Molecular mechanism of urothelium regulating bladder function
| Project/Area Number |
20390425
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Urology
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| Research Institution | Kyoto University |
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Principal Investigator |
NISHIYAMA Hiroyuki Kyoto University, 大学院・医学研究科, 准教授 (20324642)
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| Co-Investigator(Kenkyū-buntansha) |
OGAWA Osamu 京都大学, 大学院・医学研究科, 教授 (90260611)
NAKAMURA Eijiro 京都大学, 大学院・医学研究科, 講師 (90293878)
KANEMATSU Akihiro 京都大学, 大学院・医学研究科, 講師 (90437202)
YOSHIMURA Kouji 京都大学, 大学院・医学研究科, 講師 (40397542)
SODA Takeshi 京都大学, 大学院・医学研究科, 助教 (50422928)
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| Project Period (FY) |
2008 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥17,420,000 (Direct Cost: ¥13,400,000、Indirect Cost: ¥4,020,000)
Fiscal Year 2010: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2009: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2008: ¥7,800,000 (Direct Cost: ¥6,000,000、Indirect Cost: ¥1,800,000)
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| Keywords | 排尿障害 / 膀胱機能 / 尿路上皮 / 分子生物学 |
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| Research Abstract |
In this project, we engaged in clarification of the mechanism underlying change in bladder function with the molecules secreted from urothelium under stimuli. We demonstrated the physiological role of urothelium and the clinical condition of the bladder disease related with dysfunctional urothelium with combination of conventional pharmacological analysis, molecular biological analysis and new voiding behavior analysis.
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Report
(4 results)
Research Products
(13 results)
