Application of Monolithic Porous Layer on SiWafer -Toward Cell Manipulation for Biotechnology-
| Project/Area Number |
19686014
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Production engineering/Processing studies
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
早瀬 仁則 Tokyo University of Science, 理工学部, 准教授 (70293058)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥26,520,000 (Direct Cost: ¥20,400,000、Indirect Cost: ¥6,120,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2008: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2007: ¥19,890,000 (Direct Cost: ¥15,300,000、Indirect Cost: ¥4,590,000)
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| Keywords | MEMS / 多孔質シリコン / 細胞アレイ / 微細加工 / ナノバイオ / マイクロ・ナノデバイス / 細胞固定 / 徴細加工 |
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| Research Abstract |
Through-chip porous area array was made on a Si chip and cellular array was demonstrated by vacuum suction on the through-chip porous areas. It was expected that the porous area was easily blocked by some substances contained in a cultivation medium. Then the pressure drop through the porous area was measured and it was found that enough suctional fluidic volume can be obtained with a fresh filtrated cultivation medium. Cell immobilization was demonstrated and it was found that cell fragmentation could be induced after the immobilization by applying strong suction.
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Report
(4 results)
Research Products
(13 results)
