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Creative and Highly Efficient Synthesis of Biologically Functional Molecules and Its Application in Drug Development Study

Research Project

Project/Area Number 18209002
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section一般
Research Field Chemical pharmacy
Research InstitutionOsaka University

Principal Investigator

KITA Yasuyuki  Osaka University, 薬学部, 教授 (00028862)

Co-Investigator(Kenkyū-buntansha) FUJIOKA Hiromichi  大阪大学, 薬学研究科, 教授 (10173410)
DOHI Toshifumi  立命館大学, 薬学部, 助教 (50423116)
Project Period (FY) 2006 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥42,900,000 (Direct Cost: ¥33,000,000、Indirect Cost: ¥9,900,000)
Fiscal Year 2008: ¥12,350,000 (Direct Cost: ¥9,500,000、Indirect Cost: ¥2,850,000)
Fiscal Year 2007: ¥14,300,000 (Direct Cost: ¥11,000,000、Indirect Cost: ¥3,300,000)
Fiscal Year 2006: ¥16,250,000 (Direct Cost: ¥12,500,000、Indirect Cost: ¥3,750,000)
Keywords有機化学 / 合成化学 / 生体関連物質 / 生薬・天然物化学 / 有機反応学 / ヘテロ環化学 / 不斉合成 / 生物活性物質 / 立体選択的合成 / 環境対応 / 創薬化学 / 全合成 / 有機ヨウ素 / アルカロイド / 有機触媒 / 触媒 / リサイクル
Research Abstract

Creative and environmentally friendly synthetic methods have been established for the purpose of obtaining a series of natural products which have complicated and high dimensional structures showing interesting biological activities but occurring only in small amounts in nature, living body-functioned molecules, and for construction of their key structures. Based on these groups of new compounds synthesized, a drug development study toward a creation of novel medicinal targets that show new mechanisms has been advanced in collaboration with other research groups and institutes having original drug evaluation systems.

Report

(5 results)
  • 2009 Final Research Report ( PDF )
  • 2008 Annual Research Report   Self-evaluation Report ( PDF )
  • 2007 Annual Research Report
  • 2006 Annual Research Report
  • Research Products

    (194 results)

All 2009 2008 2007 2006 Other

All Journal Article (85 results) (of which Peer Reviewed: 43 results) Presentation (88 results) Book (16 results) Patent(Industrial Property Rights) (5 results)

  • [Journal Article] Metal-free oxidative cross-coupling of unfunctionalized aromatic compounds2009

    • Author(s)
      Y. Kita, T. Dohi et, al.
    • Journal Title

      J. Am. Chem. Soc. 131

      Pages: 1668-1669

    • Related Report
      2009 Final Research Report
  • [Journal Article] The first total synthesis of prianosin B2009

    • Author(s)
      Y. Kita et, al.
    • Journal Title

      Tetrahedron 65

      Pages: 1059-1062

    • Related Report
      2009 Final Research Report
  • [Journal Article] Metal-free oxidative cross-coupling of unfunctionalized aromatic compounds2009

    • Author(s)
      Y. Kita, A. Morimoto, M. Ito, C. Ogawa, A. Goto, T. Dohi
    • Journal Title

      Journal of the American Chemical Society 131

      Pages: 1668-1669

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] The first total synthesis of prianosin B2009

    • Author(s)
      KITA, Yasuyuki, et al.
    • Journal Title

      Tetrahedron 65

      Pages: 1059-1062

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Tandem β-enamino ester formation and cyclization with o-alkynylanilines catalyzed by InBr_3 : efficient synthesis of β-(N-indolyl)-α, β-unsaturated esters2009

    • Author(s)
      KITA, Yasuyuki, FUJIOKA, Hiromichi, et al.
    • Journal Title

      J.Org.Chem. 74

      Pages: 1418-1421

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metal-free oxidative cross-coupling of unfunctionalized aromatic compounds2009

    • Author(s)
      KITA, Yasuyuki, DOHI, Toshifumi, et al.
    • Journal Title

      J.Am.Chem.Soc. 131

      Pages: 1668-1669

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mild and efficient deprotection of acetal-type protecting groups of hydroxyl functions by triethylsilyl triflate-2,4,6-collidine combination2009

    • Author(s)
      FUJIOKA, Hiromichi, KITA, Yasuyuki, et al.
    • Journal Title

      Heterocycles 77

      Pages: 1089-1103

    • NAID

      40016454347

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A highly efficient macrolactonization method via ethoxyvinyl ester2009

    • Author(s)
      KITA, Yasuyuki, et al.
    • Journal Title

      Chem.Eur.J. 15

      Pages: 3526-3537

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hypervalent iodine reagents as a new entrance to organocatalysts2009

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki
    • Journal Title

      Chem.Commun.

      Pages: 2073-2085

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Hypervalent iodine/Et_4N^+Br combination in water for green and racemization-free aqueous oxidation of alcohols2009

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki, et al.
    • Journal Title

      Tetrahedron Lett. 50

      Pages: 3227-3229

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clean and direct synthesis of α,α'-bithiophenes and bipyrroles by metalfree oxidative coupling using recyclable hypervalent iodine(III)reagents2009

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki, et al.
    • Journal Title

      Chem.Pharm.Bull. 57

      Pages: 710-713

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organoiodine-catalyzed oxidative spirocyclization of phenols using peracetic acid as green and economical terminal oxidant2009

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki, et al.
    • Journal Title

      Aust.J.Chem. 62

      Pages: 648-652

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organic chemistry using weakly electrophilic salts : the reaction with nitrogen nucleophiles2009

    • Author(s)
      FUJIOKA, Hiromichi, et al.
    • Journal Title

      Heterocycles 77

      Pages: 1113-1120

    • NAID

      40016543135

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Stereocontrol between remote atom centers using chiral acetals and its application to asymmetric syntheses of natural products2009

    • Author(s)
      FUJIOKA, Hiromichi, KITA Yasuyuki
    • Journal Title

      有機合成化学協会誌 67

      Pages: 606-617

    • NAID

      10024969346

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of biaryl compounds through there-component assembly: ambident effect of the tert-butyldimethylsilyl group for regioselective Diels-Alder and Hiyama coupling reactions2008

    • Author(s)
      S. Akai, Y. Kita et, al.
    • Journal Title

      Angew. Chem., Int. Ed. 47

      Pages: 7673-7676

    • Related Report
      2009 Final Research Report
  • [Journal Article] A chiral hypervalent iodine(III) reagent for enantioselective dearomatization of phenols2008

    • Author(s)
      T. Dohi, Y. Kita et, al.
    • Journal Title

      Angew. Chem., Int. Ed. 47

      Pages: 3787-3790

    • Related Report
      2009 Final Research Report
  • [Journal Article] Oxidative cross-coupling of arenes induced by single-electron transfer leading to biaryls by use of organoiodine(III) oxidants2008

    • Author(s)
      T. Dohi, Y. Kita et, al.
    • Journal Title

      Angew. Chem., Int. Ed. 47

      Pages: 1301-1304

    • Related Report
      2009 Final Research Report
  • [Journal Article] Facile formation of tetrahydrofurans with multiple chiral centers using double iodoetherification of σ-symmetric diene acetals : short asymmetric total synthesis of rubrenolide and rubrynolide2008

    • Author(s)
      FUJIOKA, Hiromichi, KITA, Yasuyuki, et al.
    • Journal Title

      Tetrahedron 64

      Pages: 4233-4245

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A chiral hypervalent iodine(III)reagent for enantioselective dearomatization of phenols2008

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki, et al.
    • Journal Title

      Angew.Chem.Int.Ed. 47

      Pages: 3787-3790

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A new H_2O_2/acid anhydride system for the iodoarene-catalyzed C-C bond-forming reactions of phenols2008

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki, et al.
    • Journal Title

      Org.Lett. 10

      Pages: 3559-3562

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clean and efficient benzylic C-H oxidation in water using a hypervalentiodine reagent : activation of polymeric iodosobenzene with KBr in the presence of Montmorillonite-K102008

    • Author(s)
      DOHI, Toshifumi, KITA, Yasuyuki, et al.
    • Journal Title

      J.Org.Chem. 73

      Pages: 7365-7368

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative decarboxylative synthesis of 2-H-imidazolines from glyoxylicacid and 1,2-diamines2008

    • Author(s)
      FUJIOKA, Hiromichi, KITA, Yasuyuki, et al.
    • Journal Title

      Chem.Commun.

      Pages: 4498-4500

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of biaryl compounds through three-component assembly : ambidentate effect of the tert-butyldimethylsilyl group for regioselective Diels-Alder and Hiyama coupling reactions2008

    • Author(s)
      KITA, Yasuyuki, et al.
    • Journal Title

      Angew.Chem.Int.Ed. 47

      Pages: 7673-7676

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] One-pot three-component reaction providing 1,5-benzodiazepine derivatives2008

    • Author(s)
      KITA, Yasuyuki, FUJIOKA, Hiromichi, et al.
    • Journal Title

      Tetrahedron 64

      Pages: 11034-11040

    • Related Report
      2008 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative Cross-Coupling of Arenes Induced by Single-Electron Transfer Leading to Biarvls by Use of Organoiodine (III) Oxidants2008

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 1301-1304

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Facile Formation of Tetrahydrofurans with Multiple Chiral Centers Using Double Iodoetherification of o-Symmetric Diene Acetals: Short Asymmetric Total Synthesis of Rubrenolide and Rubrynolide2008

    • Author(s)
      Fujioka Hiromichi; Kita Yasuyuki, et al.
    • Journal Title

      Tetrahedron 64

      Pages: 4233-4245

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A New Chiral Hypervalent Iodine (III) Reagent for Enantioselective Dearomatization of Phenols2008

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 3787-3790

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A New H_20_2/Acid Anhydride System for the Iodoarene-Catalyzed C-C Bond-Forming Reactions of Phenols2008

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Org. Lett. 10

      Pages: 3559-3562

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clean and Efficient Benzylic C-H Oxidation in Water Using a Hypervalent Iodine Reagent: Activation of Polymeric lodosobenzene with KBr in the Presence of Montmorillonite-K102008

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      J. Org. Chem. 73

      Pages: 7365-7368

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oxidative Decarboxylative Synthesis of 2-H-Imidazolines from Glyoxylic Acid and 1, 2-Diamines2008

    • Author(s)
      Fujioka, Hiromichi, Kita, Yasuyuki, et al.
    • Journal Title

      Chem. Commun.

      Pages: 4498-4500

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of Biaryl Compounds Through Three-Component Assembly: Ambidentate Effect of the tert-Butyldimethylsilyl Group for Regioselective Diels-Alder and Hiyama Coupling Reactions2008

    • Author(s)
      Kita, Yasuyuki, et al.
    • Journal Title

      Angew. Chem. Int. Ed. 47

      Pages: 7673-7676

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] One-Pot Three-Component Reaction Providing 1, 5-Benzodiazepine Derivatives2008

    • Author(s)
      Kita, Yasuyuki, Fujioka, Hiromichi, et al.
    • Journal Title

      Tetrahedron 64

      Pages: 11034-11040

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] First hypervalent iodine(III)-catalyzed C-N bond forming reaction: catalytic spirocyclization of amides to N-fused spirolactams2007

    • Author(s)
      T. Dohi, Y. Kita et, al.
    • Journal Title

      Chem. Commun.

      Pages: 1224-1226

    • Related Report
      2009 Final Research Report
  • [Journal Article] Synthesis of N-functionalized oleamide derivatives2007

    • Author(s)
      Y. Kita et, al
    • Journal Title

      Tetrahedron 63

      Pages: 3754-3761

    • Related Report
      2009 Final Research Report
  • [Journal Article] Enantioselective constructions of quaternary carbons and their application to the total syntheses of fredericamycin A and discorhabdin A2007

    • Author(s)
      H. Fujioka, Y. Kita
    • Journal Title

      Pure. Appl. Chem. 79

      Pages: 701-713

    • Related Report
      2009 Final Research Report
  • [Journal Article] Efficient synthesis of lactols by a domino reaction of 2, 3-epoxy alcohols with a hypervalent iodine(III) reagent and its application to the synthesis of lactones and the asymmetric synthesis of (+)-tanikolide2007

    • Author(s)
      H. Fujioka, Y. Kita et, al.
    • Journal Title

      Chem.-Eur. J. 13

      Pages: 5238-5248

    • Related Report
      2009 Final Research Report
  • [Journal Article] Versatile direct dehydrative approach for diaryliodonium(III) salts in fluoroalcohol media2007

    • Author(s)
      T. Dohi, Y. Kita et, al.
    • Journal Title

      Chem. Commun.

      Pages: 4152-4154

    • Related Report
      2009 Final Research Report
  • [Journal Article] The first total synthesis of (±)-γ-rubromycin via double aromatic Pummerer-type reactions2007

    • Author(s)
      S. Akai, T. Dohi, Y. Kita et, al.
    • Journal Title

      Angew. Chem., Int. Ed. 46

      Pages: 7458-7561

    • Related Report
      2009 Final Research Report
  • [Journal Article] Oleamide derivative suppress both tumor growth and spontaneous metastasis by inhibiting Connexin 262007

    • Author(s)
      Y. Ohba, Y. Kita, H. Nojima et, al.
    • Journal Title

      Int. J. Can. 121

      Pages: 47-54

    • Related Report
      2009 Final Research Report
  • [Journal Article] Concise asymmetric total synthesis of scyphostatin, a potent inhibitor of neutral sphingomyelinase2007

    • Author(s)
      H. Fujioka, Y. Kita et, al.
    • Journal Title

      Chem.-Eur. J. 13

      Pages: 10225-10238

    • Related Report
      2009 Final Research Report
  • [Journal Article] The first total synthesis of(±)-γ-rubromycin via double aromatic Pummerer-type reactions2007

    • Author(s)
      S. Akai, K. Kakiguchi,Y. Nakamura, I. Kuriwaki, T. Dohi,S. Harada, Y. Kita
    • Journal Title

      Angewandte Chemie, International Edition 46

      Pages: 7458-7561

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] Oleamide derivative suppress both tumor growth and spontaneous metastasis by inhibiting onnexin 262007

    • Author(s)
      Y. Ohba, Y. Kanao, N. Morita, E. Fujii, M. Horai, H. Hirose, D. Miura, A. Watari, M. Yutsudo, N. Yabuta, A. Ito, Y. Kita, H. Nojima
    • Journal Title

      International Journal of Cancer 121

      Pages: 47-54

    • Related Report
      2008 Self-evaluation Report
    • Peer Reviewed
  • [Journal Article] First Hypervalent Iodine (III)-Catalyzed C-N Bond Forming Reaction: Catalytic Spirocyclizatoin of Amides to N-Fused Spirolactams2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Chem. Commun.

      Pages: 1224-1226

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New Three-Component Reaction: Novel Formation of a Seven-Membered Ring by the Unexpected Reaction at the γ-Position of the β-Keto Ester2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et al.
    • Journal Title

      Org. Lett. 9

      Pages: 1687-1690

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Synthesis of N-Functionalized Oleamide Derivatives2007

    • Author(s)
      Kita, Yasuyuki, et al.
    • Journal Title

      Tetrahedron 63

      Pages: 3754-3761

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Enantioselective Constructions of Quaternary Carbons and Their Application to the Total Syntheses of Fredericamycin A and Discorhabdin A2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki
    • Journal Title

      Pure Appl. Chem. 79

      Pages: 701-713

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Nucleophilic Attack of Intramolecular Hydroxyl Groups on Electron-Rich Aromatics Using Hypervalent Iodine (III) Oxidation2007

    • Author(s)
      Kita, Yasuyuki, et al.
    • Journal Title

      Tetrahedron 63

      Pages: 4052-4060

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Efficient Synthesis of Lactols by a Domino Reaction of 2, 3-Epoxy Alcohols with a Hypervalent Iodine (III) Reagent and Its Application to the Synthesis of Lactones and the Asymmetric Synthesis of (+)-Tanikolide2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et al.
    • Journal Title

      Chem. Eur. J. 13

      Pages: 5238-5248

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regioselective Bipyrrole Coupling of Pyrroles and 3-Substituted Pyrroles Using Phenyliodine (III) Bis (trifluoroacetate)2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Synthesis

      Pages: 2913-2919

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct Lactone Formation by Using Hypervalent Iodine (III) Reagents with KBr via Selective C-H Abstraction Protocol2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Org. Lett. 9

      Pages: 3129-3132

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Versatile Direct Dehydrative Approach for Diaryliodonium (III) Salts in Fluoroalcohol Media2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et al.
    • Journal Title

      Chem. Commun.

      Pages: 4152-4154

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Total Synthesis of (±)-γ-Rubromycin on the Basis of Two Aromatic Pummerer-Type Reactions2007

    • Author(s)
      Kita, Yasuyuki; Dohi, Toshifumi, et al.
    • Journal Title

      Angew. Chem. Int. Ed. 46

      Pages: 7458-7461

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Organic Chemistry Using Weakly Electrophilic Salts: Efficient Formation of O, O-, O, S- and N, O-Mixed Acetals2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et al.
    • Journal Title

      J. Org. Chem. 72

      Pages: 7898-7902

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Oleamide Derivatives are Prototypical Anti-Metastasis Drugs that Act by Inhibiting Connexin 262007

    • Author(s)
      Kita, Yasuyuki, et al.
    • Journal Title

      Curr. Drug Safe. 2

      Pages: 204-211

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Concise Total Synthesis of (-)-Spongotine A2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et al.
    • Journal Title

      J. Org. Chem. 72

      Pages: 8947-8949

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] New Perspective for Natural Products Synthesis: Concise Synthesis of (+)-Sch 642305 by Chiral Auxiliary Multiuse Methodology2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et al.
    • Journal Title

      Org. Lett. 9

      Pages: 5605-5608

    • Related Report
      2007 Annual Research Report
    • Peer Reviewed
  • [Journal Article] リパーゼが触媒する不斉合成反応の新展開2007

    • Author(s)
      Kita, Yasuyuki, et al.
    • Journal Title

      有機合成化学協会誌 65

      Pages: 772-782

    • NAID

      10019753464

    • Related Report
      2007 Annual Research Report
  • [Journal Article] Direct Cyanation of Heteroaromatic Compounds Mediated by Hypervalent Iodine (III) Reagents; In Situ Generation of PhI (III)-CN Species and Their Cyano Transfer2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      J. Org. Chem. 72・1

      Pages: 109-116

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Cerium Ammonium Nitrate (CAN) for Mild and Efficient Removal Reagent of Hydroxyethyl Units2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Tetrahedron 63・3

      Pages: 625-637

    • Related Report
      2006 Annual Research Report
  • [Journal Article] One-Pot Synthesis of Imidazolines from Aldehydes: Detailed Study about Solvents and Substrates2007

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Tetrahedron 63・3

      Pages: 638-643

    • Related Report
      2006 Annual Research Report
  • [Journal Article] First Hypervalent Iodine (III)-Catalyzed C-N Bond Forming Reaction: Catalytic Spirocyclization of Amides2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      Chem. Commun. 12

      Pages: 1224-1226

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Oleamide Derivatives Suppress the Spontaneous Metastasis by Inhibiting Connexin 262007

    • Author(s)
      Kita, Yasuyuki, et. al.
    • Journal Title

      Int. J. Cancer 121・7

      Pages: 47-54

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Enantioselective Constructions of Quaternary Carbonds and Their Application to the Asymmetric Total Synthesis of Fredericamycin A and Discorhabdin A2007

    • Author(s)
      Kita, Yasuyuki Fujioka, Hiromichi
    • Journal Title

      Pure. Appl. Chem. 79・4

      Pages: 35-76

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Alkylation of Oxacyclic Ethers with TESOTf-2, 4, 6-Collidine-Gilman Reagent Combination2007

    • Author(s)
      Fujioka; Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Heterocycles 72

      Pages: 529-540

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Reaction of THP-ethers with TESOTf-2, 4, 6-Collidine Combination2007

    • Author(s)
      Fujioka; Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Adv. Synth. Catal. 349・4

      Pages: 636-646

    • Related Report
      2006 Annual Research Report
  • [Journal Article] New Three-Component Reaction: Novel Formation of a Seven-Membered Ring by the Unexpected Reaction2007

    • Author(s)
      Fujioka; Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Org. Lett. 9・9

      Pages: 1687-1690

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Direct Lactone Formation by Using Hypervalent Iodine(III) Reagents with KBr via Selective C-H Abstraction Protocol2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      Org. Lett. 9・16

      Pages: 3129-3132

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Total Synthesis of (±)-γ-Rubromycin on the Basis of Two Aromatic Pummerer-Type Reactions2007

    • Author(s)
      Kita, Yasuyuki, et. al.
    • Journal Title

      Angew. Chem. Int. Ed. (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Versatile Direct Dehydrative Approach for Diaryliodonium(III) Salts in Fluoroalcohol Media2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      Chem. Commun. (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Regioselective Bipyrrole Coupling of Pyrroles and 3-Substituted Pyrroles Using Phenyliodine(III) Bis (trifluoroacetate)2007

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      Synthesis (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Organic Chemistry Using Weakly Electrophilic Salts: Efficient Formation of O, O-Mixed, O, S-and N, O-Acetals2007

    • Author(s)
      Fujioka; Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      J. Org. Chem. (In press)

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A dynamic kinetic resolution of ally alcohols by the combined use of lipases and [VO(OSiPh3)3]2006

    • Author(s)
      S. Akai, Y. Kita et, al.
    • Journal Title

      Angew. Chem., Int. Ed. 45

      Pages: 2592-2595

    • Related Report
      2009 Final Research Report
  • [Journal Article] Direct synthesis of bipyrroles using phenyliodine(III) bis(trifluoroacetate) with bromotrimethylsilane2006

    • Author(s)
      T. Dohi, Y. Kita et, al.
    • Journal Title

      Org. Lett. 8

      Pages: 2007-2010

    • Related Report
      2009 Final Research Report
  • [Journal Article] Reaction of the acetals with TESOTf-base combination2006

    • Author(s)
      H. Fujioka, Y. Kita et, al.
    • Journal Title

      J. Am. Chem. Soc. 128

      Pages: 5930-5938

    • Related Report
      2009 Final Research Report
  • [Journal Article] The efficient direct synthesis of N, O-acetal compounds as key intermediates of discorhabdin A2006

    • Author(s)
      Y. Kita et, al.
    • Journal Title

      Chem.-Eur. J. 12

      Pages: 4893-4899

    • Related Report
      2009 Final Research Report
  • [Journal Article] Reaction of the Acetals with TESOTf-Base Combination2006

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      J. Am. Chem. Soc. 128・17

      Pages: 5930-5938

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Direct Synthesis of Bipyrroles Using Phenyliodine Bis (trifluoroacetate) with Bromotrimethylsilane2006

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      Org. Lett. 8・10

      Pages: 2007-2010

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A Dynamic Kinetic Resolution of Allyl Alcohols by the Combined Use of Lipases and [VO (OSiPh_3)_3]2006

    • Author(s)
      Kita, Yasuyuki, et. al.
    • Journal Title

      Angew. Chem. Int. Ed. 45・16

      Pages: 2592-2595

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Lewis Acid-Promoted Rearrangement of 2,3-Epoxy Alcohol Derivatives2006

    • Author(s)
      Kita, Yasuyuki; Fujioka, Hiromichi, et. al.
    • Journal Title

      J. Org. Chem. 71・14

      Pages: 5191-5197

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Development of environmentally benign oxidations using hypervalent iodine (III) reagents2006

    • Author(s)
      Dohi, Toshifumi
    • Journal Title

      Yakugaku Zasshi 126・9

      Pages: 757-766

    • NAID

      110006154986

    • Related Report
      2006 Annual Research Report
  • [Journal Article] The Efficient Direct Synthesis of N,O-Acetal Compounds as Key Intermediates of Discorhabdin A2006

    • Author(s)
      Kita, Yasuyuki, et. al.
    • Journal Title

      Chem. Eur. J. 12・18

      Pages: 4893-4899

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Highly Chemoselective Alkylation of Acetals Using TESOTf-2,4,6-Collidine-Gilman Reagent Combination2006

    • Author(s)
      Fujioka, Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Synlett 18

      Pages: 3077-3080

    • Related Report
      2006 Annual Research Report
  • [Journal Article] A Facile and Clean Direct Cyanation Using a Recyclable Hypervalent Iodine (III) Reagent2006

    • Author(s)
      Dohi, Toshifumi; Kita, Yasuyuki, et. al.
    • Journal Title

      Chem. Pharm. Bull. 54・12

      Pages: 1608-1610

    • Related Report
      2006 Annual Research Report
  • [Journal Article] リパーゼが触媒する不斉合成反応の新展開

    • Author(s)
      Kita, Yasuyuki, et. al.
    • Journal Title

      有機合成化学協会誌 (In press)

    • NAID

      10019753464

    • Related Report
      2006 Annual Research Report
  • [Journal Article] Concise Asymmetric Total Synthesis of Scyphostatin, a Potent Inhibitor of Neutral Sphingomyelinase

    • Author(s)
      Fujioka; Hiromichi; Kita, Yasuyuki, et. al.
    • Journal Title

      Chem. Eur. J. (In press)

    • Related Report
      2006 Annual Research Report
  • [Presentation] 光学活性rubromycin類の全合成研究2009

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-28
    • Related Report
      2009 Final Research Report
  • [Presentation] エンアセトナイド類の分子内ハロエーテル化反応を用いた光学活性環状エーテル骨格合成法の開発研究2009

    • Author(s)
      藤岡弘道, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超原子価ヨウ素反応剤とベンジル位三級シクロアルカノール類との反応2009

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] 光学活性 rubromycin 類の全合成研究2009

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-28
    • Related Report
      2008 Annual Research Report
  • [Presentation] レアメタル代替を目的とする新規ヨウ素反応剤を用いる合成法の開発(平成21年度日本薬学会奨励賞受賞講演)2009

    • Author(s)
      土肥寿文
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 光学活性ジエンアセタール類の分子内ハロエーテル化反応を利用する不斉誘導法の開発とその応用2009

    • Author(s)
      藤岡弘道
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都
    • Year and Date
      2009-03-26
    • Related Report
      2009 Final Research Report
  • [Presentation] 有機ヨウ素(III)を用いるチオフェン類の高H-T選択的二量化及びクロスカップリング反応2009

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] 新規スピロビフルオレン型ヨウ素(III)反応剤の合成2009

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヘテロ芳香族ヨードニウム塩へのアレーン類の新規置換反応2009

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] I(III)-Br 結合を有するヨウ素反応剤を用いた新規アミド化および求核種導入反応2009

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] アミナールの酸化によるイミダゾリン合成法のグリオキサル酸誘導体への応用2009

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都(京都国際会館)
    • Year and Date
      2009-03-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Organic synthesis using environmentally benign hypervalent iodine reagents: synthesis of biologically important natural products2008

    • Author(s)
      北泰行
    • Organizer
      The 23rd Royal Australian Chemical Institute Organic Chemistry Devision Conference (23 RACIOC)
    • Place of Presentation
      Hobart Tasmania (Australia)
    • Year and Date
      2008-12-07
    • Related Report
      2009 Final Research Report
  • [Presentation] Organic Synthesis Using Environmentally Benign Hypervalent Iodine Reagents : Synthesis of Biologically Important Natural Products2008

    • Author(s)
      北泰行
    • Organizer
      The 23rd Royal Australian Chemical Institute Organic Chemistry Division Conference(23 RACIOC)
    • Place of Presentation
      Hobart Tasmania(Australia)
    • Year and Date
      2008-12-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 抗腫瘍活性化合物discorhabdin類の生物活性と構造活性相関2008

    • Author(s)
      北泰行, 藤岡弘道, 他
    • Organizer
      第27回メディシナルケミストリーシンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2008-11-27
    • Related Report
      2009 Final Research Report
  • [Presentation] エナミノエステルを経るo-アルキニルアニリン類の環化反応による新規インドール合成法2008

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      第27回メディシナルケミストリーシンポジウム
    • Place of Presentation
      大阪(メルパルク大阪)
    • Year and Date
      2008-11-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] 抗腫瘍活性化合物 discorhabdin 類の生物活性と構造活性相関2008

    • Author(s)
      北泰行, 藤岡弘道, 他
    • Organizer
      第27回メディシナルケミストリーシンポジウム
    • Place of Presentation
      大阪(メルパルク大阪)
    • Year and Date
      2008-11-27
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超原子価ヨウ素反応剤を用いるヘテロ芳香族化合物の酸化的ビアリールカップリング反応2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第38回複素環化学討論会
    • Place of Presentation
      広島(広島県民文化センターふくやま)
    • Year and Date
      2008-11-23
    • Related Report
      2008 Annual Research Report
  • [Presentation] 光学活性スピロケタール類構築法の開発研究2008

    • Author(s)
      藤岡弘道, 他
    • Organizer
      第28回有機合成若手セミナー
    • Place of Presentation
      大阪(大阪大学)
    • Year and Date
      2008-11-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 超原子価ヨウ素反応剤を用いたスピロラクトン骨格の合成研究2008

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      第28回有機合成若手セミナー
    • Place of Presentation
      大阪(大阪大学)
    • Year and Date
      2008-11-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 新規ジエノン-フェノールタイプ転位反応を用いたチオエーテル類の簡便合成法の開発2008

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      第28回有機合成若手セミナー
    • Place of Presentation
      大阪(大阪大学)
    • Year and Date
      2008-11-12
    • Related Report
      2008 Annual Research Report
  • [Presentation] 新規キラルヨウ素(III)反応剤の設計とフェノール類の不斉酸化2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第94回有機合成シンポジウム
    • Place of Presentation
      東京(早稲田大学)
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヨウ素反応剤を用いるベンジル位の直接的官能基化法の開発2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第94回有機合成シンポジウム
    • Place of Presentation
      東京(早稲田大学)
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 置換チオフェン類の酸化的二量化反応:位置選択性の高度制御と反応剤のリサイクル2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第11回ヨウ素学会シンポジウム
    • Place of Presentation
      千葉(千葉大学)
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 活性有機ヨウ素(III)種を触媒とするフェノール類の酸化的C-C結合形成反応2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第11回ヨウ素学会シンポジウム
    • Place of Presentation
      千葉(千葉大学)
    • Year and Date
      2008-11-07
    • Related Report
      2008 Annual Research Report
  • [Presentation] 官能基化を必要としない新規酸化的ビアリールカップリング反応の開発2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第34回反応と合成の進歩シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2008-11-05
    • Related Report
      2009 Final Research Report
  • [Presentation] 官能基化を必要としない新規酸化的ビアリールカップリング反応の開発2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第34回反応と合成の進歩シンポジウム
    • Place of Presentation
      京都(京都テルサ)
    • Year and Date
      2008-11-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] アセタール型保護基の高官能基選択的脱保護法の開発2008

    • Author(s)
      藤岡弘道, 他
    • Organizer
      第34回反応と合成の進歩シンポジウム
    • Place of Presentation
      京都(京都テルサ)
    • Year and Date
      2008-11-05
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヨードアレーンを触媒とする酸化的C-C結合形成反応: Amaryllidaceae alkaloid 合成への応用2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第58回日本薬学会近畿支部大会
    • Place of Presentation
      神戸(神戸薬科大学)
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] ヨウ素反応剤を用いたベンジル位水素活性化に基づく求核種導入反応2008

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      第58回日本薬学会近畿支部大会
    • Place of Presentation
      神戸(神戸薬科大学)
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] エナミノエステルを経由する2-アルキニルアニリンの環化反応―N-βカルボキシビニルインドールの合成-2008

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      第58回日本薬学会近畿支部大会
    • Place of Presentation
      神戸(神戸薬科大学)
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] 新規ジエノン・フェノールタイプ転位反応の開発2008

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      第58回日本薬学会近畿支部大会
    • Place of Presentation
      神戸(神戸薬科大学)
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] 分子内ハロエーテル化反応を用いた dioxaspiro 骨格合成法の開発研究2008

    • Author(s)
      藤岡弘道, 他
    • Organizer
      第58回日本薬学会近畿支部大会
    • Place of Presentation
      神戸(神戸薬科大学)
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] ジオール類の環状アセタール型保護基の新規脱保護法の開発2008

    • Author(s)
      藤岡弘道, 他
    • Organizer
      第58回日本薬学会近畿支部大会
    • Place of Presentation
      神戸(神戸薬科大学)
    • Year and Date
      2008-10-25
    • Related Report
      2008 Annual Research Report
  • [Presentation] 創薬を志向する有機合成2008

    • Author(s)
      北泰行
    • Organizer
      平成20年度前期(春季)有機合成化学協会講習会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-18
    • Related Report
      2009 Final Research Report
  • [Presentation] 創薬を指向する有機合成2008

    • Author(s)
      北泰行
    • Organizer
      平成20年度前期(春季)有機合成化学協会講習会
    • Place of Presentation
      東京(長井記念ホール)
    • Year and Date
      2008-06-18
    • Related Report
      2008 Annual Research Report
  • [Presentation] 創薬を指向する有機合成2008

    • Author(s)
      北泰行
    • Organizer
      平成20年度前期有機合成化学協会講習会
    • Place of Presentation
      東京
    • Year and Date
      2008-06-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] Recent progress in hypervalent iodine chemistry for environmentally benign oxidati on reactions2008

    • Author(s)
      北泰行
    • Organizer
      3rd International Conference on Advanced Organic Synthesis Directed toward the Ultimate Efficiency and Practicability
    • Place of Presentation
      大津
    • Year and Date
      2008-05-26
    • Related Report
      2009 Final Research Report
  • [Presentation] Recent Progress in Hypervalent Iodine Chemistry for Environmentally Benign Oxidation Reactions2008

    • Author(s)
      北泰行
    • Organizer
      3rd International Conference on Advanced Organic Synthesis Directed toward the Ultimate Efficiency and Practicability
    • Place of Presentation
      大津(大津ロイヤルホテル)
    • Year and Date
      2008-05-26
    • Related Report
      2008 Annual Research Report
  • [Presentation] Recent Progress in Hypervalent Iodine Chemistry for Environmentally Benign Oxidation Reactions2008

    • Author(s)
      北泰行
    • Organizer
      3rd International Conference on Advanced Organic Synthesis Directed toward the Ultimate Efficiency and Practicability
    • Place of Presentation
      大津
    • Year and Date
      2008-05-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超原子価ヨウ素反応剤を用いる有機合成の新展開2008

    • Author(s)
      北泰行
    • Organizer
      第16回ファインケミカルズ研究会
    • Place of Presentation
      大津
    • Year and Date
      2008-05-15
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] 超原子価ヨウ素反応剤を用いる有機合成の新展開2008

    • Author(s)
      北泰行
    • Organizer
      第16回ファインケミカルズ研究会
    • Place of Presentation
      大阪(大阪市立工業研究所)
    • Year and Date
      2008-05-15
    • Related Report
      2008 Annual Research Report
  • [Presentation] 鎖状ジエンケタール類の分子内ハロエーテル化反応の開発2008

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 有機ヨウ素(III)反応剤による一電子酸化を鍵とするクロスビアリールカップリング反応の開発2008

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] アリルジメチルシリル置換ベンザインの位置選択的Diels-Alder反応を用いる多置換ナフタレン類の合成2008

    • Author(s)
      北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 有機ヨウ素酸化剤によるフェノール類の環境調和型分子変換2008

    • Author(s)
      土肥寿文
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超原子価ヨウ素(III)反応剤を用いるβ-アミノアルコール類の酸化的開裂反応の開発とその展開2008

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] 新規ワンポット3成分反応による1, 5-ベンゾジアゼピン骨格の構築2008

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] PIFA/TMSBrを用いたチオフェン類の高選択的カップリング反応2008

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] 活性有機ヨウ素(III)-プロミド中間体を利用するベンジル位C-H結合の酸化反応2008

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      日本薬学会第128年会
    • Place of Presentation
      横浜
    • Year and Date
      2008-03-26
    • Related Report
      2007 Annual Research Report
  • [Presentation] 創薬を志向する合成反応の開発と応用-グリーンケミストリーを考慮して-2008

    • Author(s)
      北泰行
    • Organizer
      日本薬学会東海支部特別講演会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-01-23
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] 創薬を志向する合成反応の開発と応用2008

    • Author(s)
      北泰行
    • Organizer
      有機合成化学協会新春講演会
    • Place of Presentation
      大阪
    • Year and Date
      2008-01-22
    • Related Report
      2009 Final Research Report 2007 Annual Research Report
  • [Presentation] 創薬を志向する合成反応の開発と応用-グウーンケミストリーを考慮して-2007

    • Author(s)
      北泰行
    • Organizer
      滋賀バイオ産業推進機構, 平成19年度第3回研究技術交流会
    • Place of Presentation
      草津
    • Year and Date
      2007-12-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] 反応を開発し、生物活性天然物の全合成完成を目指す2007

    • Author(s)
      北泰行
    • Organizer
      有機合成化学協会関東支部新潟シノポジウム
    • Place of Presentation
      新潟
    • Year and Date
      2007-12-01
    • Related Report
      2009 Final Research Report
  • [Presentation] 反応を開発し、生物活性天然物の全合成完成を目指す2007

    • Author(s)
      北泰行
    • Organizer
      有機合成化学協会関東支部新潟シンポジウム
    • Place of Presentation
      新潟
    • Year and Date
      2007-12-01
    • Related Report
      2007 Annual Research Report
  • [Presentation] N-SMase阻害活性を持つスキホスタチンの改良合成法の開発2007

    • Author(s)
      藤岡弘道, 北泰行, 他
    • Organizer
      第26回メディシナルケミストリーシンポジウム
    • Place of Presentation
      相模大野
    • Year and Date
      2007-11-28
    • Related Report
      2009 Final Research Report
  • [Presentation] イミダゾリン新規合成法を利用した海綿由来ビスインドールアルカロイドSpongotineAの全合成2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第26回 メディシナルケミストリーシンポジウム
    • Place of Presentation
      相模大野
    • Year and Date
      2007-11-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] N-SMase阻害活性を持つスキホスタチンの改良合成法の開発2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第26回 メディシナルケミストリーシンポジウム
    • Place of Presentation
      相模大野
    • Year and Date
      2007-11-28
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超原子価ヨウ素化学の新展開とグリーンケミストリー(第1回ヨウ素学会賞受賞講演)2007

    • Author(s)
      北泰行
    • Organizer
      第10回ヨウ素学会シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2007-11-17
    • Related Report
      2009 Final Research Report
  • [Presentation] 超原子価ヨウ素化学の新展開とグリーンケミストリー(ヨウ素学会賞受賞講演)2007

    • Author(s)
      北泰行
    • Organizer
      第10回 ヨウ素学会シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2007-11-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Development of Oxidative Lactone Forming Reaction at Benzyl Positions Using Hypervalent Iodine (III) Reagent2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      第10回 ヨウ素学会シンポジウム
    • Place of Presentation
      千葉
    • Year and Date
      2007-11-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] New Three-Component Reaction: Formation of Seven-Membered Ring by an Unexpected Reaction at the γ-Position of the β-Keto Esters2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      Green Substainable Biological and Chemical Processes
    • Place of Presentation
      大阪
    • Year and Date
      2007-11-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] Total Synthesis of Discorhabdin F, Prianosin B, and Related Oxa Analo gues by Dehydrogenation and Detosvlation Reaction2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      Green Substainable Biological and Chemical Processes
    • Place of Presentation
      大阪
    • Year and Date
      2007-11-16
    • Related Report
      2007 Annual Research Report
  • [Presentation] THPエーテルの高次利用を目指した研究2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第27回有機合成若手セミナー
    • Place of Presentation
      京都
    • Year and Date
      2007-11-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 水のみを副産物とする効果的ジアリールヨードニウム塩合成法の開発2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      第27回有機合成若手セミナー
    • Place of Presentation
      京都
    • Year and Date
      2007-11-15
    • Related Report
      2007 Annual Research Report
  • [Presentation] 新規オキソニウムイオン等価体への求核種導入反応2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第92回 有機合成化学協会シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-11-08
    • Related Report
      2007 Annual Research Report
  • [Presentation] 有機ヨウ素触媒を用いた酸化的スピロジエノン形成反応:溶媒効果と新触媒の開発2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      第33回 反応と合成の進歩シンポジウム
    • Place of Presentation
      長崎
    • Year and Date
      2007-11-06
    • Related Report
      2007 Annual Research Report
  • [Presentation] 抗腫瘍活性アルカロイドdiacorhabdin類の合成研究2007

    • Author(s)
      北泰行, 他
    • Organizer
      第33回反応と合成の進歩シンポジウム
    • Place of Presentation
      長崎
    • Year and Date
      2007-11-05
    • Related Report
      2009 Final Research Report
  • [Presentation] 抗腫瘍活性アルカロイドdiscorhabain類の合成研究2007

    • Author(s)
      北泰行, 他
    • Organizer
      第33回 反応と合成の進歩シンポジウム
    • Place of Presentation
      長崎
    • Year and Date
      2007-11-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] THPエーテル由来の活性カチオン種を利用する合成法の開発2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第57回日本薬学会近畿支部大会、総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-10-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] エトキシビニルエステルを介する高効率的マクロラクトン化反応の開発2007

    • Author(s)
      北泰行, 他
    • Organizer
      第57回日本薬学会近畿支部大会、総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-10-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] Spongotine Aの全合成研究2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第57回日本薬学会近畿支部大会、総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-10-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] フルオロアルコール溶媒を活用する新規なジアリールヨードニウム塩合成法2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      第57回日本薬学会近畿支部大会、総会
    • Place of Presentation
      大阪
    • Year and Date
      2007-10-27
    • Related Report
      2007 Annual Research Report
  • [Presentation] (±)-γ-Rubromycineの全合成2007

    • Author(s)
      北泰行, 他
    • Organizer
      第37回 複素環化学討論会
    • Place of Presentation
      長野
    • Year and Date
      2007-10-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] 芳香族アルデヒド、エチレンジアミン、βケトエステルを用いる新規な3成分反応2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      第37回 複素環化学討論会
    • Place of Presentation
      長野
    • Year and Date
      2007-10-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] 創薬を志向する新反応の開発と天然物合成への応用―グリーンケミストリーを志向してー2007

    • Author(s)
      北泰行
    • Organizer
      日本薬学会北陸支部特別講演会
    • Place of Presentation
      富山
    • Year and Date
      2007-10-05
    • Related Report
      2009 Final Research Report
  • [Presentation] 創薬を志向する新反応の開発と天然物合成への応用-グリーンケミストリーを志向して-2007

    • Author(s)
      北泰行
    • Organizer
      日本薬学会北陸支部特別講演会
    • Place of Presentation
      富山
    • Year and Date
      2007-10-05
    • Related Report
      2007 Annual Research Report
  • [Presentation] 超原子価ヨウ素化学の新展開2007

    • Author(s)
      北泰行
    • Organizer
      有機合成化学関西支部シンポジウム特別講演, 有機合成夏季セミナー「明日の有機化学」
    • Place of Presentation
      大阪
    • Year and Date
      2007-08-10
    • Related Report
      2009 Final Research Report
  • [Presentation] 超原子価ヨウ素化学の新展開2007

    • Author(s)
      北泰行
    • Organizer
      有機合成化関西支部シンポジウム特別講演, 有機合成夏期セミナー『明日の有機化学』
    • Place of Presentation
      大阪
    • Year and Date
      2007-08-10
    • Related Report
      2007 Annual Research Report
  • [Presentation] 有機ヨウ素触媒を用いるフェノール誘導体の酸化的スピロラクタム形成反応2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      日本プロセス化学会 サマーシンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2007-08-02
    • Related Report
      2007 Annual Research Report
  • [Presentation] Total synthesis ofγ-rubromycin2007

    • Author(s)
      北泰行
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      Sydney
    • Year and Date
      2007-07-18
    • Related Report
      2009 Final Research Report
  • [Presentation] Total Synthesis of γ-Rubromycin2007

    • Author(s)
      北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      オーストラリア、シドニー
    • Year and Date
      2007-07-18
    • Related Report
      2007 Annual Research Report
  • [Presentation] On the development of recyclable hypervalent iodine(III) reagents based on the tetrahedron structures2007

    • Author(s)
      土肥寿文, 北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      Sydney
    • Year and Date
      2007-07-17
    • Related Report
      2009 Final Research Report
  • [Presentation] Total synthesis of discorhabdin F, prianosin B, and related oxa analogues by dehydrogenation and detosylation reaction2007

    • Author(s)
      北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      Sydney
    • Year and Date
      2007-07-17
    • Related Report
      2009 Final Research Report
  • [Presentation] New Three-Component Reaction: Formation of Seven-Membered Ring by an Unexpected Reaction at the γ-Position of the β-Keto Esters2007

    • Author(s)
      藤岡弘道、北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      シドニー
    • Year and Date
      2007-07-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Total Synthesis of Discorhabdin F, Prianosin B, and Related Oxa Analo gues by Dehydrogenation and Detosylation Reaction2007

    • Author(s)
      北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      シドニー
    • Year and Date
      2007-07-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Catalytic Utilization of Hypervalent Iodine (III) Reagents: Spirodienone Forming Reaction in Fluoroalcohol Medium2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      オーストラリア、シドニー
    • Year and Date
      2007-07-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] On the Development of Recyclable Hypervalent Iodine (III) Reagents Bas ed on the Tetrahedral Structures2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      オーストラリア、シドニー
    • Year and Date
      2007-07-17
    • Related Report
      2007 Annual Research Report
  • [Presentation] Oxidative Biaryl Coupling of Electronic-Rich Aromatic and Heteroaroma tic Compounds Using Hypervalent Iodine (III) Reagents2007

    • Author(s)
      土肥寿文、北泰行, 他
    • Organizer
      21st International Congress for Heterocyclic Chemistry
    • Place of Presentation
      オーストラリア、シドニー
    • Year and Date
      2007-07-17
    • Related Report
      2007 Annual Research Report
  • [Book] 化学フロンティアシリーズ, 進化を続ける有機触媒2009

    • Author(s)
      土肥寿文, 北泰行(分担)
    • Total Pages
      10
    • Publisher
      化学同人
    • Related Report
      2009 Final Research Report
  • [Book] 医薬品原薬・中間体製造におけるスケールアップとトラブル対策(分担)2009

    • Author(s)
      藤岡弘道, 北泰行
    • Total Pages
      16
    • Publisher
      シーエムシー出版
    • Related Report
      2008 Annual Research Report
  • [Book] 化学フロンティアシリーズ, 進化を続ける有機触媒(分担)2009

    • Author(s)
      土肥寿文, 北泰行
    • Total Pages
      10
    • Publisher
      化学同人
    • Related Report
      2008 Annual Research Report
  • [Book] 化学2009

    • Author(s)
      藤岡弘道, 他
    • Total Pages
      2
    • Publisher
      化学同人
    • Related Report
      2008 Annual Research Report
  • [Book] Synthesis of anthracyclines and frederiamycin A via strong base-induced cycloaddition reaction of homophthalic anhydrides (Top. Curr. Chem.)2008

    • Author(s)
      北泰行, 藤岡弘道, 他(分担)
    • Total Pages
      21
    • Publisher
      Springer
    • Related Report
      2009 Final Research Report
  • [Book] In Top.Curr.Chem., Syntheses of anthracyclines and fredericamycin A viastrong base-induced cycloaddition reaction of homophthalic anhydrides2008

    • Author(s)
      KITA, Yasuyuki, FUJIOKA, Hiromichi
    • Total Pages
      21
    • Publisher
      Springer
    • Related Report
      2008 Annual Research Report
  • [Book] Topics in Current Chemistry, "Anthracyclines, Chemistry and Biology", Synthesis of Anthracyclines and Fredericamycin A Using Anionic Cycloaddition Reaction of Homophthalic Anhydrides. (分担)2008

    • Author(s)
      北泰行、藤岡弘道
    • Total Pages
      21
    • Publisher
      Springer
    • Related Report
      2007 Annual Research Report
  • [Book] 医薬品原薬, 中間体製造におけるスケールアップとトラブル対策, 最近の手法と反応例, アセタ次ル脱保護の新手法-ケタールの存在下にアセタールを脱保護する-(分担)2008

    • Author(s)
      北泰行、藤岡弘道
    • Total Pages
      267
    • Publisher
      シーエムシー出版
    • Related Report
      2007 Annual Research Report
  • [Book] 天然物化学, 植物編, マリチジン、ガランタミンおよび関連アルカロイド2007

    • Author(s)
      北泰行, 他(分担)
    • Total Pages
      12
    • Publisher
      アイピーシー出版社
    • Related Report
      2009 Final Research Report
  • [Book] 天撚物化学, 植物編, 分担, マリチジン、ガランタミンおよび関連アルカロイド(分担)2007

    • Author(s)
      北泰行, 他
    • Total Pages
      12
    • Publisher
      アイピーシー出版社
    • Related Report
      2007 Annual Research Report
  • [Book] Topics in Current Chemistry, "Sulfur-Mediated Rearrangements 1", 274, Recent Advances in Pummerer Reactions. (分担)2007

    • Author(s)
      北泰行, 他
    • Total Pages
      42
    • Publisher
      Springer
    • Related Report
      2007 Annual Research Report
  • [Book] 天然物化学 植物編2007

    • Author(s)
      Kita, Yasuyukie, et. al. (分担)
    • Total Pages
      12
    • Publisher
      アイピーシー出版
    • Related Report
      2006 Annual Research Report
  • [Book] Encyclopedia of reagents for organic synthesis2006

    • Author(s)
      北泰行, 他(分担)
    • Total Pages
      3
    • Publisher
      Wiley John Wiley & Sons Ltd
    • Related Report
      2009 Final Research Report
  • [Book] 人名反応に学ぶ有機合成戦略2006

    • Author(s)
      Kita, Yasuyuki (分担)
    • Total Pages
      20
    • Publisher
      東京化学同人
    • Related Report
      2006 Annual Research Report
  • [Book] 化学者たちの感動の瞬聞 第2部 天然物合成編個から広がる研究2006

    • Author(s)
      Kita, Yasuyuki(分担)
    • Total Pages
      5
    • Publisher
      東京化学同人
    • Related Report
      2006 Annual Research Report
  • [Book] Encyclopedia of Reagents for Organic Synthesis2006

    • Author(s)
      Kita, Yasuyukie, et. al. (分担)
    • Total Pages
      3
    • Publisher
      Wiley John Wiley & Sons Ltd
    • Related Report
      2006 Annual Research Report
  • [Patent(Industrial Property Rights)] アルコール酸化物の製造方法2009

    • Inventor(s)
      土肥寿文, 他
    • Industrial Property Rights Holder
      土肥寿文, 他
    • Filing Date
      2009-03-31
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] アルコール酸化物の製造方法2009

    • Inventor(s)
      土肥寿文, 北泰行, 他
    • Industrial Property Rights Holder
      土肥寿文, 北泰行, 他
    • Filing Date
      2009-03-31
    • Related Report
      2008 Annual Research Report
  • [Patent(Industrial Property Rights)] Preparation of fluorescent oleamide derivatives having gap binding inhibition activity2008

    • Inventor(s)
      北泰行, 他
    • Industrial Property Rights Holder
      北泰行, 他
    • Acquisition Date
      2008-02-08
    • Related Report
      2007 Annual Research Report
  • [Patent(Industrial Property Rights)] ヨウ化物と、それを用いた酸化的不斉スピロ環形成法2007

    • Inventor(s)
      土肥寿文, 北泰行, 他
    • Industrial Property Rights Holder
      大阪大学
    • Filing Date
      2007-12-20
    • Related Report
      2009 Final Research Report
  • [Patent(Industrial Property Rights)] ヨウ化物と、それを用いた酸化的不斉スピロ環形成方法2007

    • Inventor(s)
      土肥寿文、北泰行, 他
    • Industrial Property Rights Holder
      大阪大学
    • Filing Date
      2007-12-20
    • Related Report
      2007 Annual Research Report

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Published: 2006-04-01   Modified: 2016-04-21  

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