Okamoto Takumi、Sakaue Fumika、Asada Rie、Urano Fumihiko、Yanagida Kanta、Okochi Masayasu、Kudo Yukitsuka、Matsumoto Masaki、Nakayama Keiichi I.、Imaizumi Kazunori
    • Journal Title

      The FASEB Journal

      Volume: 34 Pages: 865-880

    • DOI

      10.1096/fj.201901748r

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] EDEM2 stably disulfide-bonded to TXNDC11 catalyzes the first mannose trimming step in mammalian glycoprotein ERAD2020

    • Author(s)
      George Ginto、Ninagawa Satoshi、Yagi Hirokazu、Saito Taiki、Ishikawa Tokiro、Sakuma Tetsushi、Yamamoto Takashi、Imami Koshi、Ishihama Yasushi、Kato Koichi、Okada Tetsuya、Mori Kazutoshi
    • Journal Title

      eLife

      Volume: 9

    • DOI

      10.7554/elife.53455

    • NAID

      120006817590

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Development of a Rapid <i>in vivo</i> Assay to Evaluate the Efficacy of IRE1-specific Inhibitors of the Unfolded Protein Response Using Medaka Fish2020

    • Author(s)
      Jin Byungseok、Ishikawa Tokiro、Taniguchi Mai、Ninagawa Satoshi、Okada Tetsuya、Kagaya Shigehide、Mori Kazutoshi
    • Journal Title

      Cell Struct. Funct.

      Volume: 45 Issue: 1 Pages: 23-31

    • DOI

      10.1247/csf.19032

    • NAID

      130007795672

    • ISSN
      0386-7196, 1347-3700
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF62020

    • Author(s)
      Koba Hibiki、Jin Shengyu、Imada Nanami、Ishikawa Tokiro、Ninagawa Satoshi、Okada Tetsuya、Sakuma Tetsushi、Yamamoto Takashi、Mori Kazutoshi
    • Journal Title

      Cell Struct. Funct.

      Volume: 45 Issue: 1 Pages: 9-21

    • DOI

      10.1247/csf.19030

    • NAID

      130007792116

    • ISSN
      0386-7196, 1347-3700
    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Chlamydia trachomatis‐infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 22020

    • Author(s)
      Tachida Yuriko、Kumagai Keigo、Sakai Shota、Ando Shuji、Yamaji Toshiyuki、Hanada Kentaro
    • Journal Title

      FEBS Letters

      Volume: 594 Pages: 519-529

    • DOI

      10.1002/1873-3468.13632

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organelle contacts: Sub‐organelle zones to facilitate rapid and accurate inter‐organelle trafficking of lipids2020

    • Author(s)
      Hanada Kentaro
    • Journal Title

      Traffic (Copenhagen, Denmark)

      Volume: 21 Pages: 189-196

    • DOI

      10.1111/tra.12716

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Three‐Component, One‐Pot Tandem Sonogashira/Suzuki‐Miyaura Coupling Reactions for the Synthesis of a Library of Ceramide‐Transport Protein Inhibitors Designed In Silico2020

    • Author(s)
      Ueno Masaharu、Miyoshi Norikazu、Hanada Kentaro、Kobayashi Shu
    • Journal Title

      Asia Journal of Organic Chemistry

      Volume: 9 Pages: 267-273

    • DOI

      10.1002/ajoc.201900689

    • NAID

      120007001416

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] The Ceramide Analogue N-(1-hydroxy-3-morpholino-1-phenylpropan-2-yl)decanamide Induces Large Lipid Droplet Accumulation and Highlights the Effect of LAMP-2 Deficiency on Lipid Droplet Degradation2020

    • Author(s)
      Yuji Kato, Satoko Arakawa, Kazue Terasawa, Jin-Ichi Inokuchi, Takanori Iwata, Shigeomi Shimizu, Tetsuro Watabe, Miki Hara-Yokoyama
    • Journal Title

      Bioorganic & Medicinal Chemistry Letters

      Volume: 30 Pages: 126891-126891

    • DOI

      10.1016/j.bmcl.2019.126891

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Sanguisorba officinalis L. derived from herbal medicine prevents intestinal inflammation by inducing autophagy in macrophages.2020

    • Author(s)
      Yasueda A, Kayama H, Murohashi M, Nishimura J, Wakame K, Komatsu K, Ogino T, Miyoshi N, Takahashi H, Uemura M, Matsuda C, Kitagawa T, Takeda K, Ito T, Doki Y, Eguchi H, Shimizu S, Mizushima T
    • Journal Title

      Scientific Reports

      Volume: press

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Role of Atg8 in the regulation of vacuolar membrane invagination2019

    • Author(s)
      Ishii Ayane、Kurokawa Kazuo、Hotta Miyuu、Yoshizaki Suzuka、Kurita Maki、Koyama Aya、Nakano Akihiko、Kimura Yoko
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 14828-14828

    • DOI

      10.1038/s41598-019-51254-1

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Spatiotemporal dissection of the trans-Golgi network in budding yeast2019

    • Author(s)
      Takuro Tojima, Yasuyuki Suda, Midori Ishii, Kazuo Kurokawa, Akihiko Nakano
    • Journal Title

      Journal of Cell Science

      Volume: 132 Pages: 231159-231159

    • DOI

      10.1242/jcs.231159

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] COPII proteins exhibit distinct subdomains within each ER exit site for executing their functions2019

    • Author(s)
      Maeda Miharu、Kurokawa Kazuo、Katada Toshiaki、Nakano Akihiko、Saito Kota
    • Journal Title

      Sci Rep.

      Volume: 9 Pages: 7346-7346

    • DOI

      10.1038/s41598-019-43813-3

    • NAID

      120007169371

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Visualization of secretory cargo transport within the Golgi apparatus2019

    • Author(s)
      Kurokawa K, Osakada H, Kojidani T, Waga M, Suda Y, Asakawa H, Haraguchi T, Nakano A.
    • Journal Title

      Journal of Cell Biology

      Volume: - Pages: 1602-1618

    • DOI

      10.1083/jcb.201807194

    • NAID

      120007133506

    • Related Report
      2019 Annual Research Report 2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Editorial overview: Membrane Trafficking2019

    • Author(s)
      Peter J. Cullen、Akihiko Nakano
    • Journal Title

      Current Opinion in Cell Biology

      Volume: 59 Pages: 1-166

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Organelle zones2019

    • Author(s)
      Nakano Akihiko、von Blume Julia
    • Journal Title

      Molecular Biology of the Cell

      Volume: 30 Pages: 731-731

    • DOI

      10.1091/mbc.e18-12-0818

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Roles of collagen XXV and its putative receptors PTP s/d in intramuscular motor innervation and congenital cranial dysinnervation disorder2019

    • Author(s)
      Haruka Munezane, Hiroaki Oizumi, Tomoko Wakabayashi, Shu Nishio, Tomoko Hirasawa, Takashi Sato, Akihiro Harada, Tomoyuki Yoshida, Takahiro Eguchi, Yuji Yamanashi, Tadafumi Hashimoto, Takeshi Iwatsubo
    • Journal Title

      Cell Reports

      Volume: 29 Pages: 4362-4376

    • DOI

      10.1016/j.celrep.2019.11.112

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation2019

    • Author(s)
      Wu Yan、Kimura Yuka、Okamoto Takumi、Matsuhisa Koji、Asada Rie、Saito Atsushi、Sakaue Fumika、Imaizumi Kazunori、Kaneko Masayuki
    • Journal Title

      Scientific Reports

      Volume: 9 Pages: 20301-20301

    • DOI

      10.1038/s41598-019-56748-6

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Renal medullary tonicity regulates RNF183 expression in the collecting ducts via NFAT52019

    • Author(s)
      Maeoka Yujiro、Okamoto Takumi、Wu Yan、Saito Atsushi、Asada Rie、Matsuhisa Koji、Terao Miho、Takada Shuji、Masaki Takao、Imaizumi Kazunori、Kaneko Masayuki
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 514 Pages: 436-442

    • DOI

      10.1016/j.bbrc.2019.04.168

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Calnexin promotes the folding of mutant iduronate 2-sulfatase related to mucopolysaccharidosis type II2019

    • Author(s)
      Osaki Yosuke、Matsuhisa Koji、Che Wang、Kaneko Masayuki、Asada Rie、Masaki Takao、Imaizumi Kazunori、Saito Atsushi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 514 Pages: 217-223

    • DOI

      10.1016/j.bbrc.2019.04.115

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Cartilage endoplasmic reticulum stress may influence the onset but not the progression of experimental osteoarthritis2019

    • Author(s)
      Kung Louise H. W.、Mullan Lorna、Soul Jamie、Wang Ping、Mori Kazutoshi、Bateman John F.、Briggs Michael D.、Boot-Handford Raymond P.
    • Journal Title

      Arthritis Res. Ther.

      Volume: 21 Pages: 206-206

    • DOI

      10.1186/s13075-019-1988-6

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Structure, functions and regulation of CERT, a lipid‐transfer protein for the delivery of ceramide at the ER?Golgi membrane contact sites2019

    • Author(s)
      Kumagai Keigo、Hanada Kentaro
    • Journal Title

      FEBS Letters

      Volume: 593 Pages: 2366-2377

    • DOI

      10.1002/1873-3468.13511

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characterization of monoclonal antibodies recognizing each extracellular loop domain of occludin2019

    • Author(s)
      Shimizu Yoshimi、Shirasago Yoshitaka、Suzuki Takeru、Hata Tomoyuki、Kondoh Masuo、Hanada Kentaro、Yagi Kiyohito、Fukasawa Masayoshi
    • Journal Title

      Journal of Biochemistry

      Volume: 166 Pages: 297-308

    • DOI

      10.1093/jb/mvz037

    • NAID

      40022023629

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-Regulating Factor2019

    • Author(s)
      Yamaji Toshiyuki、Hanamatsu Hisatoshi、Sekizuka Tsuyoshi、Kuroda Makoto、Iwasaki Norimasa、Ohnishi Makoto、Furukawa Jun-ichi、Yahiro Kinnosuke、Hanada Kentaro
    • Journal Title

      iScience

      Volume: 15 Pages: 407-420

    • DOI

      10.1016/j.isci.2019.05.005

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Autophagy Regulation of Metabolism Is Required for CD8+ T Cell Anti-tumor Immunity2019

    • Author(s)
      DeVorkin Lindsay、Pavey Nils、Carleton Gillian、Comber Alexandra、Ho Cally、Lim Junghyun、McNamara Erin、Huang Haochu、Kim Paul、Zacharias Lauren G.、Mizushima Noboru、Saitoh Tatsuya、Akira Shizuo、Beckham Wayne、Lorzadeh Alireza、Moksa Michelle、Cao Qi、Murthy Aditya、Hirst Martin、DeBerardinis Ralph J.、Lum Julian J.
    • Journal Title

      Cell Reports

      Volume: 27

    • DOI

      10.1016/j.celrep.2019.03.037

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Functional Correlation between Subcellular Localizations of Japanese Encephalitis Virus Capsid Protein and Virus Production2019

    • Author(s)
      Ishida Kotaro、Goto Simon、Ishimura Marina、Amanuma Misato、Hara Yumiko、Suzuki Ryosuke、Katoh Kaoru、Morita Eiji
    • Journal Title

      Journal of Virology

      Volume: 93 Pages: 00612-19

    • DOI

      10.1128/jvi.00612-19

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The activity of Sac1 across ER?TGN contact sites requires the four-phosphate-adaptor-protein-12019

    • Author(s)
      Venditti Rossella、Masone Maria Chiara、Rega Laura Rita、Di Tullio Giuseppe、Santoro Michele、Polishchuk Elena、Serrano Ivan Castello、Olkkonen Vesa M.、Harada Akihiro、Medina Diego L.、La Montagna Raffaele、De Matteis Maria Antonietta
    • Journal Title

      J Cell Biol

      Volume: 218 Pages: 783-797

    • DOI

      10.1083/jcb.201812021

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Beclin 1 regulates recycling endosome and is required for skin development in mice2019

    • Author(s)
      Noguchi Saori、Honda Shinya、Saitoh Tatsuya、Matsumura Hiroyuki、Nishimura Emi、Akira Shizuo、Shimizu Shigeomi
    • Journal Title

      Commun Biol.

      Volume: 2 Pages: 37-37

    • DOI

      10.1038/s42003-018-0279-0

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Paradigm shift from ‘Compartment’ to ‘Zone’ in the understanding of organelles2019

    • Author(s)
      Nishitoh Hideki
    • Journal Title

      J. Biochem.

      Volume: 165 Pages: 97-99

    • DOI

      10.1093/jb/mvy107

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Uric Acid-Induced Enhancements of Kv1.5 Protein Expression and Channel Activity via the Akt-HSF1-Hsp70 Pathway in HL-1 Atrial Myocytes2019

    • Author(s)
      Taufiq Fikri、Maharani Nani、Li Peili、Kurata Yasutaka、Ikeda Nobuhito、Kuwabara Masanari、Otani Naoyuki、Miake Junichiro、Hasegawa Akira、Tsuneto Motokazu、Shirayoshi Yasuaki、Ninomiya Haruaki、Saitoh Tatsuya、Nakai Akira、Yamamoto Kazuhiro、Hisatome Ichiro
    • Journal Title

      Circ J

      Volume: 83 Issue: 4 Pages: 718-726

    • DOI

      10.1253/circj.cj-18-1088

      10.1253/circj.CJ-18-1088

    • NAID

      130007620506

    • ISSN
      1346-9843, 1347-4820
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] NFAT5 up-regulates expression of the kidney-specific ubiquitin ligase gene Rnf183 under hypertonic conditions in inner-medullary collecting duct cells.2019

    • Author(s)
      Maeoka Y, Wu Y, Okamoto T, Kanemoto S, Guo XP, Saito A, Asada R, Matsuhisa K, Masaki T, Imaizumi K, Kaneko M.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 294 Pages: 101-115

    • DOI

      10.1074/jbc.ra118.002896

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] A Golgi-Released Subpopulation of the Trans-Golgi Network Mediates Protein Secretion in Arabidopsis2019

    • Author(s)
      Uemura Tomohiro、Nakano Ryohei Thomas、Takagi Junpei、Wang Yiming、Kramer Katharina、Finkemeier Iris、Nakagami Hirofumi、Tsuda Kenichi、Ueda Takashi、Schulze-Lefert Paul、Nakano Akihiko
    • Journal Title

      Plant Phys.

      Volume: 179 Pages: 519-532

    • DOI

      10.1104/pp.18.01228

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A Novel Contact by a Novel Protein Complex Supports Cholesterol Transport to the Endoplasmic Reticulum2018

    • Author(s)
      Harada Akihiro
    • Journal Title

      Contact

      Volume: 1 Pages: 251525641877968-251525641877968

    • DOI

      10.1177/2515256418779685

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution.2018

    • Author(s)
      Sobajima T., Yoshimura S*., Maeda T., Miyata H., Miyoshi E., and Harada A*. (*共同責任著者)
    • Journal Title

      J. Cell Biology

      Volume: pii: jcb.201709123 Pages: 1-15

    • DOI

      10.1083/jcb.201709123

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Nuclear envelope localization of PIG-B is essential for GPI-anchor synthesis in Drosophila2018

    • Author(s)
      Yamamoto-Hino Miki、Katsumata Eri、Suzuki Emiko、Maeda Yusuke、Kinoshita Taroh、Goto Satoshi
    • Journal Title

      Journal of Cell Science

      Volume: 131 Pages: 1-12

    • DOI

      10.1242/jcs.218024

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] A Collection of Transgenic Medaka Strains for Efficient Site-Directed Transgenesis Mediated by phiC31 Integrase2018

    • Author(s)
      Ishikawa Tokiro、Ansai Satoshi、Kinoshita Masato、Mori Kazutoshi
    • Journal Title

      G3; Genes|Genomes|Genetics

      Volume: 8 Pages: 2585-2593

    • DOI

      10.1534/g3.118.200130

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The binding of TBK1 to STING requires exocytic membrane traffic from the ER2018

    • Author(s)
      Ogawa Emari、Mukai Kojiro、Saito Kota、Arai Hiroyuki、Taguchi Tomohiko
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 503 Pages: 138-145

    • DOI

      10.1016/j.bbrc.2018.05.199

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling2018

    • Author(s)
      Hansen, A. L., Buchan, G. J., Ruhl, M., Mukai, K. et al.
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 115

    • DOI

      10.1073/pnas.1806239115

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development of a Series of Practical Fluorescent Chemical Tools To Measure pH Values in Living Samples2018

    • Author(s)
      Takahashi Shodai、Kagami Yu、Hanaoka Kenjiro、Terai Takuya、Komatsu Toru、Ueno Tasuku、Uchiyama Masanobu、Koyama-Honda Ikuko、Mizushima Noboru、Taguchi Tomohiko、Arai Hiroyuki、Nagano Tetsuo、Urano Yasuteru
    • Journal Title

      J Am Chem Soc

      Volume: 印刷中 Pages: 5925-5933

    • DOI

      10.1021/jacs.8b00277

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Membrane closure in stress induced-autophagosome formation.2018

    • Author(s)
      Eiji Morita
    • Journal Title

      Cell Stress

      Volume: 2 Pages: 122-124

    • DOI

      10.15698/cst2018.06.138

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unfolded Protein Response-Dependent Communication and Contact among Endoplasmic Reticulum, Mitochondria, and Plasma Membrane2018

    • Author(s)
      Saito Atsushi、Imaizumi Kazunori
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 19 Pages: 3215-3215

    • DOI

      10.3390/ijms19103215

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Shutdown of ER-associated degradation pathway rescues functions of mutant iduronate 2-sulfatase linked to mucopolysaccharidosis type II.2018

    • Author(s)
      Osaki Y, Saito A, Kanemoto S, Kaneko M, Matsuhisa K, Asada R, Masaki T, Orii K, Fukao T, Tomatsu S, Imaizumi K
    • Journal Title

      Cell Death & Disease

      Volume: 9 Pages: 808-808

    • DOI

      10.1038/s41419-018-0871-8

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Axonal Activation of the Unfolded Protein Response Promotes Axonal Regeneration Following Peripheral Nerve Injury.2018

    • Author(s)
      Ohtake Y, Matsuhisa K, Kaneko M, Kanemoto S, Asada R, Imaizumi K, Saito A.
    • Journal Title

      Neuroscience

      Volume: 375 Pages: 34-48

    • DOI

      10.1016/j.neuroscience.2018.02.003

    • Related Report
      2018 Annual Research Report 2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] RAB GTPases in the Basal Land Plant Marchantia polymorpha2018

    • Author(s)
      Minamino Naoki、Kanazawa Takehiko、Era Atsuko、Ebine Kazuo、Nakano Akihiko、Ueda Takashi
    • Journal Title

      Plant Cell Phys

      Volume: in press Pages: 845-856

    • DOI

      10.1093/pcp/pcy027

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Integration of two RAB5 groups during endosomal transport in plants2018

    • Author(s)
      Ito Emi、Ebine Kazuo、Choi Seung-won、Ichinose Sakura、Uemura Tomohiro、Nakano Akihiko、Ueda Takashi
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.34064

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Detailed Analysis of the Interaction of Yeast COG Complex2018

    • Author(s)
      Ishii Midori、Lupashin Vladimir V.、Nakano Akihiko
    • Journal Title

      Cell Struct. Funct.

      Volume: 43 Issue: 2 Pages: 119-127

    • DOI

      10.1247/csf.18014

    • NAID

      130007366858

    • ISSN
      0386-7196, 1347-3700
    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ANTH domain-containing proteins are required for the pollen tube plasma membrane integrity via recycling ANXUR kinases2018

    • Author(s)
      Muro Keita、Matsuura-Tokita Kumi、Tsukamoto Ryoko、Kanaoka Masahiro M.、Ebine Kazuo、Higashiyama Tetsuya、Nakano Akihiko、Ueda Takashi
    • Journal Title

      Commun. Biol.

      Volume: 1 Pages: 152-152

    • DOI

      10.1038/s42003-018-0158-8

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Dram1 regulates DNA damage-induced alternative autophagy2018

    • Author(s)
      Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, Honda S, Nishida Y, Konishi A, Shimizu S
    • Journal Title

      Cell stress

      Volume: 2 Pages: 55-65

    • DOI

      10.15698/cst2018.03.127

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Small fluorescent molecules for monitoring autophagic flux2018

    • Author(s)
      Iwashita Hidefumi、Sakurai Hajime Tajima、Nagahora Noriyoshi、Ishiyama Munetaka、Shioji Kosei、Sasamoto Kazumi、Okuma Kentaro、Shimizu Shigeomi、Ueno Yuichiro
    • Journal Title

      FEBS Letters

      Volume: 592 Pages: 559-567

    • DOI

      10.1002/1873-3468.12979

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Biological Roles of Alternative Autophagy2018

    • Author(s)
      Shigeomi Shimizu
    • Journal Title

      Mol. Cells

      Volume: 41 Pages: 50-54

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Autophagy limits activation of the inflammasomes2018

    • Author(s)
      Takahama Michihiro、Akira Shizuo、Saitoh Tatsuya
    • Journal Title

      Immunological Reviews

      Volume: 281 Pages: 62-73

    • DOI

      10.1111/imr.12613

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Sec16A, a key protein in COPII vesicle formation, regulates the stability and localization of the novel ubiquitin ligase RNF183.2018

    • Author(s)
      Wu Y, Guo XP, Kanemoto S, Maeoka Y, Saito A, Asada R, Matsuhisa K, Ohtake Y, Imaizumi K, Kaneko M.
    • Journal Title

      PLOS ONE

      Volume: 13

    • DOI

      10.1371/journal.pone.0190407

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma.2018

    • Author(s)
      Saito A, Cai L, Matsuhisa K, Ohtake Y, Kaneko M, Kanemoto S, Asada R, Imaizumi K.
    • Journal Title

      Journal of Neurochemistry

      Volume: 144 Pages: 35-49

    • DOI

      10.1111/jnc.14221

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy2018

    • Author(s)
      Shimasaki K, Watanabe-Takahashi M, Umeda M, Funamoto S, Saito Y, Noguchi N, Kumagai K, Hanada K, Tsukahara F, Maru Y, Shibata N, Naito M, Nishikawa K.
    • Journal Title

      Genes Cells

      Volume: 23 Pages: 22-34

    • DOI

      10.1111/gtc.12544

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Ribosome Incorporation into Somatic Cells Promotes Lineage Transdifferentiation towards Multipotency2018

    • Author(s)
      Ito Naofumi、Katoh Kaoru、Kushige Hiroko、Saito Yutaka、Umemoto Terumasa、Matsuzaki Yu、Kiyonari Hiroshi、Kobayashi Daiki、Soga Minami、Era Takumi、Araki Norie、Furuta Yasuhide、Suda Toshio、Kida Yasuyuki、Ohta Kunimasa
    • Journal Title

      Scientific Reports,

      Volume: 8 Pages: 1634-1634

    • DOI

      10.1038/s41598-018-20057-1

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Distinct sets of tethering complexes, SNARE complexes, and Rab GTPases mediate membrane fusion at the vacuole in Arabidopsis2018

    • Author(s)
      Takemoto Kodai、Ebine Kazuo、Askani Jana Christin、Kruger Falco、Gonzalez Zaida Andres、Ito Emi、Goh Tatsuaki、Schumacher Karin、Nakano Akihiko、Ueda Takashi
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 115

    • DOI

      10.1073/pnas.1717839115

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Brassinosteroids regulate vacuolar morphology in root meristem cells of Arabidopsis thaliana.2018

    • Author(s)
      Yamagami A, Saito C, Sakuta M, Shinozaki K, Osada H, Nakano A, Asami T, Nakano T
    • Journal Title

      Plant Signaling & Behavior

      Volume: 印刷中

    • DOI

      10.1080/15592324.2017.1417722

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] The Cellulose Synthases Are Cargo of the TPLATE Adaptor Complex2018

    • Author(s)
      Sanchez-Rodriguez Clara、Shi Yanyun、Kesten Christopher、Zhang Dongmei、Sancho-Andres Gloria、Ivakov Alexander、Lampugnani Edwin R.、Sklodowski Kamil、Fujimoto Masaru、Nakano Akihiko、Bacic Antony、Wallace Ian S.、Ueda Takashi、Van Damme Daniel、Zhou Yihua、Persson Staffan
    • Journal Title

      Molecular Plant

      Volume: 11 Pages: 346-349

    • DOI

      10.1016/j.molp.2017.11.012

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Golgi entry core compartment functions as the COPII-independent scaffold for ER-Golgi transport in plant cells2018

    • Author(s)
      Ito Yoko、Uemura Tomohiro、Nakano Akihiko
    • Journal Title

      J. Cell Sci.

      Volume: 131

    • DOI

      10.1242/jcs.203893

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A Missense Mutation in the <i>NSF</i> Gene Causes Abnormal Golgi Morphology in <i>Arabidopsis thaliana</i>2018

    • Author(s)
      Tanabashi Sayuri、Shoda Keiko、Saito Chieko、Sakamoto Tomoaki、Kurata Tetsuya、Uemura Tomohiro、Nakano Akihiko
    • Journal Title

      Cell Struct. Funct.

      Volume: 43 Issue: 1 Pages: 41-51

    • DOI

      10.1247/csf.17026

    • NAID

      130006565491

    • ISSN
      0386-7196, 1347-3700
    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Regulation of ER-Golgi Transport Dynamics by GTPases in Budding Yeast2018

    • Author(s)
      Suda Yasuyuki、Kurokawa Kazuo、Nakano Akihiko
    • Journal Title

      Frontiers Cell Dev. Biol.

      Volume: 5 Pages: 122-122

    • DOI

      10.3389/fcell.2017.00122

    • NAID

      120007128323

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Activation of Rab GTPase Sec4 by its GEF Sec2 is required for prospore membrane formation during sporulation in yeast Saccharomyces cerevisiae2018

    • Author(s)
      Suda Yasuyuki、Tachikawa Hiroyuki、Inoue Ichiro、Kurita Tomokazu、Saito Chieko、Kurokawa Kazuo、Nakano Akihiko、Irie Kenji
    • Journal Title

      FEMS Yeast Research

      Volume: 18 Pages: 1-1

    • DOI

      10.1093/femsyr/fox095

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Role of Atg5-dependent cell death in the embryonic development of Bax/Bak double-knockout mice2017

    • Author(s)
      Arakawa S, Tsujioka M, Yoshida T, Tajima-Sakurai H, Nishida Y, Matsuoka Y, Yoshino I, Tsujimoto Y, Shimizu S.
    • Journal Title

      Cell Death & Differentiation

      Volume: 9 Pages: 1598-1608

    • DOI

      10.1038/cdd.2017.84

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses2017

    • Author(s)
      Takahama Michihiro、Fukuda Mitsunori、Ohbayashi Norihiko、Kozaki Tatsuya、Misawa Takuma、Okamoto Toru、Matsuura Yoshiharu、Akira Shizuo、Saitoh Tatsuya
    • Journal Title

      Cell Rep

      Volume: 20 Pages: 2944-2954

    • DOI

      10.1016/j.celrep.2017.08.085

    • NAID

      120007134819

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] In Vitro Assay to Extract Specific Lipid Types from Phospholipid Membranes Using Lipid-Transfer Proteins: A Lesson from the Ceramide Transport Protein CERT2017

    • Author(s)
      Hanada Kentaro、Sugiki Toshihiko
    • Journal Title

      “Lipidomics” (Ed., Paul Wood). Series: Neuromethods

      Volume: 125 Pages: 81-98

    • DOI

      10.1007/978-1-4939-6946-3_6

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organelle Contact Sites2017

    • Author(s)
      Hanada Kentaro
    • Journal Title

      Advances in Experimental Medicine and Biology

      Volume: 997 Pages: 69-81

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evolutionarily conserved BIL4 suppresses the degradation of brassinosteroid receptor BRI1 and regulates cell elongation2017

    • Author(s)
      Yamagami Ayumi、Saito Chieko、Nakazawa Miki、Fujioka Shozo、Uemura Tomohiro、Matsui Minami、Sakuta Masaaki、Shinozaki Kazuo、Osada Hiroyuki、Nakano Akihiko、Asami Tadao、Nakano Takeshi
    • Journal Title

      Scientific Reports

      Volume: 7 Pages: 5739-5739

    • DOI

      10.1038/s41598-017-06016-2

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] MiR-199a inhibits secondary envelopment of Herpes Simplex Virus-1through the downregulation of Cdc42-specific GTPase activating protein localized in Golgi apparatus.2017

    • Author(s)
      2.Kobayashi, K., Suemasa, F., Sagara, H., Nakamura, S., Ino, Y., Kobayashi, K., Hiramatsu, H., Haraguchi, T., Kurokawa, K., Todo, T., Nakano, A., and Iba, H.
    • Journal Title

      Sci Rep

      Volume: 7 Pages: 6650-6650

    • DOI

      10.1038/s41598-017-06754-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Unfolded protein response transducer IRE1-mediated signaling independent of XBP1 mRNA splicing is not required for growth and development of medaka fish2017

    • Author(s)
      Tokiro Ishikawa, Makoto Kashima, Atsushi J Nagano, Tomoko Ishikawa-Fujiwara, Yasuhiro Kamei, Takeshi Todo, Kazutoshi Mori
    • Journal Title

      Elife

      Volume: 6:e26845 Pages: 1-29

    • DOI

      10.7554/elife.26845

    • NAID

      120006358815

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells.2017

    • Author(s)
      Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura SI, Natsume T, Miyamura N, Nishina H, Nakayama J, Semba K, Tomita T, Murata S, Arai H, Taguchi T.
    • Journal Title

      Nat Commun

      Volume: 8(1) Pages: 1246-1246

    • DOI

      10.1038/s41467-017-01255-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Omega-3 fatty acid epoxides are autocrine mediators that control the magnitude of IgE-mediated mast cell activation2017

    • Author(s)
      Shimanaka Yuta、Kono Nozomu、Taketomi Yoshitaka、Arita Makoto、Okayama Yoshimichi、Tanaka Yuki、Nishito Yasumasa、Mochizuki Tatsuki、Kusuhara Hiroyuki、Adibekian Alexander、Cravatt Benjamin F、Murakami Makoto、Arai Hiroyuki
    • Journal Title

      Nat Med

      Volume: 23 Pages: 1287-1297

    • DOI

      10.1038/nm.4417

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] The challenge to visualize vesicular trafficking in living cells by high-speed and super-resolution live imaging microscopy ;The dream has come true.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      Full-global kickoff symposium, Serendipity Lab.
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dynamics of the Golgi and its neighbors visualized by high-speed and super-resolution live imaging SCLIM.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      Symposium “Structure and Function of the Golgi,” 92nd Annual Meeting of the Japanese Biochemical Society
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] State-of-the-art live cell imaging at high-speed and super-resolution -- Dream to see real vesicular trafficking has come true.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      University of Oslo Seminar
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] State-of-the-art live cell imaging at high-speed and super-resolution -- Dream to see real vesicular trafficking has come true.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      University of Bergen Seminar
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] The identity of the trans-Golgi network revealed by super-resolution live imaging2019

    • Author(s)
      Takuro Tojima, Yasuyuki Suda, Midori Ishii, Kazuo Kurokawa, and Akihiko Nakano
    • Organizer
      Gordon Research Conference on Molecular Membrane Biology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The role of Atg8 in the regulation of vacuolar membrane homeostasis2019

    • Author(s)
      Ayane Ishii, Kazuo Kurokawa, Miyuu Hotta, Suzuka Yoshizaki, Maki Kurita, Aya Koyama, Akihiko Nakano, Yoko Kimura
    • Organizer
      Gordon Research Conference on Molecular Membrane Biology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Visualization of transmembrane cargo entry into the ERES in S. cerevisiae.2019

    • Author(s)
      Kazuo Kurokawa, Akihiko Nakano
    • Organizer
      Gordon Research Conference on Molecular Membrane Biology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] High-speed and super-resolution live imaging to understand the true world in a living cell.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      University of Michigan Seminar, Ann Arbor, MI, USA
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Extremely dynamic behaviors of vesicles and zones in an around the Golgi as visualized by high-speed super-resolution live imaging SCLIM.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      IAS Symposium “Biogenesis of Intracellular and Extracellular Vesicles,” Hong Kong
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] State-of-the-art live cell imaging at high-speed and super-resolution -- Dream to see real vesicular trafficking has come true.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      Joint Symposium “Extreme imaging to explore the boundaries between cell biology and protein science,” Joint Annual Meeting of 71st JSCB and 19th PSSJ
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Visualization of cargo transport from the ER to the Golgi and within the Golgi.2019

    • Author(s)
      Kazuo Kurokawa
    • Organizer
      RIKEN symposium: Cutting edge of membrane traffic
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Dynamics of protein sorting zones in and around the Golgi apparatus as visualized by high-speed super-resolution live imaging SCLIM.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      International Symposium “Organelle zones: opening a new ear of cell biology,”
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Dynamics of protein sorting zones within and around the Golgi apparatus as visualized by high-speed super-resolution live imaging SCLIM.2019

    • Author(s)
      Akihiko Nakano
    • Organizer
      SFB1190 Minisymposium “Organelle Zones Meet Compartmental Gates and Contact Sites,”
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The role of SNAP23 in the brain and the pancreas2019

    • Author(s)
      Akihiro Harada
    • Organizer
      Gordon conference: molecular membrane biology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Delivery of N-cadherin to the surface of neural stem cells is essential for development of the hippocampus and the cerebellum2019

    • Author(s)
      Akihiro Harada
    • Organizer
      International Conference of Developmental Biology, Stem Cells and Regenerative Medicine - Exploration and Integration
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation.2019

    • Author(s)
      Wu Y, Okamoto T, Imaizumi K, Kaneko M.
    • Organizer
      ASCB|EMBO2019 meeting, Washington, DC, USA
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Suppression of transcription factor OASIS ameliorated kidney fibrosis.2019

    • Author(s)
      Obana M, Yamamoto A, Nakae T, Miyake Y, Harada T, Mitsuoka S, Noda S, Maeda M, Imaizumi K, Matsumoto K, Fujio Y.
    • Organizer
      The American Society of Nephrology (ASN)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Multipleorganelle zones present in the endoplasmic reticulum.2019

    • Author(s)
      Kazutoshi Mori
    • Organizer
      International symposium on organelle zones: opening a new era of cell biology
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Roles of the unfolded protein response in cancer2019

    • Author(s)
      Kazutoshi Mori
    • Organizer
      Cancer Research UK Beatson International Cancer Conference “Protein Dynamics in Cancer”
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dynamics of function and regulation of the endoplasmic reticulum2019

    • Author(s)
      Kazutoshi Mori
    • Organizer
      iCeMS Retreat 2019 at Awaji Yumebutai
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Dynamics of function and regulation of the endoplasmic reticulum.2019

    • Author(s)
      Kazutoshi Mori
    • Organizer
      Scientific seminar
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Systematic development of natural ligand-nonmimetic inhibitors to the ceramide transport protein CERT2019

    • Author(s)
      Hanada Kentaro
    • Organizer
      FEBS special meeting in “Sphingolipid biology in health and disease”
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Hijacking of the ceramide transport protein CERT by Chlamydia trachomatis, an obligatory intracellular bacterium2019

    • Author(s)
      Hanada Kentaro
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Natural ligand-nonmimetic inhibitors of the lipid-transfer protein2019

    • Author(s)
      Sakai S, Nakao N, Ueno M, Egawa D, Hanzawa H, Kawasaki S, Kumagai K, Suzuki M, Kobayashi S, Hanada K
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chlamydia trachomatis requires host ceramide-transport protein CERT but not sphingomyelin synthases for the infection and proliferation in HeLa cells2019

    • Author(s)
      Kumagai K, Tachida Y, Sakai S, Yamaji T, Hanada K
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Structural basis for the specific association between the Chlamydia trachomatis inclusion membrane protein IncD and the PH domain of the ceramide transport protein CERT2019

    • Author(s)
      Sugiki T, Kumagai K, Shinya S, Kobayashi N, Egawa D, Fujiwara T, Hanada K, Kojima C
    • Organizer
      60th International Conference on the Bioscience of Lipids
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Observation of fine structures of the cell with optical microscopy2019

    • Author(s)
      Kaoru Katoh
    • Organizer
      Nikon Imaging Center Fluorescence Imaging Symposium
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Fine structures of the cells revealed with conventional and super resolution microscopy2019

    • Author(s)
      Kaoru Katoh, Minami Tanaka, Toutai Mitsuyama
    • Organizer
      The 6th International Symposium on Bioimaging
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Molecular mechanisms and physiological roles of Atg5-independent mitophagy2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      ASMRM & J-mit
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] New insights into the mechanism of Golgi-mediated alternative autophagy using chemical biology approach2019

    • Author(s)
      Shigeomi Shimizu
    • Organizer
      International Symposium of Autophagy
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] オートファジーと疾患2018

    • Author(s)
      清水重臣
    • Organizer
      第6回AAA会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Endogenous simian retrovirus variations in Vero cells: implications for quality control of a human vaccine cell substrate2018

    • Author(s)
      Sakuma C, Sekizuka T, Kuroda M, Kasai F, Saito K, Ikeda M, Yamaji T, Osada N, Hanada K
    • Organizer
      4th International Symposium of Medicinal Sciences
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Mechanistic analysis of mammalian ER-associated degradation2018

    • Author(s)
      Kazutoshi Mori
    • Organizer
      International Symposium on ER stress, glycosylation, homeostasis and diseases
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Dynamics of Function and Regulation of the Endoplasmic Reticulum2018

    • Author(s)
      Kazutoshi Mori
    • Organizer
      16th Asian Pacific Congress of Nephrology & 2018 Annual Congress of Chinese Society of Nephrology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] オートファジーが関わる細胞死2017

    • Author(s)
      清水重臣
    • Organizer
      日本Cell Death学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] 新規オートファジーの分子機構とその破綻による疾患2017

    • Author(s)
      清水重臣
    • Organizer
      第22回 日本病態プロテアーゼ学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Development of molecularly targeted anticancer agents based on the regulation of autophagic cell death2017

    • Author(s)
      清水重臣
    • Organizer
      第76回日本癌学会
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] The RAB2B-GARIL5 complex promotes cytosolic DNA-induced interferon responses2017

    • Author(s)
      Michihiro Takahama, Tatsuya Saitoh
    • Organizer
      American Society for Cell Biology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The roles of UPR signaling in the regulation of physiological functions2017

    • Author(s)
      Asada R, Imaizumi K
    • Organizer
      Washington University School of Medicine Research Seminar
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Axon Regeneration Promoted by Signaling of the Unfolded Protein Response in Peripheral Nerve Injury2017

    • Author(s)
      Ohtake Y, Saito A, Imaizumi K
    • Organizer
      Society for Neuroscience 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Dendritic expansion and spine formation regulated by signaling pathways of unfolded protein response2017

    • Author(s)
      Saito A, Imaizumi K
    • Organizer
      Society for Neuroscience 2017
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Skeletal cell differentiation and tissue formation regulated by endoplasmic reticulum-derived signaling2017

    • Author(s)
      Saito A, Imaizumi K
    • Organizer
      The 14th Bone Biology Forum
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Membrane traffic unveiled by super-resolution live imaging: expectations for exosome research.2017

    • Author(s)
      Nakano, A.
    • Organizer
      9th Annual Meeting of the Japanese Association for RNAi and 4th Annual Meeting of Japanese Society of Extracellular Vesicles
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] "4D Imaging of Cargo Delivery in Maturating Golgi Cisternae in S. cerevisiae"Regulation of Ways of Communication-From Molecules to Organisms2017

    • Author(s)
      Kazuo Kurokawa
    • Organizer
      Molecular Membrane Biology, Gordon Research Conferences
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The molecular mechanism of apical transport in the mouse intestinal epithelial cells: The role of Rabs and their binding proteins2017

    • Author(s)
      Akihiro Harada
    • Organizer
      EMBO conference ‘Cell polarity and membrane dynamics'
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The role of SNAP23 in secretion2017

    • Author(s)
      Masataka Kunii and Akihiro Harada
    • Organizer
      Gordon Research Conference ‘Molecular Membrane Biology’
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Rab11a GTPase regulates apical protein localization and microvilli formation in the intestine2017

    • Author(s)
      Sobajima,Tomoaki, Shin-ichiro Yoshimura and Akihiro Harada
    • Organizer
      Gordon Research Conference ‘Molecular Membrane Biology’
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The unfolded protein response : to mammals and beyond2017

    • Author(s)
      Kazutoshi Mori
    • Organizer
      Endoplasmic Reticulum Functions in Physiology and Pathology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Book] “Conventional, apodized and relief phase-contrast microscopy” in book: Neurohistology and Imaging Techniques (Neuromethods, vol. 153)2020

    • Author(s)
      Pelc, R., Hostounsk&yacute; , Z., Otaki, T., Katoh, K.
    • Total Pages
      471
    • Publisher
      Springer (Humana Press)
    • ISBN
      9781071604267
    • Related Report
      2019 Annual Research Report
  • [Remarks] オルガネラゾーンホームページ

    • URL

      http://organellezone.org/

    • Related Report
      2020 Annual Research Report
  • [Remarks] オルガネラゾーン ホームページ

    • URL

      http://organellezone.org/

    • Related Report
      2019 Annual Research Report
  • [Remarks] 細胞機能を司る オルガネラ・ゾーンの解読 ホームページ

    • URL

      http://organellezone.org/

    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] ペプチド、それを含む小胞体ストレスマーカー及びそれを用いた小胞体ストレスの測定方法2017

    • Inventor(s)
      今泉和則, 齋藤敦, 松久幸司
    • Industrial Property Rights Holder
      今泉和則, 齋藤敦, 松久幸司
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-150714
    • Filing Date
      2017
    • Related Report
      2017 Annual Research Report
  • [Patent(Industrial Property Rights)] BBF2H7(BBF2 human homologue on chromosome7)部分アミノ酸配列を有するペプチドまたはそれに結合する抗体を含む細胞増殖調節用組成物2017

    • Inventor(s)
      今泉和則, 齋藤敦
    • Industrial Property Rights Holder
      今泉和則, 齋藤敦
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Acquisition Date
      2017
    • Related Report
      2017 Annual Research Report
    • Overseas
  • [Funded Workshop] Organelle zones: opening a new era of cell biology2019

    • Related Report
      2019 Annual Research Report

URL: 

Published: 2017-07-04   Modified: 2022-12-28  

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