Role of astrocyte in synaptic maturation during postnatal developing nucleus tractus solitarius
| Project/Area Number |
19700323
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | Mie University (2008-2009)
Jikei University School of Medicine (2007) |
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Principal Investigator |
TASHIRO Yasura Mie University, 大学院・医学系研究科, 講師 (10398787)
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| Project Period (FY) |
2007 – 2009
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| Project Status |
Completed (Fiscal Year 2009)
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| Budget Amount *help |
¥3,050,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2008: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2007: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | 神経回路形成 / ニューロン・グリア相互作用 / アストロサイト / シナプス / 延髄 / 孤束核 / 血圧調整 / 神経発達 / ラット / 電顕 |
|---|
| Research Abstract |
In developing nervous system, unnecessary synapses are eliminated. In the present study, the timing for glial coverage of small cell soma appears to be consistent with the decrease of axosomatic synapses on the small cells. Axosomatic synapses remained in adult stages under pharmacological inhibition of astrocytic processes extension during neonatal stages. These observations indicats that astrocytes could participate actively in regulating the decrease of axosomatic synapses on small cells in the caudal nucleus tractus solitarius during postnatal development.
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Report
(4 results)
Research Products
(19 results)
