• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

口腔機能維持による健康寿命延伸のエビデンスの確立:2600人の9年間コホート研究

Research Project

Project/Area Number 18H02990
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 57050:Prosthodontics-related
Research InstitutionOsaka University

Principal Investigator

池邉 一典  大阪大学, 歯学研究科, 教授 (70273696)

Co-Investigator(Kenkyū-buntansha) 増井 幸恵  地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 (10415507)
松田 謙一  大阪大学, 歯学研究科, 招へい教員 (80448109)
小川 泰治  大阪大学, 歯学研究科, 招へい教員 (10543481)
Project Period (FY) 2018-04-01 – 2021-03-31
Project Status Granted (Fiscal Year 2020)
Budget Amount *help
¥17,290,000 (Direct Cost: ¥13,300,000、Indirect Cost: ¥3,990,000)
Fiscal Year 2020: ¥6,370,000 (Direct Cost: ¥4,900,000、Indirect Cost: ¥1,470,000)
Fiscal Year 2019: ¥5,590,000 (Direct Cost: ¥4,300,000、Indirect Cost: ¥1,290,000)
Fiscal Year 2018: ¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Keywords口腔機能 / 健康長寿 / 認知機能 / 運動機能 / 健康寿命 / 咬合力 / サルコペニア / 高齢者
Outline of Annual Research Achievements

目的:口腔とサルコペニアとの関連が認められることが,これまでいくつか報告されている.しかしながら,口腔機能低下症の診断項目である舌圧や舌口唇運動機能などの口腔機能とサルコペニアとの関連についての報告はほとんどみられない.そこで本研究では,口腔機能とサルコペニアとの関連について検討を行うことを目的とした.
方法:対象者は,70歳代80歳代の地域在住高齢者455名(男性223名,女性232名)とした.サルコペニアの判定は,Asia Working Group for Sarcopenia (AWGS)の診断基準に基づき行った.対象者は,舌圧,舌口唇運動機能,咬合力,咀嚼能率,嚥下機能において,それぞれ健常群・低下群の2群に分類された.なお,低下の判定は口腔機能低下症の診断基準に従った.口腔機能とサルコペニア罹患の関連について,これまで報告されてきた危険因子を調整したロジスティック回帰分析により検討を行った.有意水準は5%とした.
結果:サルコペニアの罹患者は,109名(21.8%)であった.ロジスティック回帰分析の結果,咬合力(オッズ比1.89,95%信頼区間1.03-3.44)は,性別,年齢,残存歯数などを調整した上でもサルコペニア罹患と有意な関連を認めた.その一方で,その他の舌圧,舌口唇運動機能.咀嚼能率,嚥下機能などの口腔機能は,サルコペニア罹患と有意な関連を認めなかった.
結論:地域在住高齢者において,咬合力は,サルコペニア罹患に関連することが明らかとなった.

Current Status of Research Progress
Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

参加者数も予定通りであり,データの整理,分析も順調である.
ただし,国際学会の中止によって,成果発表の機会が失われたのが誤算であった.

Strategy for Future Research Activity

次年度も,今年度同様,参加者の確保,データ整理,分析を遅滞なく進める.
ただし,新型コロナウィルス感染拡大の影響で,高齢者の調査を予定通り行えるのか,懸念している.

Report

(2 results)
  • 2019 Annual Research Report
  • 2018 Annual Research Report

Research Products

(10 results)

All 2019 2018

All Journal Article (4 results) (of which Int'l Joint Research: 3 results,  Peer Reviewed: 4 results,  Open Access: 4 results) Presentation (6 results) (of which Int'l Joint Research: 6 results,  Invited: 1 results)

  • [Journal Article] Lack of posterior occlusal support predicts the reduction in walking speed in 80‐year‐old Japanese adults: A 3‐year prospective cohort study with propensity score analysis by the SONIC Study Group2019

    • Author(s)
      Hatta Kodai、Ikebe Kazunori、Mihara Yusuke、Gondo Yasuyuki、Kamide Kei、Masui Yukie、Sugimoto Ken、Matsuda Ken‐ichi、Fukutake Motoyoshi、Kabayama Mai、Shintani Ayumi、Ishizaki Tatsuro、 Arai Yasumichi、Rakugi Hiromi、Maeda Yoshinobu
    • Journal Title

      Gerodontology

      Volume: - Pages: 156-162

    • DOI

      10.1111/ger.12393

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Hyperglycemia in non-obese patients with type 2 diabetes is associated with low muscle mass: The MUSCLES-DM study.2019

    • Author(s)
      Sugimoto K, Tabara Y, Ikegami H, Takata Y, Kamide K, Ikezoe T, Kiyoshige E, Makutani Y, Onuma H, Gondo Y, Ikebe K, Ichihashi N, Tsuboyama T, Matsuda F, Kohara K, Kabayama M, Fukuda M, Katsuya T, Osawa H, Hiromine Y, Rakugi H.
    • Journal Title

      Journal of diabetes investigation

      Volume: 10: Pages: 1471-1479

    • DOI

      10.1111/jdi.13070

    • Related Report
      2019 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Influence of lack of posterior occlusal support on cognitive decline among 80-year-old Japanese pople in a 3-year prospective study2018

    • Author(s)
      Hatta K、Ikebe K、Gondo Y、Kamide K、Masui Y、Inagaki H、Nakagawa T、Matsuda K、Ogawa T、 Inomata C、Takeshita H、Mihara Y、Fukutake M、Kitamura M、Murakami S、Kabayama M、Ishizaki T、 Arai Y、Sugimoto K、Rakugi H、Maeda Y
    • Journal Title

      Geriat Gerontol Int

      Volume: 18 Pages: 1439-1446

    • DOI

      10.1111/ggi.13508

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Relationship between gerotranscendence and oral health-related quality of life2018

    • Author(s)
      Mihara Yusuke、Matsuda Ken-ichi、Hatta Koudai、Gondo Yasuyuki、Masui Yukie、Nakagawa Takeshi、 Kamide Kei、Ishizaki Tatsuro、Arai Yasumichi、Maeda Yoshinobu、Ikebe Kazunori
    • Journal Title

      J Oral Rehabil.

      Volume: 45 Pages: 805-809

    • DOI

      10.1111/joor.12691

    • Related Report
      2018 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Presentation] Influence of occlusal force on decline in BMI among elders2019

    • Author(s)
      Fukutake M, Hatta K, Sato H, Mihara Y, Takeshita H, Enoki K, Matsuda K, Gondo Y, Kamide K, Arai Y, Ishizaki T, Masui Y, Maeda Y, Ikebe K
    • Organizer
      I.A.D.R. General Session
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Occlusal Force Predict Decline in Cognitive Function in 3-Year2019

    • Author(s)
      Hatta K, Fukutake M, Sato H, Mihara Y, Hagino H, Enoki K, Murotani Y, Matsuda K, Maeda Y, Ikebe K
    • Organizer
      International College of Prosthodontists
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Associations between sarcopenia and oral functions in old-old Japnese2019

    • Author(s)
      Murotani Y, Ikebe K
    • Organizer
      International Association for Dental Research Asia-Pacific Region
    • Related Report
      2019 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Occlusal contacts predict decline in cognitive function in 3-years2018

    • Author(s)
      Hatta K, Fukutake M, Sato H, Mihara Y, Matsuda K, Gondo Y, Kamide K, Masui Y, Ishizaki T, Arai Y, Sugimoto K, Inomata C, Takeshita H, Enoki K, Maeda Y, Ikebe K
    • Organizer
      IADR
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of occlusal force on malnutrition in older adults2018

    • Author(s)
      Fukutake M, Hatta K, Sato H, Mihara Y, Inomata C, Takeshita H, Enoki K, Matsuda K, Gondo Y, Kamide K, Arai Y, Ishizaki T, Masui Y, Maeda Y, Ikebe K
    • Organizer
      IADR
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Influence of Mastication on Memory/Cognition During Development and Aging2018

    • Author(s)
      Ikebe K
    • Organizer
      IADR
    • Related Report
      2018 Annual Research Report
    • Int'l Joint Research / Invited

URL: 

Published: 2018-04-23   Modified: 2021-01-27  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi