The basic research for searching effective exercise for polymyositis.

• Project/Area Number: 19700438
• Research Category: Grant-in-Aid for Young Scientists (B)
• Allocation Type: Single-year Grants
• Research Field: Rehabilitation science/Welfare engineering
• Research Institution: Nagasaki University
• Principal Investigator: SAKAKIBARA Atsushi Nagasaki University, 病院, 技術職員 (00423624)
• Project Period (FY): 2007 – 2009
• Project Status: Completed (Fiscal Year 2009)
• Budget Amount: ¥2,590,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥390,000); Fiscal Year 2009: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000); Fiscal Year 2008: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2007: ¥900,000 (Direct Cost: ¥900,000)
• Keywords: リハビリテーション / 理学療法学 / 免疫学 / 細胞・組織 / 動物

Research Abstract

The purpose of this study is to grope for the effective motion for polymyositis。 The experiment carried out muscle contraction motion by electric stimulation to the one foot of myositis model rat of two kinds reported in a past。 The model rat used and immunized laminin and myosin for the antigen。 As the result、 there was the increase of necrosis cell and regenerative cell of stimulated foot than not stimulated foot。 However、 it was not possible to compare between model rats of two kinds without establishing the reproducibility of the model rat preparation。 Future problem is to establish the reproducibility of the model rat preparation first。