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Verification of a novel protocol of eating/swallowing functions for Down syndrome patients with risk of premature aging

Research Project

Project/Area Number 16K11870
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionThe Nippon Dental University

Principal Investigator

MIZUKAMI MIKI  日本歯科大学, 生命歯学部, 医療職員 (60735695)

Co-Investigator(Kenkyū-buntansha) 菊谷 武  日本歯科大学, 生命歯学部, 教授 (20214744)
松山 美和  徳島大学, 大学院医歯薬学研究部(歯学域), 教授 (30253462)
田村 文誉  日本歯科大学, 生命歯学部, 教授 (60297017)
Project Period (FY) 2016-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2019: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2018: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsダウン症候群 / 摂食嚥下障害 / 咀嚼機能 / 粗大運動 / 摂食嚥下機能障害 / 嚥下機能 / 摂食嚥下機能不全段階 / 歯学 / リハビリテーション / 臨床
Outline of Final Research Achievements

Down syndrome (DS) is has the highest prevalence syndrome in newborns with of any chromosomal abnormalitiesy identified in newborns. Moreover, DSDown syndrome children are also at has a high risk of aspiration., and sSwallowing food without chewing is considered to be a factor associated with increased risk of aspiration and eating problems. We investigated the factors related to masticatory function in DS children for development of a novel in order to create a new protocol specialized for DSDown syndrome. The subjects were 75 outpatient DS children, (age 12 to 36 month-old).
As a result, the revealed age, low birth weight, picky eating, and gross motor function were to be relevant factors. Among these factors, gross motor function had was found to be the factor the strongest most strongly relevance associated with acquisition of masticatory function.

Academic Significance and Societal Importance of the Research Achievements

染色体疾患の中で最も患者数の多いダウン症候群は、誤嚥のリスクが高い疾患である。誤嚥のリスクを高めている要因が、ダウン症候群の特徴でもある丸のみ(咀嚼機能不全)や早期退行現象の出現などがあげられる。我々は、誤嚥や食事に関するリスクを高めている要因の1つである丸のみに注目し、新たなダウン症候群に特化したプロトコールを作成するために咀嚼機能に関連する要因を検討した。
その結果、12~36か月のダウン症候群では、咀嚼機能の獲得の有無と関連のあった項目は、年齢、低出生、偏食、粗大運動であり、これらの中でも最も関連の強かったものが粗大運動であった。

Report

(5 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • 2016 Research-status Report
  • Research Products

    (15 results)

All 2019 2018 2017

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results) Presentation (7 results) (of which Int'l Joint Research: 2 results) Book (6 results)

  • [Journal Article] Investigating factors related to the acquisition of masticatory function in Down Syndrome children2019

    • Author(s)
      Mizukami M,Kikutani T,Matsuyama M,Nagashima K,Isoda T,Tamura F
    • Journal Title

      International Journal of Orofacial Myology

      Volume: 45 Pages: 46-56

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 発達期摂食嚥下障害児(者)のための嚥下調整食分類20182018

    • Author(s)
      浅野一恵,小城明子,近藤和泉,鈴木崇之,曽根翠,藤谷順子,水上美樹,向井美惠,弘中祥司,武原格
    • Journal Title

      日摂食嚥下リハ会誌

      Volume: 22 Pages: 59-73

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Presentation] Investigating factors related to the acquisition of masticatory function in Down syndrome children2019

    • Author(s)
      Mizukami M,, Tamura F,Matsuyama M, Nishizawa K,Tanaka Y,Kikuchi M, Kikutani T
    • Organizer
      Asia Association for Disability and Oral Health
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 摂食嚥下障害児がかかえる偏食と感覚過敏の問題2018

    • Author(s)
      水上美樹
    • Organizer
      日本摂食嚥下リハビリテーション学会学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] オンライン医療による小児患者への摂食指導の試み2018

    • Author(s)
      永島圭悟,田村文誉,水上美樹,古屋裕康,町田麗子,菊谷 武
    • Organizer
      障害者歯科学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 口腔リハビリテーションクリニックにおける偏食を有する障害児の実態調査2018

    • Author(s)
      田中祐子,田村文誉,松山美和,山田裕之,保母妃美子,礒田友子,永島圭悟,水上美樹,
    • Organizer
      障害者歯科学会
    • Related Report
      2018 Research-status Report
  • [Presentation] 遠隔診療による摂食指導の小児患者への試み2018

    • Author(s)
      田村文誉,永島圭悟,水上美樹,古屋裕康,町田麗子,菊谷 武
    • Organizer
      日本摂食嚥下リハビリテーション学会
    • Related Report
      2018 Research-status Report
  • [Presentation] Developmental problems concerning children’s oral function, based on a2018

    • Author(s)
      Tamura F, Yamada H, Kikutani T
    • Organizer
      Annual IAOM Convention
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] ダウン症候群児に特化した摂食機能プロトコールの開発にむけての取り組み2017

    • Author(s)
      水上 美樹
    • Organizer
      障害者歯科学会
    • Related Report
      2017 Research-status Report
  • [Book] 摂食嚥下機能の発達とその障害 1)摂食嚥下機能の正常発達2018

    • Author(s)
      水上美樹
    • Total Pages
      5
    • Publisher
      臨床栄養
    • Related Report
      2018 Research-status Report
  • [Book] 歯科衛生士が知っておきたい対象像の評価と管理2018

    • Author(s)
      水上美樹
    • Total Pages
      7
    • Publisher
      デンタルハイジーン
    • Related Report
      2018 Research-status Report
  • [Book] 発達期摂食嚥下障害児(者)のための嚥下調整食分類2018-有効活用に向け2018

    • Author(s)
      水上美樹
    • Total Pages
      5
    • Publisher
      臨床栄養
    • Related Report
      2018 Research-status Report
  • [Book] 子どもの「食べる楽しみ」を支援する 子どもの摂食嚥下の具体的なアセスメントの実際2018

    • Author(s)
      田村文誉
    • Total Pages
      11
    • Publisher
      建帛社
    • ISBN
      9784767961941
    • Related Report
      2018 Research-status Report
  • [Book] 小児の口腔機能発達評価マニュアルを応用した口腔機能発達の支援~食べ方・栄養編~2018

    • Author(s)
      田村文誉,水上美樹
    • Total Pages
      8
    • Publisher
      日本歯科医師会
    • Related Report
      2018 Research-status Report
  • [Book] 日本歯科医師会雑誌2018

    • Author(s)
      田村文誉,水上美樹
    • Total Pages
      8
    • Publisher
      身近な臨床・これからの歯科医のための臨床講座,小児の口腔機能発達評価マニュアル
    • Related Report
      2018 Research-status Report

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Published: 2016-04-21   Modified: 2021-02-19  

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