YAMATO Osamu Graduate School of Veterinary Lecturer, 大学院・獣医学研究科, 講師 (80261337)
MAEDA Yoshimitsu Graduate School of Veterinary Professor, 大学院・獣医学研究科, 教授 (40002084)
TAHARA Satoshi Graduate School of Agriculture Professor, 大学院・農学研究科, 教授 (50001475)
KATAKURA Ken Gunma University, School of Medical Associate Professor, 医学部, 助教授 (10130155)
SUZUKI Mamoru Gunma University, School of Medical Professor, 医学部, 教授 (60056033)
|Budget Amount *help
¥12,200,000 (Direct Cost: ¥12,200,000)
Fiscal Year 2002: ¥5,200,000 (Direct Cost: ¥5,200,000)
Fiscal Year 2001: ¥7,000,000 (Direct Cost: ¥7,000,000)
The first survey : Aug 3, 〜Aug 7, 2001 Survey was done at the place near Palangkaraya in Central Kalimantan. Twenty seven anti-malaria plants were collected. The determination of species was done by the researchers of LIPI.
The second survey : Dec 14, 〜Dec 23, 2002 Survey was done at the place near Palembang and Lampung in South Sumatera. Eveven plants were collected.
Anti Babesia compounds were isolated from the plants according to the bioassay of Babesia gibsoni. Phyllanthus niruri : Pentahydroxyxanthon, Ellagic acid glucopyranoside, Arcangelisia flava : Berberine, 20-Hydroxy ecdisone Peronema canescens : Peronemin A3, Quercetin glucopyranoside Garcinia celebica : Catechine, Catechine dimer Shorea balangeran : Vaticanol A, B, G Garacinia rigida : Mangostin Curcuma zedoaria : Zedoalactone B, C Cinnamomum sintoc : 1-allyl-3,4-dimethyl benzene, 1-allyl-3,5-dimethoxy phenol, euqenol, innamaldehyde, cinnamic acid, cinnamyl alcohol, 3-(4-hydroxy-3-methoxy phenyl)-propenal, vanillin, sitosterol, 2,3-Bis-(4-hydroxy-3-methoxy-benzyl)-butane-1,4-diol)
Berberin from A-flava and mangostin from G-rigida showed the high anti-malaria adtizities. These two plants are effutive, as medical plants.