• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of next-generation MRI technology for observing the microstructure inside a living body in detail with an ultra-fine tomographic image

Research Project

Project/Area Number 18K13764
Research Category

Grant-in-Aid for Early-Career Scientists

Allocation TypeMulti-year Fund
Review Section Basic Section 21030:Measurement engineering-related
Research InstitutionUniversity of Toyama

Principal Investigator

Hasegawa Masaya  富山大学, 学術研究部工学系, 助教 (00807844)

Project Period (FY) 2018-04-01 – 2022-03-31
Project Status Completed (Fiscal Year 2021)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2019: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2018: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
KeywordsMRI / Non-harmonic Analysis / 超精度解析 / 高分解能 / 超精細技術 / 医用断層撮影技術 / Non-Harmonic Analysis
Outline of Final Research Achievements

In this study, we applied NHA, which is a high-accuracy analysis method, to MRI. MRI is a medical tomography device. It is difficult to visualize less than 700 μm with 1.5 Tesla MRI. We have developed an ultra-fine technology that can observe the microstructure. In the experiment, using commercially available processed meat as a physical phantom. The MRI image by FFT was compared with proposed MRI image. From the experiment, in the conventional MRI image, the contrast and rough tissue distribution can be observed, but it is difficult to observe the fine structure. On the other hand, the MRI image by the proposed method greatly suppressed the occurrence of side lobes and showed the possibility of visualizing the density distribution and microstructure of intensity at a distance of about 0.4 mm, which is difficult to express with conventional MRI images.

Academic Significance and Societal Importance of the Research Achievements

MRIを用いて現状よりさらに微細な領域を観察するためには、計測データをより正確に解析し、分解能と磁場強度の依存関係を脱却し、既存のハードウェア性能を極限まで発揮する革新的な解析技術が必要である。低磁場MRIの実計測データを超精度解析し、従来は観察できない微小構造を観察できる可能性を示した。

Report

(5 results)
  • 2021 Annual Research Report   Final Research Report ( PDF )
  • 2020 Research-status Report
  • 2019 Research-status Report
  • 2018 Research-status Report
  • Research Products

    (1 results)

All 2019

All Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] High-resolution MR image by high precision signal analysis method for accurately analyze complex signals2019

    • Author(s)
      Masaya Hasegawa, Ahmad Naif Syaihan Bin Juanda Ruha, Kanna Hirobayashi, Kazuki Fuji, Keizo Takao, Kyo Noguchi, Shigeki Hirobayashi
    • Organizer
      SPIE BiOS, 2019, San Francisco, California, United States
    • Related Report
      2018 Research-status Report
    • Int'l Joint Research

URL: 

Published: 2018-04-23   Modified: 2023-01-30  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi