|Budget Amount *help
¥25,740,000 (Direct Cost: ¥19,800,000、Indirect Cost: ¥5,940,000)
Fiscal Year 2010: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2008: ¥7,150,000 (Direct Cost: ¥5,500,000、Indirect Cost: ¥1,650,000)
Fiscal Year 2007: ¥13,390,000 (Direct Cost: ¥10,300,000、Indirect Cost: ¥3,090,000)
It was investigated and analyzed the effect of foods and nutrients on the inhibition of mammalian DNA polymerase (pol) species, anti-cancer and anti-inflammation. The glycolipids from spinach inhibited the activities of DNA replicative pols and showed anti-tumor activity. The curcumin derivatives showed specific inhibition of pol λ, which is a DNA repair and recombination related pol, and anti-inflammation.