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Establishment of new infection control for home dental care environment as indicator of oral pathogenic bacteria

Research Project

Project/Area Number 17K12008
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Social dentistry
Research InstitutionThe University of Tokushima

Principal Investigator

WATANABE Akari  徳島大学, 大学院医歯薬学研究部(歯学域), 助教 (80585026)

Co-Investigator(Kenkyū-buntansha) 横田 憲治  岡山大学, 保健学研究科, 教授 (00243460)
苔口 進  岡山大学, 医歯薬学総合研究科, 准教授 (10144776)
松山 美和  徳島大学, 大学院医歯薬学研究部(歯学域), 教授 (30253462)
Project Period (FY) 2017-04-01 – 2020-03-31
Project Status Completed (Fiscal Year 2019)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2019: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2018: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2017: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords在宅歯科医療実施環境 / メチシリン耐性ブドウ球菌 / 病原細菌汚染状況 / 保菌状況調査 / ATP測定法 / 口腔衛生管理 / 地域在住高齢者 / 感染予防対策 / 手指爪衛生評価 / 口腔レンサ球菌 / 吸い飲み / 歯学 / 感染症 / 微生物 / 在宅歯科医療環境 / 感染制御
Outline of Final Research Achievements

The opportunities of home dental care for elderly in need of nursing care and immunocompromised patients have been increasing. The improvement and establishment of the infection control for home dental care under differing environment with dental clinic are present urgent issues. The purpose of this study was to investigate the pollution status of the environments during home dental care and the habitat of oral pathogenic bacteria in the elderly in need of nursing care at home. This study revealed the spread of the community-acquired methicillin-resistant staphylococci in their oral cavities. It is necessary to pay attention to their future trends. The ATP measurement values used for the survey of environmental cleanliness showed the positive correlation with the number of bacteria in oral cavity, which could be led to the oral hygiene state evaluation.

Academic Significance and Societal Importance of the Research Achievements

唾液には院内感染病因細菌や新型コロナウイルスも多量に含まれ、歯科治療や口腔ケアの際には患者からエアロゾル飛沫の暴露リスクが非常に高い。歯科医院と比べ感染対策が十分でない在宅歯科医療実施環境における危険性についても言及したことは時宜を得て社会的意義がある。特に感染リスクの高い高齢者を対象とした口腔衛生管理の感染予防対策にも繋がるATP測定法はエビデンスに基づく1つの有力な指標として学術的意義がある。

Report

(4 results)
  • 2019 Annual Research Report   Final Research Report ( PDF )
  • 2018 Research-status Report
  • 2017 Research-status Report
  • Research Products

    (24 results)

All 2020 2019 2018 2017 Other

All Journal Article (11 results) (of which Peer Reviewed: 11 results,  Open Access: 8 results) Presentation (12 results) (of which Int'l Joint Research: 7 results) Remarks (1 results)

  • [Journal Article] Risk of Gastric Cancer in the Second Decade of Follow-Up After Helicobacter Pylori Eradication2020

    • Author(s)
      Take S, Mizuno M, Ishiki K, Kusumoto C, Imada T, Hamada F, Yoshida T, Yokota K, Mitsuhashi T, Okada H.
    • Journal Title

      J Gastroenterol .

      Volume: 55 Issue: 3 Pages: 281-288

    • DOI

      10.1007/s00535-019-01639-w

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Correction To: Risk of Gastric Cancer in the Second Decade of Follow-Up After Helicobacter Pylori Eradication2020

    • Author(s)
      Take S, Mizuno M, Ishiki K, Kusumoto C, Imada T, Hamada F, Yoshida T, Yokota K, Mitsuhashi T, Okada H.
    • Journal Title

      J. Gastroenterol .

      Volume: 55 Issue: 3 Pages: 289-290

    • DOI

      10.1007/s00535-019-01654-x

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 吸い飲みの微生物汚染状況に関する実験的予備調査2019

    • Author(s)
      渡辺 朱理, 長岡 仁美, 中江 弘美, 吉岡 昌美, 横田 憲治, 松山 美和, 苔口 進
    • Journal Title

      醫學と生物學

      Volume: 159(4) Pages: 1-6

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 高齢脳血管疾患患者における摂食嚥下機能と開口力の関係2019

    • Author(s)
      中村 吉伸, 松山 美和, 大村 智也, 渡辺 朱理, 東田 武志
    • Journal Title

      日本老年医学会雑誌

      Volume: 56(3) Pages: 265-272

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Increase in antibiotic resistant Helicobacter pylori in a University Hospital in Japan2019

    • Author(s)
      Kageyama Chihiro、Sato Mayu、Sakae Hiroyuki、Obayashi Yuka、Kawahara Yoshiro、Mima Takehiko、Matsushita Osamu、Yokota Kenji、Mizuno Motowo、Okada Hiroyuki
    • Journal Title

      Infection and Drug Resistance

      Volume: 12 Pages: 597-602

    • DOI

      10.2147/idr.s196452

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] A survey of Lasioderma serricorne (Fabricius) in Japanese Dental Clinics2019

    • Author(s)
      Watanabe A, Takaku S, Yokota K, Hayashi S, Tamaki N, Kokeguchi S
    • Journal Title

      Biocontrol Science

      Volume: -

    • NAID

      130007664023

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] DEC205 mediates local and systemic immune responses to Helicobacter pylori2018

    • Author(s)
      Kita M, Yokota K, Kageyama C, Take S, Goto K, Kawahara Y, Matsushita O, Okada H
    • Journal Title

      Oncotarge

      Volume: 9(22) Issue: 22 Pages: 15828-15835

    • DOI

      10.18632/oncotarget.24574

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Association of host immunity with Helicobacter pylori infection in recurrent gastric cancer2018

    • Author(s)
      Sato M, Miura K, Kageyama C, Sakae H, Obayashi Y, Kawahara Y, Matsushita O, Yokota K, Okada H
    • Journal Title

      Infect Agent Cancer

      Volume: 14 Issue: 1 Pages: 4-4

    • DOI

      10.1186/s13027-019-0221-1

    • Related Report
      2018 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] 環境汚染菌の消毒剤および除菌洗浄剤含浸ワイプによる拭き取り除去効果2018

    • Author(s)
      横田 憲治, 渡邉 都貴子, 林 俊治, 渡辺 朱理, 苔口 進, 平井 義一, 松下 治
    • Journal Title

      日本防菌防黴学会誌

      Volume: 46 Pages: 3-8

    • NAID

      40021444078

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] Use of ATP Bioluminescence to Survey the Spread of Aerosol and Splatter during Dental Treatment2018

    • Author(s)
      Watanabe A, Tamaki N, Yokota K, Matsuyama M, Kokeguchi S
    • Journal Title

      Journal of Hospital Infection

      Volume: - Issue: 3 Pages: 303-305

    • DOI

      10.1016/j.jhin.2018.03.002

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Journal Article] 言語聴覚士による4種の嚥下スクリーニングテストの主観的評価2017

    • Author(s)
      松尾 貴央, 松山 美和, 渡辺 朱理, 中谷 謙, 前田 留美子
    • Journal Title

      言語聴覚研究

      Volume: 14 Pages: 40-46

    • Related Report
      2017 Research-status Report
    • Peer Reviewed
  • [Presentation] Microbial Contamination and Growth in Feeding Cups2019

    • Author(s)
      Akari Watanabe, Kenji Yokota, Naofumi Tamaki and Susumu Kokeguchi
    • Organizer
      4th Meeting of the International Association for Dental Research Asia Pacific Region 2019
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 歯科矯正装置に対する口腔清掃補助用具の清掃効果2019

    • Author(s)
      渡辺 朱理, 鶴田 真生, 苔口 進, 松山 美和
    • Organizer
      日本歯科衛生学会第14回学術大会
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 地域在住高齢者におけるメチシリン耐性ブドウ球菌の保菌状況調査2019

    • Author(s)
      渡辺 朱理, 横田 憲治, 林 俊治, 苔口 進
    • Organizer
      第34回日本環境感染学会総会・学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] 内視鏡洗浄機の細菌汚染調査2019

    • Author(s)
      平井 一行, 平井 義一, 渡辺 朱理, 横田 憲治
    • Organizer
      第34回日本環境感染学会総会・学術集会
    • Related Report
      2018 Research-status Report
  • [Presentation] Effects of Oral Cleaning and Mouthwash in the Hospitalized Elderly2018

    • Author(s)
      Akari Watanabe, Yokota Kenji, Naofumi Tamaki and Kokeguchi Susumu
    • Organizer
      96th General Session & Exhibition of the IADR IADR Pan European Regional Congress
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research
  • [Presentation] 吸い飲みにおける衛生学的検討2018

    • Author(s)
      渡辺 朱理, 長岡 仁美, 中江 弘美, 吉岡 昌美, 苔口 進, 松山 美和
    • Organizer
      日本歯科衛生学会第13回学術大会
    • Related Report
      2018 Research-status Report
  • [Presentation] 尿沈渣標本中に出現する顆粒状物質と尿路感染症細菌との関連について2018

    • Author(s)
      佐藤 妃映, 横田 憲治, 渡辺 朱理, 苔口 進, 衛藤 友美, 高阪 翔士
    • Organizer
      第33回日本環境感染学会総会・学術集会
    • Related Report
      2017 Research-status Report
  • [Presentation] Survey of Methicillin-Resistant Staphylococci From Hospital Environment in Japan2017

    • Author(s)
      Akari Watanabe, Naofumi Tamaki, Kenji Yokota, Miwa Matsuyama and Susumu Kokeguchi
    • Organizer
      International Union of Microbiological Societies(IUMS2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Campylobacter Jejuni/Coli Infection is Associated with Tafro Syndrome2017

    • Author(s)
      Chihiro Kageyama, Osamu Matsushita, Akari Watanabe, Yasuharu Sato and Kenji Yokota
    • Organizer
      International Union of Microbiological Societies(IUMS2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] The IL10 Response and T Helper2 Immunity are Important in Hericobacter Pylori-Associated Gastric Cancer2017

    • Author(s)
      Mayu Sato, Osamu Matsushita, Akari Watanabe, Kou Miura, Hiroyuki Okada and Kenji Yokota
    • Organizer
      International Union of Microbiological Societies(IUMS2017)
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] Survey of Dissemination of Aerosol and Splatter during Dental Treatments2017

    • Author(s)
      Akari Watanabe, Naofumi Tamaki, Kenji Yokota, Susumu Kokeguchi and Miwa Matsuyama
    • Organizer
      The4th ASEAN plus and TOKUSHIMA Joint International Conference on Challenging and Innovation in Oral Sciences
    • Related Report
      2017 Research-status Report
    • Int'l Joint Research
  • [Presentation] 歯科予防処置における飛散汚染状況調査ーATP測定法と細菌培養法からの検討ー2017

    • Author(s)
      渡辺 朱理, 苔口 進, 横田 憲治, 松山 美和
    • Organizer
      日本歯科衛生学会第12回学術大会
    • Related Report
      2017 Research-status Report
  • [Remarks] 徳島大学教育研究者総覧

    • URL

      http://pub2.db.tokushima-u.ac.jp/ERD/person/261377/work-ja.html

    • Related Report
      2019 Annual Research Report 2018 Research-status Report 2017 Research-status Report

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Published: 2017-04-28   Modified: 2021-02-19  

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