| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2018: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
|---|
| Outline of Final Research Achievements |
Bacterial pathogens deliver effector proteins into plant cells by type III secretion system. The effectors strongly suppress host immune responses as the virulence factors. Therefore, natural products that can inhibit formation of type III secretion system are useful for disease control. To screen such natural products from actinomycete secondary metabolites, we developed a system to monitor expression of the genes involved in formation of type III secretion system and found the candidate metabolites that can suppress the type III secretion system.
|
