Development of motor functions by formation of local neural circuits
| Project/Area Number |
21700344
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| Research Category |
Grant-in-Aid for Young Scientists (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Neuroscience in general
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| Research Institution | The University of Tokyo |
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Principal Investigator |
KOHSAKA Hiroshi 東京大学, 大学院・理学系研究科, 助教 (20431900)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 発生・発達・再生神経科学 / 神経回路 / 神経科学 / 光生理学 / 遺伝学 / 行動学 / イメージング / 制御 / 電気生理学 / 発生・分化 |
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| Research Abstract |
Network of neurons generates variety of animal's activities such as moving, sensing and memorizing. While the properties of each neuron have been deeply examined, how assembly of neurons creates coherent and coordinated functions remains to be clarified. In this study, we dissected Drosophila larval motor circuits that generate spatiotemporal patterns of locomotion. We succeeded in identification of a group of interneurons(we named them "PMSI") which control the speed of the larval locomotion. By detailed analysis of PMSI using Ca imaging and optogenetics, we revealed some of the mechanisms how motor circuits regulate speed of locomotion.
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Report
(4 results)
Research Products
(47 results)
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[Presentation] Imaging activity propagation in the larval motor circuits that regulate peristalsis.2010
Author(s)
Kohsaka, H., Nii, R., Nakagawa, Y., Inada, K., Nose, A
Organizer
NeuroFly 2010
Place of Presentation
Manchester, UK
Related Report
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