|Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2018: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|Outline of Final Research Achievements
Using adhesive (as follows biobond) derived from a plant, I proved the biocompatibility for the bone and performed a study to inspect possibility as adhesive for the world's first osteosynthesis. The biobond was superior to biocompatibility as adhesive, and the inflammatory reaction was control and a result not to change at all, but when it was hydrophilic and was poor, and blood and an exudate invaded it between a bone and bond, adhesive strength was remarkable and decreased, and the fixation as I could endure bone fracture treatment was not provided. The improvement to add a hydrophilic group to biobond in itself increased it, but adhesive property in itself decreased, and it was thought that the practical use was difficult.