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The feasibility dynamic analysis of coronary subtraction using 320 row detector CT

Research Project

Project/Area Number 16K09023
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Medical Physics and Radiological Technology
Research InstitutionSaitama Medical University (2017-2019)
Tokyo Women's Medical University (2016)

Principal Investigator

Fukushima Kenji  埼玉医科大学, 医学部, 准教授 (50408613)

Co-Investigator(Kenkyū-buntansha) 阿部 光一郎  東京女子医科大学, 医学部, 教授 (00380387)
久慈 一英  埼玉医科大学, 医学部, 教授 (90283142)
百瀬 満  東京女子医科大学, 医学部, 非常勤講師 (40312029)
山根 登茂彦  埼玉医科大学, 医学部, 准教授 (20526660)
坂井 修二  東京女子医科大学, 医学部, 教授 (90225756)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2018: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords冠動脈 / CT / ダイナミック / サブトラクション / 虚血性心疾患 / 冠動脈疾患 / 冠動脈硬化 / CTサブトラクション / 冠動脈血流 / 冠動脈CT / 心筋血流PET
Outline of Final Research Achievements

The utility of coronary subtraction using 320 row detector CT is currently under investigation. The analyses were almost done for primal investigation, and statistical analysis is undertaken. Dynamic analyses using CT data during dynamic acquisition were also performed. Significant change of CT value was associated with flow reduction or myocardial ischemia.

Academic Significance and Societal Importance of the Research Achievements

冠動脈CT検査は有用であるが、動脈硬化が高度になると冠動脈石灰化で評価困難になることが多い。単純CTを用いて造影画像から石灰化を除去する技術を用いて冠動脈狭窄評価を行う手法があるが、従来の手法と異なりダイナミック撮像を併用することで、冠動脈血流低下を予測する手法を開発することである。特にダイナミック撮像からのデータ解析は有用と考えられ、血流低下や心筋虚血などの診断に貢献できる可能性が期待される。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (10 results)

All 2020 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (9 results) (of which Int'l Joint Research: 4 results,  Invited: 5 results)

  • [Journal Article] Patient Based Bull?s Eye Map Display of Coronary Artery and Ventricles From Coronary Computed Tomography Angiography2020

    • Author(s)
      Fukushima Kenji、Matsuo Yuka、Nagao Michinobu、Sakai Akiko、Kihara Nobuyuki、Onishi Koji、Sakai Shuji
    • Journal Title

      Journal of Computer Assisted Tomography

      Volume: 44 Issue: 1 Pages: 26-31

    • DOI

      10.1097/rct.0000000000000966

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Presentation] Patient Based Territorial Coronary Flow Analysis by Voronoi Algorithm With 13N Ammonia PET CTA Fusion2017

    • Author(s)
      Kenji Fukushima
    • Organizer
      American College of Cardiology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Cardiac Diffusion Weighted Image in Patients With Cardiac Sarcoidosis: Comparison to 18F-fludeoxyglcose PET2017

    • Author(s)
      Kenji Fukushima
    • Organizer
      American College of Cardiology
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Coronary Flow Quantification Using Dynamic 320-detector CT Angiography With Motion Coherence Image Processing; Comparison To Trans Attenuation Gradient2017

    • Author(s)
      Kenji Fukushima
    • Organizer
      Society of Cardiovascular Computed Tomography
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] PCI最適化に必要なPET・SPECTの知識2017

    • Author(s)
      福島 賢慈
    • Organizer
      日本心臓病学会総会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] I-123BMIPPを用いた心臓サルコイドーシスの診断とモニタリング2017

    • Author(s)
      福島 賢慈
    • Organizer
      日本核医学会総会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 循環器診療に核医学を活かす(心筋症、その他)2017

    • Author(s)
      福島 賢慈
    • Organizer
      日本循環器学会総会
    • Related Report
      2017 Research-status Report
    • Invited
  • [Presentation] 心臓PETの臨床応用への導入とその課題2016

    • Author(s)
      福島賢慈
    • Organizer
      日本核医学会総会
    • Place of Presentation
      愛知県名古屋市
    • Year and Date
      2016-11-04
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] CardioREPOによる虚血評価の有用性2016

    • Author(s)
      福島賢慈
    • Organizer
      日本心臓核医学会
    • Place of Presentation
      三重県津市
    • Year and Date
      2016-07-15
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] The Relation of Myocardial and extra-myocardial inflammation in patients with cardiac sarcoidosis2016

    • Author(s)
      Kenji Fukushima
    • Organizer
      Society of Nuclear Medicine
    • Place of Presentation
      Washington D.C.
    • Year and Date
      2016-06-11
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2016-04-21   Modified: 2021-02-19  

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