• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Validation system for aging in human egg cells based on carbohydrate structures and in vitro maturation

Research Project

Project/Area Number 19591917
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Obstetrics and gynecology
Research InstitutionNational Research Institute for Child Health and Development

Principal Investigator

TOYODA Masashi  National Research Institute for Child Health and Development, 生殖・細胞医療研究部, 共同研究員 (50392486)

Co-Investigator(Kenkyū-buntansha) HATA Junichi  国立成育医療センター(研究所), 名誉総長 (90051614)
UMEZAWA Akihiro  国立成育医療センター(研究所), 生殖細胞医療研究部, 部長 (70213486)
Project Period (FY) 2007 – 2009
Project Status Completed (Fiscal Year 2009)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2007: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords糖鎖バリデーション / レクチン / 卵子 / 発生
Research Abstract

The molecular mechanism of maturation of ovum is not clear. For validation of mammalian egg maturation processes during development and aging, we investigated the cell surface carbohydrate expression patterns of ovum and ovary using carbohydrate specific antibodies and lectins. As a result, we showed that some specific carbohydrate structures had important roles for development and aging processes of ovum.

Report

(4 results)
  • 2009 Annual Research Report   Final Research Report ( PDF )
  • 2008 Annual Research Report
  • 2007 Annual Research Report
  • Research Products

    (1 results)

All 2008

All Journal Article (1 results)

  • [Journal Article] What can we learn from gene expression profiling of mouse oocytes2008

    • Author(s)
      Hamatani T, Yamada M, Akutsu H, Kuji N, Mochimaru Y, Takano M, Toyoda M, Miyado K, Umezawa A, Yoshimura Y
    • Journal Title

      Reproduction 135(5)

      Pages: 581-592

    • Related Report
      2009 Final Research Report

URL: 

Published: 2007-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi