| Project/Area Number |
20750009
|
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Physical chemistry
|
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| Research Institution | Kyoto University |
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Principal Investigator |
ITO Takeo Kyoto University, 大学院・工学研究科, 助教 (80378801)
|
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| Research Collaborator |
NISHIMOTO Sei-ichi 京都大学, 大学院・工学研究科, 教授 (10115909)
TANABE Kazuhito 京都大学, 大学院・工学研究科, 准教授 (40346086)
YAMADA Hisatsugi 京都大学, 大学院・工学研究科, 助教 (80512764)
|
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| Project Period (FY) |
2008 – 2009
|
| Project Status |
Completed (Fiscal Year 2009)
|
| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2008: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
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| Keywords | 生物物理化学・DNA内電子移動 / 核酸 / 時間分解分光測定 / 核酸塩基損傷 / 電子移動 / アプタマー |
|---|
| Research Abstract |
Effects of DNA structure on the DNA-mediated electron transfer efficiency were quantitatively investigated using DNA containing novel photo-induced electron donors. It was suggested that local structural changes and electron affinities of DNA sequences as well as redox properties of the electron donors highly affect the electron transfer efficiency.
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