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Molecular Communication: Standardization and Application Development

Research Project

Project/Area Number 17H00733
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Information network
Research InstitutionOsaka City University (2020-2021)
Osaka University (2017-2019, 2021)

Principal Investigator

Nakano Tadashi  大阪市立大学, 大学院工学研究科, 教授 (70571173)

Project Period (FY) 2017-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥43,290,000 (Direct Cost: ¥33,300,000、Indirect Cost: ¥9,990,000)
Fiscal Year 2021: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2020: ¥8,320,000 (Direct Cost: ¥6,400,000、Indirect Cost: ¥1,920,000)
Fiscal Year 2019: ¥7,670,000 (Direct Cost: ¥5,900,000、Indirect Cost: ¥1,770,000)
Fiscal Year 2018: ¥9,100,000 (Direct Cost: ¥7,000,000、Indirect Cost: ¥2,100,000)
Fiscal Year 2017: ¥10,530,000 (Direct Cost: ¥8,100,000、Indirect Cost: ¥2,430,000)
Keywords分子通信 / 情報ネットワーク / ナノ医療 / 生命科学 / 構造形成 / がん細胞 / 情報通信工学 / ネットワーク / センサネットワーク / 通信方式 / ドラッグデリバリ
Outline of Final Research Achievements

Molecular communication is a biologically inspired communication paradigm in which biological molecules are used to transmit information. In this project, we aimed to establish molecular communication as a communication technology and developed methods and systems of molecular communication. Toward the goal, we have developed methods of molecular communication to transmit information using chemical waves. We have also devised the concept of mobile molecular communication, molecular communication among mobile bio-nanomachines. We have also designed and developed cooperative drug delivery systems where a group of bio-nanomachines communicate using molecular communication to detect and delivery drug molecules to target locations. Further, we have modelled and analyzed systems of cancer cells that interact through molecular communication and form a large-scale structure. Research results obtained in this research project will form the basis of future molecular communication research.

Academic Significance and Societal Importance of the Research Achievements

本研究の成果をまとめた論文は、情報通信分野で世界的に権威のある国際学術論文誌 (PIEEEなど)に採択されたり、大規模な国際会議(IEEE GLOBECOM 2020)において最優秀論文賞を受賞したりするなど、学術的に高い評価を得ている。さらに、がん細胞生物学と関連する研究の成果については、生物物理学分野で権威のある学術雑誌にも採択され、一般にも広く報道された。本研究の成果は新しい通信技術の開発につながるだけでなく、生物学や医学の進展にも貢献することが期待される。

Report

(5 results)
  • 2021 Final Research Report ( PDF )
  • 2020 Annual Research Report
  • 2019 Annual Research Report
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (39 results)

All 2022 2020 2019 2018 2017 Other

All Int'l Joint Research (9 results) Journal Article (8 results) (of which Int'l Joint Research: 6 results,  Peer Reviewed: 8 results,  Open Access: 1 results) Presentation (20 results) (of which Int'l Joint Research: 19 results,  Invited: 5 results) Remarks (2 results)

  • [Int'l Joint Research] 同済大学/中国科技大学/重慶郵電大学(中国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] エセックス大学(英国)

    • Related Report
      2019 Annual Research Report
  • [Int'l Joint Research] 電子科技大学(中国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] Waikato University(ニュージーランド)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Massachusetts, Boston/University Net. Group(米国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] University of Essex(英国)

    • Related Report
      2018 Annual Research Report
  • [Int'l Joint Research] 電子科技大学(中国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] Cambridge University/University of Essex(英国)

    • Related Report
      2017 Annual Research Report
  • [Int'l Joint Research] University Net Group(米国)

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Bionanomachine Diagnostics and Nanonetwork Therapeutic in Brain Malignancies With Bionanodevice Interfaces2022

    • Author(s)
      Andreani D. Odysseos and Tadashi Nakano
    • Journal Title

      IEEE TRANSACTIONS ON MOLECULAR, BIOLOGICAL, AND MULTI-SCALE COMMUNICATIONS

      Volume: 8 Issue: 1 Pages: 28-35

    • DOI

      10.1109/tmbmc.2021.3083725

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Roles of Remote and Contact Forces in Epithelial Cell Structure Formation2020

    • Author(s)
      Nakano Tadashi、Okaie Yutaka、Kinugasa Yasuha、Koujin Takako、Suda Tatsuya、Hiraoka Yasushi、Haraguchi Tokuko
    • Journal Title

      Biophysical Journal

      Volume: 118 Issue: 6 Pages: 1466-1478

    • DOI

      10.1016/j.bpj.2020.01.037

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Random Cell Motion Enhances the Capacity of Cell-cell Communication2019

    • Author(s)
      T. Nakano, L. Lin, Y. Okaie, C. Wu, H. Yan, T. Hara, and K. Harumoto
    • Journal Title

      IEEE Transactions on Molecular, Biological and Multiscale Communications

      Volume: 5 Issue: 2 Pages: 158-162

    • DOI

      10.1109/tmbmc.2020.2983909

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Methods and Applications of Mobile Molecular Communication2019

    • Author(s)
      T. Nakano, Y. Okaie, S. Kobayashi, T. Hara, Y. Hiraoka, and T. Haraguchi
    • Journal Title

      Proceedings of the IEEE

      Volume: 107 Issue: 7 Pages: 1442-1456

    • DOI

      10.1109/jproc.2019.2917625

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Molecular communication: A personal perspective2018

    • Author(s)
      T. Suda and T. Nakano
    • Journal Title

      IEEE Transactions on Nanobioscience

      Volume: 17 Issue: 4 Pages: 424-432

    • DOI

      10.1109/tnb.2018.2851951

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Graph-based Modeling of Mobile Molecular Communication Systems2018

    • Author(s)
      S. Iwasaki and T. Nakano
    • Journal Title

      IEEE Communications Letters

      Volume: 22 Issue: 2 Pages: 376-379

    • DOI

      10.1109/lcomm.2017.2765628

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stochastic Channel Switching of Frequency-encoded Signals in Molecular Communication Networks2018

    • Author(s)
      P. He, T. Nakano, P. Lio’, Y. Mao, Q. Liu and K. Yang
    • Journal Title

      IEEE Communications Letters

      Volume: 22 Issue: 2 Pages: 332-335

    • DOI

      10.1109/lcomm.2017.2768537

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Molecular Communication Using Dynamic Properties of Oscillating and Propagating Patterns in Concentration of Information Molecules2017

    • Author(s)
      T. Nakano and T. Suda
    • Journal Title

      IEEE Transactions on Communications

      Volume: 65 Pages: 3386-3398

    • DOI

      10.1109/tcomm.2017.2700856

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Growing Bio-nanomachine Networks: Application to Malignant Tumor Evolution and Progression2020

    • Author(s)
      Tadashi Nakano, Yutaka Okaie, Nikolaos Dietis, Andreani D. Odysseos
    • Organizer
      IEEE Global Communications Conference (IEEE GLOBECOM 2020)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Communication, Migration and Energy in Bio-nanomachine Functionality Differentiation2020

    • Author(s)
      Tadashi Nakano, Tatsuya Suda
    • Organizer
      IEEE Global Communications Conference (IEEE GLOBECOM 2020)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cooperative Signaling and Di- rected Migration of Bio-nanomachines in Mobile Molecular Communication2020

    • Author(s)
      S. Ishiyama, T. Nakano, Y. Okaie, T. Hara, and K. Harumoto
    • Organizer
      7th ACM International Conference on Nanoscale Computing and Communication (ACM NANOCOM 2020)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Network Formation Model of Bio-nanomachines Based on Directed Migration and Adhesion2020

    • Author(s)
      K. Yonekura, T. Nakano, Y. Okaie, T. Hara, and K. Harumoto
    • Organizer
      EEE Wireless Communications and Networking Conference (IEEE WCNC 2020)
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Network Formation Model of Bio-nanomachines Based on Directed Migration and Adhesion2020

    • Author(s)
      K. Yonekura, T. Nakano, Y. Okaie, T. Hara, and K. Harumoto
    • Organizer
      IEEE Wireless Communications and Networking Conference (IEEE WCNC 2020)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Calcium Signaling in Mobile Molecular Communication Networks2019

    • Author(s)
      P. He, T. Nakano, D. Wu, B. Yang, H. Liu, and X. Han
    • Organizer
      IEEE Global Communications Conference (IEEE GLOBECOM 2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Data-driven Simulation of Epidemic Information Dissemination in Mobile Molecular Communication2019

    • Author(s)
      S. Ishiyama, T. Nakano, Y. Okaie, T. Hara and K. Harumoto
    • Organizer
      ACM International Conference on Nanoscale Computing and Communication (ACM NanoCom 2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Modeling the Stochastic Behavior of Kinesin-Coated Beads2019

    • Author(s)
      T. Suda and T. Nakano
    • Organizer
      IEEE International Conference on Communications (IEEE ICC 2019)
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Chemotaxis-based Multi-hop Molecular Nanonetworks for Target Detection2019

    • Author(s)
      L. Yang, X. Ge, Q. Liu, K. Yang, Y. Chen and T. Nakano
    • Organizer
      IEEE/CIC ICCC 2019 Workshop on Molecular, Biological, and Multiscale Communications
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 分子通信と形態形成2018

    • Author(s)
      中野 賢
    • Organizer
      電子報通信学会 情報ネットワーク科学研究会
    • Related Report
      2018 Annual Research Report
    • Invited
  • [Presentation] Epidemic Information Dissemination in Mobile Molecular Communication Systems2018

    • Author(s)
      S. Ishiyama, T. Nakano, Y. Okaie, and T. Hara
    • Organizer
      IEEE Global Communications Conference (IEEE Globecom 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Bio-inspired Design and Implementation of Mobile Molecular Communication Systems at the Macroscale2018

    • Author(s)
      H. Zhai, L. Yang, T. Nakano, Q. Liu and K. Yang
    • Organizer
      EEE Global Communications Conference (IEEE Globecom 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Modeling and Simulations of Bio-nanomachines for Spatiotemporal Pattern Formation2018

    • Author(s)
      T. Nakano and T. Suda
    • Organizer
      5th ACM/IEEE International Conference on Nanoscale Computing and Communication (ACM/IEEE NanoCom 2018)
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Pattern Formation by Mobile Molecular Communication Systems2018

    • Author(s)
      T. Nakano
    • Organizer
      International Technical Conference on Circuits/Systems, Computers and Communications (ITC-CSCC 2018), Special session on Nano Communication Networks
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Impacts of SW-ARQ on the Latency and Reliability of Diffusive, In-sequence Molecular Communication2018

    • Author(s)
      K. Furuhashi, J. Mitzman, J. Suzuki, T. Nakano, Y. Okaie, and H. Fukuda
    • Organizer
      2018 International Workshop on Molecular, Biological and Multiscale Communications
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Communication-inspired Model of Epidemic Spreading and Mitigation2018

    • Author(s)
      Y. Chen, Y. Zhou, R. Murch, and T. Nakano
    • Organizer
      2018 International Workshop on Molecular, Biological and Multiscale Communications
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Molecular Communication as a Biological System2018

    • Author(s)
      T. Suda and T. Nakano
    • Organizer
      2018 International Workshop on Molecular, Biological and Multiscale Communications
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Decoding Dynamic Signals in Molecular Communication2017

    • Author(s)
      T. Nakano
    • Organizer
      2017 IEEE Information Theory Workshop
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Molecular Communication Networks: Applications to Targeted Drug Delivery2017

    • Author(s)
      T. Nakano
    • Organizer
      The 15th Canadian Workshop on Information Theory
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Mobile Molecular Communication Networks for Targeted Drug Delivery2017

    • Author(s)
      T. Nakano
    • Organizer
      The 2nd Workshop on Molecular Communications
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Remarks] 大阪大学データビリティフロンティア機構 分子通信工学研究室

    • URL

      http://www.fbs.osaka-u.ac.jp/labs/tadashi_nakano/index.html

    • Related Report
      2019 Annual Research Report
  • [Remarks] がん細胞が血管網に似た構造を造る仕組みを解明

    • URL

      http://resou.osaka-u.ac.jp/ja/research/2020/20200312_1

    • Related Report
      2019 Annual Research Report

URL: 

Published: 2017-04-28   Modified: 2023-01-30  

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