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Personalized brain-machine interface based on brain features

Research Project

Project/Area Number 20H04236
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Review Section Basic Section 61020:Human interface and interaction-related
Research InstitutionNational Institute of Advanced Industrial Science and Technology

Principal Investigator

Kasahara Kazumi  国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 主任研究員 (30706164)

Co-Investigator(Kenkyū-buntansha) 澤田 和彦  つくば国際大学, 医療保健学部, 教授(移行) (10284324)
LI Yuzhe  沖縄科学技術大学院大学, 神経計算ユニット, スタッフサイエンティスト (30815436)
肥後 範行  国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 研究グループ長 (80357839)
Project Period (FY) 2020-04-01 – 2023-03-31
Project Status Completed (Fiscal Year 2023)
Budget Amount *help
¥17,940,000 (Direct Cost: ¥13,800,000、Indirect Cost: ¥4,140,000)
Fiscal Year 2022: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2021: ¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2020: ¥8,580,000 (Direct Cost: ¥6,600,000、Indirect Cost: ¥1,980,000)
Keywordsブレイン・マシン・インターフェイス / BMI / MRI / 脳波 / 個人差 / イメージ / Brain-Machine Interface / Brain-Computer Interface / fMRI / 可塑性
Outline of Research at the Start

ブレイン・マシン・インターフェイスは、患者の脳活動に基づいてパソコンや車椅子などの機械を動かすことで、病気やけがにより失われた脳機能を代替する技術である。しかし、その操作能力には個人差があり、上手く操作出来ない患者も多い。そこで本研究は、ブレイン・マシン・インターフェイスの操作時に、被験者が「何をどのように(what, how)」イメージし、「何秒で(how long)」学習するかについて、その個人差を脳の特徴から分析することで、操作能力の個人差を解決するテーラーメイド・ブレイン・マシン・インターフェイスを開発する。

Outline of Final Research Achievements

Brain-Machine Interface (BMI) is a technology that is being developed to replace lost brain functions due to illness or injury by reading a patient's brain activity and operating a machine based on that activity. However, there is individual variability in the ability to control BMI, and many subjects cannot operate it well, and the reasons for this variability are not yet known. Therefore, we aimed to develop a BMI that everyone can utilize and to clarify the individual variability in operating ability based on individual brain variability.
In this study, we revealed the individual variability in the imagery method and brain network involved in BMI control and found novel insights into the effects of brain stimulation on BMI control.

Academic Significance and Societal Importance of the Research Achievements

本研究は、ブレイン・マシン・インターフェイスの操作に関わる個人差を明らかにした。本研究の結果を手掛かりに、被験者各々に適したイメージの方法や被験者各々の脳の特徴に合わせたテーラーメイドな技術の第一歩となるべく、引き続き研究を推進する。個人差解明とテーラーメイド技術によって、誰でも気軽にブレイン・マシン・インターフェイスを利用できるようになれば、脳機能代替技術としてだけでなく、リハビリテーション支援や能力拡張の手段として、利用が大きく広がる可能性を秘めている。

Report

(4 results)
  • 2023 Final Research Report ( PDF )
  • 2022 Annual Research Report
  • 2021 Annual Research Report
  • 2020 Annual Research Report
  • Research Products

    (13 results)

All 2023 2022 2021 2020

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 1 results) Presentation (10 results) (of which Int'l Joint Research: 2 results,  Invited: 1 results)

  • [Journal Article] Basal ganglia-cortical connectivity underlies self-regulation of brain oscillations in humans2022

    • Author(s)
      Kasahara Kazumi、DaSalla Charles S.、Honda Manabu、Hanakawa Takashi
    • Journal Title

      Communications Biology

      Volume: 5 Issue: 1 Pages: 712-712

    • DOI

      10.1038/s42003-022-03665-6

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] ブレイン・マシン・インターフェースに関する脳の個人差とテーラーメイド化への知見2022

    • Author(s)
      笠原和美、花川隆
    • Journal Title

      LIFE2022論文集

      Volume: - Pages: 241-243

    • Related Report
      2022 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of transcranial direct current stimulation in brain-computer interface2021

    • Author(s)
      Kazumi Kasahara, Tatsuhiro Nakamura, Kazumasa Uehara, Yousuke Ogata, Kenji Doya, Takashi Hanakawa
    • Journal Title

      Proceedings of 2021 IEEE 3rd Global Conference on Life Sciences and Technologies (LifeTech)

      Volume: - Pages: 462-462

    • Related Report
      2020 Annual Research Report
    • Peer Reviewed
  • [Presentation] Brain-Computer Interfaceの操作に関わる脳の個人差2023

    • Author(s)
      笠原和美
    • Organizer
      産業技術総合研究所人間情報インタラクション研究部門シンポジウム2022 ~脳の変化~
    • Related Report
      2022 Annual Research Report
  • [Presentation] 運動想像を用いたBrain-Computer Interface操作成績と強化学習パターンの関係2023

    • Author(s)
      大隈 玲志, 片平健太郎, 木村健太, 笠原和美
    • Organizer
      第33回日本神経回路学会全国大会
    • Related Report
      2022 Annual Research Report
  • [Presentation] Neural connectivity among different layers changes at different brain states.2023

    • Author(s)
      Li Y, Doya K
    • Organizer
      The 22nd Winter Workshop on Mechanism of Brain and Mind.
    • Related Report
      2022 Annual Research Report
  • [Presentation] Dual Bayesian PCA for Factor Analysis on Calcium imaging data.2022

    • Author(s)
      Li Y, Doya K
    • Organizer
      The 45th Annual Meeting of the Japan Neuroscience Society (Neuron 2022).
    • Related Report
      2022 Annual Research Report
  • [Presentation] BCI制御に関わる神経基盤のマルチモーダル計測2021

    • Author(s)
      花川隆、笠原和美
    • Organizer
      第32 回実社会におけるマルチモーダル脳情報応用技術研究会
    • Related Report
      2021 Annual Research Report
    • Invited
  • [Presentation] Investigation of information flow and temporal-spatial organization of neurons across cortical layers from multi-depth two-photon imaging data.2021

    • Author(s)
      Yuzhe Li, Akihiro Funamizu, Bernd Kuhn, Kenji Doya
    • Organizer
      The 44th Annual Meeting of the Japan Neuroscience Society / The 1st CJK International Meeting.
    • Related Report
      2021 Annual Research Report
  • [Presentation] Effects of transcranial direct current stimulation in brain-computer interface2021

    • Author(s)
      Kazumi Kasahara, Tatsuhiro Nakamura, Kazumasa Uehara, Yousuke Ogata, Kenji Doya, Takashi Hanakawa
    • Organizer
      IEEE LifeTech 2021
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Changes in the basal ganglia-thalamic functional connectivity induced by longitudinal motor training in mice2020

    • Author(s)
      Kazumi Kasahara, Kenji Doya
    • Organizer
      Neuroscience 2020(第43回日本神経科学大会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] Investigation of temporal and spatial origination of neural network in sensory cortex2020

    • Author(s)
      Yuzhe Li, Kenji Doya
    • Organizer
      Neuroscience 2020(第43回日本神経科学大会)
    • Related Report
      2020 Annual Research Report
  • [Presentation] Neuron hubs distributed differently in deep layers and superficial layers in different brain states2020

    • Author(s)
      Yuzhe Li, Kenji Doya
    • Organizer
      The 1st Asia-Pacific Computational and Cognitive Neuroscience Conference
    • Related Report
      2020 Annual Research Report
    • Int'l Joint Research

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Published: 2020-04-28   Modified: 2025-01-30  

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