|Budget Amount *help
¥17,550,000 (Direct Cost: ¥13,500,000、Indirect Cost: ¥4,050,000)
Fiscal Year 2021: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2020: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2019: ¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2018: ¥8,190,000 (Direct Cost: ¥6,300,000、Indirect Cost: ¥1,890,000)
|Outline of Final Research Achievements
Land plants have C-to-U RNA editing in chloroplasts and mitochondria. Many types of RNA editing factors have been identified last decades, their detailed molecular function is still unclear. In this research project, we successfully reproduced RNA editing reaction in E.coli as well as in vitro. Furthermore, we determined 3D structure of RNA editing enzyme, which has been enigmatic for long time, and revealed its molecular mechanism for catalysis.