| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2020: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2019: ¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2018: ¥7,020,000 (Direct Cost: ¥5,400,000、Indirect Cost: ¥1,620,000)
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| Outline of Final Research Achievements |
This study investigated the thermal and circulatory responses to hypobaric hypoxia and cold environment that requires conflicting vascular responses such as vasodilation and vasoconstriction. We observed hypobaric hypoxia-induced vasodilation at the forehead and the trunk of the body even during cold exposure, although vasoconstriction occurred in peripheral parts such as fingers. We investigated the influence factors that cause individual differences in the circulatory reactions under the combine environment between hypobaric hypoxia and cold by evaluating the vasomotor response induced by either cold or hypobaric hypoxia, adaptive changes in oxygen saturation and autonomic nervous function to hypobaric hypoxia, and gene expression induced by each environments.
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