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Extracting candidates of compounds to be monitored for drinking water by unknown screening analysis using high resolution accurate mass spectrometer

Research Project

Project/Area Number 17H03330
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Civil and environmental engineering
Research InstitutionThe University of Tokyo

Principal Investigator

Futoshi Kurisu  東京大学, 大学院工学系研究科(工学部), 准教授 (30312979)

Co-Investigator(Kenkyū-buntansha) 春日 郁朗  東京大学, 大学院工学系研究科(工学部), 准教授 (20431794)
高梨 啓和  鹿児島大学, 理工学域工学系, 准教授 (40274740)
島崎 大  国立保健医療科学院, その他部局等, 上席主任研究官 (60322046)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥17,030,000 (Direct Cost: ¥13,100,000、Indirect Cost: ¥3,930,000)
Fiscal Year 2019: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2018: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Fiscal Year 2017: ¥5,720,000 (Direct Cost: ¥4,400,000、Indirect Cost: ¥1,320,000)
Keywords精密質量分析 / 水道 / 未規制物質 / 未知スクリーニング / ノンターゲット分析 / ノンターゲットスクリーニング
Outline of Final Research Achievements

We aimed to develop a method for extracting unregulated but important compounds to manage the water quality in river water and identifying them at the compound level. Using a technique to detect low-molecular organic compounds as much as possible using a high resolution and accurate mass spectrometer, we screened organic substances that remained in purified water and/or constantly detected in the river water from the compounds that were not considered to be of natural origin. As a result, we were able to detect the compounds that should be monitored in the future, including detergents and their presumed decomposition products.

Academic Significance and Societal Importance of the Research Achievements

有害性がよく知られている物質や、従来ひろく用いられてきた物質については、その危険性に応じて水質基準や監視方法が定められおり、水の安全性が担保されている。しかし一方で、常に新たな物質が開発され使用されて環境中に放出されていること、また環境中に放出された後に分解を経ることでより毒性の高い物質になるものの存在も知られている。本研究では、特に水道水質管理の手法として、有機物を可能な限り網羅的に検出測定する方法を適用し、未規制の化学物質を監視していく方法を提案した。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Annual Research Report
  • 2017 Annual Research Report
  • Research Products

    (9 results)

All 2020 2019 2018 2017

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results) Presentation (7 results) (of which Int'l Joint Research: 3 results)

  • [Journal Article] Molecular characteristics of dissolved organic matter transformed by O3 and O3/H2O2 treatments and the effects on formation of unknown disinfection by-products2019

    • Author(s)
      Phungsai, P., Kurisu, F., Kasuga, I. and Furumai, H.
    • Journal Title

      Water Research

      Volume: 159 Pages: 214-222

    • DOI

      10.1016/j.watres.2019.05.002

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Changes in Dissolved Organic Matter Composition and Disinfection Byproduct Precursors in Advanced Drinking Water Treatment Processes2018

    • Author(s)
      Phungsai Phanwatt、Kurisu Futoshi、Kasuga Ikuro、Furumai Hiroaki
    • Journal Title

      Environmental Science & Technology

      Volume: 52 Issue: 6 Pages: 3392-3401

    • DOI

      10.1021/acs.est.7b04765

    • Related Report
      2017 Annual Research Report
  • [Presentation] 非意図的な処理水再利用のある入間川における溶存有機物の精密質量分析計を用いた追跡2020

    • Author(s)
      石井淑大、栗栖太、春日郁朗、古米弘明
    • Organizer
      第54回日本水環境学会年会講演集
    • Related Report
      2019 Annual Research Report
  • [Presentation] Changes in Dissolved Organic Matter Profile and Disinfection Byproducts Precursors by Ozonation and Peroxone Treatments2019

    • Author(s)
      Phungsai, P., Kurisu, F., Kasuga, I. and Furumai, H. .
    • Organizer
      The 7th IWA Specialst Conference on Natural Organic Matter in Water
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Tracking the Fate of Dissolved Organic Matter from River Source Water to Finished Drinking Water2019

    • Author(s)
      Yoshihiro ISHII, Jun HATAKEYAMA, Futoshi KURISU, Ikuro KASUGA, Hiroaki FURUMAI
    • Organizer
      The 7th IWA Specialst Conference on Natural Organic Matter in Water
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 荒川支流入間川における未規制有機汚染物質の精密質量計を用いたノンターゲット分析.2019

    • Author(s)
      畠山準, 松原直也, 栗栖太, 春日郁朗, 古米弘明
    • Organizer
      第53回日本水環境学会年会講演集
    • Related Report
      2018 Annual Research Report
  • [Presentation] Molecular-level Assessment of Dissolved Organic Matter Removal by MIEX(R) in Drinking Water Treatment.2018

    • Author(s)
      PHUNGSAI, P., KURISU, F., KASUGA, I. and FURUMAI, H.
    • Organizer
      IWA World Water Congress
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 微生物再増殖に関わる生分解性有機物の分子組成の推定と高度浄水処理における動態評価2018

    • Author(s)
      鈴木美有、春日郁朗、栗栖太、古米弘明
    • Organizer
      第52回日本水環境学会年会講演集
    • Related Report
      2017 Annual Research Report
  • [Presentation] 国内の水道原水および水道水における硫酸塩の存在状況2017

    • Author(s)
      島﨑大,秋葉道宏
    • Organizer
      第62回日本透析医学会学術集会・総会
    • Related Report
      2017 Annual Research Report

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Published: 2017-04-28   Modified: 2021-02-19  

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