| Project/Area Number |
20591039
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|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neurology
|
|---|
| Research Institution | National Cardiovascular Center Research Institute |
|---|
Principal Investigator |
TOYODA Kazunori National Cardiovascular Center Research Institute, 脳血管内科, 部長 (50275450)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
KOGA Masatoshi 独立行政法人国立循環器病研究センター, 脳血管内科, 医長 (30512230)
|
|---|
| Project Period (FY) |
2008 – 2010
|
| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2008: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
|---|
| Keywords | 脳梗塞 / 急性期 / 血栓溶解療法 / 血圧 / 降圧 / 急性期脳梗塞 / 高血圧 / rt-PA静注療法 |
|---|
| Research Abstract |
Low levels of systolic blood presssure (BP), diastolic BP, and heart rate (HR) on day 2, as well as low HR level on day 8, assessed using ambulatory BP monitoring were associated with 3-month favorable outcomes in acute stroke patients. Low levels of systolic BP, pulse pressure, and HR during the initial 24 hours after rt-PA therapy, especially at 8 hours thereafter, were associated with 3-month favorable outcomes in the patients treated with rt-PA.
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