Research and development of therapeutic antibodies against human rotavirus infection.
Project/Area Number |
19591266
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Pediatrics
|
Research Institution | Fujita Health University |
Principal Investigator |
MORIGUCHI Kyoko Fujita Health University, 医学部, 講師 (60298528)
|
Co-Investigator(Kenkyū-buntansha) |
TANIGUCH Ikoki 藤田保健衛生大学, 医学部, 教授 (40094213)
|
Project Period (FY) |
2007 – 2010
|
Project Status |
Completed (Fiscal Year 2010)
|
Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2007: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
|
Keywords | ヒト型ファージ抗体 / 交叉反応性 / ロタウイルス / ノロウイルス / ファージ抗体 / HRV / ヒト型抗体 / モノクローナル / HuNov / 小児感染症学 / 受動免疫 / 乳酸菌 / 中和 / ヒト型 |
Research Abstract |
Expression system of human antibodies in Lactococcus lactise was established to be enable to produce the molecules persistently in intestine. We also tried to isolate anti-human norovirus antibodies, and 66 clones (42types) including2cross-reactive antibodies were isolated.
|
Report
(6 results)
Research Products
(3 results)