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Hybrid Catalysis for Enabling Molecular Synthesis on Demand

Administrative Group

Project AreaHybrid Catalysis for Enabling Molecular Synthesis on Demand
Project/Area Number 17H06441
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Science and Engineering
Research InstitutionThe University of Tokyo

Principal Investigator

Kanai Motomu  東京大学, 大学院薬学系研究科(薬学部), 教授 (20243264)

Project Period (FY) 2017-06-30 – 2022-03-31
Project Status Completed (Fiscal Year 2022)
Budget Amount *help
¥69,290,000 (Direct Cost: ¥53,300,000、Indirect Cost: ¥15,990,000)
Fiscal Year 2021: ¥13,650,000 (Direct Cost: ¥10,500,000、Indirect Cost: ¥3,150,000)
Fiscal Year 2020: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2019: ¥12,610,000 (Direct Cost: ¥9,700,000、Indirect Cost: ¥2,910,000)
Fiscal Year 2018: ¥15,600,000 (Direct Cost: ¥12,000,000、Indirect Cost: ¥3,600,000)
Fiscal Year 2017: ¥14,820,000 (Direct Cost: ¥11,400,000、Indirect Cost: ¥3,420,000)
Keywords触媒 / 有機合成化学 / ハイブリッド触媒 / 均一系触媒 / 固体触媒 / 高分子化学 / 天然物合成 / ドミノ触媒 / 高分子 / 医薬リード / 理論科学 / 分子合成オンデマンド / 触媒化学 / 光化学 / 不斉合成 / 天然物合成化学 / 触媒・化学プロセス / 分子活性種発生 / 高次反応制御 / 超効率分子合成 / 合成化学 / ハイブリッド触媒系
Outline of Final Research Achievements

Many of the substances indispensable for the enrichment of human health and culture are composed of organic molecules. Synthetic organic chemistry is the only way to create and stably supply these substances. Although synthetic organic chemistry has made progress, it is still difficult to supply the necessary organic molecules in the required quantities with the current capabilities. To solve this problem, we have created hybrid catalyst systems that utilize the function of multiple catalysts in a concerted manner, and have pioneered extremely efficient organic synthetic reactions that, if realized, would have a great impact but were not possible in the past. As a result, we have realized a molecular synthesis-on-demand that rapidly assembles value-added, complex organic molecules from simple, readily available raw materials according to demand.

Academic Significance and Societal Importance of the Research Achievements

個別に発展してきた有機触媒、金属錯体触媒、不斉触媒、光触媒、固体触媒といった触媒化学分野に加えて、物理化学、理論科学、高分子化学、天然物合成化学に携わる多分野の研究者を結集し、ハイブリット触媒系の創製に焦点を絞った研究を複合的かつ強力に推進した点で学術的意義がある。これにより本領域は、今後発展が大きく期待される有機合成化学分野の研究を、国内外を問わず先導し、新たな潮流を創り出してきた。また、単純で入手容易な有機分子から高付加価値の有機分子を、環境負荷を低減しながら地球規模で供給する触媒システムの創製を実現してきたところに社会的意義がある。

Report

(6 results)
  • 2022 Final Research Report ( PDF )
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (29 results)

All 2022 2021 2019 2018 Other

All Int'l Joint Research (12 results) Presentation (4 results) (of which Invited: 1 results) Remarks (3 results) Funded Workshop (10 results)

  • [Int'l Joint Research] SIOC/大連理工大学/Lanzhou University(中国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] PSL Research University/Universite de Toulouse/University Grenoble Alps(フランス)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University of California, Berkeley/Purdue University/Johns Hopkins University(米国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] University College of London(英国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] POSTECH/梨花女子大学(韓国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] IMDEA nanoscience(スペイン)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] 南洋工科大(シンガポール)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] 香港大学(香港)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] マルセイユ大(フランス)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] テキサス大学(米国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research]

    • Related Report
      2017 Annual Research Report
  • [Presentation] opening remarks2019

    • Author(s)
      金井求
    • Organizer
      日本化学会年会、甲南大:化学会特別企画「システム志向の触媒化学」(略称:触媒システム化学)
    • Related Report
      2018 Annual Research Report
  • [Presentation] 旗艦たる触媒化学の創造を求めて2018

    • Author(s)
      金井求
    • Organizer
      第1回「ハイブリッド触媒」若手道場
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] 開会挨拶2018

    • Author(s)
      金井求
    • Organizer
      化学フェスタ、文科省科研費新学術領域研究「ハイブリッド触媒」特別企画:「1+1は3?」ハイブリッド触媒が紡ぎ出す新反応化学
    • Related Report
      2018 Annual Research Report
  • [Presentation] 開会挨拶2018

    • Author(s)
      金井求
    • Organizer
      第2回 「ハイブリッド触媒」公開シンポジウム
    • Related Report
      2018 Annual Research Report
  • [Remarks] ハイブリッド触媒HP

    • URL

      https://gousei.f.u-tokyo.ac.jp/hybridcatalysis/

    • Related Report
      2021 Annual Research Report
  • [Remarks] ハイブリッド触媒領域ホームページ

    • URL

      http://hybridcatalysis.jp/

    • Related Report
      2020 Annual Research Report 2019 Annual Research Report 2018 Annual Research Report
  • [Remarks] 分子合成オンデマンドを実現するハイブリッド触媒系の創製「ハイブリッド触媒」

    • URL

      http://hybridcatalysis.jp/

    • Related Report
      2017 Annual Research Report
  • [Funded Workshop] The 3rd International Symposium on Hybrid Catalysis for Enabling Molecular Synthesis on Demand2022

    • Related Report
      2021 Annual Research Report
  • [Funded Workshop] 第2回ハイブリッド触媒国際シンポジウム2021

    • Related Report
      2020 Annual Research Report
  • [Funded Workshop] 第1回ハイブリッド触媒国際会議2019

    • Related Report
      2019 Annual Research Report
  • [Funded Workshop] Japanese-Spanish Pre-Symposium in Organic Synthesis in Sendai2018

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] The Second Japanese-Spanish Symposium in Organic Synthesis2018

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] Japanese-Spanish Post-Symposium in Organic Synthesis in Nagoya2018

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] Japanese-Spanish Post-Symposium in Organic Synthesis in Tokyo2018

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] 第6回日英不斉触媒シンポジウム2018

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] International Symposium on Catalysis and Fine Chemicals2018

    • Related Report
      2018 Annual Research Report
  • [Funded Workshop] Young Researchers’ Meeting with Professor Nicolaou2018

    • Related Report
      2018 Annual Research Report

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Published: 2017-07-04   Modified: 2024-01-30  

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